{ "uniprot_canonical_ac": "P41811-1", "uniprot_ac": "P41811", "uniprot_id": "COPB2_YEAST", "mass": { "chemical_mass": 99445.0, "monoisotopic_mass": 99445.0 }, "refseq": { "ac": "NP_011378", "name": "coatomer subunit beta'", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011378" }, "gene_names": [ { "name": "SEC27", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P41811", "id": "P41811" }, { "name": "G2827", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/P41811", "id": "P41811" }, { "name": "SEC27", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011378", "id": "NP_011378" } ], "protein_names": [ { "name": "Coatomer subunit beta'", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P41811" }, { "name": "Beta'-COP", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P41811" }, { "name": "Beta'-coat protein", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P41811" }, { "name": "coatomer subunit beta'", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011378", "id": "NP_011378" } ], "function": [ { "annotation": "The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.", "evidence": [ { "database": "UniProtKB", "id": "P41811", "url": "https://www.uniprot.org/uniprot/P41811#function" }, { "database": "PubMed", "id": "17101773", "url": "https://glygen.org/publication/PubMed/17101773" } ] } ], "disease": [ { "disease_id": "DOID:0070281", "recommended_name": { "id": "DOID:0070281", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0070281", "name": "primary autosomal recessive microcephaly 19", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous or compound heterozygous mutation in the COPB2 gene on chromosome 3q23." }, "synonyms": [ { "id": "DOID:0070281", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0070281", "name": "MCPH19", "description": "" }, { "id": "MONDO:0054716", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0054716", "name": "microcephaly 19, primary, autosomal recessive", "description": "" }, { "id": "MONDO:0054716", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0054716", "name": "MCPH19", "description": "" }, { "id": "MONDO:0054716", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0054716", "name": "microcephaly 19, PRIMARY, autosomal recessive", "description": "" }, { "id": "MONDO:0054716", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0054716", "name": "primary autosomal recessive microcephaly 19", "description": "" }, { "id": "MIM:617800", "resource": "MIM", "url": "https://www.omim.org/entry/617800", "name": "Microcephaly 19, primary, autosomal recessive", "description": "Microcephaly 19, primary, autosomal recessive" } ], "evidence": [ { "id": "0070281", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0070281" } ] }, { "disease_id": "DOID:10907", "recommended_name": { "id": "DOID:10907", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10907", "name": "microcephaly", "description": "A congenital nervous system abnormality that is characterized by a significantly smaller than normal head in infants." }, "synonyms": [ { "id": "DOID:10907", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10907", "name": "Microcephalus", "description": "" }, { "id": "DOID:10907", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10907", "name": "microencephaly", "description": "" } ], "evidence": [ { "id": "10907", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:10907" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P41811", "url": "https://www.uniprot.org/uniprot/P41811" } ], "common_name": "Yeast" } ], "gene": [ { "name": "SEC27", "url": "https://www.uniprot.org/uniprot/P41811", "locus": {} } ], "crossref": [ { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22938", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22938", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "852740", "url": "https://www.ncbi.nlm.nih.gov/gene/852740", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "P41811", "url": "https://www.ebi.ac.uk/intact/interactors/id:P41811*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006692", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006692", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "sce:YGL137W", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YGL137W", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NVFWNES", "url": "https://omabrowser.org/oma/group/NVFWNES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "20819at2759", "url": "http://www.orthodb.org/?query=20819at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19876", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19876", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19876:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19876:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "2YNN", "url": "https://www.rcsb.org/structure/2YNN", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "2YNO", "url": "https://www.rcsb.org/structure/2YNO", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "2YNP", "url": "https://www.rcsb.org/structure/2YNP", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "4J73", "url": "https://www.rcsb.org/structure/4J73", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "4J77", "url": "https://www.rcsb.org/structure/4J77", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "4J78", "url": "https://www.rcsb.org/structure/4J78", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "4J79", "url": "https://www.rcsb.org/structure/4J79", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "4J81", "url": "https://www.rcsb.org/structure/4J81", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "4J82", "url": "https://www.rcsb.org/structure/4J82", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "4J84", "url": "https://www.rcsb.org/structure/4J84", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "4J86", "url": "https://www.rcsb.org/structure/4J86", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00400", "url": "http://pfam.xfam.org/family/PF00400", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF04053", "url": "http://pfam.xfam.org/family/PF04053", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_P41811", "url": "http://purl.obolibrary.org/obo/PR_P41811", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_011378", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011378", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "S000003105", "url": "https://www.yeastgenome.org/locus/S000003105", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P41811", "url": "https://www.uniprot.org/uniprot/P41811", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P41811-1", "url": "https://www.uniprot.org/uniprot/P41811-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLDIKKTFSNRSDRVKGIDFHPTEPWVLTTLYSGRVELWNYETQVEVRSIQVTETPVRAGKFIARKNWIIVGSDDFRIRVFNYNTGEKVVDFEAHPDYIRSIAVHPTKPYVLSGSDDLTVKLWNWENNWALEQTFEGHEHFVMCVAFNPKDPSTFASGCLDRTVKVWSLGQSTPNFTLTTGQERGVNYVDYYPLPDKPYMITASDDLTIKIWDYQTKSCVATLEGHMSNVSFAVFHPTLPIIISGSEDGTLKIWNSSTYKVEKTLNVGLERSWCIATHPTGRKNYIASGFDNGFTVLSLGNDEPTLSLDPVGKLVWSGGKNAAASDIFTAVIRGNEEVEQDEPLSLQTKELGSVDVFPQSLAHSPNGRFVTVVGDGEYVIYTALAWRNKAFGKCQDFVWGPDSNSYALIDETGQIKYYKNFKEVTSWSVPMHSAIDRLFSGALLGVKSDGFVYFFDWDNGTLVRRIDVNAKDVIWSDNGELVMIVNTNSNGDEASGYTLLFNKDAYLEAANNGNIDDSEGVDEAFDVLYELSESITSGKWVGDVFIFTTATNRLNYFVGGKTYNLAHYTKEMYLLGYLARDNKVYLADREVHVYGYEISLEVLEFQTLTLRGEIEEAIENVLPNVEGKDSLTKIARFLEGQEYYEEALNISPDQDQKFELALKVGQLTLARDLLTDESAEMKWRALGDASLQRFNFKLAVEAFTNAHDLESLFLLHSSFNNKEGLVTLAKDAERAGKFNLAFNAYWIAGDIQGAKDLLIKSQRFSEAAFLGSTYGLGDDAVNDIVTKWKENLILNGKNTVSERVCGAEGLPGSSSSGDAQPLIDLDSTPAPEQADENKEAEVEDSEFKESNSEAVEAEKKEEEAPQQQQSEQQPEQGEAVPEPVEEES", "length": 889, "header": "sp|P41811-1|COPB2_YEAST Isoform 1 of Coatomer