{ "uniprot_canonical_ac": "P49803-1", "uniprot_ac": "P49803", "uniprot_id": "RGS7_RAT", "mass": { "chemical_mass": 55691.0, "monoisotopic_mass": 55691.0 }, "refseq": { "ac": "NP_062216", "name": "regulator of G-protein signaling 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_062216" }, "gene_names": [ { "name": "Rgs7", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P49803", "id": "P49803" }, { "name": "Rgs7", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_062216", "id": "NP_062216" } ], "protein_names": [ { "name": "Regulator of G-protein signaling 7", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P49803" }, { "name": "RGS7", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P49803" }, { "name": "regulator of G-protein signaling 7", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_062216", "id": "NP_062216" } ], "function": [ { "annotation": "GTPase activator component of the RGS7-GNB5 complex that regulates G protein-coupled receptor signaling cascades. The RGS7-GNB5 complex acts as an inhibitor signal transduction by promoting the GTPase activity of G protein alpha subunits, such as GNAO1, thereby driving them into their inactive GDP-bound form. May play a role in synaptic vesicle exocytosis (By similarity). Glycine-dependent regulation of the RGS7-GNB5 complex by GPR158 affects mood and cognition via its ability to regulate neuronal excitability in L2/L3 pyramidal neurons of the prefrontal cortex (By similarity). Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling (PubMed:10092682).", "evidence": [ { "database": "UniProtKB", "id": "P49803", "url": "https://www.uniprot.org/uniprot/P49803#function" }, { "database": "UniProtKB", "id": "P49802", "url": "https://www.uniprot.org/uniprot/P49802#function" }, { "database": "UniProtKB", "id": "O54829", "url": "https://www.uniprot.org/uniprot/O54829#function" }, { "database": "PubMed", "id": "10092682", "url": "https://glygen.org/publication/PubMed/10092682" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "P49803", "url": "https://www.uniprot.org/uniprot/P49803" } ], "common_name": "Rat" } ], "gene": [ { "name": "Rgs7", "url": "https://www.uniprot.org/uniprot/P49803", "locus": { "chromosome": "13", "start_pos": 86979279, "end_pos": 87408888, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000021984", "url": "https://www.ensembl.org/id/ENSRNOG00000021984" } ] } } ], "crossref": [ { "id": "ENSRNOG00000021984", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000021984", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00068", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00068", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04450", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04450", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08738", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08738", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "54296", "url": "https://www.ncbi.nlm.nih.gov/gene/54296", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036284", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036284", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:54296", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:54296", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FWEPENT", "url": "https://omabrowser.org/oma/group/FWEPENT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "22856at2759", "url": "http://www.orthodb.org/?query=22856at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45746", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45746", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45746:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45746:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00610", "url": "http://pfam.xfam.org/family/PF00610", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00615", "url": "http://pfam.xfam.org/family/PF00615", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00631", "url": "http://pfam.xfam.org/family/PF00631", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF18148", "url": "http://pfam.xfam.org/family/PF18148", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_P49803", "url": "http://purl.obolibrary.org/obo/PR_P49803", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-RNO-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-418594", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-RNO-6814122", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6814122", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_062216", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