{ "uniprot_canonical_ac": "P36521-1", "uniprot_ac": "P36521", "uniprot_id": "RM11_YEAST", "mass": { "chemical_mass": 28515.0, "monoisotopic_mass": 28515.0 }, "refseq": { "ac": "NP_010079", "name": "mitochondrial 54S ribosomal protein YmL11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010079" }, "gene_names": [ { "name": "MRPL11", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P36521", "id": "P36521" }, { "name": "D1070", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/P36521", "id": "P36521" }, { "name": "MRPL11", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010079", "id": "NP_010079" }, { "name": "uL10m", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010079", "id": "NP_010079" } ], "protein_names": [ { "name": "Large ribosomal subunit protein uL10m", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P36521" }, { "name": "54S ribosomal protein L11, mitochondrial", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P36521" }, { "name": "YmL11", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P36521" }, { "name": "mitochondrial 54S ribosomal protein YmL11", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010079", "id": "NP_010079" } ], "function": [ { "annotation": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.", "evidence": [ { "database": "UniProtKB", "id": "P36521", "url": "https://www.uniprot.org/uniprot/P36521#function" }, { "database": "PubMed", "id": "24675956", "url": "https://glygen.org/publication/PubMed/24675956" }, { "database": "PubMed", "id": "25609543", "url": "https://glygen.org/publication/PubMed/25609543" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P36521", "url": "https://www.uniprot.org/uniprot/P36521" } ], "common_name": "Yeast" } ], "gene": [ { "name": "MRPL11", "url": "https://www.uniprot.org/uniprot/P36521", "locus": {} } ], "crossref": [ { "id": "cd05797", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05797", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "851325", "url": "https://www.ncbi.nlm.nih.gov/gene/851325", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043141", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043141", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "sce:YDL202W", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YDL202W", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PLFKGPT", "url": "https://omabrowser.org/oma/group/PLFKGPT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "1985863at2759", "url": "http://www.orthodb.org/?query=1985863at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11560", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11560", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11560:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11560:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00466", "url": "http://pfam.xfam.org/family/PF00466", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_P36521", "url": "http://purl.obolibrary.org/obo/PR_P36521", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_010079", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010079", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "S000002361", "url": "https://www.yeastgenome.org/locus/S000002361", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P36521", "url": "https://www.uniprot.org/uniprot/P36521", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P36521-1", "url": "https://www.uniprot.org/uniprot/P36521-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQLRFMPGWVPRNGFFGLKETIGTVHKRFYALASEQPSRKTVKPLDSRKTFLIDTYKHLMENSSMIFFVHYNNLSKTEDHHFRFKIKQTGGKLTKVRNNLFEVYLRNSHLPDPCGFVKRKEQNWKHPLLPLLKGPTATITYEDTNPQQVAKLLKVLQSAQDKLMVIGAKVENEVLNVEKINTFKTLPTKPEMQSQLVSVLQMLSGLGLVRTLENSSNALYLTLKSHNDNQKPKEDVESTTDAESKGSK", "length": 249, "header": "sp|P36521-1|RM11_YEAST Isoform 1 of Large ribosomal subunit protein uL10m OS=Saccharomyces cerevisiae S288C OX=559292 GN=MRPL11 PE=1 SV=2 CANONICAL=P36521-1" }, "isoforms": [ { "isoform_ac": "P36521-1", "url": "", "sequence": { "sequence": "MLQLRFMPGWVPRNGFFGLKETIGTVHKRFYALASEQPSRKTVKPLDSRKTFLIDTYKHLMENSSMIFFVHYNNLSKTEDHHFRFKIKQTGGKLTKVRNNLFEVYLRNSHLPDPCGFVKRKEQNWKHPLLPLLKGPTATITYEDTNPQQVAKLLKVLQSAQDKLMVIGAKVENEVLNVEKINTFKTLPTKPEMQSQLVSVLQMLSGLGLVRTLENSSNALYLTLKSHNDNQKPKEDVESTTDAESKGSK", "length": 249, "header": "sp|P36521-1|RM11_YEAST Isoform 1 of Large ribosomal subunit protein uL10m OS=Saccharomyces cerevisiae S288C OX=559292 GN=MRPL11 PE=1 SV=2 CANONICAL=P36521-1" }, "locus": { "chromosome": "IV", "start_pos": 99221, "end_pos": 98475, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "YDL202W_mRNA", "url": "https://www.ensembl.org/id/YDL202W_mRNA" }, { "database": "Ensembl Peptide", "id": "YDL202W", "url": "https://www.ensembl.org/id/YDL202W" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 25, "end_pos": 25, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P36521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36521" }, { "database": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ], "site_lbl": "Thr25" } ], "glycation": [], "keywords": [], "publication": [ { "title": "Global analysis of protein localization in budding yeast.", "journal": "Nature", "date": "2003", "authors": "Weissman J.S., Carroll A.S., Howson R.W., Huh W.-K., O'Shea E.K., Falvo J.V., Gerke L.C.", "evidence": [ { "database": "UniProtKB", "id": "P36521", "url": "https://www.uniprot.org/uniprot/P36521" } ], "reference": [ { "type": "PubMed", "id": "14562095", "url": "https://glygen.org/publication/PubMed/14562095" } ] }, { "title": "Global analysis of protein expression in yeast.", "journal": "Nature", "date": "2003", "authors": "Dephoure N., Weissman J.S., Howson R.W., Huh W.-K., O'Shea E.K., Belle A., Bower K., Ghaemmaghami S.", "evidence": [ { "database": "UniProtKB", "id": "P36521", "url": "https://www.uniprot.org/uniprot/P36521" } ], "reference": [ { "type": "PubMed", "id": "14562106", "url": "https://glygen.org/publication/PubMed/14562106" } ] }, { "title": "The proteome of Saccharomyces cerevisiae mitochondria.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2003", "authors": "Sickmann A., Zahedi R.P., Rehling P., Chacinska A., Guiard B., Meyer H.E., Meisinger C., Reinders J., Pfanner N., Joppich C., Perschil I., Schoenfisch B., Wagner Y.", "evidence": [ { "database": "UniProtKB", "id": "P36521", "url": "https://www.uniprot.org/uniprot/P36521" } ], "reference": [ { "type": "PubMed", "id": "14576278", "url": "https://glygen.org/publication/PubMed/14576278" } ] }, { "title": "Extended N-terminal sequencing of proteins of the large ribosomal subunit from yeast mitochondria.", "journal": "FEBS Lett.", "date": "1991", "authors": "Kruft V., Graack H.-R., Goldschmidt-Reisin S., Grohmann L., Kitakawa M., Choli T.", "evidence": [ { "database": "UniProtKB", "id": "P36521", "url": "https://www.uniprot.org/uniprot/P36521" } ], "reference": [ { "type": "PubMed", "id": "2060626", "url": "https://glygen.org/publication/PubMed/2060626" } ] }, { "title": "Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.", "journal": "Science signaling", "date": "2010-12-21", "authors": "Bodenmiller Bernd, Wanka Stefanie, Kraft Claudine, Urban J\u00f6rg, Campbell David, Pedrioli Patrick G, Gerrits Bertran, Picotti Paola, Lam Henry, Vitek Olga, Brusniak Mi-Youn, Roschitzki Bernd, Zhang Chao, Shokat Kevan M, Schlapbach Ralph, Colman-Lerner Alejandro, Nolan Garry P, Nesvizhskii Alexey I, Peter Matthias, Loewith Robbie, von Mering Christian, Aebersold Ruedi", "evidence": [ { "database": "iPTMnet", "id": "P36521", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P36521" } ], "reference": [ { "type": "PubMed", "id": "21177495", "url": "https://glygen.org/publication/PubMed/21177495" } ] }, { "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.", "journal": "G3 (Bethesda)", "date": "2014", "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael", "evidence": [ { "database": "UniProtKB", "id": "P36521", "url": "https://www.uniprot.org/uniprot/P36521" } ], "reference": [ { "type": "PubMed", "id": "24374639", "url": "https://glygen.org/publication/PubMed/24374639" } ] }, { "title": "Structure of the yeast mitochondrial large ribosomal subunit.", "journal": "Science", "date": "2014", "authors": "Brown A., Amunts A., Ramakrishnan V., Scheres S.H., Bai X.C., Murshudov G., Hussain T., Long F., Emsley P., Llacer J.L.", "evidence": [ { "database": "UniProtKB", "id": "P36521", "url": "https://www.uniprot.org/uniprot/P36521" } ], "reference": [ { "type": "PubMed", "id": "24675956", "url": "https://glygen.org/publication/PubMed/24675956" } ] }, { "title": "Organization of the mitochondrial translation machinery studied in situ by cryoelectron tomography.", "journal": "Nat. Commun.", "date": "2015", "authors": "Herrmann J.M., Woellhaf M.W., Pfeffer S., Forster F.", "evidence": [ { "database": "UniProtKB", "id": "P36521", "url": "https://www.uniprot.org/uniprot/P36521" } ], "reference": [ { "type": "PubMed", "id": "25609543", "url": "https://glygen.org/publication/PubMed/25609543" } ] }, { "title": "The nucleotide sequence of a 39 kb segment of yeast chromosome IV: 12 new open reading frames, nine known genes and one gene for Gly-tRNA.", "journal": "Yeast", "date": "1997", "authors": "Bahr A., Hankeln T., Schmidt E.R., Kraemer C., Moeller-Rieker S., Protin U.", "evidence": [ { "database": "UniProtKB", "id": "P36521", "url": "https://www.uniprot.org/uniprot/P36521" } ], "reference": [ { "type": "PubMed", "id": "9046097", "url": "https://glygen.org/publication/PubMed/9046097" } ] }, { "title": "The yeast ORF YDL202w codes for the mitochondrial ribosomal protein YmL11.", "journal": "Curr. Genet.", "date": "1997", "authors": "Schweyen R.J., Jarosch E., Bui D.M.", "evidence": [ { "database": "UniProtKB", "id": "P36521", "url": "https://www.uniprot.org/uniprot/P36521" } ], "reference": [ { "type": "PubMed", "id": "9162110", "url": "https://glygen.org/publication/PubMed/9162110" } ] }, { "title": "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.", "journal": "Nature", "date": "1997", "authors": "Andrews S., Bahr A., Bloecker H., Brandt P., Connor R., Du Z., Fulton L., Gentles S., Hawkins J., Hillier L.W., Johnson D., Latreille P., Mardis E., Mewes H.-W., Miller N., Niblett D., Oliver K., Schaefer M., Scharfe M., Vaudin M., Wambutt R., Waterston R., Wedler H., Wilson R., Chen E., Le T., Verhasselt P., Bowman S., Hunt S., Wagner G., Chung E., Nakahara K., Botstein D., Brueckner M., Davis R.W., Lin D., Hankeln T., Schneider C., Schmidt E.R., Duncan M., Favello A., Kucaba T., Rifkin L., Trevaskis E., Wohldman P., Barrell B.G., Rieger M., Berno A., Schroeder M., Ding H., Oh C., Oefner P., Schwarz S., Woelfl S., Kleine K., Becker A., Prydz H., Cooper J., Arnold W., Eide L.G., Kraemer C., Lashkari D., Allen E., Jimenez A., Kuester H., Hoheisel J.D., Pauley A., Paulin L., Brown D., Jaeger W., Volckaert G., Hyman R.W., Andre B., Perez-Alonso M., Araujo R., Komp C., Lew H., Namath A., Roberts D., Paricio N., Boskovic J., Louis E.J., Mulligan J.T., Delaveau T., Greco T., Johnston L., Nhan M., Jones L., Odell C., Menezes S., Johnston M., Pohl T.M., Harris D.E., Schramm S., McDonald S., Salom D., Bargues M., Cherry J.M., Ballesta J.P.G., Churcher C.M., Dedman K., Dietrich F.S., Dujon B., Goffeau A., Hamlin N., Hani J., Jacq C., Mueller-Auer S., Perea J., Perez-Ortin J.E., Rajandream M.A., Remacha M.A., Revuelta J.L., Vissers S., Walsh S.V., Zollner A., del Rey F., Jonniaux J.-L., Purnelle B., Saiz J.E., Urrestarazu L.A., Voet M., Wilcox L., Albermann K., Alt-Moerbe J., Aviles E., Baron L., Biteau N., Blugeon C., Brinkman R., Buitrago M.J., Carpenter J., Coster F., Garcia-Cantalejo J.M., Gattung S., Gomez-Peris A., Granotier C., Hallsworth K., Hanemann V., Heumann K., Hunicke-Smith S., Jier M., Kirsten J., Laamanen P., Langston Y., Legros Y., Moeller-Rieker S., Monnet A., Moro M., Mosedale D., Murphy L.D., Nussbaumer B., Peluso D., Petel F.X., Rasmussen S.W., Richards C., Riles L., Saluz H.P., Saren A.-M., Scholler P., Shogren T., Shore L., Shroff N., Soler-Mira A., Taich A., Vignati D., Wedler E., Winant A., Yelton M.A., Zaccaria P.", "evidence": [ { "database": "UniProtKB", "id": "P36521", "url": "https://www.uniprot.org/uniprot/P36521" } ], "reference": [ { "type": "PubMed", "id": "9169867", "url": "https://glygen.org/publication/PubMed/9169867" } ] } ], "pathway": [ { "id": "sce:YDL202W", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YDL202W", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { 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