{ "uniprot_canonical_ac": "P53086-1", "uniprot_ac": "P53086", "uniprot_id": "KIP3_YEAST", "mass": { "chemical_mass": 91090.0, "monoisotopic_mass": 91090.0 }, "refseq": { "ac": "NP_011299", "name": "tubulin-dependent ATPase KIP3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011299" }, "gene_names": [ { "name": "KIP3", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P53086", "id": "P53086" }, { "name": "KIP3", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011299", "id": "NP_011299" } ], "protein_names": [ { "name": "Kinesin-like protein KIP3", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P53086" }, { "name": "tubulin-dependent ATPase KIP3", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011299", "id": "NP_011299" } ], "function": [], "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - 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"https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": 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"name": "Colorectal cancer", "description": "Colorectal cancer" } ], "evidence": [ { "id": "9256", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P53086", "url": "https://www.uniprot.org/uniprot/P53086" } ], "common_name": "Yeast" } ], "gene": [ { "name": "KIP3", "url": "https://www.uniprot.org/uniprot/P53086", "locus": {} } ], "crossref": [ { "id": "5.6.1.3", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=5.6.1.3&UniProtAcc=P53086", "database": "BRENDA", "categories": [ "Enzyme and Pathway" ] }, { "id": "cd01370", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01370", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "852655", "url": "https://www.ncbi.nlm.nih.gov/gene/852655", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "P53086", "url": "https://www.ebi.ac.uk/intact/interactors/id:P53086*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "sce:YGL216W", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YGL216W", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CVDDKML", "url": "https://omabrowser.org/oma/group/CVDDKML/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "5476186at2759", "url": "http://www.orthodb.org/?query=5476186at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47969", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47969", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47969:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47969:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "http://pfam.xfam.org/family/PF00225", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_P53086", "url": "http://purl.obolibrary.org/obo/PR_P53086", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_011299", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011299", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "S000003184", "url": "https://www.yeastgenome.org/locus/S000003184", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P53086", "url": "https://www.uniprot.org/uniprot/P53086", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P53086-1", "url": "https://www.uniprot.org/uniprot/P53086-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNVPETRQSSIVVAIRVRPFTSMEKTRLVNEASGAEANFPGLGDSSLILPMSNNSDSDIDIDAEEGSTRSKRNSLLRRKVIRPEGIRKIVDCVDDRMLIFDPADRNPLNKVSDQVLNSMRARATKATASSINNSNATNKFSSQRRRHGGEIKFVFDKLFDETSSQARVYKETTSPLLDSVLDGFNSTVFAYGATGCGKTYTVSGTPSQPGIIFLAMEELFNKITDLKDEKDFEISLSYLEIYNERIRDLLKPETPSKRLVIREDTQNHIKVANLSYHHPNTVEDVMDLVVQGNINRTTSPTEANEVSSRSHAVLQIHIMQTNKLVDLTSQHTFATLSIIDLAGSERAAATRNRGIRLHEGANINRSLLALGNCINALCLNDGSRSCHIPYRDSKLTRLLKFSLGGNCKTVMIVCISPSSSHYDETLNTLKYANRAKEIKTKIIRNQQSLSRHVGSYLKMITEQKRQIEELREREEKMISLKLTKYKLNKEKIQLAINECVNRVQQTYAGVETYQVAKTLKSLILCKRRFLQMVKLEVDNLILLFEREESTAAEMQPVISNCRMISGQLYNKIHELEMKFDETDTLSSVIHQVHSIDLNKLREMEDWDETYDLVYLESCLNQISELQRNEILVNSSIMTEKLMSDPGLNSRFKFLSKWLMNRTPNIESIIQDLVHIDEEFESFARTFIANPDSNFTNTNINIINTTAADLAVPAETLQRQNFSQKKVKWTSPDLSPSPMIEPQPELEPELHQDQDAIASEVDVSMQDTTFNEQGPSTPSAPTTAVPRRKMRSSLLTHQSLLATARK", "length": 805, "header": "sp|P53086-1|KIP3_YEAST Isoform 1 of Kinesin-like protein KIP3 OS=Saccharomyces cerevisiae S288C OX=559292 GN=KIP3 PE=1 SV=1 CANONICAL=P53086-1" }, "isoforms": [ { "isoform_ac": "P53086-1", "url": "", "sequence": { "sequence": "MNVPETRQSSIVVAIRVRPFTSMEKTRLVNEASGAEANFPGLGDSSLILPMSNNSDSDIDIDAEEGSTRSKRNSLLRRKVIRPEGIRKIVDCVDDRMLIFDPADRNPLNKVSDQVLNSMRARATKATASSINNSNATNKFSSQRRRHGGEIKFVFDKLFDETSSQARVYKETTSPLLDSVLDGFNSTVFAYGATGCGKTYTVSGTPSQPGIIFLAMEELFNKITDLKDEKDFEISLSYLEIYNERIRDLLKPETPSKRLVIREDTQNHIKVANLSYHHPNTVEDVMDLVVQGNINRTTSPTEANEVSSRSHAVLQIHIMQTNKLVDLTSQHTFATLSIIDLAGSERAAATRNRGIRLHEGANINRSLLALGNCINALCLNDGSRSCHIPYRDSKLTRLLKFSLGGNCKTVMIVCISPSSSHYDETLNTLKYANRAKEIKTKIIRNQQSLSRHVGSYLKMITEQKRQIEELREREEKMISLKLTKYKLNKEKIQLAINECVNRVQQTYAGVETYQVAKTLKSLILCKRRFLQMVKLEVDNLILLFEREESTAAEMQPVISNCRMISGQLYNKIHELEMKFDETDTLSSVIHQVHSIDLNKLREMEDWDETYDLVYLESCLNQISELQRNEILVNSSIMTEKLMSDPGLNSRFKFLSKWLMNRTPNIESIIQDLVHIDEEFESFARTFIANPDSNFTNTNINIINTTAADLAVPAETLQRQNFSQKKVKWTSPDLSPSPMIEPQPELEPELHQDQDAIASEVDVSMQDTTFNEQGPSTPSAPTTAVPRRKMRSSLLTHQSLLATARK", "length": 805, "header": "sp|P53086-1|KIP3_YEAST Isoform 1 of Kinesin-like protein KIP3 OS=Saccharomyces cerevisiae S288C OX=559292 GN=KIP3 PE=1 SV=1 CANONICAL=P53086-1" }, "locus": { "chromosome": "VII", "start_pos": 87299, "end_pos": 84885, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "YGL216W_mRNA", "url": "https://www.ensembl.org/id/YGL216W_mRNA" }, { "database": "Ensembl Peptide", "id": "YGL216W", "url": "https://www.ensembl.org/id/YGL216W" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 55, "end_pos": 55, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P53086", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P53086" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "P53086", "url": "https://www.yeastgenome.org/locus/P53086" } ], "site_lbl": "Ser55" }, { "start_pos": 57, "end_pos": 57, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": 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