_062216", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "3570", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=3570", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A8I5YBW3", "url": "https://www.uniprot.org/uniprot/A0A8I5YBW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I5YBW3-1", "url": "https://www.uniprot.org/uniprot/A0A8I5YBW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6AAQ8", "url": "https://www.uniprot.org/uniprot/A0A8I6AAQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6AAQ8-1", "url": "https://www.uniprot.org/uniprot/A0A8I6AAQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6AKV4", "url": "https://www.uniprot.org/uniprot/A0A8I6AKV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6AKV4-1", "url": "https://www.uniprot.org/uniprot/A0A8I6AKV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D3ZWG2", "url": "https://www.uniprot.org/uniprot/D3ZWG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D3ZWG2-1", "url": "https://www.uniprot.org/uniprot/D3ZWG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P49803", "url": "https://www.uniprot.org/uniprot/P49803", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P49803-1", "url": "https://www.uniprot.org/uniprot/P49803-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQGNNYGQTSNGVAEESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELHRQIKYWQIQLDRHRLKMSKVADSLLSYTEQYVEYDPFLVPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIREVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKRKGRNIPIFPCHKNCTPTLRASTNLL", "length": 477, "header": "sp|P49803-1|RGS7_RAT Isoform 1 of Regulator of G-protein signaling 7 OS=Rattus norvegicus OX=10116 GN=Rgs7 PE=1 SV=2 CANONICAL=P49803-1" }, "isoforms": [ { "isoform_ac": "A0A8I5YBW3-1", "url": "", "sequence": { "sequence": "MAQGNNYGQTSNGVAEESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELHRQIKYWQIQLDRHRLKMSKVADSLLSYTEQYVEYDPFLVPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIREVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKRKRCHERLLHAVLSPRAFV", "length": 470, "header": "tr|A0A8I5YBW3-1|A0A8I5YBW3_RAT Computationally mapped isoform of Regulator of G-protein signaling 7 OS=Rattus norvegicus OX=10116 GN=Rgs7 PE=4 SV=1 CANONICAL=P49803-1" }, "locus": { "chromosome": "13", "start_pos": 87407429, "end_pos": 86987073, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000107041.1", "url": "https://www.ensembl.org/id/ENSRNOT00000107041.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000076773.1", "url": "https://www.ensembl.org/id/ENSRNOP00000076773.1" } ] } }, { "isoform_ac": "A0A8I6AAQ8-1", "url": "", "sequence": { "sequence": "MAQGNNYGQTSNGVAEESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELHRQIKYWQIQLDRHRLKMSKVADSLLSYTEQYVEYDPFLVPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIREVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKRKGKSLTSKRLTSLVQSY", "length": 469, "header": "tr|A0A8I6AAQ8-1|RGS7_RAT Computationally mapped isoform of Regulator of G-protein signaling 7 OS=Rattus norvegicus OX=10116 GN=Rgs7 PE=1 SV=1 CANONICAL=P49803-1" }, "locus": { "chromosome": "13", "start_pos": 87407429, "end_pos": 86979941, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000112294.1", "url": "https://www.ensembl.org/id/ENSRNOT00000112294.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000090982.1", "url": "https://www.ensembl.org/id/ENSRNOP00000090982.1" } ] } }, { "isoform_ac": "A0A8I6AKV4-1", "url": "", "sequence": { "sequence": "MAQGNNYGQTSNGVAEESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELHRQIKYWQIQLDRHRLKMSKVADSLLSYTEQYVEYDPFLVPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIREVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKRKVLVLCDLS", "length": 461, "header": "tr|A0A8I6AKV4-1|A0A8I6AKV4_RAT Computationally mapped isoform of Regulator of G-protein signaling 7 OS=Rattus norvegicus OX=10116 GN=Rgs7 PE=4 SV=1 CANONICAL=P49803-1" }, "locus": { "chromosome": "13", "start_pos": 87407429, "end_pos": 86998741, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000106278.1", "url": "https://www.ensembl.org/id/ENSRNOT00000106278.