{ "uniprot_canonical_ac": "P40008-1", "uniprot_ac": "P40008", "uniprot_id": "FMP52_YEAST", "mass": { "chemical_mass": 25086.0, "monoisotopic_mass": 25086.0 }, "refseq": { "ac": "NP_010919", "name": "Fmp52p", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010919" }, "gene_names": [ { "name": "FMP52", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P40008", "id": "P40008" }, { "name": "FMP52", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010919", "id": "NP_010919" } ], "protein_names": [ { "name": "Protein FMP52, mitochondrial", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P40008" }, { "name": "Fmp52p", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010919", "id": "NP_010919" }, { "name": "Found in mitochondrial proteome protein 52", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P40008" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P40008", "url": "https://www.uniprot.org/uniprot/P40008" } ], "common_name": "Yeast" } ], "gene": [ { "name": "FMP52", "url": "https://www.uniprot.org/uniprot/P40008", "locus": {} } ], "crossref": [ { "id": "cd05250", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05250", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "856721", "url": "https://www.ncbi.nlm.nih.gov/gene/856721", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "P40008", "url": "https://www.ebi.ac.uk/intact/interactors/id:P40008*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR014843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "sce:YER004W", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YER004W", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GMIIGRE", "url": "https://omabrowser.org/oma/group/GMIIGRE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "1457777at2759", "url": "http://www.orthodb.org/?query=1457777at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14097", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14097", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14097:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14097:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08732", "url": "http://pfam.xfam.org/family/PF08732", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_P40008", "url": "http://purl.obolibrary.org/obo/PR_P40008", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_010919", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010919", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "S000000806", "url": "https://www.yeastgenome.org/locus/S000000806", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P40008", "url": "https://www.uniprot.org/uniprot/P40008", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P40008-1", "url": "https://www.uniprot.org/uniprot/P40008-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGLVLGATGLCGGGFLRHAQEAPQFSKVYAILRRELPFPATDKVVAIVERDNSKWSQLITNEMNPQVLFTALATTRAAAGGLDKQYKIDHDLNLQLAQAAKEKGCETIVLVSSAGAHPDSRFGYMKMKGEIERDVIALDFKHIIILRPGPLLGERTNSKQSGFGGNLTAALGTRVYRSRFQRLLGYPVYGDEVGKVGVHLALNTSGKDKVQFVSSKDILDISASLEKIAT", "length": 231, "header": "sp|P40008-1|FMP52_YEAST Isoform 1 of Protein FMP52, mitochondrial OS=Saccharomyces cerevisiae S288C OX=559292 GN=FMP52 PE=1 SV=1 CANONICAL=P40008-1" }, "isoforms": [ { "isoform_ac": "P40008-1", "url": "", "sequence": { "sequence": "MNGLVLGATGLCGGGFLRHAQEAPQFSKVYAILRRELPFPATDKVVAIVERDNSKWSQLITNEMNPQVLFTALATTRAAAGGLDKQYKIDHDLNLQLAQAAKEKGCETIVLVSSAGAHPDSRFGYMKMKGEIERDVIALDFKHIIILRPGPLLGERTNSKQSGFGGNLTAALGTRVYRSRFQRLLGYPVYGDEVGKVGVHLALNTSGKDKVQFVSSKDILDISASLEKIAT", "length": 231, "header": "sp|P40008-1|FMP52_YEAST Isoform 1 of Protein FMP52, mitochondrial OS=Saccharomyces cerevisiae S288C OX=559292 GN=FMP52 PE=1 SV=1 CANONICAL=P40008-1" }, "locus": { "chromosome": "V", "start_pos": 160272, "end_pos": 159580, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "YER004W_mRNA", "url": "https://www.ensembl.org/id/YER004W_mRNA" }, { "database": "Ensembl Peptide", "id": "YER004W", "url": "https://www.ensembl.org/id/YER004W" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Global analysis of protein expression in yeast.", "journal": "Nature", "date": "2003", "authors": "Dephoure N., Weissman J.S., Howson R.W., Huh W.