{
    "uniprot_canonical_ac": "P38993-1",
    "uniprot_ac": "P38993",
    "uniprot_id": "FET3_YEAST",
    "mass": {
        "chemical_mass": 72360.0,
        "monoisotopic_mass": 72360.0
    },
    "refseq": {
        "ac": "NP_013774",
        "name": "ferroxidase FET3",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013774"
    },
    "gene_names": [
        {
            "name": "FET3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/P38993",
            "id": "P38993"
        },
        {
            "name": "FET3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013774",
            "id": "NP_013774"
        },
        {
            "name": "YM9796.11",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/P38993",
            "id": "P38993"
        }
    ],
    "protein_names": [
        {
            "name": "Iron transport multicopper oxidase FET3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "P38993"
        },
        {
            "name": "1.16.3.1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P38993"
        },
        {
            "name": "ferroxidase FET3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013774",
            "id": "NP_013774"
        }
    ],
    "function": [
        {
            "annotation": "Iron transport multicopper ferroxidase required for Fe(2+) ion high affinity uptake. Required to oxidize Fe(2+) to Fe(3+), which is then transported into the cell via the ferric iron permease FTR1. Essential component of copper-dependent iron transport.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P38993",
                    "url": "https://www.uniprot.org/uniprot/P38993#function"
                },
                {
                    "database": "PubMed",
                    "id": "8293473",
                    "url": "https://glygen.org/publication/PubMed/8293473"
                },
                {
                    "database": "PubMed",
                    "id": "7836366",
                    "url": "https://glygen.org/publication/PubMed/7836366"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Saccharomyces cerevisiae S288C",
            "taxid": 559292,
            "evidence": [
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                    "database": "UniProtKB",
                    "id": "P38993",
                    "url": "https://www.uniprot.org/uniprot/P38993"
                }
            ],
            "common_name": "Yeast"
        }
    ],
    "gene": [
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            "name": "FET3",
            "url": "https://www.uniprot.org/uniprot/P38993",
            "locus": {}
        }
    ],
    "crossref": [
        {
            "id": "cd13851",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13851",
            "database": "CDD",
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        },
        {
            "id": "cd13877",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13877",
            "database": "CDD",
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        },
        {
            "id": "cd13899",
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            "database": "CDD",
            "categories": [
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        },
        {
            "id": "855080",
            "url": "https://www.ncbi.nlm.nih.gov/gene/855080",
            "database": "GeneID",
            "categories": [
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        },
        {
            "id": "P38993",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:P38993*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR001117",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001117",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR002355",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002355",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR008972",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR008972",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR011706",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011706",
            "database": "InterPro",
            "categories": [
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            ]
        },
        {
            "id": "IPR011707",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011707",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR033138",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR033138",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR044130",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR044130",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR045087",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR045087",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "sce:YMR058W",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YMR058W",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "VHYDDTM",
            "url": "https://omabrowser.org/oma/group/VHYDDTM/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "449862at2759",
            "url": "http://www.orthodb.org/?query=449862at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11709",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11709",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11709:SF361",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11709:SF361",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1ZPU",
            "url": "https://www.rcsb.org/structure/1ZPU",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "PF00394",
            "url": "http://pfam.xfam.org/family/PF00394",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF07731",
            "url": "http://pfam.xfam.org/family/PF07731",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF07732",
            "url": "http://pfam.xfam.org/family/PF07732",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_P38993",
            "url": "http://purl.obolibrary.org/obo/PR_P38993",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_013774",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013774",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "S000004662",
            "url": "https://www.yeastgenome.org/locus/S000004662",
            "database": "SGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "P38993",
            "url": "https://www.uniprot.org/uniprot/P38993",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P38993-1",
            "url": "https://www.uniprot.org/uniprot/P38993-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
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        "sequence": "MTNALLSIAVLLFSMLSLAQAETHTFNWTTGWDYRNVDGLKSRPVITCNGQFPWPDITVNKGDRVQIYLTNGMNNTNTSMHFHGLFQNGTASMDGVPFLTQCPIAPGSTMLYNFTVDYNVGTYWYHSHTDGQYEDGMKGLFIIKDDSFPYDYDEELSLSLSEWYHDLVTDLTKSFMSVYNPTGAEPIPQNLIVNNTMNLTWEVQPDTTYLLRIVNVGGFVSQYFWIEDHEMTVVEIDGITTEKNVTDMLYITVAQRYTVLVHTKNDTDKNFAIMQKFDDTMLDVIPSDLQLNATSYMVYNKTAALPTQNYVDSIDNFLDDFYLQPYEKEAIYGEPDHVITVDVVMDNLKNGVNYAFFNNITYTAPKVPTLMTVLSSGDQANNSEIYGSNTHTFILEKDEIVEIVLNNQDTGTHPFHLHGHAFQTIQRDRTYDDALGEVPHSFDPDNHPAFPEYPMRRDTLYVRPQSNFVIRFKADNPGVWFFHCHIEWHLLQGLGLVLVEDPFGIQDAHSQQLSENHLEVCQSCSVATEGNAAANTLDLTDLTGENVQHAFIPTGFTKKGIIAMTFSCFAGILGIITIAIYGMMDMEDATEKVIRDLHVDPEVLLNEVDENEERQVNEDRHSTEKHQFLTKAKRFF",
        "length": 636,
        "header": "sp|P38993-1|FET3_YEAST Isoform 1 of Iron transport multicopper oxidase FET3  OS=Saccharomyces cerevisiae S288C OX=559292 GN=FET3 PE=1 SV=2 CANONICAL=P38993-1"
    },
    "isoforms": [
        {
            "isoform_ac": "P38993-1",
            "url": "",
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                "sequence": "MTNALLSIAVLLFSMLSLAQAETHTFNWTTGWDYRNVDGLKSRPVITCNGQFPWPDITVNKGDRVQIYLTNGMNNTNTSMHFHGLFQNGTASMDGVPFLTQCPIAPGSTMLYNFTVDYNVGTYWYHSHTDGQYEDGMKGLFIIKDDSFPYDYDEELSLSLSEWYHDLVTDLTKSFMSVYNPTGAEPIPQNLIVNNTMNLTWEVQPDTTYLLRIVNVGGFVSQYFWIEDHEMTVVEIDGITTEKNVTDMLYITVAQRYTVLVHTKNDTDKNFAIMQKFDDTMLDVIPSDLQLNATSYMVYNKTAALPTQNYVDSIDNFLDDFYLQPYEKEAIYGEPDHVITVDVVMDNLKNGVNYAFFNNITYTAPKVPTLMTVLSSGDQANNSEIYGSNTHTFILEKDEIVEIVLNNQDTGTHPFHLHGHAFQTIQRDRTYDDALGEVPHSFDPDNHPAFPEYPMRRDTLYVRPQSNFVIRFKADNPGVWFFHCHIEWHLLQGLGLVLVEDPFGIQDAHSQQLSENHLEVCQSCSVATEGNAAANTLDLTDLTGENVQHAFIPTGFTKKGIIAMTFSCFAGILGIITIAIYGMMDMEDATEKVIRDLHVDPEVLLNEVDENEERQVNEDRHSTEKHQFLTKAKRFF",
                "length": 636,
                "header": "sp|P38993-1|FET3_YEAST Isoform 1 of Iron transport multicopper oxidase FET3  OS=Saccharomyces cerevisiae S288C OX=559292 GN=FET3 PE=1 SV=2 CANONICAL=P38993-1"
            },
            "locus": {
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                "end_pos": 388822,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
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                        "url": "https://www.ensembl.org/id/YMR058W_mRNA"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "YMR058W",
                        "url": "https://www.ensembl.org/id/YMR058W"
                    }
                ]
            }
        }
    ],
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        {
            "glytoucan_ac": "",
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            "subtype": "",
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            "relation": "attached",
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                {
                    "id": "1ZPU",
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                },
                {
                    "id": "16230618",
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                    "url": "https://glygen.org/publication/PubMed/16230618"
                }
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        },
        {
            "glytoucan_ac": "",
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            "subtype": "",
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            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
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                },
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                },
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        {
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            "relation": "attached",
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                },
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                },
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        },
        {
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            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 244,
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                    "id": "P38993",
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                },
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                },
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                }
            ]
        },
        {
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            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 265,
            "start_aa": "Asn",
            "end_pos": 265,
            "end_aa": "Asn",
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            "site_lbl": "Asn265",
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                {
                    "id": "P38993",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P38993#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "reported",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 27,
            "start_aa": "Asn",
            "end_pos": 27,
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                    "id": "P38993",
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                {
                    "id": "16230618",
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                }
            ]
        },
        {
            "glytoucan_ac": "",
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            "subtype": "",
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            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
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            "end_aa": "Asn",
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                    "id": "P38993",
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                {
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                {
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        },
        {
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            "relation": "attached",
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                },
                {
                    "id": "1ZPU",
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                {
                    "id": "16230618",
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                }
            ]
        },
        {
            "glytoucan_ac": "",
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            "site_category": "reported",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
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            "start_aa": "Asn",
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                    "id": "P38993",
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                {
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            ]
        },
        {
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            "site_seq": "N",
            "relation": "attached",
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            "end_aa": "Asn",
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                {
                    "id": "P38993",
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                },
                {
                    "id": "1ZPU",
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                {
                    "id": "16230618",
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                    "url": "https://glygen.org/publication/PubMed/16230618"
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            ]
        },
        {
            "glytoucan_ac": "",
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            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
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            "start_aa": "Asn",
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                {
                    "id": "P38993",
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                    "url": "https://www.uniprot.org/uniprot/P38993#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
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            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
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            "start_aa": "Asn",
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                    "id": "P38993",
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                },
                {
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