{
    "uniprot_canonical_ac": "P45888-1",
    "uniprot_ac": "P45888",
    "uniprot_id": "ARP2_DROME",
    "mass": {
        "chemical_mass": 45282.0,
        "monoisotopic_mass": 45282.0
    },
    "refseq": {
        "ac": "NP_001097001",
        "name": "Actin-related protein 2, isoform B",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097001"
    },
    "gene_names": [
        {
            "name": "Arp2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/P45888",
            "id": "P45888"
        },
        {
            "name": "Actr14D; Arp14D; ARP14D; arp2; ARP2; CG9901; Dmel\\CG9901",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097001",
            "id": "NP_001097001"
        },
        {
            "name": "Actr14D",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/P45888",
            "id": "P45888"
        },
        {
            "name": "Arp14D",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/P45888",
            "id": "P45888"
        },
        {
            "name": "Arp2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097001",
            "id": "NP_001097001"
        },
        {
            "name": "CG9901",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/P45888",
            "id": "P45888"
        }
    ],
    "protein_names": [
        {
            "name": "Actin-related protein 2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "P45888"
        },
        {
            "name": "Actin-like protein 14D",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P45888"
        },
        {
            "name": "Actin-like protein 2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P45888"
        },
        {
            "name": "Actin-related protein 2, isoform B",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097001",
            "id": "NP_001097001"
        },
        {
            "name": "CG9901-PB; Arp2-PB; Actin-related protein 14D; Actin-related protein 14 Da; Arp14D",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097001",
            "id": "NP_001097001"
        }
    ],
    "function": [
        {
            "annotation": "Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P45888",
                    "url": "https://www.uniprot.org/uniprot/P45888#function"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0080199",
            "recommended_name": {
                "id": "DOID:0080199",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0080199",
                "name": "colorectal carcinoma",
                "description": "A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "0080199",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080199"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Drosophila melanogaster",
            "taxid": 7227,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P45888",
                    "url": "https://www.uniprot.org/uniprot/P45888"
                }
            ],
            "common_name": "Fruit fly"
        }
    ],
    "gene": [
        {
            "name": "Arp2",
            "url": "https://www.uniprot.org/uniprot/P45888",
            "locus": {
                "chromosome": "X",
                "start_pos": 16548290,
                "end_pos": 16553968,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "FBgn0011742",
                        "url": "https://www.ensembl.org/id/FBgn0011742"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "FBgn0011742",
            "url": "https://bgee.org/?page=gene&gene_id=FBgn0011742",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd00012",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00012",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "FBgn0011742",
            "url": "https://flybase.org/reports/FBgn0011742",
            "database": "FlyBase",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "32623",
            "url": "https://www.ncbi.nlm.nih.gov/gene/32623",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR004000",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR004000",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR020902",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR020902",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR043129",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dme:Dmel_CG9901",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG9901",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "WEDMQHL",
            "url": "https://omabrowser.org/oma/group/WEDMQHL/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "176764at2759",
            "url": "http://www.orthodb.org/?query=176764at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11937",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11937",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11937:SF37",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11937:SF37",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00022",
            "url": "http://pfam.xfam.org/family/PF00022",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_P45888",
            "url": "http://purl.obolibrary.org/obo/PR_P45888",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-DME-2029482",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2029482",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-3928662",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-3928662",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-5663213",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5663213",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-6798695",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798695",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-8856828",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8856828",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001097001",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097001",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P45888",
            "url": "https://www.uniprot.org/uniprot/P45888",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P45888-1",
            "url": "https://www.uniprot.org/uniprot/P45888-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P45888-2",
            "url": "https://www.uniprot.org/uniprot/P45888-2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MDSKGRNVIVCDNGTGFVKCGYAGSNFPTHIFPSMVGRPMIRAVNKIGDIEVKDLHVDDLMVGDEASQLRSLLEVSYPMENGVVRNWDDMCHVWDYTFGPKKMDIDPTNTKILLTEPPMNPTKNREKMIEVMFEKYGFDSAYIAIQAVLTLYAQGLISGVVIDSGDGVTHICPVYEEFALPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRIMKEKLCYIGYDIEMEQRLALETTVLVESYTLPDGRVIKVGGERFEAPEALFQPHLINVEGPGIAELAFNTIQAADIDIRPELYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKDRDGFWMSKQEYQEQGLKVLQKLQKISH",
        "length": 399,
        "header": "sp|P45888-1|ARP2_DROME Isoform 1 of Actin-related protein 2  OS=Drosophila melanogaster OX=7227 GN=Arp2 PE=2 SV=3 CANONICAL=P45888-1"
    },
    "isoforms": [
        {
            "isoform_ac": "P45888-1",
            "url": "",
            "sequence": {
                "sequence": "MDSKGRNVIVCDNGTGFVKCGYAGSNFPTHIFPSMVGRPMIRAVNKIGDIEVKDLHVDDLMVGDEASQLRSLLEVSYPMENGVVRNWDDMCHVWDYTFGPKKMDIDPTNTKILLTEPPMNPTKNREKMIEVMFEKYGFDSAYIAIQAVLTLYAQGLISGVVIDSGDGVTHICPVYEEFALPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRIMKEKLCYIGYDIEMEQRLALETTVLVESYTLPDGRVIKVGGERFEAPEALFQPHLINVEGPGIAELAFNTIQAADIDIRPELYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKDRDGFWMSKQEYQEQGLKVLQKLQKISH",
                "length": 399,
                "header": "sp|P45888-1|ARP2_DROME Isoform 1 of Actin-related protein 2  OS=Drosophila melanogaster OX=7227 GN=Arp2 PE=2 SV=3 CANONICAL=P45888-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 16553391,
                "end_pos": 16549245,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0310673",
                        "url": "https://www.ensembl.org/id/FBtr0310673"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0302793",
                        "url": "https://www.ensembl.org/id/FBpp0302793"
                    }
                ]
            }
        },
        {
            "isoform_ac": "P45888-2",
            "url": "",
            "sequence": {
                "sequence": "MDSKGRNVIVCDNGTGFVKCGYAGSNFPTHIFPSMVGRPMIRAVNKIGDIEVKDLMVGDEASQLRSLLEVSYPMENGVVRNWDDMCHVWDYTFGPKKMDIDPTNTKILLTEPPMNPTKNREKMIEVMFEKYGFDSAYIAIQAVLTLYAQGLISGVVIDSGDGVTHICPVYEEFALPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRIMKEKLCYIGYDIEMEQRLALETTVLVESYTLPDGRVIKVGGERFEAPEALFQPHLINVEGPGIAELAFNTIQAADIDIRPELYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKDRDGFWMSKQEYQEQGLKVLQKLQKISH",
                "length": 394,
                "header": "sp|P45888-2|ARP2_DROME Isoform 2 of Actin-related protein 2  OS=Drosophila melanogaster OX=7227 GN=Arp2 PE=2 SV=3 CANONICAL=P45888-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 16553391,
                "end_pos": 16549245,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0112868",
                        "url": "https://www.ensembl.org/id/FBtr0112868"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0111781",
                        "url": "https://www.ensembl.org/id/FBpp0111781"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "The genome sequence of Drosophila melanogaster.",
            "journal": "Science",
            "date": "2000",
            "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P45888",
                    "url": "https://www.uniprot.org/uniprot/P45888"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "10731132",
                    "url": "https://glygen.org/publication/PubMed/10731132"
                }
            ]
        },
        {
            "title": "A Drosophila full-length cDNA resource.",
            "journal": "Genome Biol.",
            "date": "2002",
            "authors": "Stapleton M, Carlson J, Brokstein P, Yu C, Champe M, George R, Guarin H, Kronmiller B, Pacleb J, Park S, Wan K, Rubin GM, Celniker SE",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P45888",
                    "url": "https://www.uniprot.org/uniprot/P45888"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12537569",
                    "url": "https://glygen.org/publication/PubMed/12537569"
                }
            ]
        },
        {
            "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.",
            "journal": "Genome Biol.",
            "date": "2002",
            "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P45888",
                    "url": "https://www.uniprot.org/uniprot/P45888"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12537572",
                    "url": "https://glygen.org/publication/PubMed/12537572"
                }
            ]
        },
        {
            "title": "Genes encoding actin-related proteins of Drosophila melanogaster.",
            "journal": "J. Mol. Biol.",
            "date": "1994",
            "authors": "Fyrberg C., Fyrberg E.A., Kenton M., Ryan L.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P45888",
                    "url": "https://www.uniprot.org/uniprot/P45888"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "8064864",
                    "url": "https://glygen.org/publication/PubMed/8064864"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "dme:Dmel_CG9901",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG9901",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-DME-2029482",
            "name": "Regulation of actin dynamics for phagocytic cup formation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2029482",
            "resource": "Reactome",
            "description": "Regulation of actin dynamics for phagocytic cup formation"
        },
        {
            "id": "R-DME-3928662",
            "name": "EPHB-mediated forward signaling",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-3928662",
            "resource": "Reactome",
            "description": "EPHB-mediated forward signaling"
        },
        {
            "id": "R-DME-5663213",
            "name": "RHO GTPases Activate WASPs and WAVEs",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5663213",
            "resource": "Reactome",
            "description": "RHO GTPases Activate WASPs and WAVEs"
        },
        {
            "id": "R-DME-6798695",
            "name": "Neutrophil degranulation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798695",
            "resource": "Reactome",
            "description": "Neutrophil degranulation"
        },
        {
            "id": "R-DME-8856828",
            "name": "Clathrin-mediated endocytosis",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8856828",
