{
    "uniprot_canonical_ac": "P39039-1",
    "uniprot_ac": "P39039",
    "uniprot_id": "MBL1_MOUSE",
    "mass": {
        "chemical_mass": 25396.0,
        "monoisotopic_mass": 25396.0
    },
    "refseq": {
        "ac": "NP_034905",
        "name": "mannose-binding protein A precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034905"
    },
    "gene_names": [
        {
            "name": "Mbl1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/P39039",
            "id": "P39039"
        },
        {
            "name": "MBL-A; MBP-A; S-MBP",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034905",
            "id": "NP_034905"
        },
        {
            "name": "Mbl1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034905",
            "id": "NP_034905"
        }
    ],
    "protein_names": [
        {
            "name": "Mannose-binding protein A",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "P39039"
        },
        {
            "name": "MBP-A",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P39039"
        },
        {
            "name": "Mannan-binding protein",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P39039"
        },
        {
            "name": "Ra-reactive factor polysaccharide-binding component p28B",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P39039"
        },
        {
            "name": "RaRF p28B",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P39039"
        },
        {
            "name": "mannose binding lectin (A); mannose-binding protein A; mannose binding lectin, serum (A); raRF p28B; mannan-binding protein; ra-reactive factor polysaccharide-binding component p28B",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034905",
            "id": "NP_034905"
        },
        {
            "name": "mannose-binding protein A precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034905",
            "id": "NP_034905"
        }
    ],
    "function": [
        {
            "annotation": "Calcium-dependent lectin. Plays a role in the innate immune response by binding mannose, fucose and N-acetylglucosamine moieties on different microorganisms and mediating activation of the lectin complement pathway (By similarity). Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P39039",
                    "url": "https://www.uniprot.org/uniprot/P39039#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "P19999",
                    "url": "https://www.uniprot.org/uniprot/P19999#function"
                }
            ]
        },
        {
            "annotation": "Mannan-Binding Lectin Promotes Murine Graft-versus-Host Disease by Amplifying Lipopolysaccharide-Initiated Inflammation.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_034905",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034905"
                },
                {
                    "database": "PubMed",
                    "id": "35643350",
                    "url": "https://glygen.org/publication/PubMed/35643350"
                }
            ]
        },
        {
            "annotation": "Mannose-binding lectin activates the nuclear factor-kappaB and renal inflammation in the progression of diabetic nephropathy.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_034905",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034905"
                },
                {
                    "database": "PubMed",
                    "id": "35195918",
                    "url": "https://glygen.org/publication/PubMed/35195918"
                }
            ]
        },
        {
            "annotation": "Mannose-binding lectin promotes blood-brain barrier breakdown and exacerbates axonal damage after traumatic brain injury in mice.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_034905",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034905"
                },
                {
                    "database": "PubMed",
                    "id": "34547288",
                    "url": "https://glygen.org/publication/PubMed/34547288"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P39039",
                    "url": "https://www.uniprot.org/uniprot/P39039"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Mbl1",
            "url": "https://www.uniprot.org/uniprot/P39039",
            "locus": {
                "chromosome": "14",
                "start_pos": 40881558,
                "end_pos": 40873415,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000037780",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000037780"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000037780",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000037780",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd03591",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03591",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "17194",
            "url": "https://www.ncbi.nlm.nih.gov/gene/17194",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR001304",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR008160",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR016186",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR016187",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018378",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018378",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR033990",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR033990",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:17194",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:17194",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "96923",
            "url": "http://www.informatics.jax.org/marker/MGI:96923",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "RLAYSNW",
            "url": "https://omabrowser.org/oma/group/RLAYSNW/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4172523at2759",
            "url": "http://www.orthodb.org/?query=4172523at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24024",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24024",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24024:SF35",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24024:SF35",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00059",
            "url": "http://pfam.xfam.org/family/PF00059",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF01391",