-K., O'Shea E.K., Belle A., Bower K., Ghaemmaghami S.", "evidence": [ { "database": "UniProtKB", "id": "P40008", "url": "https://www.uniprot.org/uniprot/P40008" } ], "reference": [ { "type": "PubMed", "id": "14562106", "url": "https://glygen.org/publication/PubMed/14562106" } ] }, { "title": "The proteome of Saccharomyces cerevisiae mitochondria.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2003", "authors": "Sickmann A., Zahedi R.P., Rehling P., Chacinska A., Guiard B., Meyer H.E., Meisinger C., Reinders J., Pfanner N., Joppich C., Perschil I., Schoenfisch B., Wagner Y.", "evidence": [ { "database": "UniProtKB", "id": "P40008", "url": "https://www.uniprot.org/uniprot/P40008" } ], "reference": [ { "type": "PubMed", "id": "14576278", "url": "https://glygen.org/publication/PubMed/14576278" } ] }, { "title": "Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.", "journal": "Mol. Biol. Cell", "date": "2006", "authors": "Sickmann A., Zahedi R.P., Guiard B., Winkler C., Meisinger C., Pfanner N., Zufall N., Boehm A.M., Schoenfisch B.", "evidence": [ { "database": "UniProtKB", "id": "P40008", "url": "https://www.uniprot.org/uniprot/P40008" } ], "reference": [ { "type": "PubMed", "id": "16407407", "url": "https://glygen.org/publication/PubMed/16407407" } ] }, { "title": "Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.", "journal": "Genome Res.", "date": "2007", "authors": "Hu Y., LaBaer J., Moreira D., Raphael J., Rolfs A., Zuo D., Richardson A., Simpson A.J.G., Zhu C., Harlow E., Camargo A.A., Jepson D., Kelley F., McCarron S., Taycher E., Kolodner R.D., Kane M.F., Williamson J., Berger M.F., Bulyk M.L., Bhullar B., Mohr S., Marsischky G., Murthy T.V.S.", "evidence": [ { "database": "UniProtKB", "id": "P40008", "url": "https://www.uniprot.org/uniprot/P40008" } ], "reference": [ { "type": "PubMed", "id": "17322287", "url": "https://glygen.org/publication/PubMed/17322287" } ] }, { "title": "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2012", "authors": "Van Damme P, Lasa M, Polevoda B, Gazquez C, Elosegui-Artola A, Kim DS, De Juan-Pardo E, Demeyer K, Hole K, Larrea E, Timmerman E, Prieto J, Arnesen T, Sherman F, Gevaert K, Aldabe R", "evidence": [ { "database": "UniProtKB", "id": "P40008", "url": "https://www.uniprot.org/uniprot/P40008" } ], "reference": [ { "type": "PubMed", "id": "22814378", "url": "https://glygen.org/publication/PubMed/22814378" } ] }, { "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.", "journal": "G3 (Bethesda)", "date": "2014", "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael", "evidence": [ { "database": "UniProtKB", "id": "P40008", "url": "https://www.uniprot.org/uniprot/P40008" } ], "reference": [ { "type": "PubMed", "id": "24374639", "url": "https://glygen.org/publication/PubMed/24374639" } ] }, { "title": "The nucleotide sequence of Saccharomyces cerevisiae chromosome V.", "journal": "Nature", "date": "1997", "authors": "Smith V., Chen E., Guzman E., Chung E., Nakahara K., Botstein D., Davis R.W., Lin D., Wei Y., Duncan M., Berno A., Oh C., Oefner P., Taylor P., Lashkari D., Allen E., Hyman R.W., Araujo R., Komp C., Lew H., Namath A., Roberts D., Mulligan J.T., Sehl P., Schramm S., Hartzell G., Cherry J.M., Dietrich F.S., Aviles E., Brennan T., Carpenter J., Hennessy K.M., Hunicke-Smith S., Kayser A., Mosedale D., Norgren R., Petel F.X., Shogren T., Yelton M.A.", "evidence": [ { "database": "UniProtKB", "id": "P40008", "url": "https://www.uniprot.org/uniprot/P40008" } ], "reference": [ { "type": "PubMed", "id": "9169868", "url": "https://glygen.org/publication/PubMed/9169868" } ] } ], "pathway": [ { "id": "sce:YER004W", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YER004W", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P40008", "url": "https://www.uniprot.org/uniprot/P40008" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P40008", "url": "https://www.uniprot.org/uniprot/P40008" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "P40008", "url": "https://www.uniprot.org/uniprot/P40008" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": 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