            "resource": "Reactome",
            "description": "Clathrin-mediated endocytosis"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "P32381-1",
            "protein_name": "Actin-related protein 2",
            "gene_name": "ARP2",
            "tax_id": 559292,
            "organism": "Saccharomyces cerevisiae S288C",
            "sequence": {
                "sequence": "MDPHNPIVLDQGTGFVKIGRAGENFPDYTFPSIVGRPILRAEERASVATPLKDIMIGDEASEVRSYLQISYPMENGIIKNWTDMELLWDYAFFEQMKLPSTSNGKILLTEPPMNPLKNREKMCEVMFEKYDFGGVYVAIQAVLALYAQGLSSGVVVDSGDGVTHIVPVYESVVLSHLTRRLDVAGRDVTRHLIDLLSRRGYAFNRTADFETVRQIKEKLCYVSYDLDLDTKLARETTALVESYELPDGRTIKVGQERFEAPECLFQPGLVDVEQPGVGELLFNTVQSADVDIRSSLYKAIVLSGGSSMYPGLPSRLEKELKQLWFSRVLHNDPSRLDKFKVRIEDPPRRKHMVFIGGAVLASIMADKDHMWLSKQEWQESGPSAMTKFGPR",
                "length": 391
            },
            "evidence": [
                {
                    "id": "P45888",
                    "url": "https://omabrowser.org/oma/group/P45888/",
                    "database": "OMA"
                }
            ],
            "common_name": "Yeast"
        },
        {
            "uniprot_canonical_ac": "P61160-1",
            "protein_name": "Actin-related protein 2",
            "gene_name": "ACTR2",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKDLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR",
                "length": 394
            },
            "evidence": [
                {
                    "id": "P45888",
                    "url": "https://omabrowser.org/oma/group/P45888/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P61161-1",
            "protein_name": "Actin-related protein 2",
            "gene_name": "Actr2",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKDLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR",
                "length": 394
            },
            "evidence": [
                {
                    "id": "P45888",
                    "url": "https://omabrowser.org/oma/group/P45888/",
                    "database": "OMA"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 6,
                "go_terms": [
                    {
                        "name": "terminal button organization",
                        "id": "GO:0072553",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072553",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P45888",
                                "url": "https://www.uniprot.org/uniprot/P45888"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "actin filament organization",
                        "id": "GO:0007015",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015",
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                            {
                                "database": "UniProtKB",
                                "id": "P45888",
                                "url": "https://www.uniprot.org/uniprot/P45888"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell morphogenesis",
                        "id": "GO:0000902",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P45888",
                                "url": "https://www.uniprot.org/uniprot/P45888"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "Arp2/3 complex-mediated actin nucleation",
                        "id": "GO:0034314",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034314",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P45888",
                                "url": "https://www.uniprot.org/uniprot/P45888"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of synaptic assembly at neuromuscular junction",
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045887",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P45888",
                                "url": "https://www.uniprot.org/uniprot/P45888"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of filopodium assembly",
                        "id": "GO:0051489",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051489",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P45888",
                                "url": "https://www.uniprot.org/uniprot/P45888"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 3,
                "go_terms": [
                    {
                        "name": "actin binding",
                        "id": "GO:0003779",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P45888",
                                "url": "https://www.uniprot.org/uniprot/P45888"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "structural constituent of cytoskeleton",
                        "id": "GO:0005200",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P45888",
                                "url": "https://www.uniprot.org/uniprot/P45888"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ATP binding",
                        "id": "GO:0005524",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P45888",
                                "url": "https://www.uniprot.org/uniprot/P45888"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 3,
                "go_terms": [
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P45888",
                                "url": "https://www.uniprot.org/uniprot/P45888"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "actin filament",
                        "id": "GO:0005884",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P45888",
                                "url": "https://www.uniprot.org/uniprot/P45888"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "Arp2/3 protein complex",
                        "id": "GO:0005885",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005885",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P45888",
                                "url": "https://www.uniprot.org/uniprot/P45888"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 13,
            "end_pos": 15,
            "annotation": "n_glycosylation_sequon"
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            "annotation": "n_glycosylation_sequon"
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            "end_pos": 339,
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    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
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