{ "uniprot_canonical_ac": "P38860-1", "uniprot_ac": "P38860", "uniprot_id": "MTG2_YEAST", "mass": { "chemical_mass": 57847.0, "monoisotopic_mass": 57847.0 }, "refseq": { "ac": "NP_012038", "name": "putative GTPase MTG2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012038" }, "gene_names": [ { "name": "MTG2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P38860", "id": "P38860" }, { "name": "MTG2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012038", "id": "NP_012038" } ], "protein_names": [ { "name": "GTPase MTG2, mitochondrial", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P38860" }, { "name": "Mitochondrial GTPase 2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P38860" }, { "name": "putative GTPase MTG2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012038", "id": "NP_012038" } ], "function": [ { "annotation": "Required for mitochondrial protein synthesis. 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"P38860", "url": "https://www.ebi.ac.uk/intact/interactors/id:P38860*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036726", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036726", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045086", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045086", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "sce:YHR168W", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YHR168W", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PRVGHWE", "url": "https://omabrowser.org/oma/group/PRVGHWE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "232786at2759", "url": "http://www.orthodb.org/?query=232786at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11702", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11702", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11702:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11702:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01018", "url": "http://pfam.xfam.org/family/PF01018", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF01926", "url": "http://pfam.xfam.org/family/PF01926", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_P38860", "url": "http://purl.obolibrary.org/obo/PR_P38860", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_012038", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012038", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "S000001211", "url": "https://www.yeastgenome.org/locus/S000001211", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P38860", "url": "https://www.uniprot.org/uniprot/P38860", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P38860-1", "url": "https://www.uniprot.org/uniprot/P38860-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSIAWSSVFKRELRLERFLPRVYSTKVPDNAPRAADNEQWLETLRPITHPEQKKSDHDVSYTRHINVPLGEVTSVNYLQRYNKHKHSQGNFVDVRIVKCKSGAGGSGAVSFFRDAGRSIGPPDGGDGGAGGSVYIQAVAGLGSLAKMKTTYTAEDGEAGAARQLDGMRGRDVLIQVPVGTVVKWCLPPQKVRELVEREMRKDNNATLRSILGSTAVNLSVSSGSHRKKIQLYRHEMAESWLFKDKAKEYHENKDWFKDLHKKMEAYDHSLEQSELFNDQFPLAGLDLNQPMTKPVCLLKGGQGGLGNMHFLTNLIRNPRFSKPGRNGLEQHFLFELKSIADLGLIGLPNAGKSTILNKISNAKPKIGHWQFTTLSPTIGTVSLGFGQDVFTVADIPGIIQGASLDKGMGLEFLRHIERSNGWVFVLDLSNKNPLNDLQLLIEEVGTLEKVKTKNILIVCNKVDIDAEKSESFAKYLQVEKFSKSQEWDCVPISALREENIDVLKKKMFKCARQSEFDK", "length": 518, "header": "sp|P38860-1|MTG2_YEAST Isoform 1 of GTPase MTG2, mitochondrial OS=Saccharomyces cerevisiae S288C OX=559292 GN=MTG2 PE=1 SV=2 CANONICAL=P38860-1" }, "isoforms": [ { "isoform_ac": "P38860-1", "url": "", "sequence": { "sequence": "MSIAWSSVFKRELRLERFLPRVYSTKVPDNAPRAADNEQWLETLRPITHPEQKKSDHDVSYTRHINVPLGEVTSVNYLQRYNKHKHSQGNFVDVRIVKCKSGAGGSGAVSFFRDAGRSIGPPDGGDGGAGGSVYIQAVAGLGSLAKMKTTYTAEDGEAGAARQLDGMRGRDVLIQVPVGTVVKWCLPPQKVRELVEREMRKDNNATLRSILGSTAVNLSVSSGSHRKKIQLYRHEMAESWLFKDKAKEYHENKDWFKDLHKKMEAYDHSLEQSELFNDQFPLAGLDLNQPMTKPVCLLKGGQGGLGNMHFLTNLIRNPRFSKPGRNGLEQHFLFELKSIADLGLIGLPNAGKSTILNKISNAKPKIGHWQFTTLSPTIGTVSLGFGQDVFTVADIPGIIQGASLDKGMGLEFLRHIERSNGWVFVLDLSNKNPLNDLQLLIEEVGTLEKVKTKNILIVCNKVDIDAEKSESFAKYLQVEKFSKSQEWDCVPISALREENIDVLKKKMFKCARQSEFDK", "length": 518, "header": "sp|P38860-1|MTG2_YEAST Isoform 1 of GTPase MTG2, mitochondrial OS=Saccharomyces cerevisiae S288C OX=559292 GN=MTG2 PE=1 SV=2 CANONICAL=P38860-1" }, "locus": { "chromosome": "VIII", "start_pos": 441930, "end_pos": 440377, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "YHR168W_mRNA", "url": "https://www.ensembl.org/id/YHR168W_mRNA" }, { "database": "Ensembl Peptide", "id": "YHR168W", "url": "https://www.ensembl.org/id/YHR168W" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Global analysis of protein expression in yeast.", "journal": "Nature", "date": "2003", "authors": "Dephoure N., Weissman J.S., Howson R.W., Huh W.-K., O'Shea E.K., Belle A., Bower K., Ghaemmaghami S.", "evidence": [ { "database": "UniProtKB", "id": "P38860", "url": "https://www.uniprot.org/uniprot/P38860" } ], "reference": [ { "type": "PubMed", "id": "14562106", "url": "https://glygen.org/publication/PubMed/14562106" } ] }, { "title": "The yeast GTPase Mtg2p is required for mitochondrial translation and partially suppresses an rRNA methyltransferase mutant, mrm2.", "journal": "Mol. Biol. Cell", "date": "2005", "authors": "Datta K., Maddock J.R., Fuentes J.L.", "evidence": [ { "database": "UniProtKB", "id": "P38860", "url": "https://www.uniprot.org/uniprot/P38860" } ], "reference": [ { "type": "PubMed", "id": "15591131", "url": "https://glygen.org/publication/PubMed/15591131" } ] }, { "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.", "journal": "G3 (Bethesda)", "date": "2014", "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael", "evidence": [ { "database": "UniProtKB", "id": "P38860", "url": "https://www.uniprot.org/uniprot/P38860" } ], "reference": [ { "type": "PubMed", "id": "24374639", "url": "https://glygen.org/publication/PubMed/24374639" } ] }, { "title": "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.", "journal": "Science", "date": "1994", "authors": "Andrews S., Du Z., Fulton L., Hillier L.W., Latreille P., Mardis E., Vaudin M., Waterston R., Wilson R., Favello A., Kucaba T., Rifkin L., Trevaskis E., Wohldman P., Ding H., Cooper J., Vaughan K., Macri C., Louis E.J., Johnston L., Nhan M., Menezes S., Johnston M., Dover J., Wilcox L., Brinkman R., Gattung S., Geisel C., Jier M., Kirsten J., Langston Y., Mouser L., Riles L., St Peter H., Vignati D.", "evidence": [ { "database": "UniProtKB", "id": "P38860", "url": "https://www.uniprot.org/uniprot/P38860" } ], "reference": [ { "type": "PubMed", "id": "8091229", "url": "https://glygen.org/publication/PubMed/8091229" } ] } ], "pathway": [ { "id": "sce:YHR168W", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YHR168W", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "magnesium 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