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"MKYPAFSINSDTVHLTDNPLDDYQRLYLVSVLDRDSPPASFSAGLNIRKVNYKSSIAAQFTHPNFIISARDAGNGEEAAAQNVLNCFEYQFPNLQTIQSLVHEQTLLSQLASSATPHSALHLHDKNILMGKIILPSRSNKTPVSASPTKQEKKALSTASRENATSSLTKNQQFKLTKMDHNLINDKLINPNNCVIWSHDSGYVFMTGIWRLYQDVMKGLINLPRGDSVSTSQQQFFCKAEFEKILSFCFYNHSSFTSEESSSVLLSSSTSSPPKRRTSTGSTFLDANASSSSTSSTQANNYIDFHWNNIKPELRDLICQSYKDFLINELGPDQIDLPNLNPANFTKRIRGGYIKIQGTWLPMEISRLLCLRFCFPIRYFLVPIFGPDFPKDCESWYLAHQNVTFASSTTGAGAATAATAAANTSTNFTSTAVARPRQKPRPRPRQRSTSMSHSKAQKLVIEDALPSFDSFVENLGLSSNDKNFIKKNSKRQKSSTYTSQTSSPIGPRDPTVQILSNLASFYNTHGHRYSYPGNIYIPQQRYSLPPPNQLSSPQRQLNYTYDHIHPVPSQYQSPRHYNVPSSPIAPAPPTFPQPYGDDHYHFLKYASEVYKQQNQRPAHNTNTNMDTSFSPRANNSLNNFKFKTNSKQ", "length": 647, "header": "sp|P40489-1|XBP1_YEAST Isoform 1 of Transcriptional repressor XBP1 OS=Saccharomyces cerevisiae S288C OX=559292 GN=XBP1 PE=1 SV=1 CANONICAL=P40489-1" }, "isoforms": [ { "isoform_ac": "P40489-1", "url": "", "sequence": { "sequence": "MKYPAFSINSDTVHLTDNPLDDYQRLYLVSVLDRDSPPASFSAGLNIRKVNYKSSIAAQFTHPNFIISARDAGNGEEAAAQNVLNCFEYQFPNLQTIQSLVHEQTLLSQLASSATPHSALHLHDKNILMGKIILPSRSNKTPVSASPTKQEKKALSTASRENATSSLTKNQQFKLTKMDHNLINDKLINPNNCVIWSHDSGYVFMTGIWRLYQDVMKGLINLPRGDSVSTSQQQFFCKAEFEKILSFCFYNHSSFTSEESSSVLLSSSTSSPPKRRTSTGSTFLDANASSSSTSSTQANNYIDFHWNNIKPELRDLICQSYKDFLINELGPDQIDLPNLNPANFTKRIRGGYIKIQGTWLPMEISRLLCLRFCFPIRYFLVPIFGPDFPKDCESWYLAHQNVTFASSTTGAGAATAATAAANTSTNFTSTAVARPRQKPRPRPRQRSTSMSHSKAQKLVIEDALPSFDSFVENLGLSSNDKNFIKKNSKRQKSSTYTSQTSSPIGPRDPTVQILSNLASFYNTHGHRYSYPGNIYIPQQRYSLPPPNQLSSPQRQLNYTYDHIHPVPSQYQSPRHYNVPSSPIAPAPPTFPQPYGDDHYHFLKYASEVYKQQNQRPAHNTNTNMDTSFSPRANNSLNNFKFKTNSKQ", "length": 647, "header": "sp|P40489-1|XBP1_YEAST Isoform 1 of Transcriptional repressor XBP1 OS=Saccharomyces cerevisiae S288C OX=559292 GN=XBP1 PE=1 SV=1 CANONICAL=P40489-1" }, "locus": { "chromosome": "IX", "start_pos": 177250, "end_pos": 175310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "YIL101C_mRNA", "url": "https://www.ensembl.org/id/YIL101C_mRNA" }, { "database": "Ensembl Peptide", "id": "YIL101C", "url": "https://www.ensembl.org/id/YIL101C" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 141, "end_pos": 141, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P40489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40489" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ], "site_lbl": "Thr141" }, { "start_pos": 146, "end_pos": 146, "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P40489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40489" }, { "database": "PubMed", "id": "21467995", "url": "https://glygen.org/publication/PubMed/21467995" } ], "site_lbl": "Ser146" }, { "start_pos": 146, "end_pos": 146, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P40489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40489" }, { "database": "PubMed", "id": "21467995", "url": "https://glygen.org/publication/PubMed/21467995" }, { "database": "SGD", "id": "P40489", "url": "https://www.yeastgenome.org/locus/P40489" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ], "site_lbl": "Ser146" }, { "start_pos": 271, "end_pos": 271, "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P40489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40489" }, { "database": "PubMed", "id": "21467995", "url": "https://glygen.org/publication/PubMed/21467995" } ], "site_lbl": "Ser271" }, { "start_pos": 271, "end_pos": 271, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P40489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40489" }, { "database": "PubMed", "id": "21467995", "url": "https://glygen.org/publication/PubMed/21467995" }, { "database": "SGD", "id": "P40489", "url": "https://www.yeastgenome.org/locus/P40489" } ], "site_lbl": "Ser271" }, { "start_pos": 551, "end_pos": 551, "kinase_uniprot_canonical_ac": "P00546-1", "kinase_gene_name": "CDC28", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P40489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40489" }, { "database": "PubMed", "id": "21467995", "url": "https://glygen.org/publication/PubMed/21467995" } ], "site_lbl": "Ser551" }, { "start_pos": 551, "end_pos": 551, 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phosphoproteome analysis.", "journal": "Mol. Cell. Proteomics", "date": "2008", "authors": "Albuquerque Claudio P, Smolka Marcus B, Payne Samuel H, Bafna Vineet, Eng Jimmy, Zhou Huilin", "evidence": [ { "database": "UniProtKB", "id": "P40489", "url": "https://www.uniprot.org/uniprot/P40489" }, { "database": "iPTMnet", "id": "P40489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40489" } ], "reference": [ { "type": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" } ] }, { "title": "Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.", "journal": "Genes & development", "date": "2009-08-15", "authors": "Huber Alexandre, Bodenmiller Bernd, Uotila Aino, Stahl Michael, Wanka Stefanie, Gerrits Bertran, Aebersold Ruedi, Loewith Robbie", "evidence": [ { "database": "iPTMnet", "id": "P40489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40489" } ], "reference": [ { "type": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" } ] }, { "title": "Xbp1-mediated histone H4 deacetylation contributes to DNA double-strand break repair in yeast.", "journal": "Cell research", "date": "2011-11", "authors": "Tao Ran, Chen Hua, Gao Chan, Xue Peng, Yang Fuquan, Han Jing-Dong J, Zhou Bing, Chen Ye-Guang", "evidence": [ { "database": "iPTMnet", "id": "P40489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40489" } ], "reference": [ { "type": "PubMed", "id": "21467995", "url": "https://glygen.org/publication/PubMed/21467995" } ] }, { "title": "Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.", "journal": "Nature methods", "date": "2013-07", "authors": "Swaney Danielle L, Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "P40489", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P40489" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.", "journal": "G3 (Bethesda)", "date": "2014", "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael", "evidence": [ { "database": "UniProtKB", "id": "P40489", "url": "https://www.uniprot.org/uniprot/P40489" } ], "reference": [ { "type": "PubMed", "id": "24374639", "url": "https://glygen.org/publication/PubMed/24374639" } ] }, { "title": "Similar short elements in the 5' regions of the STA2 and SGA genes from Saccharomyces cerevisiae.", "journal": "FEBS Lett.", "date": "1988", "authors": "Jimenez A., Pardo J.M., Claros M.G., Ianez E., Zalacain M.", "evidence": [ { "database": "UniProtKB", "id": "P40489", "url": "https://www.uniprot.org/uniprot/P40489" } ], "reference": [ { "type": "PubMed", "id": "3141213", "url": "https://glygen.org/publication/PubMed/3141213" } ] }, { "title": "The nucleotide sequence of Saccharomyces cerevisiae chromosome IX.", "journal": "Nature", "date": "1997", "authors": "Connor R., Gentles S., Jones M., Pearson D., Smith V., Bowman S., Hunt S., Bankier A.T., Barrell B.G., Skelton J., Brown D., Rice P., Odell C., Whitehead S., Harris D.E., Badcock K., Chillingworth T., Churcher C.M., Devlin K., Hamlin N., Jagels K., Lye G., Moule S., Rajandream M.A., Rowley N., Walsh S.V., Horsnell T.", "evidence": [ { "database": "UniProtKB", "id": "P40489", "url": "https://www.uniprot.org/uniprot/P40489" } ], "reference": [ { "type": "PubMed", "id": "9169870", "url": "https://glygen.org/publication/PubMed/9169870" } ] }, { "title": "Xbp1, a stress-induced transcriptional repressor of the Saccharomyces cerevisiae Swi4/Mbp1 family.", "journal": "Mol. Cell. Biol.", "date": "1997", "authors": "Mai B., Breeden L.", "evidence": [ { "database": "UniProtKB", "id": "P40489", "url": "https://www.uniprot.org/uniprot/P40489" } ], "reference": [ { "type": "PubMed", "id": "9343412", "url": "https://glygen.org/publication/PubMed/9343412" } ] } ], "pathway": [ { "id": "sce:YIL101C", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YIL101C", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of transcription involved in G1/S transition of mitotic cell cycle", "id": "GO:0071931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071931", "evidence": [ { "database": "UniProtKB", "id": "P40489", "url": "https://www.uniprot.org/uniprot/P40489" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", 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