{
    "uniprot_canonical_ac": "P11985-1",
    "uniprot_ac": "P11985",
    "uniprot_id": "DYLT2_MOUSE",
    "mass": {
        "chemical_mass": 22379.0,
        "monoisotopic_mass": 22379.0
    },
    "refseq": {
        "ac": "NP_001116839",
        "name": "t-complex-associated testis expressed 3-like isoform 1",
        "summary": "This gene is one of three genes with a very high degree of similarity to each other within a 77 kb genomic span on Chromosome 17 A2. This gene lies between the other two gene copies. [provided by RefSeq, Jul 2008].",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116839"
    },
    "gene_names": [
        {
            "name": "Dynlt2a1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/P11985",
            "id": "P11985"
        },
        {
            "name": "Dynlt2a2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/P11985",
            "id": "P11985"
        },
        {
            "name": "Dynlt2a3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/P11985",
            "id": "P11985"
        },
        {
            "name": "Dynlt2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/P11985",
            "id": "P11985"
        },
        {
            "name": "100041639; Dynlt2; Dynlt2b; Gm3448; LC2; Tcte-3; Tcte3; TCTEX-2; TCTEX-4; Tctex1d3; Tctex2; Tctex4",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116839",
            "id": "NP_001116839"
        },
        {
            "name": "Dynlt2a2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116839",
            "id": "NP_001116839"
        },
        {
            "name": "Dynlt2a2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/P11985",
            "id": "P11985"
        },
        {
            "name": "Tcte3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/P11985",
            "id": "P11985"
        },
        {
            "name": "Tctex1d3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/P11985",
            "id": "P11985"
        },
        {
            "name": "Tctex2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/P11985",
            "id": "P11985"
        },
        {
            "name": "Tctex4",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/P11985",
            "id": "P11985"
        }
    ],
    "protein_names": [
        {
            "name": "Dynein light chain Tctex-type protein 2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "P11985"
        },
        {
            "name": "LC2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P11985"
        },
        {
            "name": "T-complex testis-specific protein 2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P11985"
        },
        {
            "name": "T-complex testis-specific protein 3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P11985"
        },
        {
            "name": "T-complex-associated testis-expressed protein 3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P11985"
        },
        {
            "name": "T-complex-associated testis-expressed protein 4",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P11985"
        },
        {
            "name": "TCTEX-2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P11985"
        },
        {
            "name": "TCTEX-4",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P11985"
        },
        {
            "name": "Tcte-3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P11985"
        },
        {
            "name": "Tctex1 domain-containing protein 3; T-complex testis-specific protein 2; T-complex testis-specific protein 3; T-complex-associated testis-expressed protein 3; T-complex-associated testis-expressed protein 4; dynein light chain Tctex-type 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116839",
            "id": "NP_001116839"
        },
        {
            "name": "Tctex1 domain-containing protein 3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P11985"
        },
        {
            "name": "t-complex-associated testis expressed 3-like isoform 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116839",
            "id": "NP_001116839"
        }
    ],
    "function": [
        {
            "annotation": "May be an accessory component of axonemal dynein and cytoplasmic dynein 1. Candidate for involvement in male sterility.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P11985",
                    "url": "https://www.uniprot.org/uniprot/P11985#function"
                },
                {
                    "database": "PubMed",
                    "id": "11278908",
                    "url": "https://glygen.org/publication/PubMed/11278908"
                }
            ]
        },
        {
            "annotation": "This gene is one of three genes with a very high degree of similarity to each other within a 77 kb genomic span on Chromosome 17 A2. This gene lies between the other two gene copies. [provided by RefSeq, Jul 2008].",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001116839",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116839"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P11985",
                    "url": "https://www.uniprot.org/uniprot/P11985"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Dynlt2",
            "url": "https://www.uniprot.org/uniprot/P11985",
            "locus": {}
        }
    ],
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        {
            "id": "ENSMUSG00000079707",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000079707",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "ENSMUSG00000079710",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000079710",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "ENSMUSG00000116780",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000116780",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd21460",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21460",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "100041586",
            "url": "https://www.ncbi.nlm.nih.gov/gene/100041586",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "100041639",
            "url": "https://www.ncbi.nlm.nih.gov/gene/100041639",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "21647",
            "url": "https://www.ncbi.nlm.nih.gov/gene/21647",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "P11985",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:P11985*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR005334",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR005334",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR038586",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR038586",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:100041586",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:100041586",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "mmu:100041639",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:100041639",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "mmu:21647",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:21647",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "3781595",
            "url": "http://www.informatics.jax.org/marker/MGI:3781595",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "3809205",
            "url": "http://www.informatics.jax.org/marker/MGI:3809205",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "98642",
            "url": "http://www.informatics.jax.org/marker/MGI:98642",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "DFFFYVI",
            "url": "https://omabrowser.org/oma/group/DFFFYVI/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "EENAFHE",
            "url": "https://omabrowser.org/oma/group/EENAFHE/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "3132609at2759",
            "url": "http://www.orthodb.org/?query=3132609at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR21255",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21255",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR21255:SF27",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21255:SF27",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF03645",
            "url": "http://pfam.xfam.org/family/PF03645",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_P11985",
            "url": "http://purl.obolibrary.org/obo/PR_P11985",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-MMU-5620924",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5620924",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001116839",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116839",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0R4J284",
            "url": "https://www.uniprot.org/uniprot/A0A0R4J284",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0R4J284-1",
            "url": "https://www.uniprot.org/uniprot/A0A0R4J284-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A338P6U6",
            "url": "https://www.uniprot.org/uniprot/A0A338P6U6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A338P6U6-1",
            "url": "https://www.uniprot.org/uniprot/A0A338P6U6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A338P777",
            "url": "https://www.uniprot.org/uniprot/A0A338P777",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A338P777-1",
            "url": "https://www.uniprot.org/uniprot/A0A338P777-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P11985",
            "url": "https://www.uniprot.org/uniprot/P11985",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P11985-1",
            "url": "https://www.uniprot.org/uniprot/P11985-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P11985-2",
            "url": "https://www.uniprot.org/uniprot/P11985-2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MERRGRMAKTPTGQTHQSPVSKRERKPSMFEKESYAQILRERLRESFHDVQYVEPPFDDSIADVGKEWKSALAKLKFANSYRMEPLKKFQAHLVETKIQQILKDSLKDVKYDDKAPHLSLELADGILAAVKEFAYHRYKFIIQVLFIQKTGQAINIASRWIWDVAWDNWVEAKHETESYVVLALVFALYCE",
        "length": 191,
        "header": "sp|P11985-1|DYLT2_MOUSE Isoform 1 of Dynein light chain Tctex-type protein 2  OS=Mus musculus OX=10090 GN=Dynlt2 PE=1 SV=2 CANONICAL=P11985-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0R4J284-1",
            "url": "",
            "sequence": {
                "sequence": "MERRGRMAKTPTGQTHQSPVSKRERKPSMFEKESYAQILRERLRESFHDVQYVEPPFDDSIADVGKEWKSALAKLKFANSYRMEPLKKFQAHLVETKIQQILKDSLKDVKYDDKAPHLSLELADRILAAVKEFAYHRYKFIIQVLFIQKTGQAINIASRWIWDVAWDNWVEAKHETESYVVLALVFALYCE",
                "length": 191,
                "header": "tr|A0A0R4J284-1|DYLT2_MOUSE Computationally mapped isoform of Dynein light chain Tctex-type protein 2  OS=Mus musculus OX=10090 GN=Dynlt2 PE=1 SV=1 CANONICAL=P11985-1"
            },
            "locus": {
                "chromosome": "17",
                "start_pos": 15230291,
                "end_pos": 15216104,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000097400.5",
                        "url": "https://www.ensembl.org/id/ENSMUST00000097400.5"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000095012.5",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000095012.5"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A338P6U6-1",
            "url": "",
            "sequence": {
                "sequence": "MERRGRMAKTPTGQTHQSPVSKRERKPSMFEKESYAQILRERLRESFHDVQYVEPPFDDSIADVGKEWKSALAKLKFANSYRMEPLKKFQAHLVETKIQQILKVKESRWTFFQMLNCQQMDLGCGMGQLGRS",
                "length": 132,
                "header": "tr|A0A338P6U6-1|DYLT2_MOUSE Computationally mapped isoform of Dynein light chain Tctex-type protein 2  OS=Mus musculus OX=10090 GN=Dynlt2 PE=1 SV=1 CANONICAL=P11985-1"
            },
            "locus": {
                "chromosome": "17",
                "start_pos": 15198919,
                "end_pos": 15184568,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000232173.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000232173.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000156122.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000156122.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A338P777-1",
            "url": "",
            "sequence": {
                "sequence": "MERRGRMAKTPTGQTHQSPVSKRERKPSMFEKESVSGDRRPKTAFPPFR",
                "length": 49,
                "header": "tr|A0A338P777-1|DYLT2_MOUSE Computationally mapped isoform of Dynein light chain Tctex-type protein 2  OS=Mus musculus OX=10090 GN=Dynlt2 PE=1 SV=1 CANONICAL=P11985-1"
            },
            "locus": {
                "chromosome": "17",
                "start_pos": 15230291,
                "end_pos": 15230145,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000232299.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000232299.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000156126.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000156126.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "P11985-1",
            "url": "",
            "sequence": {
                "sequence": "MERRGRMAKTPTGQTHQSPVSKRERKPSMFEKESYAQILRERLRESFHDVQYVEPPFDDSIADVGKEWKSALAKLKFANSYRMEPLKKFQAHLVETKIQQILKDSLKDVKYDDKAPHLSLELADGILAAVKEFAYHRYKFIIQVLFIQKTGQAINIASRWIWDVAWDNWVEAKHETESYVVLALVFALYCE",
                "length": 191,
                "header": "sp|P11985-1|DYLT2_MOUSE Isoform 1 of Dynein light chain Tctex-type protein 2  OS=Mus musculus OX=10090 GN=Dynlt2 PE=1 SV=2 CANONICAL=P11985-1"
            },
            "locus": {
                "chromosome": "17",
                "start_pos": 15198919,
                "end_pos": 15184510,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000097399",
                        "url": "https://www.ensembl.org/id/ENSMUST00000097399"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000095011",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000095011"
                    }
                ]
            }
        },
        {
            "isoform_ac": "P11985-2",
            "url": "",
            "sequence": {
                "sequence": "MERRGRMAKTPTGQTHQSPVSKRERKPSMFEKESYAQILRERLRESFHDVQYVEPPFDDSIADVGKEWKSALAKLKFANSYRMEPLKKFQAHLVETKIQQILKIASRWIWDVAWDNWVEAKHETESYVVLALVFALYCE",
                "length": 139,
                "header": "sp|P11985-2|DYLT2_MOUSE Isoform 2 of Dynein light chain Tctex-type protein 2  OS=Mus musculus OX=10090 GN=Dynlt2 PE=1 SV=2 CANONICAL=P11985-1"
            },
            "locus": {
                "chromosome": "17",
                "start_pos": 15261659,
                "end_pos": 15247472,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000097398",
                        "url": "https://www.ensembl.org/id/ENSMUST00000097398"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000095010",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000095010"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "The Tctex1/Tctex2 class of dynein light chains. Dimerization, differential expression, and interaction with the LC8 protein family.",
            "journal": "J. Biol. Chem.",
            "date": "2001",
            "authors": "DiBella LM, Benashski SE, Tedford HW, Harrison A, Patel-King RS, King SM",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P11985",
                    "url": "https://www.uniprot.org/uniprot/P11985"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "11278908",
                    "url": "https://glygen.org/publication/PubMed/11278908"
                }
            ]
        },
        {
            "title": "The protein of a new gene, Tctex4, interacts with protein kinase CK2beta subunit and is highly expressed in mouse testis.",
            "journal": "Biochem. Biophys. Res. Commun.",
            "date": "2003",
            "authors": "Zhang F., Xu X., Shu H.-B., Bai X., Chan E.D.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P11985",
                    "url": "https://www.uniprot.org/uniprot/P11985"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12849985",
                    "url": "https://glygen.org/publication/PubMed/12849985"
                }
            ]
        },
        {
            "title": "Several testis-expressed genes in the mouse T-complex have expression differences between wild-type and t-mutant mice.",
            "journal": "Dev. Genet.",
            "date": "1991",
            "authors": "Abe K., Uehara H., Yeom Y.I., Ha H., Artzt K., Bennett D., Howard C.A.",
            "evidence": [
                {
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