            "url": "http://pfam.xfam.org/family/PF01391",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_P39039",
            "url": "http://purl.obolibrary.org/obo/PR_P39039",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_034905",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034905",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A2C9F2B6",
            "url": "https://www.uniprot.org/uniprot/A0A2C9F2B6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A2C9F2B6-1",
            "url": "https://www.uniprot.org/uniprot/A0A2C9F2B6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P39039",
            "url": "https://www.uniprot.org/uniprot/P39039",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P39039-1",
            "url": "https://www.uniprot.org/uniprot/P39039-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P39039-2",
            "url": "https://www.uniprot.org/uniprot/P39039-2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MLLLPLLPVLLCVVSVSSSGSQTCEDTLKTCSVIACGRDGRDGPKGEKGEPGQGLRGLQGPPGKLGPPGSVGSPGSPGPKGQKGDHGDNRAIEEKLANMEAEIRILKSKLQLTNKLHAFSMGKKSGKKLFVTNHEKMPFSKVKSLCTELQGTVAIPRNAEENKAIQEVATGIAFLGITDEATEGQFMYVTGGRLTYSNWKKDEPNNHGSGEDCVIILDNGLWNDISCQASFKAVCEFPA",
        "length": 239,
        "header": "sp|P39039-1|MBL1_MOUSE Isoform 1 of Mannose-binding protein A  OS=Mus musculus OX=10090 GN=Mbl1 PE=1 SV=1 CANONICAL=P39039-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A2C9F2B6-1",
            "url": "",
            "sequence": {
                "sequence": "MLLLPLLPVLLCVVSVSSSGSQTCEDTLKTCSVIACGRDGRDGPKGEKGEPGIESRAQGLAGPSREIGASRKCWKPWKSRTKRPKGGPWRQ",
                "length": 91,
                "header": "tr|A0A2C9F2B6-1|MBL1_MOUSE Computationally mapped isoform of Mannose-binding protein A  OS=Mus musculus OX=10090 GN=Mbl1 PE=1 SV=1 CANONICAL=P39039-1"
            },
            "locus": {
                "chromosome": "14",
                "start_pos": 40876569,
                "end_pos": 40875548,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000047095.4",
                        "url": "https://www.ensembl.org/id/ENSMUST00000047095.4"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000048765.4",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000048765.4"
                    }
                ]
            }
        },
        {
            "isoform_ac": "P39039-1",
            "url": "",
            "sequence": {
                "sequence": "MLLLPLLPVLLCVVSVSSSGSQTCEDTLKTCSVIACGRDGRDGPKGEKGEPGQGLRGLQGPPGKLGPPGSVGSPGSPGPKGQKGDHGDNRAIEEKLANMEAEIRILKSKLQLTNKLHAFSMGKKSGKKLFVTNHEKMPFSKVKSLCTELQGTVAIPRNAEENKAIQEVATGIAFLGITDEATEGQFMYVTGGRLTYSNWKKDEPNNHGSGEDCVIILDNGLWNDISCQASFKAVCEFPA",
                "length": 239,
                "header": "sp|P39039-1|MBL1_MOUSE Isoform 1 of Mannose-binding protein A  OS=Mus musculus OX=10090 GN=Mbl1 PE=1 SV=1 CANONICAL=P39039-1"
            },
            "locus": {
                "chromosome": "14",
                "start_pos": 40880830,
                "end_pos": 40875548,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000225792",
                        "url": "https://www.ensembl.org/id/ENSMUST00000225792"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000153147",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000153147"
                    }
                ]
            }
        },
        {
            "isoform_ac": "P39039-2",
            "url": "",
            "sequence": {
                "sequence": "MEAEIRILKSKLQLTNKLHAFSMGKKSGKKLFVTNHEKMPFSKVKSLCTELQGTVAIPRNAEENKAIQEVATGIAFLGITDEATEGQFMYVTGGRLTYSNWKKDEPNNHGSGEDCVIILDNGLWNDISCQASFKAVCEFPA",
                "length": 141,
                "header": "sp|P39039-2|MBL1_MOUSE Isoform 2 of Mannose-binding protein A  OS=Mus musculus OX=10090 GN=Mbl1 PE=1 SV=1 CANONICAL=P39039-1"
            },
            "locus": {}
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "O-linked",
            "subtype": "O-galactosylation",
            "site_category": "predicted",
            "site_seq": "K",
            "relation": "attached",
            "comment": "O-linked (Gal...) hydroxylysine O-galactosylation",
            "start_pos": 45,
            "start_aa": "Lys",
            "end_pos": 45,
            "end_aa": "Lys",
            "residue": "Lys",
            "site_lbl": "Lys45",
            "evidence": [
                {
                    "id": "P39039",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P39039#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "O-linked",
            "subtype": "O-galactosylation",
            "site_category": "predicted",
            "site_seq": "K",
            "relation": "attached",
            "comment": "O-linked (Gal...) hydroxylysine O-galactosylation",
            "start_pos": 48,
            "start_aa": "Lys",
            "end_pos": 48,
            "end_aa": "Lys",
            "residue": "Lys",
            "site_lbl": "Lys48",
            "evidence": [
                {
                    "id": "P39039",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P39039#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "O-linked",
            "subtype": "O-galactosylation",
            "site_category": "predicted",
            "site_seq": "K",
            "relation": "attached",
            "comment": "O-linked (Gal...) hydroxylysine O-galactosylation",
            "start_pos": 80,
            "start_aa": "Lys",
            "end_pos": 80,
            "end_aa": "Lys",
            "residue": "Lys",
            "site_lbl": "Lys80",
            "evidence": [
                {
                    "id": "P39039",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P39039#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "O-linked",
            "subtype": "O-galactosylation",
            "site_category": "predicted",
            "site_seq": "K",
            "relation": "attached",
            "comment": "O-linked (Gal...) hydroxylysine O-galactosylation",
            "start_pos": 83,
            "start_aa": "Lys",
            "end_pos": 83,
            "end_aa": "Lys",
            "residue": "Lys",
            "site_lbl": "Lys83",
            "evidence": [
                {
                    "id": "P39039",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P39039#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [
        {
            "title": "cDNAs and deduced amino acid sequences of subunits in the binding component of mouse bactericidal factor, Ra-reactive factor: similarity to mannose-binding proteins.",
            "journal": "Biochemistry",
            "date": "1992",
            "authors": "Kuge S, Ihara S, Watanabe E, Watanabe M, Takishima K, Suga T, Mamiya G, Kawakami M",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P39039",
                    "url": "https://www.uniprot.org/uniprot/P39039"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "1637828",
                    "url": "https://glygen.org/publication/PubMed/1637828"
                }
            ]
        },
        {
            "title": "Molecular characterization of the mouse mannose-binding proteins. The mannose-binding protein A but not C is an acute phase reactant.",
            "journal": "J. Immunol.",
            "date": "1991",
            "authors": "Sastry K, Zahedi K, Lelias JM, Whitehead AS, Ezekowitz RA",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P39039",
                    "url": "https://www.uniprot.org/uniprot/P39039"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "1712818",
                    "url": "https://glygen.org/publication/PubMed/1712818"
                }
            ]
        },
        {
            "title": "Lysyl hydroxylase 3 modifies lysine residues to facilitate oligomerization of mannan-binding lectin.",
            "journal": "PLoS ONE",
            "date": "2014",
            "authors": "Risteli M, Ruotsalainen H, Bergmann U, Venkatraman Girija U, Wallis R, Myllyla R",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P39039",
                    "url": "https://www.uniprot.org/uniprot/P39039"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "25419660",
                    "url": "https://glygen.org/publication/PubMed/25419660"
                }
            ]
        },
        {
            "title": "Mannose-binding lectin promotes blood-brain barrier breakdown and exacerbates axonal damage after traumatic brain injury in mice.",
            "journal": "Experimental neurology",
            "date": "2021",
            "authors": "Pedragosa J, Mercurio D, Oggioni M, Marquez-Kisinousky L, de Simoni MG, Planas AM",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_034905",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034905"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "34547288",
                    "url": "https://glygen.org/publication/PubMed/34547288"
                }
            ]
        },
        {
            "title": "Mannose-binding lectin activates the nuclear factor-kappaB and renal inflammation in the progression of diabetic nephropathy.",
            "journal": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology",
            "date": "2022",
            "authors": "Ma Y, Cai F, Huang X, Wang H, Yu B, Wang J, Nie W, Cai K, Yang Y, Chen J, Xiao L, Han F",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_034905",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034905"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "35195918",
                    "url": "https://glygen.org/publication/PubMed/35195918"
                }
            ]
        },
        {
            "title": "Mannan-Binding Lectin Promotes Murine Graft-versus-Host Disease by Amplifying Lipopolysaccharide-Initiated Inflammation.",
            "journal": "Transplantation and cellular therapy",
            "date": "2022",
            "authors": "Heja D, Zhao D, Cody E, Cumpelik A, Lim PC, Prado-Acosta M, Palma L, Dellepiane S, Chun N, Ferrara J, Heeger PS",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_034905",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_034905"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "35643350",
                    "url": "https://glygen.org/publication/PubMed/35643350"
                }
            ]
        },
        {
            "title": "Characterization of murine mannose-binding protein genes Mbl1 and Mbl2 reveals features common to other collectin genes.",
            "journal": "Mamm. Genome",
            "date": "1995",
            "authors": "Sastry R, Wang JS, Brown DC, Ezekowitz RA, Tauber AI, Sastry KN",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P39039",
                    "url": "https://www.uniprot.org/uniprot/P39039"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "7766991",
                    "url": "https://glygen.org/publication/PubMed/7766991"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:17194",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:17194",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "P19999-1",
            "protein_name": "Mannose-binding protein A",
            "gene_name": "Mbl1",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MLLLPLLVLLCVVSVSSSGSQTCEETLKTCSVIACGRDGRDGPKGEKGEPGQGLRGLQGPPGKLGPPGSVGAPGSQGPKGQKGDRGDSRAIEVKLANMEAEINTLKSKLELTNKLHAFSMGKKSGKKFFVTNHERMPFSKVKALCSELRGTVAIPRNAEENKAIQEVAKTSAFLGITDEVTEGQFMYVTGGRLTYSNWKKDEPNDHGSGEDCVTIVDNGLWNDISCQASHTAVCEFPA",
                "length": 238
            },
            "evidence": [
                {
                    "id": "45230884",
                    "url": "http://www.informatics.jax.org/homology/45230884",
                    "database": "MGI"
                },
                {
                    "id": "P39039",
                    "url": "https://omabrowser.org/oma/group/P39039/",
                    "database": "OMA"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 10,
                "go_terms": [
                    {
                        "name": "polysaccharide binding",
                        "id": "GO:0030247",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030247",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "oligosaccharide binding",
                        "id": "GO:0070492",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070492",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protease binding",
                        "id": "GO:0002020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "identical protein binding",
                        "id": "GO:0042802",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein homodimerization activity",