subunit beta' OS=Saccharomyces cerevisiae S288C OX=559292 GN=SEC27 PE=1 SV=1 CANONICAL=P41811-1" }, "isoforms": [ { "isoform_ac": "P41811-1", "url": "", "sequence": { "sequence": "MKLDIKKTFSNRSDRVKGIDFHPTEPWVLTTLYSGRVELWNYETQVEVRSIQVTETPVRAGKFIARKNWIIVGSDDFRIRVFNYNTGEKVVDFEAHPDYIRSIAVHPTKPYVLSGSDDLTVKLWNWENNWALEQTFEGHEHFVMCVAFNPKDPSTFASGCLDRTVKVWSLGQSTPNFTLTTGQERGVNYVDYYPLPDKPYMITASDDLTIKIWDYQTKSCVATLEGHMSNVSFAVFHPTLPIIISGSEDGTLKIWNSSTYKVEKTLNVGLERSWCIATHPTGRKNYIASGFDNGFTVLSLGNDEPTLSLDPVGKLVWSGGKNAAASDIFTAVIRGNEEVEQDEPLSLQTKELGSVDVFPQSLAHSPNGRFVTVVGDGEYVIYTALAWRNKAFGKCQDFVWGPDSNSYALIDETGQIKYYKNFKEVTSWSVPMHSAIDRLFSGALLGVKSDGFVYFFDWDNGTLVRRIDVNAKDVIWSDNGELVMIVNTNSNGDEASGYTLLFNKDAYLEAANNGNIDDSEGVDEAFDVLYELSESITSGKWVGDVFIFTTATNRLNYFVGGKTYNLAHYTKEMYLLGYLARDNKVYLADREVHVYGYEISLEVLEFQTLTLRGEIEEAIENVLPNVEGKDSLTKIARFLEGQEYYEEALNISPDQDQKFELALKVGQLTLARDLLTDESAEMKWRALGDASLQRFNFKLAVEAFTNAHDLESLFLLHSSFNNKEGLVTLAKDAERAGKFNLAFNAYWIAGDIQGAKDLLIKSQRFSEAAFLGSTYGLGDDAVNDIVTKWKENLILNGKNTVSERVCGAEGLPGSSSSGDAQPLIDLDSTPAPEQADENKEAEVEDSEFKESNSEAVEAEKKEEEAPQQQQSEQQPEQGEAVPEPVEEES", "length": 889, "header": "sp|P41811-1|COPB2_YEAST Isoform 1 of Coatomer subunit beta' OS=Saccharomyces cerevisiae S288C OX=559292 GN=SEC27 PE=1 SV=1 CANONICAL=P41811-1" }, "locus": { "chromosome": "VII", "start_pos": 252735, "end_pos": 249869, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "YGL137W_mRNA", "url": "https://www.ensembl.org/id/YGL137W_mRNA" }, { "database": "Ensembl Peptide", "id": "YGL137W", "url": "https://www.ensembl.org/id/YGL137W" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 326, "end_pos": 326, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P41811", "url": "https://www.uniprot.org/uniprot/P41811" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "P41811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41811" }, { "database": "SGD", "id": "P41811", "url": "https://www.yeastgenome.org/locus/P41811" } ], "site_lbl": "Ser326" }, { "start_pos": 346, "end_pos": 346, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P41811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41811" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ], "site_lbl": "Ser346" }, { "start_pos": 354, "end_pos": 354, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "P41811", "url": "https://www.yeastgenome.org/locus/P41811" }, { "database": "iPTMnet", "id": "P41811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41811" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser354" }, { "start_pos": 669, "end_pos": 669, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P41811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41811" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "P41811", "url": "https://www.yeastgenome.org/locus/P41811" } ], "site_lbl": "Thr669" }, { "start_pos": 829, "end_pos": 829, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P41811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41811" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "P41811", "url": "https://www.yeastgenome.org/locus/P41811" } ], "site_lbl": "Thr829" }, { "start_pos": 846, "end_pos": 846, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P41811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41811" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ], "site_lbl": "Ser846" }, { "start_pos": 851, "end_pos": 851, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P41811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41811" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ], "site_lbl": "Ser851" } ], "glycation": [], "keywords": [], "publication": [ { "title": "Global analysis of protein localization in budding yeast.", "journal": "Nature", "date": "2003", "authors": "Weissman J.S., Carroll A.S., Howson R.W., Huh W.-K., O'Shea E.K., Falvo J.V., Gerke L.C.", "evidence": [ { "database": "UniProtKB", "id": "P41811", "url": "https://www.uniprot.org/uniprot/P41811" } ], "reference": [ { "type": "PubMed", "id": "14562095", "url": "https://glygen.org/publication/PubMed/14562095" } ] }, { "title": "Global analysis of protein expression in yeast.", "journal": "Nature", "date": "2003", "authors": "Dephoure N., Weissman J.S., Howson R.W., Huh W.-K., O'Shea E.K., Belle A., Bower K., Ghaemmaghami S.", "evidence": [ { "database": "UniProtKB", "id": "P41811", "url": "https://www.uniprot.org/uniprot/P41811" } ], "reference": [ { "type": "PubMed", "id": "14562106", "url": "https://glygen.org/publication/PubMed/14562106" } ] }, { "title": "Involvement of specific COPI subunits in protein sorting from the late endosome to the vacuole in yeast.", "journal": "Mol. Cell. Biol.", "date": "2007", "authors": "Gerst J.E., Gabriely G., Kama R.", "evidence": [ { "database": "UniProtKB", "id": "P41811", "url": "https://www.uniprot.org/uniprot/P41811" } ], "reference": [ { "type": "PubMed", "id": "17101773", "url": "https://glygen.org/publication/PubMed/17101773" } ] }, { "title": "A multidimensional chromatography technology for in-depth phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P41811", "url": "https://www.uniprot.org/uniprot/P41811" }, { "database": "iPTMnet", "id": "P41811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41811" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.", "journal": "Science (New York, N.Y.)", "date": "2009-09-25", "authors": "Holt Liam J, Tuch Brian B, Vill\u00e9n Judit, Johnson Alexander D, Gygi Steven P, Morgan David O", "evidence": [ { "database": "UniProtKB", "id": "P41811", "url": "https://www.uniprot.org/uniprot/P41811" }, { "database": "iPTMnet", "id": "P41811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41811" } ], "reference": [ { "type": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" } ] }, { "title": "Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.", "journal": "BMC genomics", "date": "2010-12-02", "authors": "Helbig Andreas O, Rosati Sara, Pijnappel Pim W W M, van Breukelen Bas, Timmers Marc H T H, Mohammed Shabaz, Slijper Monique, Heck Albert J R", "evidence": [ { "database": "iPTMnet", "id": "P41811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41811" } ], "reference": [ { "type": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ] }, { "title": "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2012", "authors": "Van Damme P, Lasa M, Polevoda B, Gazquez C, Elosegui-Artola A, Kim DS, De Juan-Pardo E, Demeyer K, Hole K, Larrea E, Timmerman E, Prieto J, Arnesen T, Sherman F, Gevaert K, Aldabe R", "evidence": [ { "database": "UniProtKB", "id": "P41811", "url": "https://www.uniprot.org/uniprot/P41811" } ], "reference": [ { "type": "PubMed", "id": "22814378", "url": "https://glygen.org/publication/PubMed/22814378" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P41811", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P41811" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.", "journal": "G3 (Bethesda)", "date": "2014", "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael", "evidence": [ { "database": "UniProtKB", "id": "P41811", "url": "https://www.uniprot.org/uniprot/P41811" } ], "reference": [ { "type": "PubMed", "id": "24374639", "url": "https://glygen.org/publication/PubMed/24374639" } ] }, { "title": "Yeast beta- and beta'-coat proteins (COP). Two coatomer subunits essential for endoplasmic reticulum-to-Golgi protein traffic.", "journal": "J. Biol. Chem.", "date": "1994", "authors": "Duden R., Winey M., Schekman R., Hamamoto S., Byers B., Hosobuchi M.", "evidence": [ { "database": "UniProtKB", "id": "P41811", "url": "https://www.uniprot.org/uniprot/P41811" } ], "reference": [ { "type": "PubMed", "id": "7929113", "url": "https://glygen.org/publication/PubMed/7929113" } ] }, { "title": "Yeast coatomer contains a subunit homologous to mammalian beta'-COP.", "journal": "FEBS Lett.", "date": "1993", "authors": "Lottspeich F., Wieland F.T., Harter C., Draken E.", "evidence": [ { "database": "UniProtKB", "id": "P41811", "url": "https://www.uniprot.org/uniprot/P41811" } ], "reference": [ { "type": "PubMed", "id": "8405452", "url": "https://glygen.org/publication/PubMed/8405452" } ] }, { "title": "Sequence analysis of a 14.6 kb DNA fragment of Saccharomyces cerevisiae chromosome VII reveals SEC27, SSM1b, a putative S-adenosylmethionine-dependent enzyme and six new open reading frames.", "journal": "Yeast", "date": "1996", "authors": "Portillo F., Eraso P., Mazon M.J., Escribano V.", "evidence": [ { "database": "UniProtKB", "id": "P41811", "url": "https://www.uniprot.org/uniprot/P41811" } ], "reference": [ { "type": "PubMed", "id": "8840506", "url": "https://glygen.org/publication/PubMed/8840506" } ] }, { "title": "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.", "journal": "Nature", "date": "1997", "authors": "Mewes H.-W., Minenkova O., Schaefer M., Scharfe M., Wambutt R., Wedler H., Verhasselt P., Hansen M., Rose M., Durand P., Brueckner M., Plevani P., Netter P., Rieger M., Zimmermann M., Portetelle D., Wolf K., Bertani I., Delius H., Kleine K., Portillo F., Hofmann B., Albers M., Schaefer B., Kramer W., Castagnoli L., Volckaert G., Koetter P., Entian K.-D., Kramer B., Rinaldi T., Thierry A., Louis E.J., Vandenbol M., Martegani E., Robben J., Nombela C., Vanoni M., Arroyo J., Eraso P., Mazon M.J., James C.M., Carignani G., Dujon B., Feuermann M., Goffeau A., Hani J., Hilger F., Klima R., Mueller-Auer S., Oliver S.G., Potier S., Rodrigues-Pousada C., Schmidheini T., Souciet J.-L., Steensma H.Y., Zollner A., Bruschi C.V., Escribano V., Frontali L., Guerreiro P., Mazzoni C., Purnelle B., Rodriguez-Torres A.M., Skala J., Talla E., Voet M., de Wergifosse P., Agostoni-Carbone M.L., Albermann K., Backes U., Barreiros T., Bjourson A.J., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E., Defoor E., Del Bino S., Delneri D., Fabiani L., Fartmann B., Feroli F., Garcia-Gonzalez M., Garcia-Saez M.I., Hebling U., Hernandez K., Heumann K., Indge K.J., Lauquin G., Leuther H., Maillier E., Marconi A., McReynolds A.D.K., Melchioretto P., Nawrocki A., Neu R., Panzeri L., Paoluzi S., Riles L., Rodriguez-Belmonte E., Ruzzi M., Saliola M., Sanchez-Perez M., Schreer A., Tettelin H., Van Dyck L., Watson M.D., Weber N., Wedler E., Wipfli P., Wright L.F., Zaccaria P., van der Aart Q.J.M.", "evidence": [ { "database": "UniProtKB", "id": "P41811", "url": "https://www.uniprot.org/uniprot/P41811" } ], "reference": [ { "type": "PubMed", "id": "9169869", "url": "https://glygen.org/publication/PubMed/9169869" } ] } ], "pathway": [ { "id": "sce:YGL137W", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YGL137W", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O55029-1", "protein_name": "Coatomer subunit beta'", "gene_name": "Copb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLRLDIKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLRGSNNVALGYDEGSIIVKLGREEPAMSMDANGKIIWAKHSEVQQANLKAMGDTEIKDGERLPLAVKDMGSCEIYPQTIQHNPNGRFVVVCGDGEYIIYTAMALRNKSFGSAQEFAWAHDSSEYAIRESNSIVKIFKNFKEKKSFKPDFGAESIYGGFLLGVRSVNGLAFYDWENTELIRRIEIQPKHIFWSDSGELVCIATEESFFILKYLSEKVLAAQETHEGVTEDGIEDAFEVLGEIQEIVKTGLWVGDCFIYTSSVNRLNYYVGGEIVTIAHLDRTMYLLGYIPKDNRLYLGDKELNIVSYSLLVSVLEYQTAVMRRDFSMADKVLPTIPKEQRTRVAHFLEKQGFKQQALTVSTDPEHRFELALQLGELKIAYQLAVEAESEQKWKQLAELAISKCQFSLAQECLHHAQDYGGLLLLATASGNASMVNKLAEGAERDGKNNVAFMSYFLQGKLDACLELLIRTGRLPEAAFLARTYLPSQVSRVVKLWRENLSKVNQKAAESLADPTEYENLFPGLKEAFVVEEWVKETHADLWPAKQYPLVTPNEERNVMEEAKGFQPSRPTAQQEPDGKPASSPVIMASQTTHKEEKSLLELEVDLDNLELEDIDTTDINLDEDILDD", "length": 905 }, "evidence": [ { "id": "P41811", "url": 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