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000094085.1", "url": "https://www.ensembl.org/id/ENSRNOP00000094085.1" } ] } }, { "isoform_ac": "D3ZWG2-1", "url": "", "sequence": { "sequence": "LKLGKYFNNTREGMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELHRQIKYWQIQLDRHRLKMSKVADSLLSYTEQYVEYDPFLVPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIREVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKRKGRNIPIFPCHKNCTPTLRASTNLL", "length": 464, "header": "tr|D3ZWG2-1|D3ZWG2_RAT Computationally mapped isoform of Regulator of G-protein signaling 7 OS=Rattus norvegicus OX=10116 GN=Rgs7 PE=1 SV=3 CANONICAL=P49803-1" }, "locus": { "chromosome": "13", "start_pos": 87179776, "end_pos": 86996636, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000065041.3", "url": "https://www.ensembl.org/id/ENSRNOT00000065041.3" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000063631.3", "url": "https://www.ensembl.org/id/ENSRNOP00000063631.3" } ] } }, { "isoform_ac": "P49803-1", "url": "", "sequence": { "sequence": "MAQGNNYGQTSNGVAEESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELHRQIKYWQIQLDRHRLKMSKVADSLLSYTEQYVEYDPFLVPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIREVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKRKGRNIPIFPCHKNCTPTLRASTNLL", "length": 477, "header": "sp|P49803-1|RGS7_RAT Isoform 1 of Regulator of G-protein signaling 7 OS=Rattus norvegicus OX=10116 GN=Rgs7 PE=1 SV=2 CANONICAL=P49803-1" }, "locus": { "chromosome": "13", "start_pos": 87407429, "end_pos": 86996636, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000116817", "url": "https://www.ensembl.org/id/ENSRNOT00000116817" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000082844", "url": "https://www.ensembl.org/id/ENSRNOP00000082844" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 229, "end_pos": 229, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P49803", "url": "https://www.uniprot.org/uniprot/P49803" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "P49803", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49803" } ], "site_lbl": "Ser229" }, { "start_pos": 241, "end_pos": 241, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P49803", "url": "https://www.uniprot.org/uniprot/P49803" } ], "site_lbl": "Ser241" }, { "start_pos": 243, "end_pos": 243, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P49803", "url": "https://www.uniprot.org/uniprot/P49803" } ], "site_lbl": "Thr243" }, { "start_pos": 434, "end_pos": 434, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P49803", "url": "https://www.uniprot.org/uniprot/P49803" } ], "site_lbl": "Ser434" } ], "glycation": [], "keywords": [], "publication": [ { "title": "RGS7 and RGS8 differentially accelerate G protein-mediated modulation of K+ currents.", "journal": "J. Biol. Chem.", "date": "1999", "authors": "Saitoh O, Kubo Y, Odagiri M, Ichikawa M, Yamagata K, Sekine T", "evidence": [ { "database": "UniProtKB", "id": "P49803", "url": "https://www.uniprot.org/uniprot/P49803" } ], "reference": [ { "type": "PubMed", "id": "10092682", "url": "https://glygen.org/publication/PubMed/10092682" } ] }, { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nature communications", "date": "2012", "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV", "evidence": [ { "database": "UniProtKB", "id": "P49803", "url": "https://www.uniprot.org/uniprot/P49803" }, { "database": "UniProtKB", "id": "D3ZWG2", "url": "https://www.uniprot.org/uniprot/D3ZWG2" }, { "database": "iPTMnet", "id": "P49803", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P49803" } ], "reference": [ { "type": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] }, { "title": "EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins.", "journal": "Cell", "date": "1996", "authors": "Koelle MR, Horvitz HR", "evidence": [ { "database": "UniProtKB", "id": "P49803", "url": "https://www.uniprot.org/uniprot/P49803" } ], "reference": [ { "type": "PubMed", "id": "8548815", "url": "https://glygen.org/publication/PubMed/8548815" } ] }, { "title": "Regulators of G-protein signaling (RGS) proteins: region-specific expression of nine subtypes in rat brain.", "journal": "J. Neurosci.", "date": "1997", "authors": "Dohlman H.G., Nestler E.J., Gold S.J., Ni Y.G.", "evidence": [ { "database": "UniProtKB", "id": "P49803", "url": "https://www.uniprot.org/uniprot/P49803" } ], "reference": [ { "type": "PubMed", "id": "9315921", "url": "https://glygen.org/publication/PubMed/9315921" } ] } ], "pathway": [ { "id": "rno:54296", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:54296", "resource": "KEGG Pathway" }, { "id": "R-RNO-418594", "name": "G alpha (i) signalling events", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" }, { "id": "R-RNO-6814122", "name": "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6814122", "resource": "Reactome", "description": "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" } ], "orthologs": [ { "uniprot_canonical_ac": 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