{
    "uniprot_canonical_ac": "P20786-1",
    "uniprot_ac": "P20786",
    "uniprot_id": "PGFRA_RAT",
    "mass": {
        "chemical_mass": 122642.0,
        "monoisotopic_mass": 122642.0
    },
    "refseq": {
        "ac": "NP_036934",
        "name": "platelet-derived growth factor receptor alpha precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036934"
    },
    "gene_names": [
        {
            "name": "Pdgfra",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/P20786",
            "id": "P20786"
        },
        {
            "name": "APDGFR; PDGFACE",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036934",
            "id": "NP_036934"
        },
        {
            "name": "Pdgfra",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036934",
            "id": "NP_036934"
        }
    ],
    "protein_names": [
        {
            "name": "Platelet-derived growth factor receptor alpha",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "P20786"
        },
        {
            "name": "2.7.10.1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P20786"
        },
        {
            "name": "Alpha platelet-derived growth factor receptor",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P20786"
        },
        {
            "name": "Alpha-type platelet-derived growth factor receptor",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P20786"
        },
        {
            "name": "CD140 antigen-like family member A",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P20786"
        },
        {
            "name": "PDGF-R-alpha",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P20786"
        },
        {
            "name": "PDGFR-alpha",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P20786"
        },
        {
            "name": "Platelet-derived growth factor alpha receptor",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P20786"
        },
        {
            "name": "alpha-type platelet-derived growth factor receptor; PDGF-R-alpha; CD140 antigen-like family member A; PDGFR-alpha; alpha platelet-derived growth factor receptor; platelet-derived growth factor alpha receptor; platelet-derived growth factor receptor alpha-like; platelet derived growth factor receptor, alpha polypeptide",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036934",
            "id": "NP_036934"
        },
        {
            "name": "platelet-derived growth factor receptor alpha precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036934",
            "id": "NP_036934"
        }
    ],
    "function": [
        {
            "annotation": "CSN6 mediates PDGF-induced pulmonary arterial smooth muscle cells proliferation.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_036934",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036934"
                },
                {
                    "database": "PubMed",
                    "id": "30180991",
                    "url": "https://glygen.org/publication/PubMed/30180991"
                }
            ]
        },
        {
            "annotation": "PDGFs could exert their mechanism of action through an autocrine/paracrine effect on granulosa and theca cells mediated by PDGFRs.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_036934",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036934"
                },
                {
                    "database": "PubMed",
                    "id": "25937181",
                    "url": "https://glygen.org/publication/PubMed/25937181"
                }
            ]
        },
        {
            "annotation": "STAT3 overexpression in corpus cavernosum smooth muscle in rats weakened the suppressive effect of PDGFR inhibition on the morphology and phenotypic transformation induced by PDGF-BB Publication Status: Online-Only",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_036934",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036934"
                },
                {
                    "database": "PubMed",
                    "id": "28245285",
                    "url": "https://glygen.org/publication/PubMed/28245285"
                }
            ]
        },
        {
            "annotation": "Treatment with different concentrations of PDGF increased the levels of phosphorylated protein kinase B (AKT), beta-catenin, and Cx43, whereas inhibition of PDGFR or activation of phosphatidylinositol 3 kinase (PI3K)/AKT signaling altered b-catenin and Cx43 expression.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_036934",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036934"
                },
                {
                    "database": "PubMed",
                    "id": "29174980",
                    "url": "https://glygen.org/publication/PubMed/29174980"
                }
            ]
        },
        {
            "annotation": "Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "G3V6A0",
                    "url": "https://www.uniprot.org/uniprot/G3V6A0#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "PIRNR500950",
                    "url": "https://www.uniprot.org/uniprot/PIRNR500950#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "P20786",
                    "url": "https://www.uniprot.org/uniprot/P20786#function"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0050902",
            "recommended_name": {
                "id": "DOID:0050902",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050902",
                "name": "medulloblastoma",
                "description": "An infratentorial cancer that is located_in the lower part of the brain and is a type of primitive neuroectodermal tumor."
            },
            "synonyms": [
                {
                    "id": "DOID:0050902",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050902",
                    "name": "CNS PNET",
                    "description": ""
                },
                {
                    "id": "DOID:0050902",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050902",
                    "name": "CPNET",
                    "description": ""
                },
                {
                    "id": "DOID:0050902",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050902",
                    "name": "brain medulloblastoma",
                    "description": ""
                },
                {
                    "id": "DOID:0050902",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050902",
                    "name": "infratentorial primitive neuroectodermal tumor",
                    "description": ""
                },
                {
                    "id": "DOID:0050902",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050902",
                    "name": "localized primitive neuroectodermal tumor",
                    "description": ""
                },
                {
                    "id": "DOID:0050902",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050902",
                    "name": "Medulloblastoma, histologically defined",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastoma",
                    "description": "A malignant, invasive embryonal neoplasm arising from the cerebellum. It occurs predominantly in children and has the tendency to metastasize via the cerebrospinal fluid pathways. Signs and symptoms include truncal ataxia, disturbed gait, lethargy, headache, and vomiting. There are four histologic variants: classic medulloblastoma, large cell/anaplastic medulloblastoma, desmoplastic/nodular medulloblastoma, and medulloblastoma with extensive nodularity."
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "brain medulloblastoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "cerebellar medulloblastoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "cerebellum embryonal neoplasm",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastoma",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastoma, autosomal recessive, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastoma, desmoplastic, autosomal recessive, autosomal dominant, somatic mutation",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastoma, malignant",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastoma, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastomas",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "CNS PNET",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "CPNET",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "MDB",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "infratentorial primitive neuroectodermal tumor",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "infratentorial primitive neuroectodermal tumour",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "localised primitive neuroectodermal tumour",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "localized primitive neuroectodermal tumor",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastoma with extensive nodularity",
                    "description": ""
                },
                {
                    "id": "MONDO:0007959",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007959",
                    "name": "medulloblastoma, desmoplastic",
                    "description": ""
                },
                {
                    "id": "MIM:155255",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/155255",
                    "name": "Medulloblastoma",
                    "description": "Medulloblastoma"
                }
            ],
            "evidence": [
                {
                    "id": "0050902",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050902"
                }
            ]
        },
        {
            "disease_id": "DOID:10763",
            "recommended_name": {
                "id": "DOID:10763",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:10763",
                "name": "hypertension",
                "description": "An artery disease characterized by chronic elevated blood pressure in the arteries."
            },
            "synonyms": [
                {
                    "id": "DOID:10763",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10763",
                    "name": "HTN",
                    "description": ""
                },
                {
                    "id": "DOID:10763",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10763",
                    "name": "hyperpiesia",
                    "description": ""
                },
                {
                    "id": "DOID:10763",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10763",
                    "name": "vascular hypertensive disorder",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "10763",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:10763"
                }
            ]
        },
        {
            "disease_id": "DOID:11446",
            "recommended_name": {
                "id": "DOID:11446",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:11446",
                "name": "sciatic neuropathy",
                "description": ""
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "11446",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:11446"
                }
            ]
        },
        {
            "disease_id": "DOID:12215",
            "recommended_name": {
                "id": "DOID:12215",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:12215",
                "name": "oligohydramnios",
                "description": "A placenta disease that is characterized by a deficiency of amniotic fluid sometimes resulting in an embryonic defect through adherence between embryo and amnion."
            },
            "synonyms": [
                {
                    "id": "DOID:12215",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:12215",
                    "name": "Oligohydramnios - delivered",
                    "description": ""
                },
                {
                    "id": "DOID:12215",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:12215",
                    "name": "antepartum oligohydramnios",
                    "description": ""
                },
                {
                    "id": "DOID:12215",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:12215",
                    "name": "delivered oligohydramnios",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "12215",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:12215"
                }
            ]
        },
        {
            "disease_id": "DOID:1240",
            "recommended_name": {
                "id": "DOID:1240",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:1240",
                "name": "leukemia",
                "description": "A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "1240",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:1240"
                }
            ]
        },
        {
            "disease_id": "DOID:162",
            "recommended_name": {
                "id": "DOID:162",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:162",
                "name": "cancer",
                "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis."
            },
            "synonyms": [
                {
                    "id": "DOID:162",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:162",
                    "name": "malignant neoplasm",
                    "description": ""
                },
                {
                    "id": "DOID:162",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:162",
                    "name": "malignant tumor",
                    "description": ""
                },
                {
                    "id": "DOID:162",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:162",
                    "name": "primary cancer",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "162",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:162"
                }
            ]
        },
        {
            "disease_id": "DOID:1793",
            "recommended_name": {
                "id": "DOID:1793",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:1793",
                "name": "pancreatic cancer",
                "description": "An endocrine gland cancer located_in the pancreas."
            },
            "synonyms": [
                {
                    "id": "DOID:1793",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1793",
                    "name": "Ca body of pancreas",
                    "description": ""
                },
                {
                    "id": "DOID:1793",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1793",
                    "name": "Ca head of pancreas",
                    "description": ""
                },
                {
                    "id": "DOID:1793",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1793",
                    "name": "Ca tail of pancreas",
                    "description": ""
                },
                {
                    "id": "DOID:1793",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1793",
                    "name": "malignant neoplasm of body of pancreas",
                    "description": ""
                },
                {
                    "id": "DOID:1793",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1793",
                    "name": "malignant neoplasm of head of pancreas",
                    "description": ""
                },
                {
                    "id": "DOID:1793",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1793",
                    "name": "malignant neoplasm of tail of pancreas",
                    "description": ""
                },
                {
                    "id": "DOID:1793",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1793",
                    "name": "pancreas neoplasm",
                    "description": ""
                },
                {
                    "id": "DOID:1793",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1793",
                    "name": "pancreatic neoplasm",
                    "description": ""
                },
                {
                    "id": "DOID:1793",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1793",
                    "name": "pancreatic tumor",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "1793",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:1793"
                }
            ]
        },
        {
            "disease_id": "DOID:2526",
            "recommended_name": {
                "id": "DOID:2526",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:2526",
                "name": "prostate adenocarcinoma",
                "description": "A prostate carcinoma that derives_from epithelial cells of glandular origin."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "2526",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:2526"
                }
            ]
        },
        {
            "disease_id": "DOID:2696",
            "recommended_name": {
                "id": "DOID:2696",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:2696",
                "name": "Leydig cell tumor",
                "description": "A sex cord-gonadal stromal tumor that secretes testosterone characterized by excessive proliferation of Leydig cells located_in ovary or testicle."
            },
            "synonyms": [
                {
                    "id": "DOID:2696",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:2696",
                    "name": "Leydig cell neoplasm",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "2696",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:2696"
                }
            ]
        },
        {
            "disease_id": "DOID:305",
            "recommended_name": {
                "id": "DOID:305",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:305",
                "name": "carcinoma",
                "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells."
            },
            "synonyms": [
                {
                    "id": "DOID:305",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:305",
                    "name": "epithelial cancer",
                    "description": ""
                },
                {
                    "id": "DOID:305",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:305",
                    "name": "epithelioma",
                    "description": ""
                },
                {
                    "id": "DOID:305",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:305",
                    "name": "malignant Epithelioma",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "305",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:305"
                }
            ]
        },
        {
            "disease_id": "DOID:3459",
            "recommended_name": {
                "id": "DOID:3459",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:3459",
                "name": "breast carcinoma",
                "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells."
            },
            "synonyms": [
                {
                    "id": "DOID:3459",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3459",
                    "name": "Mammary carcinoma",
                    "description": ""
                },
                {
                    "id": "DOID:3459",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3459",
                    "name": "carcinoma of breast",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "3459",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:3459"
                }
            ]
        },
        {
            "disease_id": "DOID:3525",
            "recommended_name": {
                "id": "DOID:3525",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:3525",
                "name": "middle cerebral artery infarction",
                "description": ""
            },
            "synonyms": [],
            "evidence": [
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                    "id": "3525",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:3525"
                }
            ]
        },
        {
            "disease_id": "DOID:3770",
            "recommended_name": {
                "id": "DOID:3770",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:3770",
                "name": "pulmonary fibrosis",
                "description": "An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation."
            },
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                {
                    "id": "DOID:3770",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3770",
                    "name": "Fibrosis of lung",
                    "description": ""
                }
            ],
            "evidence": [
                {
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                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:3770"
                }
            ]
        },
        {
            "disease_id": "DOID:3827",
            "recommended_name": {
                "id": "DOID:3827",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:3827",
                "name": "congenital diaphragmatic hernia",
                "description": "A diaphragm disease characterized by the lack of development of all or part of the diaphragm, which results in an abnormal opening that allows the stomach and intestines to move into the chest cavity and crowd the heart and lungs."
            },
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                    "id": "DOID:3827",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3827",
                    "name": "Diaphragmatic Hernia",
                    "description": ""
                },
                {
                    "id": "MONDO:0007719",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007719",
                    "name": "diaphragmatic hernia 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007719",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007719",
                    "name": "diaphragmatic hernia, congenital 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007719",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007719",
                    "name": "hernia, congenital diaphragmatic 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007719",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007719",
                    "name": "DIH1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007719",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007719",
                    "name": "diaphragm, complete agenesis of",
                    "description": ""
                },
                {
                    "id": "MONDO:0007719",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007719",
                    "name": "diaphragm, unilateral agenesis of",
                    "description": ""
                },
                {
                    "id": "MONDO:0007719",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007719",
                    "name": "diaphragmatic defect, congenital",
                    "description": ""
                },
                {
                    "id": "MONDO:0007719",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007719",
                    "name": "diaphragmatic hernia, congenital",
                    "description": ""
                },
                {
                    "id": "MONDO:0007719",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007719",
                    "name": "hemidiaphragm, agenesis of",
                    "description": ""
                },
                {
                    "id": "MONDO:0007719",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007719",
                    "name": "hernia, congenital diaphragmatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0009103",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009103",
                    "name": "diaphragmatic hernia 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0009103",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009103",
                    "name": "diaphragmatic hernia 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0009103",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009103",
                    "name": "hernia, congenital diaphragmatic 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0009103",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009103",
                    "name": "DIH2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012431",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012431",
                    "name": "diaphragmatic hernia 3",
                    "description": "Any congenital diaphragmatic hernia in which the cause of the disease is a mutation in the ZFPM2 gene."
                },
                {
                    "id": "MONDO:0012431",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012431",
                    "name": "ZFPM2 congenital diaphragmatic hernia",
                    "description": ""
                },
                {
                    "id": "MONDO:0012431",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012431",
                    "name": "congenital diaphragmatic hernia caused by mutation in ZFPM2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012431",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012431",
                    "name": "diaphragmatic hernia 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012431",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012431",
                    "name": "diaphragmatic hernia type 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012431",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012431",
                    "name": "DIH3",
                    "description": ""
                },
                {
                    "id": "MIM:610187",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/610187",
                    "name": "Diaphragmatic hernia 3",
                    "description": "Diaphragmatic hernia 3"
                }
            ],
            "evidence": [
                {
                    "id": "3827",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:3827"
                }
            ]
        },
        {
            "disease_id": "DOID:3840",
            "recommended_name": {
                "id": "DOID:3840",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:3840",
                "name": "craniopharyngioma",
                "description": ""
            },
            "synonyms": [
                {
                    "id": "DOID:3840",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3840",
                    "name": "neoplasm of Rathke's Pouch",
                    "description": ""
                }
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                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:3840"
                }
            ]
        },
        {
            "disease_id": "DOID:4202",
            "recommended_name": {
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                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:4202",
                "name": "brain stem glioma",
                "description": "A brain stem cancer that is characterized by mass lesion of the brainstem, associated cranial nerve nuclei and long tracts, has_material_basis_in abnormally proliferating cells, derives_from glial cells."
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                    "id": "DOID:4202",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:4202",
                    "name": "Brainstem Neuroglial tumor",
                    "description": ""
                }
            ],
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                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:4202"
                }
            ]
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        {
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            "recommended_name": {
                "id": "DOID:4440",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:4440",
                "name": "seminoma",
                "description": "A germinoma that has_material_basis_in cells that make sperm and eggs."
            },
            "synonyms": [
                {
                    "id": "DOID:4440",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:4440",
                    "name": "Seminoma, Pure",
                    "description": ""
                }
            ],
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                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:4440"
                }
            ]
        },
        {
            "disease_id": "DOID:4450",
            "recommended_name": {
                "id": "DOID:4450",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:4450",
                "name": "renal cell carcinoma",
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:4450",
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                    "description": ""
                },
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                    "id": "DOID:4450",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:4450",
                    "name": "adenocarcinoma of kidney",
                    "description": ""
                },
                {
                    "id": "DOID:4450",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:4450",
                    "name": "hypernephroma",
                    "description": ""
                },
                {
                    "id": "MONDO:0010456",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010456",
                    "name": "renal cell carcinoma, Xp11-associated",
                    "description": ""
                },
                {
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                    "resource": "MONDO",
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                    "name": "renal cell carcinoma, Xp11-associated",
                    "description": ""
                },
                {
                    "id": "MONDO:0010456",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010456",
                    "name": "renal cell carcinoma, papillary, 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010456",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010456",
                    "name": "RCCX1",
                    "description": ""
                }
            ],
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                }
            ]
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            "recommended_name": {
                "id": "DOID:5603",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:5603",
                "name": "T-cell acute lymphoblastic leukemia",
                "description": "An acute lymphoblastic leukemia that is characterized by too many T-cell lymphoblasts found in the bone marrow and blood."
            },
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5603",
                    "name": "T-cell leukemia",
                    "description": ""
                },
                {
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5603",
                    "name": "acute T cell leukemia",
                    "description": ""
                },
                {
                    "id": "DOID:5603",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5603",
                    "name": "precursor T-lymphoblastic lymphoma/leukemia",
                    "description": ""
                },
                {
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5603",
                    "name": "Precursor T Lymphoblastic Leukemia",
                    "description": ""
                },
                {
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5603",
                    "name": "T Acute Lymphoblastic Leukemia",
                    "description": ""
                },
                {
                    "id": "DOID:5603",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5603",
                    "name": "T-cell acute lymphocytic leukaemia",
                    "description": ""
                },
                {
                    "id": "DOID:5603",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5603",
                    "name": "T-cell lymphoblastic leukemia/lymphoma",
                    "description": ""
                }
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                }
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                "description": ""
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                    "url": "http://disease-ontology.org/term/DOID:8549",
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                    "resource": "Disease Ontology",
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                    "name": "Indolent ulcer",
                    "description": ""
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:8683",
                    "name": "Chloroma",
                    "description": ""
                },
                {
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:8683",
                    "name": "Extramedullary Myeloid tumor",
                    "description": ""
                },
                {
                    "id": "DOID:8683",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:8683",
                    "name": "Granulocytic sarcoma",
                    "description": ""
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                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:8683"
                }
            ]
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        {
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            "recommended_name": {
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                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:8692",
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:8692",
                    "name": "Non-Lymphocytic Leukemia",
                    "description": ""
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:8692",
                    "name": "leukaemia myelogenous",
                    "description": ""
                },
                {
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:8692",
                    "name": "leukemia myelogenous",
                    "description": ""
                },
                {
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:8692",
                    "name": "myeloid granulocytic leukaemia",
                    "description": ""
                },
                {
                    "id": "DOID:8692",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:8692",
                    "name": "myeloid granulocytic leukemia",
                    "description": ""
                },
                {
                    "id": "DOID:8692",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:8692",
                    "name": "myeloid leukaemia",
                    "description": ""
                }
            ],
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                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:8692"
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            ]
        },
        {
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            "recommended_name": {
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                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:8719",
                "name": "in situ carcinoma",
                "description": "A carcinoma that is an early development defined by the absence of invasion of surrounding tissues."
            },
            "synonyms": [],
            "evidence": [
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                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:8719"
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            ]
        },
        {
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                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:999",
                "name": "hypereosinophilic syndrome",
                "description": "A leukocyte disease that is characterized by high numbers of eosinophils which over time enter various tissues, eventually damaging organs."
            },
            "synonyms": [
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:999",
                    "name": "Eosinophilic leukocytosis",
                    "description": ""
                },
                {
                    "id": "DOID:999",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:999",
                    "name": "eosinophilia",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "999",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:999"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
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                {
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                    "url": "https://www.uniprot.org/uniprot/P20786"
                }
            ],
            "common_name": "Rat"
        }
    ],
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                "start_pos": 33005839,
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        }
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            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "CHEMBL2111344",
            "url": "https://www.ebi.ac.uk/chembldb/target/inspect/CHEMBL2111344",
            "database": "ChEMBL",
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        {
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            "database": "IntAct",
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        },
        {
            "id": "IPR000719",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001245",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001824",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001824",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR003598",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR003599",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR007110",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR008266",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR008266",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR011009",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013098",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013783",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR017441",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR020635",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR020635",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR027290",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR027290",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036179",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:25267",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:25267",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "PGLILCQ",
            "url": "https://omabrowser.org/oma/group/PGLILCQ/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1614410at2759",
            "url": "http://www.orthodb.org/?query=1614410at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24416",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24416",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24416:SF52",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24416:SF52",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF07679",
            "url": "http://pfam.xfam.org/family/PF07679",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF07714",
            "url": "http://pfam.xfam.org/family/PF07714",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_P20786",
            "url": "http://purl.obolibrary.org/obo/PR_P20786",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-RNO-1257604",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-1257604",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-186763",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-186763",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-186797",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-186797",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-5673001",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5673001",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-6811558",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6811558",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_036934",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036934",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "3284",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=3284",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "10596",
            "url": "https://www.rhea-db.org/rhea/10596",
            "database": "Rhea",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "A0A8I5ZST9",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZST9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5ZST9-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZST9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G3V6A0",
            "url": "https://www.uniprot.org/uniprot/G3V6A0",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G3V6A0-1",
            "url": "https://www.uniprot.org/uniprot/G3V6A0-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P20786",
            "url": "https://www.uniprot.org/uniprot/P20786",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P20786-1",
            "url": "https://www.uniprot.org/uniprot/P20786-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MGTSQAFLVLSCLLTGPSLIVCQLLLPSILPNENEKIVPLSSSFSLRCFGESEVSWQHPMSEEEDPNVEIRTEENNSSLFVTVLEVVNASAAHTGWYTCYYNHTQTEESEIEGRHIYIYVPDPDMAFVPLGMTDSLVIVEEDDSAIIPCLTTDPDTEVTLHNNGRLVPASYDSRQGFNGTFSVGPYICEATVRGRTFKTSEFNVYALKATSELNLEMDTRQTVYKAGETIVVTCAVFNNEVVDLQWTYPGEVRNKGITMLEEIKLPSIKLVYTLTVPKATVKDSGDYECAARQATKEVKEMKTVTISVHEKGFVQIRPTFGHLETVNLHQVREFVVEVQAYPTPRISWLKDNLTLIENLTEITTDVQRSQETRYQSKLKLIRAKEEDSGHYTIIVQNDDDMKSYTFELSTLVPASILELVDDHHGSGGGQTVRCTAEGTPLPNIEWMICKDIKKCNNDTSWTVLASNVSNIITEFHQRGRSTVEGRVSFAKVEETIAVRCLAKNDLGIGNRELKLVAPSLRSELTVAAAVLVLLVIVIVSLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFMSRHPEKPKKDLDIFGLNPADESTRSYVILSFENNGDYVDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEAKNLLSDDDSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGVLLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKEWEGGLDEQRLSADSGYIIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL",
        "length": 1088,
        "header": "sp|P20786-1|PGFRA_RAT Isoform 1 of Platelet-derived growth factor receptor alpha  OS=Rattus norvegicus OX=10116 GN=Pdgfra PE=1 SV=2 CANONICAL=P20786-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A8I5ZST9-1",
            "url": "",
            "sequence": {
                "sequence": "FTVCQGYMVRPWPSLIVCQLLLPSILPNENEKIVPLSSSFSLRCFGESEVSWQHPMSEEEDPNVEIRTEENNSSLFVTVLEVVNASAAHTGWYTCYYNHTQTEESEIEGRHIYIYVPDPDMAFVPLGMTDSLVIVEEDDSAIIPCRTTDPDTEVTLHNNGRLVPASYDSRQGFNGTFSVGPYICEATVRGRTFKTSEFNVYALKATSELNLEMDTRQTVYKAGETIVVTCAVFNNEVVDLQWTYPGEVRNKGITMLEEIKLPSIKLVYTLTVPKATVKDSGDYECAARQATKEVKEMKTVTISVHEKGFVQIRPTFGHLETVNLHQVREFVVEVQAYPTPRISWLKDNLTLIENLTEITTDVQRSQETRYQSKLKLIRAKEEDSGHYTIIVQNDDDMKSYTFELSTLVPASILELVDDHHGSGGGQTVRCTAEGTPLPNIEWMICKDIKKCNNDTSWTVLASNVSNIITEFHQRGRSTVEGRVSFAKVEETIAVRCLAKNDLGIGNRELKLVAPTLRSELTVAAAVLVLLVIVIVSLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFMSRHPEKPKKDLDIFGLNPADESTRSYVILSFENNGDYVDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEAKNLLSDDDSEGLTLLDLLSFTYQVARGMEFLASKNVNVLVRNTIKCVSEFSETAMAILKNPLSSGYLVGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKEWEGGLDEQRLSADSGYIIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL",
                "length": 1039,
                "header": "tr|A0A8I5ZST9-1|PGFRA_RAT Computationally mapped isoform of Platelet-derived growth factor receptor alpha  OS=Rattus norvegicus OX=10116 GN=Pdgfra PE=1 SV=1 CANONICAL=P20786-1"
            },
            "locus": {
                "chromosome": "14",
                "start_pos": 33044103,
                "end_pos": 33008956,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000118506.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000118506.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000081799.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000081799.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "G3V6A0-1",
            "url": "",
            "sequence": {
                "sequence": "MGTSQAFLVLSCLLTGPSLIVCQLLLPSILPNENEKIVPLSSSFSLRCFGESEVSWQHPMSEEEDPNVEIRTEENNSSLFVTVLEVVNASAAHTGWYTCYYNHTQTEESEIEGRHIYIYVPDPDMAFVPLGMTDSLVIVEEDDSAIIPCRTTDPDTEVTLHNNGRLVPASYDSRQGFNGTFSVGPYICEATVRGRTFKTSEFNVYALKATSELNLEMDTRQTVYKAGETIVVTCAVFNNEVVDLQWTYPGEVRNKGITMLEEIKLPSIKLVYTLTVPKATVKDSGDYECAARQATKEVKEMKTVTISVHEKGFVQIRPTFGHLETVNLHQVREFVVEVQAYPTPRISWLKDNLTLIENLTEITTDVQRSQETRYQSKLKLIRAKEEDSGHYTIIVQNDDDMKSYTFELSTLVPASILELVDDHHGSGGGQTVRCTAEGTPLPNIEWMICKDIKKCNNDTSWTVLASNVSNIITEFHQRGRSTVEGRVSFAKVEETIAVRCLAKNDLGIGNRELKLVAPTLRSELTVAAAVLVLLVIVIVSLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFMSRHPEKPKKDLDIFGLNPADESTRSYVILSFENNGDYVDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEAKNLLSDDDSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGVLLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKEWEGGLDEQRLSADSGYIIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL",
                "length": 1088,
                "header": "tr|G3V6A0-1|PGFRA_RAT Computationally mapped isoform of Platelet-derived growth factor receptor alpha  OS=Rattus norvegicus OX=10116 GN=Pdgfra PE=1 SV=1 CANONICAL=P20786-1"
            },
            "locus": {
                "chromosome": "14",
                "start_pos": 33044522,
                "end_pos": 33008956,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000003077.6",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000003077.6"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000003077.4",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000003077.4"
                    }
                ]
            }
        },
        {
            "isoform_ac": "P20786-1",
            "url": "",
            "sequence": {
                "sequence": "MGTSQAFLVLSCLLTGPSLIVCQLLLPSILPNENEKIVPLSSSFSLRCFGESEVSWQHPMSEEEDPNVEIRTEENNSSLFVTVLEVVNASAAHTGWYTCYYNHTQTEESEIEGRHIYIYVPDPDMAFVPLGMTDSLVIVEEDDSAIIPCLTTDPDTEVTLHNNGRLVPASYDSRQGFNGTFSVGPYICEATVRGRTFKTSEFNVYALKATSELNLEMDTRQTVYKAGETIVVTCAVFNNEVVDLQWTYPGEVRNKGITMLEEIKLPSIKLVYTLTVPKATVKDSGDYECAARQATKEVKEMKTVTISVHEKGFVQIRPTFGHLETVNLHQVREFVVEVQAYPTPRISWLKDNLTLIENLTEITTDVQRSQETRYQSKLKLIRAKEEDSGHYTIIVQNDDDMKSYTFELSTLVPASILELVDDHHGSGGGQTVRCTAEGTPLPNIEWMICKDIKKCNNDTSWTVLASNVSNIITEFHQRGRSTVEGRVSFAKVEETIAVRCLAKNDLGIGNRELKLVAPSLRSELTVAAAVLVLLVIVIVSLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFMSRHPEKPKKDLDIFGLNPADESTRSYVILSFENNGDYVDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEAKNLLSDDDSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGVLLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKEWEGGLDEQRLSADSGYIIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL",
                "length": 1088,
                "header": "sp|P20786-1|PGFRA_RAT Isoform 1 of Platelet-derived growth factor receptor alpha  OS=Rattus norvegicus OX=10116 GN=Pdgfra PE=1 SV=2 CANONICAL=P20786-1"
            },
            "locus": {}
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 102,
            "start_aa": "Asn",
            "end_pos": 102,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn102",
            "evidence": [
                {
                    "id": "P20786",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P20786#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 178,
            "start_aa": "Asn",
            "end_pos": 178,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn178",
            "evidence": [
                {
                    "id": "P20786",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P20786#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 352,
            "start_aa": "Asn",
            "end_pos": 352,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn352",
            "evidence": [
                {
                    "id": "P20786",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P20786#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 358,
            "start_aa": "Asn",
            "end_pos": 358,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn358",
            "evidence": [
                {
                    "id": "P20786",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P20786#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 457,
            "start_aa": "Asn",
            "end_pos": 457,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn457",
            "evidence": [
                {
                    "id": "P20786",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P20786#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 467,
            "start_aa": "Asn",
            "end_pos": 467,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn467",
            "evidence": [
                {
                    "id": "P20786",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P20786#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 75,
            "start_aa": "Asn",
            "end_pos": 75,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn75",
            "evidence": [
                {
                    "id": "P20786",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P20786#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [
        {
            "start_pos": 1017,
            "end_pos": 1017,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine; by autocatalysis",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P20786",
                    "url": "https://www.uniprot.org/uniprot/P20786"
                }
            ],
            "site_lbl": "Tyr1017"
        },
        {
            "start_pos": 571,
            "end_pos": 571,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine; by autocatalysis",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P20786",
                    "url": "https://www.uniprot.org/uniprot/P20786"
                }
            ],
            "site_lbl": "Tyr571"
        },
        {
            "start_pos": 573,
            "end_pos": 573,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine; by autocatalysis",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P20786",
                    "url": "https://www.uniprot.org/uniprot/P20786"
                }
            ],
            "site_lbl": "Tyr573"
        },
        {
            "start_pos": 719,
            "end_pos": 719,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine; by autocatalysis",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P20786",
                    "url": "https://www.uniprot.org/uniprot/P20786"
                }
            ],
            "site_lbl": "Tyr719"
        },
        {
            "start_pos": 730,
            "end_pos": 730,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine; by autocatalysis",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P20786",
                    "url": "https://www.uniprot.org/uniprot/P20786"
                }
            ],
            "site_lbl": "Tyr730"
        },
        {
            "start_pos": 741,
            "end_pos": 741,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine; by autocatalysis",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P20786",
                    "url": "https://www.uniprot.org/uniprot/P20786"
                }
            ],
            "site_lbl": "Tyr741"
        },
        {
            "start_pos": 753,
            "end_pos": 753,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine; by autocatalysis",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P20786",
                    "url": "https://www.uniprot.org/uniprot/P20786"
                }
            ],
            "site_lbl": "Tyr753"
        },
        {
            "start_pos": 761,
            "end_pos": 761,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine; by autocatalysis",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P20786",
                    "url": "https://www.uniprot.org/uniprot/P20786"
                }
            ],
            "site_lbl": "Tyr761"
        },
        {
            "start_pos": 767,
            "end_pos": 767,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine; by autocatalysis",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P20786",
                    "url": "https://www.uniprot.org/uniprot/P20786"
                }
            ],
            "site_lbl": "Tyr767"
        },
        {
            "start_pos": 848,
            "end_pos": 848,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine; by autocatalysis",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P20786",
                    "url": "https://www.uniprot.org/uniprot/P20786"
                }
            ],
            "site_lbl": "Tyr848"
        },
        {
            "start_pos": 987,
            "end_pos": 987,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine; by autocatalysis",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P20786",
                    "url": "https://www.uniprot.org/uniprot/P20786"
                }
            ],
            "site_lbl": "Tyr987"
        }
    ],
    "glycation": [],
    "keywords": [
        "enzyme",
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [
        {
            "title": "Isolation and characterization of the alpha platelet-derived growth factor receptor from rat olfactory epithelium.",
            "journal": "Mol. Cell. Biol.",
            "date": "1990",
            "authors": "Lee KH, Bowen-Pope DF, Reed RR",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P20786",
                    "url": "https://www.uniprot.org/uniprot/P20786"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "2157969",
                    "url": "https://glygen.org/publication/PubMed/2157969"
                }
            ]
        },
        {
            "title": "Inhibition of platelet-derived growth factor (PDGF) receptor affects follicular development and ovarian proliferation, apoptosis and angiogenesis in prepubertal eCG-treated rats.",
            "journal": "Molecular and cellular endocrinology",
            "date": "2015",
            "authors": "Pascuali N, Scotti L, Abramovich D, Irusta G, Di Pietro M, Bas D, Tesone M, Parborell F",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_036934",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036934"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "25937181",
                    "url": "https://glygen.org/publication/PubMed/25937181"
                }
            ]
        },
        {
            "title": "The platelet-derived growth factor receptor/STAT3 signaling pathway regulates the phenotypic transition of corpus cavernosum smooth muscle in rats.",
            "journal": "PloS one",
            "date": "2017",
            "authors": "Yan JF, Huang WJ, Zhao JF, Fu HY, Zhang GY, Huang XJ, Lv BD",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_036934",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036934"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "28245285",
                    "url": "https://glygen.org/publication/PubMed/28245285"
                }
            ]
        },
        {
            "title": "PDGF-mediated PI3K/AKT/beta-catenin signaling regulates gap junctions in corpus cavernosum smooth muscle cells.",
            "journal": "Experimental cell research",
            "date": "2018",
            "authors": "Zhang X, Zhao F, Zhao JF, Fu HY, Huang XJ, Lv BD",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_036934",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036934"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "29174980",
                    "url": "https://glygen.org/publication/PubMed/29174980"
                }
            ]
        },
        {
            "title": "COP9 signalosome subunit 6 mediates PDGF -induced pulmonary arterial smooth muscle cells proliferation.",
            "journal": "Experimental cell research",
            "date": "2018",
            "authors": "Zhu Y, Li F, Shi W, Zhai C, Wang J, Yan X, Wang Q, Zhang Q, Yang L, Gao L, Li M",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_036934",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036934"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "30180991",
                    "url": "https://glygen.org/publication/PubMed/30180991"
                }
            ]
        },
        {
            "title": "Conservation in sequence and affinity of human and rodent PDGF ligands and receptors.",
            "journal": "Biochim. Biophys. Acta",
            "date": "1993",
            "authors": "Herren B., Pech M., Loetscher P., Rouge M., Weyer K.A.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P20786",
                    "url": "https://www.uniprot.org/uniprot/P20786"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "8318539",
                    "url": "https://glygen.org/publication/PubMed/8318539"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:25267",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:25267",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-1257604",
            "name": "PIP3 activates AKT signaling",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-1257604",
            "resource": "Reactome",
            "description": "PIP3 activates AKT signaling"
        },
        {
            "id": "R-RNO-186763",
            "name": "Downstream signal transduction",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-186763",
            "resource": "Reactome",
            "description": "Downstream signal transduction"
        },
        {
            "id": "R-RNO-186797",
            "name": "Signaling by PDGF",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-186797",
            "resource": "Reactome",
            "description": "Signaling by PDGF"
        },
        {
            "id": "R-RNO-5673001",
            "name": "RAF/MAP kinase cascade",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5673001",
            "resource": "Reactome",
            "description": "RAF/MAP kinase cascade"
        },
        {
            "id": "R-RNO-6811558",
            "name": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6811558",
            "resource": "Reactome",
            "description": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "P16234-1",
            "protein_name": "Platelet-derived growth factor receptor alpha",
            "gene_name": "PDGFRA",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MGTSHPAFLVLGCLLTGLSLILCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYPMSEEESSDVEIRNEENNSGLFVTVLEVSSASAAHTGLYTCYYNHTQTEENELEGRHIYIYVPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLHNSEGVVPASYDSRQGFNGTFTVGPYICEATVKGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNNEVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATREVKEMKKVTISVHEKGFIEIKPTFSQLEAVNLHEVKHFVVEVRAYPPPRISWLKNNLTLIENLTEITTDVEKIQEIRYRSKLKLIRAKEEDSGHYTIVAQNEDAVKSYTFELLTQVPSSILDLVDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTILANNVSNIITEIHSRDRSTVEGRVTFAKVEETIAVRCLAKNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIVIISLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSHHPEKPKKELDIFGLNPADESTRSYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKNLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYIIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL",
                "length": 1089
            },
            "evidence": [
                {
                    "id": "45224974",
                    "url": "http://www.informatics.jax.org/homology/45224974",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "P26618-1",
            "protein_name": "Platelet-derived growth factor receptor alpha",
            "gene_name": "Pdgfra",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MGTSHQVFLVLSCLLTGPGLISCQLLLPSILPNENEKIVQLNSSFSLRCVGESEVSWQHPMSEEDDPNVEIRSEENNSGLFVTVLEVVNASAAHTGWYTCYYNHTQTDESEIEGRHIYIYVPDPDMAFVPLGMTDSLVIVEEDDSAIIPCRTTDPETQVTLHNNGRLVPASYDSRQGFNGTFSVGPYICEATVKGRTFKTSEFNVYALKATSELNLEMDARQTVYKAGETIVVTCAVFNNEVVDLQWTYPGEVRNKGITMLEEIKLPSIKLVYTLTVPKATVKDSGEYECAARQATKEVKEMKRVTISVHEKGFVEIEPTFGQLEAVNLHEVREFVVEVQAYPTPRISWLKDNLTLIENLTEITTDVQKSQETRYQSKLKLIRAKEEDSGHYTIIVQNEDDVKSYTFELSTLVPASILDLVDDHHGSGGGQTVRCTAEGTPLPEIDWMICKHIKKCNNDTSWTVLASNVSNIITELPRRGRSTVEGRVSFAKVEETIAVRCLAKNNLSVVARELKLVAPTLRSELTVAAAVLVLLVIVIVSLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFMSQHPEKPKKDLDIFGLNPADESTRSYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKNLLSDDDSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYIIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL",
                "length": 1089
            },
            "evidence": [
                {
                    "id": "45224974",
                    "url": "http://www.informatics.jax.org/homology/45224974",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 65,
                "go_terms": [
                    {
                        "name": "estrogen metabolic process",
                        "id": "GO:0008210",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008210",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "in utero embryonic development",
                        "id": "GO:0001701",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001701",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of cytosolic calcium ion concentration",
                        "id": "GO:0007204",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007204",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of phospholipase C activity",
                        "id": "GO:0010863",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010863",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "peptidyl-tyrosine phosphorylation",
                        "id": "GO:0018108",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018108",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "extracellular matrix organization",
                        "id": "GO:0030198",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of cell migration",
                        "id": "GO:0030335",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "white fat cell differentiation",
                        "id": "GO:0050872",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050872",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of ERK1 and ERK2 cascade",
                        "id": "GO:0070374",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "lung development",
                        "id": "GO:0030324",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030324",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein autophosphorylation",
                        "id": "GO:0046777",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046777",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cardiac myofibril assembly",
                        "id": "GO:0055003",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055003",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell chemotaxis",
                        "id": "GO:0060326",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060326",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "retina vasculature development in camera-type eye",
                        "id": "GO:0061298",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061298",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "platelet aggregation",
                        "id": "GO:0070527",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070527",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "odontogenesis of dentin-containing tooth",
                        "id": "GO:0042475",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042475",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "phosphatidylinositol-mediated signaling",
                        "id": "GO:0048015",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048015",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of fibroblast proliferation",
                        "id": "GO:0048146",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048146",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "embryonic cranial skeleton morphogenesis",
                        "id": "GO:0048701",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048701",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "roof of mouth development",
                        "id": "GO:0060021",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060021",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "face morphogenesis",
                        "id": "GO:0060325",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060325",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of chemotaxis",
                        "id": "GO:0050920",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050920",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "Leydig cell differentiation",
                        "id": "GO:0033327",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033327",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "adrenal gland development",
                        "id": "GO:0030325",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030325",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "hematopoietic progenitor cell differentiation",
                        "id": "GO:0002244",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002244",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to reactive oxygen species",
                        "id": "GO:0034614",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034614",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of phosphatidylinositol 3-kinase activity",
                        "id": "GO:0043552",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043552",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to amino acid stimulus",
                        "id": "GO:0071230",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071230",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of platelet activation",
                        "id": "GO:0010544",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010544",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "male genitalia development",
                        "id": "GO:0030539",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030539",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "luteinization",
                        "id": "GO:0001553",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001553",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway",
                        "id": "GO:0038091",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038091",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "metanephric glomerular capillary formation",
                        "id": "GO:0072277",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072277",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of mesenchymal stem cell differentiation",
                        "id": "GO:2000739",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000739",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "signal transduction involved in regulation of gene expression",
                        "id": "GO:0023019",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023019",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "embryonic digestive tract morphogenesis",
                        "id": "GO:0048557",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048557",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein phosphorylation",
                        "id": "GO:0006468",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "transmembrane receptor protein tyrosine kinase signaling pathway",
                        "id": "GO:0007169",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to growth factor stimulus",
                        "id": "GO:0071363",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071363",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of cell population proliferation",
                        "id": "GO:0008284",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell migration",
                        "id": "GO:0016477",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "male gonad development",
                        "id": "GO:0008584",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008584",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to organic substance",
                        "id": "GO:0010033",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010033",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of kinase activity",
                        "id": "GO:0033674",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033674",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "animal organ morphogenesis",
                        "id": "GO:0009887",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to estradiol",
                        "id": "GO:0032355",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032355",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to cytokine",
                        "id": "GO:0034097",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034097",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of peptidyl-tyrosine phosphorylation",
                        "id": "GO:0050731",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050731",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to hormone",
                        "id": "GO:0009725",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009725",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to estrogen",
                        "id": "GO:0043627",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043627",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "skeletal system morphogenesis",
                        "id": "GO:0048705",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048705",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "female gonad development",
                        "id": "GO:0008585",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008585",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to inorganic substance",
                        "id": "GO:0010035",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010035",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "embryonic skeletal system morphogenesis",
                        "id": "GO:0048704",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048704",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "inner ear development",
                        "id": "GO:0048839",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048839",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "wound healing",
                        "id": "GO:0042060",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042060",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to interleukin-1",
                        "id": "GO:0071347",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071347",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "platelet-derived growth factor receptor signaling pathway",
                        "id": "GO:0048008",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048008",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to hyperoxia",
                        "id": "GO:0055093",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055093",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to fibroblast growth factor stimulus",
                        "id": "GO:0044344",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044344",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "platelet-derived growth factor receptor-alpha signaling pathway",
                        "id": "GO:0035790",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035790",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "lung growth",
                        "id": "GO:0060437",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060437",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "anatomical structure morphogenesis",
                        "id": "GO:0009653",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of branching involved in lung morphogenesis",
                        "id": "GO:0061047",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061047",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to formaldehyde",
                        "id": "GO:1904404",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904404",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 11,
                "go_terms": [
                    {
                        "name": "platelet-derived growth factor receptor binding",
                        "id": "GO:0005161",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005161",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ATP binding",
                        "id": "GO:0005524",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein homodimerization activity",
                        "id": "GO:0042803",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "vascular endothelial growth factor receptor activity",
                        "id": "GO:0005021",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005021",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "platelet-derived growth factor alpha-receptor activity",
                        "id": "GO:0005018",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005018",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "vascular endothelial growth factor binding",
                        "id": "GO:0038085",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038085",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "platelet-derived growth factor binding",
                        "id": "GO:0048407",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048407",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "BBSome binding",
                        "id": "GO:0062063",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062063",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "transmembrane receptor protein tyrosine kinase activity",
                        "id": "GO:0004714",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004714",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein kinase activity",
                        "id": "GO:0004672",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "phosphatidylinositol 3-kinase binding",
                        "id": "GO:0043548",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043548",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 13,
                "go_terms": [
                    {
                        "name": "nucleoplasm",
                        "id": "GO:0005654",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "Golgi apparatus",
                        "id": "GO:0005794",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cilium",
                        "id": "GO:0005929",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell junction",
                        "id": "GO:0030054",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "external side of plasma membrane",
                        "id": "GO:0009897",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "microvillus",
                        "id": "GO:0005902",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein-containing complex",
                        "id": "GO:0032991",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell surface",
                        "id": "GO:0009986",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "axon",
                        "id": "GO:0030424",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "receptor complex",
                        "id": "GO:0043235",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "P20786",
                                "url": "https://www.uniprot.org/uniprot/P20786"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 102,
            "end_pos": 104,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 178,
            "end_pos": 180,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 352,
            "end_pos": 354,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 358,
            "end_pos": 360,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 457,
            "end_pos": 459,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 467,
            "end_pos": 469,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 75,
            "end_pos": 77,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 76,
            "end_pos": 78,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 88,
            "end_pos": 90,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [
        {
            "annotation": "Ubiquitinated, leading to its internalization and degradation.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P20786",
                    "url": "https://www.uniprot.org/uniprot/P20786"
                },
                {
                    "database": "PubMed",
                    "id": "P26618",
                    "url": "https://glygen.org/publication/PubMed/P26618"
                }
            ]
        }
    ],
    "interactions": [],
    "reactions": [
        {
            "id": "10596",
            "name": "",
            "equation": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein]",
            "summary": "",
            "cellular_location": "",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q63132-1",
                "Q9WUD9-1",
                "P57760-1",
                "P35739-1",
                "F1LYY7-1",
                "A0A8I6GCV6-1",
                "Q63117-1",
                "Q5U2X5-1",
                "Q63474-1",
                "O08680-1",
                "O35346-1",
                "P54757-1",
                "P54758-1",
                "P54759-1",
                "P70600-1",
                "Q00495-1",
                "Q03351-1",
                "Q04589-1",
                "P06494-1",
                "P09759-1",
                "P29321-1",
                "P32577-1",
                "Q6XUX2-1",
                "Q4V8A3-1",
                "Q62662-1",
                "Q62799-1",
                "Q62844-1",
                "Q62956-1",
                "Q63184-1",
                "Q63470-1",
                "Q498D6-1",
                "Q01621-1",
                "Q6P6U0-1",
                "Q63604-1",
                "P09760-1",
                "Q01986-1",
                "Q62862-1",
                "Q63572-1",
                "Q07014-1",
                "Q4KSH7-1",
                "G3V9H8-1",
                "P15127-1",
                "O08775-1",
                "P53767-1",
                "Q05030-1",
                "P55146-1",
                "Q64725-1",
                "Q63802-1",
                "Q64716-1",
                "P09215-1",
                "Q62689-1",
                "F1LM93-1",
                "P36506-1",
                "P20786-1",
                "P24062-1",
                "Q924U5-1",
                "Q63272-1",
                "B2RYC7-1",
                "P41243-1",
                "M0RDA4-1",
                "Q62838-1",
                "Q63116-1",
                "A0A8I6AM23-1",
                "P50545-1",
                "P57097-1",
                "P97523-1",
                "Q91ZT1-1",
                "D4A7W7-1",
                "F1LVI0-1",
                "E9PSY0-1",
                "A0A0G2K6M9-1",
                "F1LSN4-1",
                "F1MAJ0-1",
                "A0A0R4J8U1-1",
                "A0A8I6A5T6-1",
                "D3ZDS3-1",
                "D4ADZ5-1",
                "F1LSG7-1",
                "F1LRZ0-1",
                "D3ZBN3-1",
                "F1M0N1-1",
                "G3V6K6-1",
                "D3ZD03-1",
                "D3ZZK3-1",
                "E9PT20-1",
                "D4A584-1",
                "D3ZDH4-1",
                "A0A8I5ZVE3-1",
                "A0A8I6AWX7-1",
                "Q4KM97-1",
                "Q501W1-1",
                "B5DFD6-1",
                "Q5FVG7-1",
                "D3ZCD0-1",
                "A0A8I5ZP97-1",
                "A0A0G2JW59-1",
                "B1WC09-1",
                "Q01134-1",
                "P11980-1",
                "G3V783-1",
                "Q9UM73-1",
                "O15146-1",
                "P42679-1",
                "P08922-1",
                "P07947-1",
                "Q12866-1",
                "P00519-1",
                "Q07912-1",
                "P42684-1",
                "Q9UF33-1",
                "P10721-1",
                "P08069-1",
                "P06239-1",
                "P51451-1",
                "Q06187-1",
                "P51813-1",
                "Q9UIG0-1",
                "P49760-1",
                "P49761-4",
                "Q9HAZ1-1",
                "P49759-1",
                "P07333-1",
                "Q5JZY3-1",
                "Q6XUX3-1",
                "P00533-1",
                "Q9Y463-1",
                "P29317-1",
                "Q9NR20-1",
                "Q13627-1",
                "P54760-1",
                "P41240-1",
                "Q16832-1",
                "Q15375-1",
                "P29323-1",
                "P22455-1",
                "P16591-1",
                "P29322-1",
                "P54756-1",
                "P29320-1",
                "Q08345-1",
                "Q92630-1",
                "Q05397-1",
                "P54753-1",
                "Q15303-1",
                "P36888-1",
                "P04626-1",
                "P21860-1",
                "Q14289-1",
                "O43781-1",
                "P54764-1",
                "P19525-1",
                "P21709-1",
                "P54762-1",
                "P22607-1",
                "P21802-1",
                "P52333-1",
                "P11362-1",
                "P42685-1",
                "P06213-1",
                "P14616-1",
                "Q05655-1",
                "Q08881-1",
                "P07332-1",
                "P08631-1",
                "P29376-1",
                "O60674-1",
                "P23458-1",
                "P09769-1",
                "P43405-1",
                "P06241-1",
                "P07948-1",
                "P46734-1",
                "P45985-1",
                "Q02750-1",
                "P52564-1",
                "O14733-1",
                "Q13163-1",
                "Q16288-1",
                "P36507-1",
                "Q16620-1",
                "P08581-1",
                "P04629-1",
                "Q14680-1",
                "Q01974-1",
                "P09619-1",
                "P07949-1",
                "Q504Y2-1",
                "P34925-1",
                "P16234-1",
                "Q13882-1",
                "Q04912-1",
                "O43353-1",
                "Q06418-1",
                "P30530-1",
                "Q96KB5-1",
                "Q15569-1",
                "Q96S53-1",
                "Q6J9G0-1",
                "P42680-1",
                "P35916-2",
                "P0C1S8-1",
                "P17948-1",
                "P29597-1",
                "P42681-1",
                "P35590-1",
                "Q13470-1",
                "P33981-1",
                "P30291-1",
                "P12931-1",
                "P35968-1",
                "P43403-1",
                "O75716-1",
                "Q02763-1",
                "Q9H3Y6-1",
                "P35790-1",
                "P14618-1",
                "P24604-1",
                "O54967-1",
                "P00520-1",
                "Q9Z188-1",
                "P35969-1",
                "P52332-1",
                "P08923-1",
                "Q00342-1",
                "Q62120-1",
                "Q4JIM5-1",
                "P97504-1",
                "P42682-1",
                "Q60629-1",
                "P97793-1",
                "P16277-1",
                "O35491-1",
                "O35492-1",
                "O35493-1",
                "Q9Z277-1",
                "P35991-1",
                "P22518-1",
                "Q8BYG9-1",
                "P54754-1",
                "P54761-1",
                "Q6XUX1-1",
                "Q62371-1",
                "Q60750-1",
                "Q61527-1",
                "Q62413-1",
                "Q61214-1",
                "Q61772-1",
                "Q61851-1",
                "Q922Y0-1",
                "Q922K9-1",
                "O09127-1",
                "P16092-1",
                "Q03142-1",
                "P29319-1",
                "Q01279-1",
                "P70424-1",
                "P21803-1",
                "Q8CBF3-1",
                "P41241-1",
                "Q03963-1",
                "Q8BI55-1",
                "P54763-3",
                "P16879-1",
                "P09581-1",
                "P34152-3",
                "P14234-1",
                "P39688-1",
                "Q03146-1",
                "Q03145-1",
                "Q61526-1",
                "P70451-1",
                "Q5U4C9-1",
                "Q9QVP9-1",
                "Q03137-1",
                "Q60751-1",
                "Q62137-1",
                "P28867-1",
                "P25911-1",
                "P48025-1",
                "Q9WTL4-1",
                "P41242-1",
                "P05532-1",
                "P06240-1",
                "P08103-1",
                "P15208-1",
                "Q03526-1",
                "Q9WVS7-1",
                "P70236-1",
                "P31938-1",
                "P47809-1",
                "Q61846-1",
                "Q60805-1",
                "Q63932-1",
                "O09110-1",
                "P26618-1",
                "Q8CE90-1",
                "P16056-1",
                "P05622-1",
                "P15209-1",
                "Q6VNS1-1",
                "Q61006-1",
                "Q3UFB7-1",
                "Q5RJI4-1",
                "Q9JJ78-1",
                "P58801-1",
                "P55144-1",
                "Q8VCT9-1",
                "O70146-1",
                "Q62190-1",
                "Q62270-1",
                "P35546-1",
                "P35761-1",
                "Q9Z138-1",
                "Q9R117-1",
                "O88697-1",
                "P05480-2",
                "Q01887-1",
                "Q02858-1",
                "Q06806-1",
                "Q00993-1",
                "Q64434-1",
                "Q78DX7-1",
                "Q6J9G1-1",
                "Q99ML2-1",
                "P43404-1",
                "P35917-1",
                "P47810-1",
                "P35918-1",
                "Q04736-1",
                "Q66JT0-1",
                "O54804-1",
                "P52480-1",
                "P14680-1",
                "P21965-1",
                "P22216-1",
                "P32490-1",
                "P06784-1",
                "P08018-1",
                "P32350-1",
                "P32491-1",
                "P54199-1",
                "Q54G28-1",
                "Q54N73-1",
                "Q54R58-1",
                "P18160-1",
                "P18161-1",
                "Q54BC9-1",
                "Q54I36-1",
                "Q54QV3-1",
                "Q552C6-1",
                "Q55CL6-1",
                "Q75JK0-1",
                "Q76NV1-1",
                "Q23977-1",
                "P18475-1",
                "P09208-1",
                "P13368-1",
                "Q24145-1",
                "Q24488-1",
                "Q27324-1",
                "P08630-1",
                "P00522-1",
                "P00528-1",
                "P04412-1",
                "Q9V422-1",
                "Q9V6K3-1",
                "Q9V9J3-1",
                "Q9VBW3-1",
                "P49762-1",
                "P83102-1",
                "Q24324-1",
                "Q9VPC0-1",
                "P49657-1",
                "P54350-1",
                "P18106-4",
                "Q07407-1",
                "Q09147-1",
                "Q24592-1",
                "Q9I7F7-1",
                "Q9V3D5-1",
                "Q9VZI2-1",
                "Q9V4E5-1",
                "Q8INJ8-1",
                "Q7KJ08-1",
                "Q9VJ04-1"
            ],
            "evidence": [
                {
                    "id": "10596",
                    "database": "Rhea",
                    "url": "https://www.rhea-db.org/rhea/10596"
                }
            ]
        },
        {
            "id": "R-RNO-1524182",
            "name": "Activated PLC gamma dissociates from the PDGF receptor",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P10686-1",
                "P20786-1",
                "Q05030-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-1524182",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-1524182"
                }
            ]
        },
        {
            "id": "R-RNO-1524186",
            "name": "Phosphorylation of PLCgamma by PDGFR",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P10686-1",
                "P20786-1",
                "Q05030-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-1524186",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-1524186"
                }
            ]
        },
        {
            "id": "R-RNO-186765",
            "name": "PLC-gamma binds to the active receptor",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P10686-1",
                "P20786-1",
                "Q05030-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-186765",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-186765"
                }
            ]
        },
        {
            "id": "R-RNO-186773",
            "name": "PDGF dimer binds two receptors simultaneously",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P20786-1",
                "Q05030-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-186773",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-186773"
                }
            ]
        },
        {
            "id": "R-RNO-186778",
            "name": "SHP2 binds to the active receptor",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P41499-2",
                "P20786-1",
                "Q05030-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-186778",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-186778"
                }
            ]
        },
        {
            "id": "R-RNO-186780",
            "name": "PI3-kinase binds to the active receptor",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P20786-1",
                "Q05030-1",
                "A0A0G2K344-1",
                "Q9Z1L0-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-186780",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-186780"
                }
            ]
        },
        {
            "id": "R-RNO-186800",
            "name": "PI3K catalyses the phosphorylation of PIP2 to PIP3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P20786-1",
                "Q05030-1",
                "A0A0G2K344-1",
                "Q9Z1L0-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-186800",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-186800"
                }
            ]
        },
        {
            "id": "R-RNO-186819",
            "name": "SH2 domain of Src binds to the active receptor",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q9WUD9-1",
                "P20786-1",
                "Q05030-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-186819",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-186819"
                }
            ]
        },
        {
            "id": "R-RNO-186826",
            "name": "GRB2:SOS1 complex binds to the active receptor",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P20786-1",
                "Q05030-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-186826",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-186826"
                }
            ]
        },
        {
            "id": "R-RNO-186834",
            "name": "SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS)",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P08644-1",
                "P20171-1",
                "P20786-1",
                "Q05030-1",
                "Q04970-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-186834",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-186834"
                }
            ]
        },
        {
            "id": "R-RNO-2316434",
            "name": "PI3K phosphorylates PIP2 to PIP3",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q9WUD9-1",
                "P06494-1",
                "Q62844-1",
                "P41499-2",
                "A0A0G2JW59-1",
                "A0A8I6G1H3-1",
                "Q63116-1",
                "Q04589-1",
                "Q62611-1",
                "Q9Z2Y9-1",
                "F1LSG7-1",
                "A0A8I5Y949-1",
                "F1LSN4-1",
                "Q62799-1",
                "B5DF45-1",
                "P20786-1",
                "Q05030-1",
                "Q6RUV5-1",
                "A0A0G2K344-1",
                "Q01621-1",
                "Q498D6-1",
                "Q63621-1",
                "Q9Z1L0-1",
                "P97523-1",
                "G3V6K6-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-2316434",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-2316434"
                }
            ]
        },
        {
            "id": "R-RNO-380780",
            "name": "Activation of Src",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "Q9WUD9-1",
                "P20786-1",
                "Q05030-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-380780",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-380780"
                }
            ]
        },
        {
            "id": "R-RNO-380782",
            "name": "STAT binds to the active receptor",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P20786-1",
                "Q05030-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-380782",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-380782"
                }
            ]
        },
        {
            "id": "R-RNO-382052",
            "name": "p130Cas and C3G bind PDGFR bound Crk",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P20786-1",
                "Q05030-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-382052",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-382052"
                }
            ]
        },
        {
            "id": "R-RNO-382055",
            "name": "Grb7 binds to the active PDGF receptor",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P20786-1",
                "Q05030-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-382055",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-382055"
                }
            ]
        },
        {
            "id": "R-RNO-382056",
            "name": "Crk binds to the active PDGF receptor",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P20786-1",
                "Q05030-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-382056",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-382056"
                }
            ]
        },
        {
            "id": "R-RNO-382058",
            "name": "Nck binds to the active PDGF receptor",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P20786-1",
                "Q05030-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-382058",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-382058"
                }
            ]
        },
        {
            "id": "R-RNO-389083",
            "name": "Autophosphorylation of PDGF alpha receptors",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P20786-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-389083",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-389083"
                }
            ]
        },
        {
            "id": "R-RNO-389086",
            "name": "Autophosphorylation of PDGF alpha/beta receptors",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P20786-1",
                "Q05030-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-389086",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-389086"
                }
            ]
        },
        {
            "id": "R-RNO-5672965",
            "name": "RAS GEFs promote RAS nucleotide exchange",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P06494-1",
                "P08413-1",
                "Q62844-1",
                "P11275-1",
                "P11730-1",
                "P08644-1",
                "P20171-1",
                "A0A0G2JW59-1",
                "Q63116-1",
                "Q03348-1",
                "Q04589-1",
                "P15791-1",
                "Q9Z2Y9-1",
                "F1LSG7-1",
                "D3ZCD0-1",
                "F1LSN4-1",
                "O35346-1",
                "Q62799-1",
                "G3V9H8-1",
                "P20786-1",
                "Q05030-1",
                "Q62689-1",
                "Q04970-1",
                "Q498D6-1",
                "P97523-1",
                "G3V6K6-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-5672965",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5672965"
                }
            ]
        },
        {
            "id": "R-RNO-8864036",
            "name": "PTPN12 dephosphorylates PDGFRB at Y1021",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "G3V7Q4-1",
                "P20786-1",
                "Q05030-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-8864036",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-8864036"
                }
            ]
        },
        {
            "id": "R-RNO-9674093",
            "name": "PDGFRs bind type I TKI",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P20786-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-9674093",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-9674093"
                }
            ]
        },
        {
            "id": "R-RNO-9674095",
            "name": "PDGFRs bind type II TKI",
            "equation": "",
            "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>",
            "cellular_location": "cytosol, plasma membrane",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P20786-1",
                "Q05030-1"
            ],
            "evidence": [
                {
                    "id": "R-RNO-9674095",
                    "database": "Reactome",
                    "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-9674095"
                }
            ]
        }
    ],
    "reaction_participants": [],
    "reaction_enzymes": [
        {
            "uniprot_ac": "A0A0G2JW59",
            "gene_name": "Flt3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A0G2JW59",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2JW59"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A0G2JW59",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2JW59"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A0G2K344",
            "gene_name": "Pik3ca",
            "activity": [
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A0G2K344",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2K344"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.153",
                    "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).",
                    "evidence": [
                        {
                            "id": "A0A0G2K344",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2K344"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.137",
                    "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).",
                    "evidence": [
                        {
                            "id": "A0A0G2K344",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2K344"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.137",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A0G2K344",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2K344"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.153",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A0G2K344",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2K344"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A0G2K6M9",
            "gene_name": "Btk",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A0G2K6M9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2K6M9"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A0G2K6M9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0G2K6M9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A0R4J8U1",
            "gene_name": "Zap70",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A0R4J8U1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0R4J8U1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A0R4J8U1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0R4J8U1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I5Y949",
            "gene_name": "Pik3cd",
            "activity": [
                {
                    "ec_number": "2.7.1.153",
                    "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).",
                    "evidence": [
                        {
                            "id": "A0A8I5Y949",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I5Y949"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.153",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I5Y949",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I5Y949"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I5ZP97",
            "gene_name": "Dyrk1b",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I5ZP97",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I5ZP97"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I5ZP97",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I5ZP97"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I5ZVE3",
            "gene_name": "Ephb3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I5ZVE3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I5ZVE3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I5ZVE3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I5ZVE3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I6A5T6",
            "gene_name": "Mst1r",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I6A5T6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6A5T6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I6A5T6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6A5T6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I6AM23",
            "gene_name": "Jak1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I6AM23",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6AM23"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I6AM23",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6AM23"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I6AWX7",
            "gene_name": "Dyrk4",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I6AWX7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6AWX7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I6AWX7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6AWX7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I6G1H3",
            "gene_name": "Irak4",
            "activity": [
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I6G1H3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6G1H3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I6G1H3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6G1H3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "A0A8I6GCV6",
            "gene_name": "Ltk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I6GCV6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6GCV6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "A0A8I6GCV6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6GCV6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "B1WC09",
            "gene_name": "Ddr2",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "B1WC09",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B1WC09"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "B1WC09",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B1WC09"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "B2RYC7",
            "gene_name": "Tec",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "B2RYC7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B2RYC7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "B2RYC7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B2RYC7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "B5DF45",
            "gene_name": "Traf6",
            "activity": [
                {
                    "ec_number": "2.3.2.27",
                    "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.",
                    "evidence": [
                        {
                            "id": "B5DF45",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B5DF45"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.2.27",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "B5DF45",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B5DF45"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "B5DFD6",
            "gene_name": "Tie1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "B5DFD6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B5DFD6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "B5DFD6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/B5DFD6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZBN3",
            "gene_name": "Epha2",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZBN3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZBN3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D3ZBN3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZBN3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZCD0",
            "gene_name": "Tek",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZCD0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZCD0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D3ZCD0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZCD0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZD03",
            "gene_name": "Tyk2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZD03",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZD03"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D3ZD03",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZD03"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZDH4",
            "gene_name": "Epha1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZDH4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZDH4"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D3ZDH4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZDH4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZDS3",
            "gene_name": "Ptk6",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZDS3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZDS3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D3ZDS3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZDS3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D3ZZK3",
            "gene_name": "Epha4",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D3ZZK3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZZK3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D3ZZK3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D3ZZK3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D4A584",
            "gene_name": "Fes",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D4A584",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4A584"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D4A584",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4A584"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D4A7W7",
            "gene_name": "Itk",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D4A7W7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4A7W7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D4A7W7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4A7W7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "D4ADZ5",
            "gene_name": "Wee2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "D4ADZ5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4ADZ5"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "D4ADZ5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/D4ADZ5"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "E9PSY0",
            "gene_name": "Axl",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "E9PSY0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/E9PSY0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "E9PSY0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/E9PSY0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "E9PT20",
            "gene_name": "Abl1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "E9PT20",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/E9PT20"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "E9PT20",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/E9PT20"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LM93",
            "gene_name": "Yes1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LM93",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LM93"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LM93",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LM93"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LRZ0",
            "gene_name": "Alk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LRZ0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LRZ0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LRZ0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LRZ0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LSG7",
            "gene_name": "Fgfr2",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LSG7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LSG7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LSG7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LSG7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LSN4",
            "gene_name": "Fgfr3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LSN4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LSN4"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LSN4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LSN4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LVI0",
            "gene_name": "Bmx",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LVI0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LVI0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LVI0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LVI0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1LYY7",
            "gene_name": "Dyrk2",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "F1LYY7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LYY7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1LYY7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1LYY7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1M0N1",
            "gene_name": "Abl2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1M0N1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1M0N1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1M0N1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1M0N1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "F1MAJ0",
            "gene_name": "Ephb2",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "F1MAJ0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1MAJ0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "F1MAJ0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F1MAJ0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "G3V6K6",
            "gene_name": "Egfr",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "G3V6K6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V6K6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "G3V6K6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V6K6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "G3V783",
            "gene_name": "Ripk2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "G3V783",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V783"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "G3V783",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V783"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "G3V783",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V783"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "G3V783",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V783"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "G3V7Q4",
            "gene_name": "Ptpn12",
            "activity": [
                {
                    "ec_number": "3.1.3.48",
                    "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.",
                    "evidence": [
                        {
                            "id": "G3V7Q4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V7Q4"
                        }
                    ]
                },
                {
                    "ec_number": "3.1.3.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "G3V7Q4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V7Q4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "G3V9H8",
            "gene_name": "Ret",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "G3V9H8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V9H8"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "G3V9H8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/G3V9H8"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "M0RDA4",
            "gene_name": "Ephb4",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "M0RDA4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/M0RDA4"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "M0RDA4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/M0RDA4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O08680",
            "gene_name": "Epha3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O08680",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O08680"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O08680",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O08680"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O08775",
            "gene_name": "Kdr",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O08775",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O08775"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O08775",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O08775"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O09110",
            "gene_name": "Map2k3",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O09110",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O09110"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O09110",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O09110"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O09127",
            "gene_name": "Epha8",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O09127",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O09127"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O09127",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O09127"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O14733",
            "gene_name": "MAP2K7",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O14733",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O14733"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O14733",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O14733"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O15146",
            "gene_name": "MUSK",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O15146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O15146"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O15146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O15146"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O35346",
            "gene_name": "Ptk2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O35346",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35346"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O35346",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35346"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O35491",
            "gene_name": "Clk2",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O35491",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35491"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O35491",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35491"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O35492",
            "gene_name": "Clk3",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O35492",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35492"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O35492",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35492"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O35493",
            "gene_name": "Clk4",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O35493",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35493"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O35493",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O35493"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O43353",
            "gene_name": "RIPK2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "O43353",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O43353"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O43353",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O43353"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O43353",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O43353"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O43781",
            "gene_name": "DYRK3",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "O43781",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O43781"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O43781",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O43781"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O54804",
            "gene_name": "Chka",
            "activity": [
                {
                    "ec_number": "2.7.1.32",
                    "activity": "ATP + choline = ADP + H(+) + phosphocholine.",
                    "evidence": [
                        {
                            "id": "O54804",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54804"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.82",
                    "activity": "ATP + ethanolamine = ADP + H(+) + phosphoethanolamine.",
                    "evidence": [
                        {
                            "id": "O54804",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54804"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.32",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "O54804",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O54804"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "O54967",
            "gene_name": "Tnk2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.2",
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                            "id": "P06239",
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                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.2",
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                            "id": "P07333",
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                    "ec_number": "2.7.10.1",
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                            "id": "P07947",
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                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P07948",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P07948",
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P07949",
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                            "url": "https://www.uniprot.org/uniprot/P07949"
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "P07949",
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                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P08018",
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                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P08018",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08018"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P08069",
            "gene_name": "IGF1R",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P08069",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08069"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P08069",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08069"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P08103",
            "gene_name": "Hck",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P08103",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08103"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P08103",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08103"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P08413",
            "gene_name": "Camk2b",
            "activity": [
                {
                    "ec_number": "2.7.11.17",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P08413",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08413"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.17",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P08413",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08413"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P08581",
            "gene_name": "MET",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P08581",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08581"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P08581",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08581"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P08630",
            "gene_name": "Btk",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P08630",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08630"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P08630",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08630"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P08631",
            "gene_name": "HCK",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P08631",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08631"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P08631",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08631"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P08644",
            "gene_name": "Kras",
            "activity": [
                {
                    "ec_number": "3.6.5.2",
                    "activity": "GTP + H2O = GDP + H(+) + phosphate.",
                    "evidence": [
                        {
                            "id": "P08644",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08644"
                        }
                    ]
                },
                {
                    "ec_number": "3.6.5.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P08644",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08644"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P08922",
            "gene_name": "ROS1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P08922",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08922"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P08922",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08922"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P08923",
            "gene_name": "Ltk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P08923",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08923"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P08923",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P08923"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P09208",
            "gene_name": "InR",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P09208",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09208"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P09208",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09208"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P09215",
            "gene_name": "Prkcd",
            "activity": [
                {
                    "ec_number": "2.7.11.13",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P09215",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09215"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.13",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P09215",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09215"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P09581",
            "gene_name": "Csf1r",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P09581",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09581"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P09619",
            "gene_name": "PDGFRB",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P09619",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09619"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P09619",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09619"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P09759",
            "gene_name": "Ephb1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P09759",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09759"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P09759",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09759"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P09760",
            "gene_name": "Fer",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P09760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09760"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P09760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09760"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P09769",
            "gene_name": "FGR",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P09769",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09769"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P09769",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P09769"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P0C1S8",
            "gene_name": "WEE2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P0C1S8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P0C1S8"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P0C1S8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P0C1S8"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P10686",
            "gene_name": "Plcg1",
            "activity": [
                {
                    "ec_number": "3.1.4.11",
                    "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).",
                    "evidence": [
                        {
                            "id": "P10686",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P10686"
                        }
                    ]
                },
                {
                    "ec_number": "3.1.4.11",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P10686",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P10686"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P10721",
            "gene_name": "KIT",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P10721",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P10721"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P10721",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P10721"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P11275",
            "gene_name": "Camk2a",
            "activity": [
                {
                    "ec_number": "2.7.11.17",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P11275",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11275"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.17",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P11275",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11275"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P11362",
            "gene_name": "FGFR1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P11362",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11362"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P11362",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11362"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P11730",
            "gene_name": "Camk2g",
            "activity": [
                {
                    "ec_number": "2.7.11.17",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P11730",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11730"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.17",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P11730",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11730"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P11980",
            "gene_name": "Pkm",
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                {
                    "ec_number": "2.7.1.40",
                    "activity": "CTP + pyruvate = CDP + H(+) + phosphoenolpyruvate.",
                    "evidence": [
                        {
                            "id": "P11980",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11980"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.40",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P11980",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11980"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P11980",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11980"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P11980",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P11980"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P12931",
            "gene_name": "SRC",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P12931",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P12931"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P12931",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P12931"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P13368",
            "gene_name": "sev",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P13368",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P13368"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P13368",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P13368"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P14234",
            "gene_name": "Fgr",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P14234",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14234"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P14234",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14234"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P14616",
            "gene_name": "INSRR",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P14616",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14616"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P14616",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14616"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P14618",
            "gene_name": "PKM",
            "activity": [
                {
                    "ec_number": "2.7.1.40",
                    "activity": "CTP + pyruvate = CDP + H(+) + phosphoenolpyruvate.",
                    "evidence": [
                        {
                            "id": "P14618",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14618"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.40",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P14618",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P14618"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        }
                    ]
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                {
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                {
                    "ec_number": "2.7.12.1",
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                            "url": "https://www.uniprot.org/uniprot/P14680"
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                {
                    "ec_number": "2.7.10.1",
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                {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                {
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                            "id": "P15208",
                            "database": "UniProtKB",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                {
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P15209"
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                {
                    "ec_number": "2.7.11.17",
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                    ]
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                {
                    "ec_number": "2.7.11.17",
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                            "url": "https://www.uniprot.org/uniprot/P15791"
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                }
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                {
                    "ec_number": "2.7.10.1",
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                    ]
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                {
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                    "ec_number": "2.7.10.1",
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "P16092",
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                {
                    "ec_number": "2.7.10.1",
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                            "url": "https://www.uniprot.org/uniprot/P16234"
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                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P16234",
                            "database": "UniProtKB",
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                {
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P16277",
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                            "url": "https://www.uniprot.org/uniprot/P16277"
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.2",
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                            "id": "P18160",
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                    "ec_number": "2.7.10.2",
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                            "id": "P18161",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P18161",
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                    "ec_number": "2.7.10.1",
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                            "id": "P18475",
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P18475",
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                    "ec_number": "2.7.10.2",
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                            "id": "P19525",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                            "id": "P21709",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                    "ec_number": "2.7.12.1",
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                            "id": "P21965",
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P22455",
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                    "ec_number": "2.7.12.1",
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                            "id": "P22518",
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                {
                    "ec_number": "2.7.12.1",
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        {
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "url": "https://www.uniprot.org/uniprot/P22607"
                        }
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                    "ec_number": "2.7.10.2",
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                            "url": "https://www.uniprot.org/uniprot/P23458"
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                {
                    "ec_number": "2.7.10.2",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P23458"
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P24062"
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                {
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                            "id": "P24062",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P24062"
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P24604"
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P24604",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P24604"
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                    "ec_number": "2.7.10.2",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P25911",
                            "database": "UniProtKB",
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                    "ec_number": "2.7.10.1",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P26618"
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                {
                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.2",
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                    ]
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                {
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                            "id": "P28867",
                            "database": "UniProtKB",
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                {
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                            "id": "P28867",
                            "database": "UniProtKB",
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P29317",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29317"
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                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P29317",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29317"
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P29319",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29319"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P29319",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29319"
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29320"
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                {
                    "ec_number": "2.7.10.1",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29320"
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P29321",
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                            "url": "https://www.uniprot.org/uniprot/P29321"
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                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "url": "https://www.uniprot.org/uniprot/P29321"
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                    "ec_number": "2.7.10.1",
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                            "url": "https://www.uniprot.org/uniprot/P29322"
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                {
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                    "ec_number": "2.7.10.1",
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                    ]
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                {
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                            "id": "P29376",
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                            "url": "https://www.uniprot.org/uniprot/P29376"
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                    ]
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                {
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                    "ec_number": "2.7.10.2",
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                            "url": "https://www.uniprot.org/uniprot/P29597"
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.2",
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                            "id": "P30291",
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                            "url": "https://www.uniprot.org/uniprot/P30291"
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P30291",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P30530",
                            "database": "UniProtKB",
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                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P30530",
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "P31938",
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                    ]
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "P31938",
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                {
                    "ec_number": "2.7.12.1",
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                            "id": "P32350",
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                            "id": "P32350",
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "P32490",
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                {
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                            "id": "P32490",
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                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P32491",
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                    "ec_number": "2.7.12.2",
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                            "id": "P32491",
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                    "ec_number": "2.7.10.2",
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                            "id": "P32577",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P32577",
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                    "ec_number": "2.7.12.1",
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                            "id": "P33981",
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                {
                    "ec_number": "2.7.12.1",
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                            "id": "P33981",
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                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.2",
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                            "id": "P34152",
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                    "ec_number": "2.7.10.1",
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                            "id": "P34925",
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                {
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                            "id": "P34925",
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                    "ec_number": "2.7.10.1",
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                            "id": "P35546",
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                {
                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "url": "https://www.uniprot.org/uniprot/P35590"
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                    ]
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                {
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                            "id": "P35590",
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P35739",
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "P35739",
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                            "url": "https://www.uniprot.org/uniprot/P35739"
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                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P35761",
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                    ]
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                {
                    "ec_number": "2.7.12.1",
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                            "id": "P35761",
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                    ]
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        {
            "uniprot_ac": "P35790",
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                {
                    "ec_number": "2.7.1.32",
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                        {
                            "id": "P35790",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35790"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.82",
                    "activity": "ATP + ethanolamine = ADP + H(+) + phosphoethanolamine.",
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                            "id": "P35790",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35790"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.32",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P35790",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35790"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P35916",
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P35916",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35916"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P35916",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35916"
                        }
                    ]
                }
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
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                            "id": "P35917",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35917"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P35917",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35917"
                        }
                    ]
                }
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P35918",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35918"
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P35918",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35918"
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                }
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P35968",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35968"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
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                        {
                            "id": "P35968",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35968"
                        }
                    ]
                }
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        },
        {
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                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P35969",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35969"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                        {
                            "id": "P35969",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35969"
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                }
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P35991",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35991"
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                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                            "id": "P35991",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P35991"
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                    ]
                }
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        {
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                {
                    "ec_number": "2.7.12.2",
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                    "evidence": [
                        {
                            "id": "P36506",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P36506"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
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                            "id": "P36506",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P36506"
                        }
                    ]
                }
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                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P36507",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P36507"
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                    ]
                },
                {
                    "ec_number": "2.7.12.2",
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                        {
                            "id": "P36507",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P36507"
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                }
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P36888",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P36888"
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                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P36888",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P39688",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P39688"
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P39688",
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                            "url": "https://www.uniprot.org/uniprot/P39688"
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                    "ec_number": "2.7.10.2",
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                            "id": "P41240",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P41240",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P41241",
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                            "url": "https://www.uniprot.org/uniprot/P41241"
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P41241",
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P41242",
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                            "url": "https://www.uniprot.org/uniprot/P41242"
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P41242",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P41243",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                        {
                            "id": "P41243",
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                    ]
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                {
                    "ec_number": "3.1.3.48",
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                        {
                            "id": "P41499",
                            "database": "UniProtKB",
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                    ]
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                {
                    "ec_number": "3.1.3.48",
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                            "id": "P41499",
                            "database": "UniProtKB",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P42679",
                            "database": "UniProtKB",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                        {
                            "id": "P42679",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P42679"
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                }
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P42680",
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                            "url": "https://www.uniprot.org/uniprot/P42680"
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P42680",
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                    "ec_number": "2.7.10.2",
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                            "id": "P42681",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P42681",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P42682",
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                            "url": "https://www.uniprot.org/uniprot/P42682"
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P42682",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P42684",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P42684"
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P42684",
                            "database": "UniProtKB",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P42685",
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                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                            "id": "P42685",
                            "database": "UniProtKB",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P43403",
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                            "url": "https://www.uniprot.org/uniprot/P43403"
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                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                            "id": "P43403",
                            "database": "UniProtKB",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P43404",
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                            "url": "https://www.uniprot.org/uniprot/P43404"
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                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                            "id": "P43404",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P43405",
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                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P43405",
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                    "ec_number": "2.7.12.2",
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                            "id": "P45985",
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                    ]
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "P45985",
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                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P46734",
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                            "url": "https://www.uniprot.org/uniprot/P46734"
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                    ]
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                {
                    "ec_number": "2.7.12.2",
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                            "id": "P46734",
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                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "P47809",
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                    ]
                },
                {
                    "ec_number": "2.7.12.2",
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                            "id": "P47809",
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                    ]
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            ]
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            "uniprot_ac": "P47810",
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P47810",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P47810"
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                    ]
                },
                {
                    "ec_number": "2.7.10.2",
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                            "id": "P47810",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P47810"
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                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P48025",
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                {
                    "ec_number": "2.7.10.2",
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                    "evidence": [
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                            "id": "P48025",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P48025"
                        }
                    ]
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                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
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                            "id": "P48025",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P48025"
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                {
                    "ec_number": "2.7.12.1",
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                    "evidence": [
                        {
                            "id": "P49657",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P49657"
                        }
                    ]
                },
                {
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                        {
                            "id": "P49657",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P49657"
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                }
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                {
                    "ec_number": "2.7.12.1",
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                            "id": "P49759",
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                            "url": "https://www.uniprot.org/uniprot/P49759"
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                    ]
                },
                {
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                    "ec_number": "2.7.12.1",
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                            "id": "P49760",
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                            "url": "https://www.uniprot.org/uniprot/P49760"
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                {
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                {
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                {
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                {
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P50545",
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                            "url": "https://www.uniprot.org/uniprot/P50545"
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                {
                    "ec_number": "2.7.10.2",
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                {
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                            "id": "P51451",
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                {
                    "ec_number": "2.7.10.2",
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                        }
                    ]
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                {
                    "ec_number": "2.7.10.2",
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                            "id": "P51813",
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                    "ec_number": "2.7.10.2",
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                {
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                            "id": "P52332",
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                    "ec_number": "2.7.10.2",
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                {
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                    ]
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                            "id": "P53767",
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                    ]
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                {
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                    "ec_number": "2.7.12.2",
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                            "id": "P54199",
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                {
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                            "id": "P54756",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                            "id": "P54761",
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P54762",
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                            "url": "https://www.uniprot.org/uniprot/P54762"
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P54762",
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                        {
                            "id": "P54763",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P54763"
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                            "id": "P54763",
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                    ]
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                    "ec_number": "2.7.10.1",
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                            "id": "P54764",
                            "database": "UniProtKB",
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                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P54764",
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                            "url": "https://www.uniprot.org/uniprot/P54764"
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                    ]
                }
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                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "P55144",
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                    ]
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                {
                    "ec_number": "2.7.10.1",
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                            "id": "P55144",
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                    ]
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        {
            "uniprot_ac": "P55146",
            "gene_name": "Tyro3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P55146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P55146"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P55146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P55146"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P57097",
            "gene_name": "Mertk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P57097",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P57097"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P57097",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P57097"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P57760",
            "gene_name": "Stk16",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P57760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P57760"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P57760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P57760"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P57760",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P57760"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P58801",
            "gene_name": "Ripk2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P58801",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P58801"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P58801",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P58801"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P58801",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P58801"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P70236",
            "gene_name": "Map2k6",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P70236",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70236"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P70236",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70236"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P70424",
            "gene_name": "Erbb2",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P70424",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70424"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P70424",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70424"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P70451",
            "gene_name": "Fer",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P70451",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70451"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P70451",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70451"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P70600",
            "gene_name": "Ptk2b",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P70600",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70600"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P70600",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P70600"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P83102",
            "gene_name": "Dyrk3",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "P83102",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P83102"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P83102",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P83102"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P97504",
            "gene_name": "Bmx",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P97504",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97504"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P97504",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97504"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P97523",
            "gene_name": "Met",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P97523",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97523"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P97523",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97523"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "P97793",
            "gene_name": "Alk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "P97793",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97793"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "P97793",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P97793"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q00342",
            "gene_name": "Flt3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q00342",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00342"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q00342",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00342"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q00495",
            "gene_name": "Csf1r",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q00495",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00495"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q00495",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00495"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q00993",
            "gene_name": "Axl",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q00993",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00993"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q00993",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q00993"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01134",
            "gene_name": "Chka",
            "activity": [
                {
                    "ec_number": "2.7.1.32",
                    "activity": "ATP + choline = ADP + H(+) + phosphocholine.",
                    "evidence": [
                        {
                            "id": "Q01134",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01134"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.82",
                    "activity": "ATP + ethanolamine = ADP + H(+) + phosphoethanolamine.",
                    "evidence": [
                        {
                            "id": "Q01134",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01134"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.1.32",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01134",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01134"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01279",
            "gene_name": "Egfr",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q01279",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01279"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01279",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01279"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01621",
            "gene_name": "Lck",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q01621",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01621"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01621",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01621"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01887",
            "gene_name": "Ryk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q01887",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01887"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01887",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01887"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01974",
            "gene_name": "ROR2",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q01974",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01974"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01974",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01974"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q01986",
            "gene_name": "Map2k1",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q01986",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01986"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q01986",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q01986"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q02750",
            "gene_name": "MAP2K1",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q02750",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q02750"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q02750",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q02750"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q02763",
            "gene_name": "TEK",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q02763",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q02763"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q02763",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q02763"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q02858",
            "gene_name": "Tek",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q02858",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q02858"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q02858",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q02858"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q03137",
            "gene_name": "Epha4",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q03137",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03137"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03137",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03137"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q03142",
            "gene_name": "Fgfr4",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q03142",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03142"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03142",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03142"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q03145",
            "gene_name": "Epha2",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q03145",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03145"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03145",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03145"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q03146",
            "gene_name": "Ddr1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q03146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03146"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03146",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03146"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q03348",
            "gene_name": "Ptpra",
            "activity": [
                {
                    "ec_number": "3.1.3.48",
                    "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.",
                    "evidence": [
                        {
                            "id": "Q03348",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03348"
                        }
                    ]
                },
                {
                    "ec_number": "3.1.3.48",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03348",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03348"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q03351",
            "gene_name": "Ntrk3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q03351",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03351"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03351",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03351"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q03526",
            "gene_name": "Itk",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q03526",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03526"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03526",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03526"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q03963",
            "gene_name": "Eif2ak2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q03963",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03963"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q03963",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03963"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q03963",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q03963"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q04589",
            "gene_name": "Fgfr1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q04589",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q04589"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q04589",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q04589"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q04736",
            "gene_name": "Yes1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q04736",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q04736"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q04736",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q04736"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q04912",
            "gene_name": "MST1R",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q04912",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q04912"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q04912",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q04912"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q04970",
            "gene_name": "Nras",
            "activity": [
                {
                    "ec_number": "3.6.5.2",
                    "activity": "GTP + H2O = GDP + H(+) + phosphate.",
                    "evidence": [
                        {
                            "id": "Q04970",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q04970"
                        }
                    ]
                },
                {
                    "ec_number": "3.6.5.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q04970",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q04970"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q05030",
            "gene_name": "Pdgfrb",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q05030",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q05030"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q05030",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q05030"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q05397",
            "gene_name": "PTK2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q05397",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q05397"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q05397",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q05397"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q05655",
            "gene_name": "PRKCD",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q05655",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q05655"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.13",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q05655",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q05655"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.13",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q05655",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q05655"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q06187",
            "gene_name": "BTK",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q06187",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q06187"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q06187",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q06187"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q06418",
            "gene_name": "TYRO3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q06418",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q06418"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q06418",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q06418"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q06806",
            "gene_name": "Tie1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q06806",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q06806"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q06806",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q06806"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q07014",
            "gene_name": "Lyn",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q07014",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07014"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q07014",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07014"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q07407",
            "gene_name": "htl",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q07407",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07407"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q07407",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07407"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q07912",
            "gene_name": "TNK2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q07912",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07912"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q07912",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07912"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q07912",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07912"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q07912",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q07912"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q08345",
            "gene_name": "DDR1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q08345",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q08345"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q08345",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q08345"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q08881",
            "gene_name": "ITK",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q08881",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q08881"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q08881",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q08881"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q09147",
            "gene_name": "btl",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q09147",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q09147"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q09147",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q09147"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q12866",
            "gene_name": "MERTK",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q12866",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q12866"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q12866",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q12866"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q13163",
            "gene_name": "MAP2K5",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q13163",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13163"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q13163",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13163"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q13470",
            "gene_name": "TNK1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q13470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13470"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q13470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13470"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q13627",
            "gene_name": "DYRK1A",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q13627",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13627"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q13627",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13627"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.23",
                    "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].",
                    "evidence": [
                        {
                            "id": "Q13627",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13627"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.23",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q13627",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13627"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q13882",
            "gene_name": "PTK6",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q13882",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13882"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q13882",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q13882"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q14289",
            "gene_name": "PTK2B",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q14289",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q14289"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q14289",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q14289"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q14680",
            "gene_name": "MELK",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
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                            "url": "https://www.uniprot.org/uniprot/Q15303"
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                            "url": "https://www.uniprot.org/uniprot/Q15375"
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                    "ec_number": "2.7.10.1",
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                            "database": "UniProtKB",
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                {
                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.1",
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                            "url": "https://www.uniprot.org/uniprot/Q16832"
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                {
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                {
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q23977"
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                            "url": "https://www.uniprot.org/uniprot/Q23977"
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                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.10.2",
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                            "id": "Q54I36",
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                    "ec_number": "2.7.10.1",
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                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "id": "Q54R58",
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                {
                    "ec_number": "2.7.10.2",
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                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                    "ec_number": "2.7.12.1",
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        },
        {
            "uniprot_ac": "Q55CL6",
            "gene_name": "mekA",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q55CL6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q55CL6"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q55CL6",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q55CL6"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q5FVG7",
            "gene_name": "Srms",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q5FVG7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5FVG7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q5FVG7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5FVG7"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q5JZY3",
            "gene_name": "EPHA10",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q5JZY3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5JZY3"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q5JZY3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5JZY3"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q5RJI4",
            "gene_name": "Pkdcc",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q5RJI4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5RJI4"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q5RJI4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5RJI4"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q5U2X5",
            "gene_name": "Tnk2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q5U2X5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U2X5"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q5U2X5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U2X5"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q5U2X5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U2X5"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q5U2X5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U2X5"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q5U4C9",
            "gene_name": "Dyrk2",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q5U4C9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U4C9"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q5U4C9",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U4C9"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q60629",
            "gene_name": "Epha5",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q60629",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60629"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q60629",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60629"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q60750",
            "gene_name": "Epha1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q60750",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60750"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q60750",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60750"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q60751",
            "gene_name": "Igf1r",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q60751",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60751"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q60751",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60751"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q60805",
            "gene_name": "Mertk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q60805",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60805"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q60805",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q60805"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61006",
            "gene_name": "Musk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61006",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61006"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61006",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61006"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61214",
            "gene_name": "Dyrk1a",
            "activity": [
                {
                    "ec_number": "2.7.11.23",
                    "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].",
                    "evidence": [
                        {
                            "id": "Q61214",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61214"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61214",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61214"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61214",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61214"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.23",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61214",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61214"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61526",
            "gene_name": "Erbb3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61526",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61526"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61526",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61526"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61527",
            "gene_name": "Erbb4",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61527",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61527"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61527",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61527"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61772",
            "gene_name": "Epha7",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61772",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61772"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61772",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61772"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61846",
            "gene_name": "Melk",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61846",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61846"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61846",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61846"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61846",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61846"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q61851",
            "gene_name": "Fgfr3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q61851",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61851"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q61851",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61851"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62120",
            "gene_name": "Jak2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62120",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62120"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62120",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62120"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62137",
            "gene_name": "Jak3",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62137",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62137"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62137",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62137"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62190",
            "gene_name": "Mst1r",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62190",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62190"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62190",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62190"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62270",
            "gene_name": "Srms",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62270",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62270"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62270",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62270"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62371",
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            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62371",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62371"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62371",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62371"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62413",
            "gene_name": "Epha6",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62413",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62413"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62413",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62413"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62611",
            "gene_name": "Il1rl1",
            "activity": [
                {
                    "ec_number": "3.2.2.6",
                    "activity": "H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide.",
                    "evidence": [
                        {
                            "id": "Q62611",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62611"
                        }
                    ]
                },
                {
                    "ec_number": "3.2.2.6",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62611",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62611"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62662",
            "gene_name": "Frk",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62662",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62662"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62662",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62662"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62689",
            "gene_name": "Jak2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62689",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62689"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62689",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62689"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62799",
            "gene_name": "Erbb3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62799",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62799"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62799",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62799"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62838",
            "gene_name": "Musk",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62838",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62838"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62838",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62838"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62844",
            "gene_name": "Fyn",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62844",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62844"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62844",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62844"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62862",
            "gene_name": "Map2k5",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62862",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62862"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62862",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62862"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q62956",
            "gene_name": "Erbb4",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q62956",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62956"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q62956",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q62956"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63116",
            "gene_name": "Kit",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63116",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63116"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63116",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63116"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63117",
            "gene_name": "Clk3",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63117",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63117"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63117",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63117"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63132",
            "gene_name": "Ros1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63132",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63132"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63132",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63132"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63184",
            "gene_name": "Eif2ak2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63184",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63184"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63184",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63184"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63184",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63184"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63272",
            "gene_name": "Jak3",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63272",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63272"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63272",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63272"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63470",
            "gene_name": "Dyrk1a",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63470"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63470"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.23",
                    "activity": "[DNA-directed RNA polymerase] + ATP = ADP + H(+) + phospho-[DNA-directed RNA polymerase].",
                    "evidence": [
                        {
                            "id": "Q63470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63470"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.11.23",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63470",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63470"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63474",
            "gene_name": "Ddr1",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63474",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63474"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63474",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63474"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63572",
            "gene_name": "Tesk1",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63572",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63572"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63572",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63572"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63604",
            "gene_name": "Ntrk2",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63604",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63604"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63604",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63604"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63621",
            "gene_name": "Il1rap",
            "activity": [
                {
                    "ec_number": "3.2.2.6",
                    "activity": "H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide.",
                    "evidence": [
                        {
                            "id": "Q63621",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63621"
                        }
                    ]
                },
                {
                    "ec_number": "3.2.2.6",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63621",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63621"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63802",
            "gene_name": "Wee1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63802",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63802"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63802",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63802"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q63932",
            "gene_name": "Map2k2",
            "activity": [
                {
                    "ec_number": "2.7.12.2",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q63932",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63932"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q63932",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q63932"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q64434",
            "gene_name": "Ptk6",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q64434",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64434"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q64434",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64434"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q64716",
            "gene_name": "Insrr",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q64716",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64716"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q64716",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64716"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q64725",
            "gene_name": "Syk",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q64725",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64725"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q64725",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q64725"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q66JT0",
            "gene_name": "Wee2",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q66JT0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q66JT0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q66JT0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q66JT0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6J9G0",
            "gene_name": "STYK1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6J9G0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6J9G0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6J9G0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6J9G0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6J9G1",
            "gene_name": "Styk1",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6J9G1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6J9G1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6J9G1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6J9G1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6P6U0",
            "gene_name": "Fgr",
            "activity": [
                {
                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6P6U0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6P6U0"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6P6U0",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6P6U0"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6RUV5",
            "gene_name": "Rac1",
            "activity": [
                {
                    "ec_number": "3.6.5.2",
                    "activity": "GTP + H2O = GDP + H(+) + phosphate.",
                    "evidence": [
                        {
                            "id": "Q6RUV5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6RUV5"
                        }
                    ]
                },
                {
                    "ec_number": "3.6.5.2",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6RUV5",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6RUV5"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6VNS1",
            "gene_name": "Ntrk3",
            "activity": [
                {
                    "ec_number": "2.7.10.1",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6VNS1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6VNS1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.10.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6VNS1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6VNS1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6XUX1",
            "gene_name": "Dstyk",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6XUX1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6XUX1"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6XUX1",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6XUX1"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6XUX2",
            "gene_name": "Dstyk",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
                    "evidence": [
                        {
                            "id": "Q6XUX2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6XUX2"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.12.1",
                    "activity": "",
                    "evidence": [
                        {
                            "id": "Q6XUX2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6XUX2"
                        }
                    ]
                }
            ]
        },
        {
            "uniprot_ac": "Q6XUX3",
            "gene_name": "DSTYK",
            "activity": [
                {
                    "ec_number": "2.7.12.1",
                    "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].",
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                            "id": "Q6XUX3",
                            "database": "UniProtKB",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6XUX3"
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                            "url": "https://www.uniprot.org/uniprot/Q75JK0"
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                {
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                {
                    "ec_number": "2.7.12.1",
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                            "url": "https://www.uniprot.org/uniprot/Q76NV1"
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                {
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                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                    "ec_number": "2.7.10.2",
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                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                    "ec_number": "2.7.10.2",
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                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                {
                    "ec_number": "2.7.10.1",
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                    "ec_number": "2.7.10.2",
                    "activity": "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein].",
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                            "database": "UniProtKB",
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                {
                    "ec_number": "2.7.10.2",
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                    ]
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        },
        {
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                    "ec_number": "2.7.10.1",
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                {
                    "ec_number": "2.7.10.1",
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                    ]
                },
                {
                    "ec_number": "2.7.10.1",
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                        }
                    ]
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                {
                    "ec_number": "2.7.10.1",
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                {
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                {
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                {
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                {
                    "ec_number": "2.7.10.1",
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                {
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                {
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