{ "uniprot_canonical_ac": "P31325-1", "uniprot_ac": "P31325", "uniprot_id": "PHKG2_RAT", "mass": { "chemical_mass": 46678.0, "monoisotopic_mass": 46678.0 }, "refseq": { "ac": "NP_542151", "name": "phosphorylase b kinase gamma catalytic chain, liver/testis isoform", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_542151" }, "gene_names": [ { "name": "Phkg2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P31325", "id": "P31325" }, { "name": "Phkg2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_542151", "id": "NP_542151" } ], "protein_names": [ { "name": "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P31325" }, { "name": "2.7.11.19", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P31325" }, { "name": "PHK-gamma-LT", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P31325" }, { "name": "PHK-gamma-T; phosphorylase kinase subunit gamma-2; phosphorylase kinase gamma subunit 2; serine/threonine-protein kinase PHKG2; PHK-gamma-LT; phosphorylase kinase, gamma 2 (testis)", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_542151", "id": "NP_542151" }, { "name": "PHK-gamma-T", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P31325" }, { "name": "Phosphorylase kinase subunit gamma-2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P31325" }, { "name": "phosphorylase b kinase gamma catalytic chain, liver/testis isoform", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_542151", "id": "NP_542151" } ], "function": [ { "annotation": "Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM.", "evidence": [ { "database": "UniProtKB", "id": "P31325", "url": "https://www.uniprot.org/uniprot/P31325#function" }, { "database": "PubMed", "id": "1370475", "url": "https://glygen.org/publication/PubMed/1370475" } ] } ], "disease": [ { "disease_id": "DOID:0111043", "recommended_name": { "id": "DOID:0111043", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111043", "name": "glycogen storage disease IXc", "description": "A glycogen storage disease IX characterized by autosomal recessive inheritance of hepatomegaly, hypotonia, growth retardation, and liver dysfunction with onset in childhood and improvement of symptoms with age that has_material_basis_in homozygous and compound heterozygous mutation in the PHKG2 gene on chromosome 16p11." }, "synonyms": [ { "id": "DOID:0111043", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111043", "name": "GSD type 9C", "description": "" }, { "id": "DOID:0111043", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111043", "name": "GSD type IXc", "description": "" }, { "id": "DOID:0111043", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111043", "name": "GSD9C", "description": "" }, { "id": "DOID:0111043", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111043", "name": "glycogen storage disease type 9C", "description": "" }, { "id": "DOID:0111043", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111043", "name": "glycogen storage disease type IXc", "description": "" }, { "id": "DOID:0111043", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111043", "name": "glycogenosis type 9C", "description": "" }, { "id": "DOID:0111043", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0111043", "name": "glycogenosis type IXc", "description": "" }, { "id": "MONDO:0013091", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013091", "name": "glycogen storage disease IXc", "description": "A liver PhK deficiency caused by variants in the PHKG2 gene" }, { "id": "MONDO:0013091", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013091", "name": "GSD type 9C", "description": "" }, { "id": "MONDO:0013091", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013091", "name": "GSD type IXc", "description": "" }, { "id": "MONDO:0013091", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013091", "name": "GSD9C", "description": "" }, { "id": "MONDO:0013091", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013091", "name": "PHKG2 glycogen storage disease", "description": "" }, { "id": "MONDO:0013091", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013091", "name": "PHKG2-related glycogen storage disease type IX", "description": "" }, { "id": "MONDO:0013091", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013091", "name": "glycogen storage disease IXc", "description": "" }, { "id": "MONDO:0013091", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013091", "name": "glycogen storage disease caused by mutation in PHKG2", "description": "" }, { "id": "MONDO:0013091", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013091", "name": "glycogen storage disease type IXc", "description": "" }, { "id": "MONDO:0013091", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013091", "name": "GSD IXc", "description": "" }, { "id": "MIM:613027", "resource": "MIM", "url": "https://www.omim.org/entry/613027", "name": "Glycogen storage disease 9C", "description": "Glycogen storage disease 9C" } ], "evidence": [ { "id": "0111043", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0111043" } ] }, { "disease_id": "DOID:2747", "recommended_name": { "id": "DOID:2747", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:2747", "name": "glycogen storage disease", "description": "A glycogen metabolism disorder that has_material_basis_in enzymes deficiencies necessary in the processing of glycogen synthesis or breakdown within muscles, liver, and other cell types." }, "synonyms": [ { "id": "DOID:2747", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:2747", "name": "glycogenosis", "description": "" } ], "evidence": [ { "id": "2747", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:2747" } ] }, { "disease_id": "DOID:5082", "recommended_name": { "id": "DOID:5082", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5082", "name": "liver cirrhosis", "description": "" }, "synonyms": [ { "id": "DOID:5082", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5082", "name": "Cirrhosis", "description": "" }, { "id": "DOID:5082", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5082", "name": "cirrhosis of liver", "description": "" }, { "id": "MONDO:0005155", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005155", "name": "cirrhosis of liver", "description": "A disorder characterized by replacement of the liver parenchyma with fibrous tissue and regenerative nodules. It is usually caused by alcoholism, hepatitis B, and hepatitis C. Complications include the development of ascites, esophageal varices, bleeding, and hepatic encephalopathy." }, { "id": "MONDO:0005155", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005155", "name": "cirrhosis", "description": "" }, { "id": "MONDO:0005155", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005155", "name": "cirrhosis of liver", "description": "" }, { "id": "MONDO:0005155", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005155", "name": "liver cirrhosis", "description": "" } ], "evidence": [ { "id": "5082", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "P31325", "url": "https://www.uniprot.org/uniprot/P31325" } ], "common_name": "Rat" } ], "gene": [ { "name": "Phkg2", "url": "https://www.uniprot.org/uniprot/P31325", "locus": { "chromosome": "1", "start_pos": 182197124, "end_pos": 182184650, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000018725", "url": "https://www.ensembl.org/id/ENSRNOG00000018725" } ] } } ], "crossref": [ { "id": "ENSRNOG00000018725", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000018725", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "2.7.11.19", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.19&UniProtAcc=P31325", "database": "BRENDA", "categories": [ "Enzyme and Pathway" ] }, { "id": "cd14181", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14181", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "140671", "url": "https://www.ncbi.nlm.nih.gov/gene/140671", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:140671", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:140671", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QFRSPEW", "url": "https://omabrowser.org/oma/group/QFRSPEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "1121238at2759", "url": "http://www.orthodb.org/?query=1121238at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24347:SF390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24347:SF390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "http://pfam.xfam.org/family/PF00069", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_P31325", "url": "http://purl.obolibrary.org/obo/PR_P31325", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-RNO-70221", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-70221", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_542151", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_542151", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "620024", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=620024", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "P31325", "url": "https://www.uniprot.org/uniprot/P31325", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P31325-1", "url": "https://www.uniprot.org/uniprot/P31325-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLDVGPEDELPDWAAAKEFYQKYDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVNFLHVNNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSNTVKDLIAKLLQVDPNARLTAEQALQHPFFERCKGSQPWNLTPRQRFRVAVWTILAAGRVALSSHRLRPLTKNALLRDPYALRPVRRLIDNCAFRLYGHWVKKGEQQNRAALFQHQPPRPFPIIATDLEGDSSAITEDEVTLVRS", "length": 406, "header": "sp|P31325-1|PHKG2_RAT Isoform 1 of Phosphorylase b kinase gamma catalytic chain, liver/testis isoform OS=Rattus norvegicus OX=10116 GN=Phkg2 PE=1 SV=1 CANONICAL=P31325-1" }, "isoforms": [ { "isoform_ac": "P31325-1", "url": "", "sequence": { "sequence": "MTLDVGPEDELPDWAAAKEFYQKYDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVNFLHVNNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSNTVKDLIAKLLQVDPNARLTAEQALQHPFFERCKGSQPWNLTPRQRFRVAVWTILAAGRVALSSHRLRPLTKNALLRDPYALRPVRRLIDNCAFRLYGHWVKKGEQQNRAALFQHQPPRPFPIIATDLEGDSSAITEDEVTLVRS", "length": 406, "header": "sp|P31325-1|PHKG2_RAT Isoform 1 of Phosphorylase b kinase gamma catalytic chain, liver/testis isoform OS=Rattus norvegicus OX=10116 GN=Phkg2 PE=1 SV=1 CANONICAL=P31325-1" }, "locus": { "chromosome": "1", "start_pos": 182196837, "end_pos": 182184927, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000087142", "url": "https://www.ensembl.org/id/ENSRNOT00000087142" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000072734", "url": "https://www.ensembl.org/id/ENSRNOP00000072734" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Molecular cloning and enzymatic analysis of the rat homolog of 'PhK-gamma T,' an isoform of phosphorylase kinase catalytic subunit.", "journal": "J. Biol. Chem.", "date": "1992", "authors": "Hanks S.K., Calalb M.B., Fox D.T.", "evidence": [ { "database": "UniProtKB", "id": "P31325", "url": "https://www.uniprot.org/uniprot/P31325" } ], "reference": [ { "type": "PubMed", "id": "1370475", "url": "https://glygen.org/publication/PubMed/1370475" } ] } ], "pathway": [ { "id": "rno:140671", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:140671", "resource": "KEGG Pathway" }, { "id": "R-RNO-70221", "name": "Glycogen breakdown (glycogenolysis)", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-70221", "resource": "Reactome", "description": "Glycogen breakdown (glycogenolysis)" } ], "orthologs": [ { "uniprot_canonical_ac": "P15735-1", "protein_name": "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform", "gene_name": "PHKG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPWNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG", "length": 406 }, "evidence": [ { "id": "45232665", "url": "http://www.informatics.jax.org/homology/45232665", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DB30-1", "protein_name": "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform", "gene_name": "Phkg2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTLDVGPEDELPDWAAAKEFYQKYDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEAGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFTSPEWDDRSNTVKDLISKLLQVDPEARLTAEQALQHPFFERCEGSQPWNLTPRQRFRVAVWTILAAGRVALSSHRLRPLTKNALLRDPYALRPVRRLIDNCAFRLYGHWVKKGEQQNRAALFQHQPPRLFPIAATELEGDSGAITEDEATLVRS", "length": 406 }, "evidence": [ { "id": "45232665", "url": "http://www.informatics.jax.org/homology/45232665", "database": "MGI" }, { "id": "P31325", "url": "https://omabrowser.org/oma/group/P31325/", "database": "OMA" } ], "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "phosphorylase kinase activity", "id": "GO:0004689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004689", "evidence": [ { "database": "UniProtKB", "id": "P31325", "url": "https://www.uniprot.org/uniprot/P31325" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "P31325", "url": "https://www.uniprot.org/uniprot/P31325" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P31325", "url": "https://www.uniprot.org/uniprot/P31325" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "P31325", "url": "https://www.uniprot.org/uniprot/P31325" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "phosphorylase kinase complex", "id": "GO:0005964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005964", "evidence": [ { "database": "UniProtKB", "id": "P31325", "url": "https://www.uniprot.org/uniprot/P31325" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P31325", "url": "https://www.uniprot.org/uniprot/P31325" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "P31325", "url": "https://www.uniprot.org/uniprot/P31325" } ], "pmid": "" }, { "name": "glycogen metabolic process", "id": "GO:0005977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005977", "evidence": [ { "database": "UniProtKB", "id": "P31325", "url": "https://www.uniprot.org/uniprot/P31325" } ], "pmid": "" }, { "name": "glycogen biosynthetic process", "id": "GO:0005978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005978", "evidence": [ { "database": "UniProtKB", "id": "P31325", "url": "https://www.uniprot.org/uniprot/P31325" } ], "pmid": "" }, { "name": "glycogen catabolic process", "id": "GO:0005980", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005980", "evidence": [ { "database": "UniProtKB", "id": "P31325", "url": "https://www.uniprot.org/uniprot/P31325" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-RNO-71588", "name": "glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P09811-1", "P31325-1" ], "evidence": [ { "id": "R-RNO-71588", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-71588" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "P09811", "gene_name": "Pygl", "activity": [ { "ec_number": "2.4.1.1", "activity": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.", "evidence": [ { "id": "P09811", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09811" } ] }, { "ec_number": "2.4.1.1", "activity": "", "evidence": [ { "id": "P09811", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09811" } ] } ] }, { "uniprot_ac": "P31325", "gene_name": "Phkg2", "activity": [ { "ec_number": "2.7.11.19", "activity": "2 ATP + phosphorylase b = 2 ADP + phosphorylase a.", "evidence": [ { "id": "P31325", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31325" } ] }, { "ec_number": "2.7.11.19", "activity": "", "evidence": [ { "id": "P31325", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P31325" } ] } ] } ], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }