{ "uniprot_canonical_ac": "P14148-1", "uniprot_ac": "P14148", "uniprot_id": "RL7_MOUSE", "mass": { "chemical_mass": 31420.0, "monoisotopic_mass": 31420.0 }, "refseq": { "ac": "NP_035421", "name": "large ribosomal subunit protein uL30", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_035421" }, "gene_names": [ { "name": "Rpl7", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P14148", "id": "P14148" }, { "name": "Rpl7a; Surf-3", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_035421", "id": "NP_035421" }, { "name": "Rpl7", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_035421", "id": "NP_035421" } ], "protein_names": [ { "name": "Large ribosomal subunit protein uL30", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P14148" }, { "name": "60S ribosomal protein L7", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_035421", "id": "NP_035421" }, { "name": "60S ribosomal protein L7", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "P14148" }, { "name": "large ribosomal subunit protein uL30", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_035421", "id": "NP_035421" } ], "function": [ { "annotation": "Component of the large ribosomal subunit (PubMed:36517592). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592). Binds to G-rich structures in 28S rRNA and in mRNAs (By similarity). Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148#function" }, { "database": "UniProtKB", "id": "P18124", "url": "https://www.uniprot.org/uniprot/P18124#function" }, { "database": "PubMed", "id": "36517592", "url": "https://glygen.org/publication/PubMed/36517592" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Rpl7", "url": "https://www.uniprot.org/uniprot/P14148", "locus": { "chromosome": "1", "start_pos": 16171519, "end_pos": 16174886, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000043716", "url": "https://www.ensembl.org/id/ENSMUSG00000043716" } ] } } ], "crossref": [ { "id": "ENSMUSG00000043716", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000043716", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01657", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01657", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "19989", "url": "https://www.ncbi.nlm.nih.gov/gene/19989", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "P14148", "url": "https://www.ebi.ac.uk/intact/interactors/id:P14148*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR005998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012988", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012988", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:19989", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:19989", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "98073", "url": "http://www.informatics.jax.org/marker/MGI:98073", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "P14148", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P14148", "database": "O-GlcNAc Database", "categories": [ "Glycoproteomics" ] }, { "id": "TKKTNHF", "url": "https://omabrowser.org/oma/group/TKKTNHF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "167701at2759", "url": "http://www.orthodb.org/?query=167701at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11524", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11524", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11524:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11524:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "6SWA", "url": "https://www.rcsb.org/structure/6SWA", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7CPU", "url": "https://www.rcsb.org/structure/7CPU", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7CPV", "url": "https://www.rcsb.org/structure/7CPV", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7LS1", "url": "https://www.rcsb.org/structure/7LS1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "7LS2", "url": "https://www.rcsb.org/structure/7LS2", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00327", "url": "http://pfam.xfam.org/family/PF00327", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF08079", "url": "http://pfam.xfam.org/family/PF08079", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_P14148", "url": "http://purl.obolibrary.org/obo/PR_P14148", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-MMU-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-156827", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-1799339", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6791226", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-72689", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-72706", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-975956", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-975957", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_035421", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_035421", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6XI62", "url": "https://www.uniprot.org/uniprot/F6XI62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6XI62-1", "url": "https://www.uniprot.org/uniprot/F6XI62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P14148-1", "url": "https://www.uniprot.org/uniprot/P14148-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAVPEKKKKVATVPGTLKKKVPAGPKTLKKKVPAVPETLKKKRRNFAELKVKRLRKKFALKTLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNSLIARSLGKFGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQINRLIRRMN", "length": 270, "header": "sp|P14148-1|RL7_MOUSE Isoform 1 of Large ribosomal subunit protein uL30 OS=Mus musculus OX=10090 GN=Rpl7 PE=1 SV=2 CANONICAL=P14148-1" }, "isoforms": [ { "isoform_ac": "F6XI62-1", "url": "", "sequence": { "sequence": "XEGVRGASARRPWQYQEQTEGRLRIRLLGRREKKKKVATVPGTLKKKVPAGPKTLKKKVPAVPETLKKKRRNFAELKVKRLRKKFALKTLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNSLIARSLGKFGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGMKKKTTHFVEGG", "length": 279, "header": "tr|F6XI62-1|RL7_MOUSE Computationally mapped isoform of Large ribosomal subunit protein uL30 OS=Mus musculus OX=10090 GN=Rpl7 PE=1 SV=1 CANONICAL=P14148-1" }, "locus": { "chromosome": "1", "start_pos": 16174451, "end_pos": 16172005, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000149566.2", "url": "https://www.ensembl.org/id/ENSMUST00000149566.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000118695.2", "url": "https://www.ensembl.org/id/ENSMUSP00000118695.2" } ] } }, { "isoform_ac": "P14148-1", "url": "", "sequence": { "sequence": "MEAVPEKKKKVATVPGTLKKKVPAGPKTLKKKVPAVPETLKKKRRNFAELKVKRLRKKFALKTLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNSLIARSLGKFGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQINRLIRRMN", "length": 270, "header": "sp|P14148-1|RL7_MOUSE Isoform 1 of Large ribosomal subunit protein uL30 OS=Mus musculus OX=10090 GN=Rpl7 PE=1 SV=2 CANONICAL=P14148-1" }, "locus": { "chromosome": "1", "start_pos": 16174602, "end_pos": 16171955, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000058437", "url": "https://www.ensembl.org/id/ENSMUST00000058437" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000071616", "url": "https://www.ensembl.org/id/ENSMUSP00000071616" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "evidence": [ { "id": "P14148", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P14148" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "phosphorylation": [ { "start_pos": 161, "end_pos": 161, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "site_lbl": "Tyr161" }, { "start_pos": 39, "end_pos": 39, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "site_lbl": "Thr39" } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "The mouse ribosomal protein L7 gene. Its primary structure and functional analysis of the promoter region.", "journal": "J. Biol. Chem.", "date": "1990", "authors": "Meyuhas O, Klein A", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "reference": [ { "type": "PubMed", "id": "2365680", "url": "https://glygen.org/publication/PubMed/2365680" } ] }, { "title": "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.", "journal": "Mol. Cell", "date": "2013", "authors": "Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y", "evidence": [ { "database": "UniProtKB", "id": "F6XI62", "url": "https://www.uniprot.org/uniprot/F6XI62" }, { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "reference": [ { "type": "PubMed", "id": "23806337", "url": "https://glygen.org/publication/PubMed/23806337" } ] }, { "title": "The DHX33 RNA Helicase Promotes mRNA Translation Initiation.", "journal": "Mol. Cell. Biol.", "date": "2015", "authors": "Zhang Y, You J, Wang X, Weber J", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "reference": [ { "type": "PubMed", "id": "26100019", "url": "https://glygen.org/publication/PubMed/26100019" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P14148", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P14148" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "P14148", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P14148" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "Structural and functional properties of ribosomal protein L7 from humans and rodents.", "journal": "Nucleic Acids Res.", "date": "1993", "authors": "Hemmerich P., von Mikecz A., Neumann F., Krawinkel U., Soezen O., Wolff-Vorbeck G., Zoebelein R.", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "reference": [ { "type": "PubMed", "id": "8441630", "url": "https://glygen.org/publication/PubMed/8441630" } ] } ], "pathway": [ { "id": "mmu:19989", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:19989", "resource": "KEGG Pathway" }, { "id": "R-MMU-156827", "name": "L13a-mediated translational silencing of Ceruloplasmin expression", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-MMU-1799339", "name": "SRP-dependent cotranslational protein targeting to membrane", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-MMU-6791226", "name": "Major pathway of rRNA processing in the nucleolus and cytosol", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-MMU-72689", "name": "Formation of a pool of free 40S subunits", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-MMU-72706", "name": "GTP hydrolysis and joining of the 60S ribosomal subunit", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-MMU-975956", "name": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-MMU-975957", "name": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" } ], "orthologs": [ { "uniprot_canonical_ac": "P18124-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "RPL7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGVEEKKKEVPAVPETLKKKRRNFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNALIARSLGKYGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQINRLIRRMN", "length": 248 }, "evidence": [ { "id": "45226203", "url": "http://www.informatics.jax.org/homology/45226203", "database": "MGI" }, { "id": "P14148", "url": "https://omabrowser.org/oma/group/P14148/", "database": "OMA" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "P32100-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "RpL7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPAPVVKKPAAKKLPAVPESKLKFSKKQISKRVAESKRRLKKAAVIALRKKENLVRAEKYQNEYIKAEQREIKLRRLAKKRNQFYVPAEAKLAFVVRIRGINKVAPKVRKVLQLFRLRQINNGVFIKLNKATINMLRIAEPYITWGYPNLKSVRELIYKRGFVKHNRQRVPITDNFVIERKLRQAHQIQCVEDLVHEIFTVGPNFKYASNFLWPFKLNTPTGGWRKKANHYVNGGDFGNREDQINRLLRKMV", "length": 252 }, "evidence": [ { "id": "P14148", "url": "https://omabrowser.org/oma/group/P14148/", "database": "OMA" } ], "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q12213-1", "protein_name": "Large ribosomal subunit protein uL30B", "gene_name": "RPL7B", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTEKILTPESQLKKTKAQQKTAEQIAAERAARKAANKEKRAIILERNAAYQKEYETAERNIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVTKATLELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQRVPLSDNAIIEANLGKYGILSIDDLIHEIITVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLVKAMN", "length": 244 }, "evidence": [ { "id": "P14148", "url": "https://omabrowser.org/oma/group/P14148/", "database": "OMA" } ], "common_name": "Yeast" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "5S rRNA binding", "id": "GO:0008097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008097", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "cytosolic ribosome", "id": "GO:0022626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022626", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "polysome", "id": "GO:0005844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005844", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "A band", "id": "GO:0031672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031672", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "translation at presynapse", "id": "GO:0140236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140236", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" }, { "name": "translation at postsynapse", "id": "GO:0140242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140242", "evidence": [ { "database": "UniProtKB", "id": "P14148", "url": "https://www.uniprot.org/uniprot/P14148" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }