{ "uniprot_canonical_ac": "P35995-1", "uniprot_ac": "P35995", "uniprot_id": "YKW2_YEAST", "mass": { "chemical_mass": 82248.0, "monoisotopic_mass": 82248.0 }, "refseq": { "ac": "NP_012700", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012700" }, "gene_names": [], "protein_names": [ { "name": "Uncharacterized transcriptional regulatory protein YKL222C", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P35995" }, { "name": "uncharacterized protein", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012700", "id": "NP_012700" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P35995", "url": "https://www.uniprot.org/uniprot/P35995" } ], "common_name": "Yeast" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprot/P35995", "locus": {} } ], "crossref": [ { "id": "cd00067", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00067", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12148", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12148", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "853658", "url": "https://www.ncbi.nlm.nih.gov/gene/853658", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "sce:YKL222C", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YKL222C", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YLENLWH", "url": "https://omabrowser.org/oma/group/YLENLWH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "1938572at2759", "url": "http://www.orthodb.org/?query=1938572at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31405", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31405", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31405:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31405:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00172", "url": "http://pfam.xfam.org/family/PF00172", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF04082", "url": "http://pfam.xfam.org/family/PF04082", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_P35995", "url": "http://purl.obolibrary.org/obo/PR_P35995", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_012700", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012700", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "S000001705", "url": "https://www.yeastgenome.org/locus/S000001705", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P35995", "url": "https://www.uniprot.org/uniprot/P35995", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P35995-1", "url": "https://www.uniprot.org/uniprot/P35995-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNTELSQKKKLDRQSRRKPAKSCHFCRVRKLKCDRVRPFCGSCSSRNRKQCEYKENTSAMEDQLRKKYRRCSKLEMARRIEELESQLTKQSQPNIHEGQNPLSNMRYLSSKHNRHILYGPTSYRAILATQTDTFAKYREEIWQVLKLSRNNWKREHHYSTLSEISSIETAPPHSGSPSVIEYLCESLPNYEVLCEYLTDFFASDFYDSYQIVHKEKVLRDLQDCFVKGPRSHKTGQHTIISLNLDSKKNYYKVGVMTAIMCLASHPKEVPEAIEVFHKVLTSFVSAKVFYTERVQFLFLRYLYINVAGLDGGDQSHCIFIHGLTIDTAIHMGLNEDLRRLYLSKNHPIEEIPYLERLWLWILFTDVKISLSTGIPVRINDDFVNKVRLENYSSSGDILLYKTTLRLRNIMKQIHAREKPPDIPLIIEDLKKFTIKMFKPLDFYLNASNLNGNEFTELQLWHATLHMIGSLSNLYTLTHQDFDARIFNFSVLAPLNSLHLCFNVLETYFELDNSKLSSKSLCLSKKWPHLNNALFLIYVNAFRALIQIYTIFLQYMENKDIQLFIQRNSSALTYSICPGDFEGPHNKCISLKIAFKEMENIFDHIHQEKLKPLTQIWQNSYYFSIIISMEKIGRRAFNKGMKNIDEGPETENDATENSLTTILNDLEGPLEDFSENFIDDILGSPSAFFDTAISGWSNFEDFFSR", "length": 705, "header": "sp|P35995-1|YKW2_YEAST Isoform 1 of Uncharacterized transcriptional regulatory protein YKL222C OS=Saccharomyces cerevisiae S288C OX=559292 GN= PE=4 SV=1 CANONICAL=P35995-1" }, "isoforms": [ { "isoform_ac": "P35995-1", "url": "", "sequence": { "sequence": "MKNTELSQKKKLDRQSRRKPAKSCHFCRVRKLKCDRVRPFCGSCSSRNRKQCEYKENTSAMEDQLRKKYRRCSKLEMARRIEELESQLTKQSQPNIHEGQNPLSNMRYLSSKHNRHILYGPTSYRAILATQTDTFAKYREEIWQVLKLSRNNWKREHHYSTLSEISSIETAPPHSGSPSVIEYLCESLPNYEVLCEYLTDFFASDFYDSYQIVHKEKVLRDLQDCFVKGPRSHKTGQHTIISLNLDSKKNYYKVGVMTAIMCLASHPKEVPEAIEVFHKVLTSFVSAKVFYTERVQFLFLRYLYINVAGLDGGDQSHCIFIHGLTIDTAIHMGLNEDLRRLYLSKNHPIEEIPYLERLWLWILFTDVKISLSTGIPVRINDDFVNKVRLENYSSSGDILLYKTTLRLRNIMKQIHAREKPPDIPLIIEDLKKFTIKMFKPLDFYLNASNLNGNEFTELQLWHATLHMIGSLSNLYTLTHQDFDARIFNFSVLAPLNSLHLCFNVLETYFELDNSKLSSKSLCLSKKWPHLNNALFLIYVNAFRALIQIYTIFLQYMENKDIQLFIQRNSSALTYSICPGDFEGPHNKCISLKIAFKEMENIFDHIHQEKLKPLTQIWQNSYYFSIIISMEKIGRRAFNKGMKNIDEGPETENDATENSLTTILNDLEGPLEDFSENFIDDILGSPSAFFDTAISGWSNFEDFFSR", "length": 705, "header": "sp|P35995-1|YKW2_YEAST Isoform 1 of Uncharacterized transcriptional regulatory protein YKL222C OS=Saccharomyces cerevisiae S288C OX=559292 GN= PE=4 SV=1 CANONICAL=P35995-1" }, "locus": { "chromosome": "XI", "start_pos": 5620, "end_pos": 3506, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "YKL222C_mRNA", "url": "https://www.ensembl.org/id/YKL222C_mRNA" }, { "database": "Ensembl Peptide", "id": "YKL222C", "url": "https://www.ensembl.org/id/YKL222C" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.", "journal": "G3 (Bethesda)", "date": "2014", "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael", "evidence": [ { "database": "UniProtKB", "id": "P35995", "url": "https://www.uniprot.org/uniprot/P35995" } ], "reference": [ { "type": "PubMed", "id": "24374639", "url": "https://glygen.org/publication/PubMed/24374639" } ] }, { "title": "Sequencing of a 13.2 kb segment next to the left telomere of yeast chromosome XI revealed five open reading frames and recent recombination events with the right arms of chromosomes III and V.", "journal": "Yeast", "date": "1994", "authors": "Alexandraki D., Tzermia M.", "evidence": [ { "database": "UniProtKB", "id": "P35995", "url": "https://www.uniprot.org/uniprot/P35995" } ], "reference": [ { "type": "PubMed", "id": "8091865", "url": "https://glygen.org/publication/PubMed/8091865" } ] }, { "title": "Complete DNA sequence of yeast chromosome XI.", "journal": "Nature", "date": "1994", "authors": "Ansorge W., Duesterhoeft A., Mewes H.-W., Obermaier B., Wiemann S., Legrain P., Zimmermann J., Xu G., Rose M., Planta R.J., Colleaux L., Rieger M., Fukuhara H., Portetelle D., Mueller S., Becker I., Feldmann H., Kleine K., Gonzalez A., Hewitt N., Schwager C., Voss H., Jimenez A., Erfle H., Jauniaux J.-C., Jacquier A., Dion C., Maia e Silva A., Pallier C., Stegemann J., Andre B., Cheret G., Sor F., Haasemann M., Koetter P., Entian K.-D., Baladron V., Vilela C., Thierry A., Louis E.J., Hollenberg C.P., Marck C., Santos M.A., Soares H., Philippsen P., Poehlmann R., Vandenbol M., Domdey H., Garcia-Ramirez J.J., Pohl T.M., James C.M., Pfeiffer F., Ghazvini M., Ballesta J.P.G., Bossier P., Daignan-Fornier B., Dujon B., Esteban P.F., Fernandes L., Goffeau A., Hegemann J.H., Hilger F., Oliver S.G., Remacha M.A., Revuelta J.L., Rodrigues-Pousada C., Vissers S., del Rey F., van Dyck L., Alexandraki D., Bolotin-Fukuhara M., Duesterhus S., Guerreiro P., Kirchrath L., Purnelle B., Ramezani Rad M., Skala J., Tzermia M., Urrestarazu L.A., Banrevi A., Bolle P.-A., Bou G., Boyer J., Buitrago M.J., Fobo G.M., Fritz C., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Gent M.E., Grothues D., Horaitis O., Indge K.J., Keuchel H., Liebl S., Moestl D., Monnier A.-L., Pascolo S., Pohl F.M., Puzos V., Rasmussen S.W., Richard G.-F., Rupp T., Sensen C., Tettelin H., Valens M., van Vliet-Reedijk J.C., von Wettstein D.", "evidence": [ { "database": "UniProtKB", "id": "P35995", "url": "https://www.uniprot.org/uniprot/P35995" } ], "reference": [ { "type": "PubMed", "id": "8196765", "url": "https://glygen.org/publication/PubMed/8196765" } ] } ], "pathway": [ { "id": "sce:YKL222C", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:YKL222C", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P35995", "url": "https://www.uniprot.org/uniprot/P35995" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "P35995", "url": "https://www.uniprot.org/uniprot/P35995" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P35995", "url": "https://www.uniprot.org/uniprot/P35995" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P35995", "url": "https://www.uniprot.org/uniprot/P35995" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "P35995", "url": "https://www.uniprot.org/uniprot/P35995" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }