{
    "uniprot_canonical_ac": "P48164-1",
    "uniprot_ac": "P48164",
    "uniprot_id": "RS7B_YEAST",
    "mass": {
        "chemical_mass": 21634.0,
        "monoisotopic_mass": 21634.0
    },
    "refseq": {
        "ac": "NP_014303",
        "name": "ribosomal 40S subunit protein S7B",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014303"
    },
    "gene_names": [
        {
            "name": "RPS7B",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/P48164",
            "id": "P48164"
        },
        {
            "name": "N2212",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/P48164",
            "id": "P48164"
        },
        {
            "name": "RPS7B",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014303",
            "id": "NP_014303"
        }
    ],
    "protein_names": [
        {
            "name": "Small ribosomal subunit protein eS7B",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "P48164"
        },
        {
            "name": "40S ribosomal protein S7-B",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P48164"
        },
        {
            "name": "ribosomal 40S subunit protein S7B",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014303",
            "id": "NP_014303"
        }
    ],
    "function": [
        {
            "annotation": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102). eS7 is involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (PubMed:15590835).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P48164",
                    "url": "https://www.uniprot.org/uniprot/P48164#function"
                },
                {
                    "database": "PubMed",
                    "id": "15590835",
                    "url": "https://glygen.org/publication/PubMed/15590835"
                },
                {
                    "database": "PubMed",
                    "id": "22096102",
                    "url": "https://glygen.org/publication/PubMed/22096102"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0111881",
            "recommended_name": {
                "id": "DOID:0111881",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0111881",
                "name": "Diamond-Blackfan anemia 8",
                "description": "A Diamond-Blackfan anemia that has_material_basis_in heterozygous mutation in the RPS7 gene on chromosome 2p25.3."
            },
            "synonyms": [
                {
                    "id": "DOID:0111881",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111881",
                    "name": "DBA8",
                    "description": ""
                },
                {
                    "id": "DOID:0111881",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111881",
                    "name": "RPS7-related Diamond-Blackfan anemia",
                    "description": ""
                },
                {
                    "id": "MONDO:0012939",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012939",
                    "name": "Diamond-Blackfan anemia 8",
                    "description": "Any Diamond-Blackfan anemia in which the cause of the disease is a mutation in the RPS7 gene."
                },
                {
                    "id": "MONDO:0012939",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012939",
                    "name": "Diamond-Blackfan Anaemia type 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0012939",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012939",
                    "name": "Diamond-Blackfan Anemia type 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0012939",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012939",
                    "name": "Diamond-Blackfan anaemia caused by mutation in RPS7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012939",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012939",
                    "name": "Diamond-Blackfan anemia 8",
                    "description": ""
                },
                {
                    "id": "MONDO:0012939",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012939",
                    "name": "Diamond-Blackfan anemia caused by mutation in RPS7",
                    "description": ""
                },
                {
                    "id": "MONDO:0012939",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012939",
                    "name": "RPS7 Diamond-Blackfan anaemia",
                    "description": ""
                },
                {
                    "id": "MONDO:0012939",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012939",
                    "name": "RPS7 Diamond-Blackfan anemia",
                    "description": ""
                },
                {
                    "id": "MONDO:0012939",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012939",
                    "name": "DBA8",
                    "description": ""
                },
                {
                    "id": "MIM:612563",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/612563",
                    "name": "Diamond-Blackfan anemia 8",
                    "description": "Diamond-Blackfan anemia 8"
                }
            ],
            "evidence": [
                {
                    "id": "0111881",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111881"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Saccharomyces cerevisiae S288C",
            "taxid": 559292,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P48164",
                    "url": "https://www.uniprot.org/uniprot/P48164"
                }
            ],
            "common_name": "Yeast"
        }
    ],
    "gene": [
        {
            "name": "RPS7B",
            "url": "https://www.uniprot.org/uniprot/P48164",
            "locus": {}
        }
    ],
    "crossref": [
        {
            "id": "855628",
            "url": "https://www.ncbi.nlm.nih.gov/gene/855628",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "P48164",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:P48164*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR000554",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000554",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "sce:YNL096C",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YNL096C",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "HTKKVGQ",
            "url": "https://omabrowser.org/oma/group/HTKKVGQ/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5473994at2759",
            "url": "http://www.orthodb.org/?query=5473994at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11278",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11278",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11278:SF0",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11278:SF0",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF01251",
            "url": "http://pfam.xfam.org/family/PF01251",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_P48164",
            "url": "http://purl.obolibrary.org/obo/PR_P48164",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_014303",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014303",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "S000005040",
            "url": "https://www.yeastgenome.org/locus/S000005040",
            "database": "SGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "P48164",
            "url": "https://www.uniprot.org/uniprot/P48164",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P48164-1",
            "url": "https://www.uniprot.org/uniprot/P48164-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
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        "sequence": "MSSVQSKILSQAPSELELQVAKTFIDLESSSPELKADLRPLQIKSIREIDVTGGKKALVLFVPVPALSAYHKVQTKLTRELEKKFPDRHVIFLAERRILPKPSRTSRQVQKRPRSRTLTAVHDKVLEDMVFPTEIVGKRVRYLVGGNKIQKVLLDSKDVQQIDYKLESFQAVYNKLTGKQIVFEIPSQTN",
        "length": 190,
        "header": "sp|P48164-1|RS7B_YEAST Isoform 1 of Small ribosomal subunit protein eS7B  OS=Saccharomyces cerevisiae S288C OX=559292 GN=RPS7B PE=1 SV=1 CANONICAL=P48164-1"
    },
    "isoforms": [
        {
            "isoform_ac": "P48164-1",
            "url": "",
            "sequence": {
                "sequence": "MSSVQSKILSQAPSELELQVAKTFIDLESSSPELKADLRPLQIKSIREIDVTGGKKALVLFVPVPALSAYHKVQTKLTRELEKKFPDRHVIFLAERRILPKPSRTSRQVQKRPRSRTLTAVHDKVLEDMVFPTEIVGKRVRYLVGGNKIQKVLLDSKDVQQIDYKLESFQAVYNKLTGKQIVFEIPSQTN",
                "length": 190,
                "header": "sp|P48164-1|RS7B_YEAST Isoform 1 of Small ribosomal subunit protein eS7B  OS=Saccharomyces cerevisiae S288C OX=559292 GN=RPS7B PE=1 SV=1 CANONICAL=P48164-1"
            },
            "locus": {
                "chromosome": "XIV",
                "start_pos": 444315,
                "end_pos": 443401,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "YNL096C_mRNA",
                        "url": "https://www.ensembl.org/id/YNL096C_mRNA"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "YNL096C",
                        "url": "https://www.ensembl.org/id/YNL096C"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [
        {
            "start_pos": 10,
            "end_pos": 10,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P48164",
                    "url": "https://www.uniprot.org/uniprot/P48164"
                },
                {
                    "database": "PubMed",
                    "id": "18407956",
                    "url": "https://glygen.org/publication/PubMed/18407956"
                },
                {
                    "database": "PubMed",
                    "id": "19779198",
                    "url": "https://glygen.org/publication/PubMed/19779198"
                },
                {
                    "database": "iPTMnet",
                    "id": "P48164",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164"
                },
                {
                    "database": "PubMed",
                    "id": "21126336",
                    "url": "https://glygen.org/publication/PubMed/21126336"
                },
                {
                    "database": "SGD",
                    "id": "P48164",
                    "url": "https://www.yeastgenome.org/locus/P48164"
                }
            ],
            "site_lbl": "Ser10"
        },
        {
            "start_pos": 115,
            "end_pos": 115,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "P48164",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164"
                },
                {
                    "database": "PubMed",
                    "id": "17287358",
                    "url": "https://glygen.org/publication/PubMed/17287358"
                },
                {
                    "database": "PubMed",
                    "id": "18407956",
                    "url": "https://glygen.org/publication/PubMed/18407956"
                },
                {
                    "database": "PubMed",
                    "id": "20702584",
                    "url": "https://glygen.org/publication/PubMed/20702584"
                },
                {
                    "database": "PubMed",
                    "id": "21177495",
                    "url": "https://glygen.org/publication/PubMed/21177495"
                },
                {
                    "database": "SGD",
                    "id": "P48164",
                    "url": "https://www.yeastgenome.org/locus/P48164"
                }
            ],
            "site_lbl": "Ser115"
        },
        {
            "start_pos": 117,
            "end_pos": 117,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Thr",
            "comment": "",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "P48164",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164"
                },
                {
                    "database": "PubMed",
                    "id": "17287358",
                    "url": "https://glygen.org/publication/PubMed/17287358"
                },
                {
                    "database": "PubMed",
                    "id": "20702584",
                    "url": "https://glygen.org/publication/PubMed/20702584"
                },
                {
                    "database": "PubMed",
                    "id": "21177495",
                    "url": "https://glygen.org/publication/PubMed/21177495"
                },
                {
                    "database": "SGD",
                    "id": "P48164",
                    "url": "https://www.yeastgenome.org/locus/P48164"
                },
                {
                    "database": "PubMed",
                    "id": "23749301",
                    "url": "https://glygen.org/publication/PubMed/23749301"
                }
            ],
            "site_lbl": "Thr117"
        },
        {
            "start_pos": 119,
            "end_pos": 119,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Thr",
            "comment": "",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "P48164",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164"
                },
                {
                    "database": "PubMed",
                    "id": "18407956",
                    "url": "https://glygen.org/publication/PubMed/18407956"
                },
                {
                    "database": "PubMed",
                    "id": "19779198",
                    "url": "https://glygen.org/publication/PubMed/19779198"
                },
                {
                    "database": "PubMed",
                    "id": "21177495",
                    "url": "https://glygen.org/publication/PubMed/21177495"
                },
                {
                    "database": "SGD",
                    "id": "P48164",
                    "url": "https://www.yeastgenome.org/locus/P48164"
                },
                {
                    "database": "PubMed",
                    "id": "23749301",
                    "url": "https://glygen.org/publication/PubMed/23749301"
                }
            ],
            "site_lbl": "Thr119"
        },
        {
            "start_pos": 14,
            "end_pos": 14,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "P48164",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164"
                },
                {
                    "database": "PubMed",
                    "id": "18407956",
                    "url": "https://glygen.org/publication/PubMed/18407956"
                },
                {
                    "database": "PubMed",
                    "id": "19779198",
                    "url": "https://glygen.org/publication/PubMed/19779198"
                },
                {
                    "database": "SGD",
                    "id": "P48164",
                    "url": "https://www.yeastgenome.org/locus/P48164"
                }
            ],
            "site_lbl": "Ser14"
        },
        {
            "start_pos": 156,
            "end_pos": 156,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "P48164",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164"
                },
                {
                    "database": "PubMed",
                    "id": "18407956",
                    "url": "https://glygen.org/publication/PubMed/18407956"
                },
                {
                    "database": "SGD",
                    "id": "P48164",
                    "url": "https://www.yeastgenome.org/locus/P48164"
                },
                {
                    "database": "PubMed",
                    "id": "23749301",
                    "url": "https://glygen.org/publication/PubMed/23749301"
                }
            ],
            "site_lbl": "Ser156"
        },
        {
            "start_pos": 23,
            "end_pos": 23,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Thr",
            "comment": "",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "P48164",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164"
                },
                {
                    "database": "PubMed",
                    "id": "21126336",
                    "url": "https://glygen.org/publication/PubMed/21126336"
                }
            ],
            "site_lbl": "Thr23"
        },
        {
            "start_pos": 31,
            "end_pos": 31,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P48164",
                    "url": "https://www.uniprot.org/uniprot/P48164"
                },
                {
                    "database": "PubMed",
                    "id": "19779198",
                    "url": "https://glygen.org/publication/PubMed/19779198"
                },
                {
                    "database": "PubMed",
                    "id": "17330950",
                    "url": "https://glygen.org/publication/PubMed/17330950"
                },
                {
                    "database": "iPTMnet",
                    "id": "P48164",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164"
                },
                {
                    "database": "PubMed",
                    "id": "15665377",
                    "url": "https://glygen.org/publication/PubMed/15665377"
                },
                {
                    "database": "PubMed",
                    "id": "18407956",
                    "url": "https://glygen.org/publication/PubMed/18407956"
                },
                {
                    "database": "PubMed",
                    "id": "19795423",
                    "url": "https://glygen.org/publication/PubMed/19795423"
                },
                {
                    "database": "PubMed",
                    "id": "19823750",
                    "url": "https://glygen.org/publication/PubMed/19823750"
                },
                {
                    "database": "PubMed",
                    "id": "20702584",
                    "url": "https://glygen.org/publication/PubMed/20702584"
                },
                {
                    "database": "SGD",
                    "id": "P48164",
                    "url": "https://www.yeastgenome.org/locus/P48164"
                },
                {
                    "database": "PubMed",
                    "id": "23749301",
                    "url": "https://glygen.org/publication/PubMed/23749301"
                }
            ],
            "site_lbl": "Ser31"
        },
        {
            "start_pos": 75,
            "end_pos": 75,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Thr",
            "comment": "",
            "evidence": [
                {
                    "database": "SGD",
                    "id": "P48164",
                    "url": "https://www.yeastgenome.org/locus/P48164"
                },
                {
                    "database": "iPTMnet",
                    "id": "P48164",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P48164"
                },
                {
                    "database": "PubMed",
                    "id": "23749301",
                    "url": "https://glygen.org/publication/PubMed/23749301"
                }
            ],
            "site_lbl": "Thr75"
        }
    ],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "The action of N-terminal acetyltransferases on yeast ribosomal proteins.",
            "journal": "J. Biol. Chem.",
            "date": "1999",
            "authors": "Arnold R J, Polevoda B, Reilly J P, Sherman F",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P48164",
                    "url": "https://www.uniprot.org/uniprot/P48164"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "10601260",
                    "url": "https://glygen.org/publication/PubMed/10601260"
                }
            ]
        },
        {
            "title": "Global analysis of protein localization in budding yeast.",
            "journal": "Nature",
            "date": "2003",
            "authors": "Weissman J.S., Carroll A.S., Howson R.W., Huh W.-K., O'Shea E.K., Falvo J.V., Gerke L.C.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P48164",
                    "url": "https://www.uniprot.org/uniprot/P48164"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
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