                        "id": "GO:0042803",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "calcium-dependent protein binding",
                        "id": "GO:0048306",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "calcium ion binding",
                        "id": "GO:0005509",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "phosphatidylinositol-4-phosphate binding",
                        "id": "GO:0070273",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070273",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mannose binding",
                        "id": "GO:0005537",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005537",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "calcium-dependent carbohydrate binding",
                        "id": "GO:0120153",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120153",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 4,
                "go_terms": [
                    {
                        "name": "extracellular space",
                        "id": "GO:0005615",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "rough endoplasmic reticulum",
                        "id": "GO:0005791",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "collagen trimer",
                        "id": "GO:0005581",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005581",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "multivesicular body",
                        "id": "GO:0005771",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 7,
                "go_terms": [
                    {
                        "name": "surfactant homeostasis",
                        "id": "GO:0043129",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043129",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "defense response to Gram-positive bacterium",
                        "id": "GO:0050830",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of phagocytosis",
                        "id": "GO:0050766",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050766",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein homotrimerization",
                        "id": "GO:0070207",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070207",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "complement activation, lectin pathway",
                        "id": "GO:0001867",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001867",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "killing by host of symbiont cells",
                        "id": "GO:0051873",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051873",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "complement activation, classical pathway",
                        "id": "GO:0006958",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006958",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P39039",
                                "url": "https://www.uniprot.org/uniprot/P39039"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [
        {
            "annotation": "Hydroxylated on lysine and proline residues within the collagen-like domain.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P39039",
                    "url": "https://www.uniprot.org/uniprot/P39039"
                },
                {
                    "database": "PubMed",
                    "id": "P19999",
                    "url": "https://glygen.org/publication/PubMed/P19999"
                }
            ]
        },
        {
            "annotation": "O-glycosylated. O-linked glycans on hydroxylysine residues consist of Glc-Gal disaccharides bound to the oxygen atom of post-translationally added hydroxyl groups.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P39039",
                    "url": "https://www.uniprot.org/uniprot/P39039"
                },
                {
                    "database": "PubMed",
                    "id": "P19999",
                    "url": "https://glygen.org/publication/PubMed/P19999"
                }
            ]
        }
    ],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 4
                },
                {
                    "field": "total_sites",
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                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": [
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        },
        {
            "table_id": "glycosylation_reported",
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                },
                {
                    "field": "n_linked_glycan_sites",
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                },
                {
                    "field": "o_linked_glycans",
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                },
                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
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                {
                    "field": "o_linked_glycans",
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                {
                    "field": "o_linked_glycan_sites",
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            ],
            "sort_fields": []
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        {
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                {
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        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
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                    "field": "o_linked_glycan_sites",
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            ],
            "sort_fields": []
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        {
            "table_id": "phosphorylation",
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        {
            "table_id": "snv",
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            ],
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        {
            "table_id": "snv_disease",
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                {
                    "field": "total_sites",
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        {
            "table_id": "snv_non_disease",
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    ]
}