{
    "uniprot_canonical_ac": "P07190-1",
    "uniprot_ac": "P07190",
    "uniprot_id": "MAL1_DROME",
    "mass": {
        "chemical_mass": 66386.0,
        "monoisotopic_mass": 66386.0
    },
    "refseq": {
        "ac": "NP_476627",
        "name": "maltase A1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476627"
    },
    "gene_names": [
        {
            "name": "Mal-A1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/P07190",
            "id": "P07190"
        },
        {
            "name": "CG8696; Dmel\\CG8696; Drome_A1; H; lvpH; LvpH; mal_A1; V",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476627",
            "id": "NP_476627"
        },
        {
            "name": "CG8696",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/P07190",
            "id": "P07190"
        },
        {
            "name": "LvpH",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/P07190",
            "id": "P07190"
        },
        {
            "name": "Mal-A1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476627",
            "id": "NP_476627"
        }
    ],
    "protein_names": [
        {
            "name": "Maltase A1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "P07190"
        },
        {
            "name": "3.2.1.20",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P07190"
        },
        {
            "name": "CG8696-PA; Mal-A1-PA; maltase H precursor; larval visceral protein H; gene V; hdl cuticle gene cluster",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476627",
            "id": "NP_476627"
        },
        {
            "name": "Larval visceral protein H",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "P07190"
        },
        {
            "name": "maltase A1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476627",
            "id": "NP_476627"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:9266",
            "recommended_name": {
                "id": "DOID:9266",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:9266",
                "name": "cystinuria",
                "description": "An amino acid metabolic disorder that involves the formation of cystine stones in the kidneys, ureter, and bladder."
            },
            "synonyms": [
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "cystinuria",
                    "description": "Cystinuria is a renal tubular amino acid transport disorder characterized by recurrent formation of kidneys cystine stones."
                },
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "cystinuria",
                    "description": ""
                },
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "cystinuria (disease)",
                    "description": ""
                },
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "cystinuria-lysinuria syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "CSNU",
                    "description": ""
                },
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "cystinuria, type A/B",
                    "description": ""
                },
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "cystinuria, type B",
                    "description": ""
                },
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "cystinuria, type I",
                    "description": ""
                },
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "cystinuria, type I, formerly",
                    "description": ""
                },
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "cystinuria, type II",
                    "description": ""
                },
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "cystinuria, type II, formerly",
                    "description": ""
                },
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "cystinuria, type III",
                    "description": ""
                },
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "cystinuria, type III, formerly",
                    "description": ""
                },
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "cystinuria, type a",
                    "description": ""
                },
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "cystinuria, type non-I",
                    "description": ""
                },
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "cystinuria, type non-I, formerly",
                    "description": ""
                },
                {
                    "id": "MONDO:0009067",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009067",
                    "name": "cystinuria-lysinuria",
                    "description": ""
                },
                {
                    "id": "MIM:220100",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/220100",
                    "name": "Cystinuria",
                    "description": "Cystinuria"
                }
            ],
            "evidence": [
                {
                    "id": "9266",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:9266"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Drosophila melanogaster",
            "taxid": 7227,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P07190",
                    "url": "https://www.uniprot.org/uniprot/P07190"
                }
            ],
            "common_name": "Fruit fly"
        }
    ],
    "gene": [
        {
            "name": "Mal-A1",
            "url": "https://www.uniprot.org/uniprot/P07190",
            "locus": {
                "chromosome": "2R",
                "start_pos": 8449664,
                "end_pos": 8451904,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "FBgn0002570",
                        "url": "https://www.ensembl.org/id/FBgn0002570"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "FBgn0002570",
            "url": "https://bgee.org/?page=gene&gene_id=FBgn0002570",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "GH13",
            "url": "http://www.cazy.org/GH13.html",
            "database": "CAZy",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd11328",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11328",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "FBgn0002570",
            "url": "https://flybase.org/reports/FBgn0002570",
            "database": "FlyBase",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "35824",
            "url": "https://www.ncbi.nlm.nih.gov/gene/35824",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "P07190",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:P07190*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR006047",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006047",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013780",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013780",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR017853",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR045857",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR045857",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dme:Dmel_CG8696",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG8696",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "HATRFAN",
            "url": "https://omabrowser.org/oma/group/HATRFAN/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "3680211at2759",
            "url": "http://www.orthodb.org/?query=3680211at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR10357",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10357",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR10357:SF179",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10357:SF179",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00128",
            "url": "http://pfam.xfam.org/family/PF00128",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_P07190",
            "url": "http://purl.obolibrary.org/obo/PR_P07190",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_476627",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_476627",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P07190",
            "url": "https://www.uniprot.org/uniprot/P07190",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "P07190-1",
            "url": "https://www.uniprot.org/uniprot/P07190-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MRPQSAACLLLAIVGFVGATEWWESGNYYQIYPRSFRDSDGDGIGDLNGVTEKLQYLKDIGFTGTWLSPIFKSPMVDFGYDISDFYQIHPEYGTMEDFERMIAKAKEVGIKIILDFVPNHSSTENEWFTKSVDSDPVYKDFYIWHDGKINNETGEREPPSNWNSEFRYSAWEWNEVRQQYYLHQFAIQQADLNYRNPAVVNEMKNVIRFWLGKGVSGFRIDAVPYLFEVDLDRYNQYPDEPLTNDSVNCPDPDDHCYTQHIYTQDMPETIDMVYQWRELVDEFHVENGGDKRLLMTEAYTSFENIMTYYGNGVRNGSHIPFNFDFLTSINNASKAGEYVEHIKKWMDAMPEGVYANWVLGNHDNKRVASRFGVQRTDLINILLQTLPGHAVTYNGEELGMTDVWISWEDTVDPNACNSDPDNYYARSRDPARSPYQWDASSKAGFTSADHTWLPVADDYKTNNALQQLRAPRSHLQIFKKLVRVRKEPSFRQGELNIQAIDDDVIIYSRQKTGSDLYVIVLNLGSTSKTLDLTKYYELGTQAEVITTSLSSQYIDGDVIKSTEFVANPYVGTVLVAV",
        "length": 577,
        "header": "sp|P07190-1|MAL1_DROME Isoform 1 of Maltase A1  OS=Drosophila melanogaster OX=7227 GN=Mal-A1 PE=2 SV=2 CANONICAL=P07190-1"
    },
    "isoforms": [
        {
            "isoform_ac": "P07190-1",
            "url": "",
            "sequence": {
                "sequence": "MRPQSAACLLLAIVGFVGATEWWESGNYYQIYPRSFRDSDGDGIGDLNGVTEKLQYLKDIGFTGTWLSPIFKSPMVDFGYDISDFYQIHPEYGTMEDFERMIAKAKEVGIKIILDFVPNHSSTENEWFTKSVDSDPVYKDFYIWHDGKINNETGEREPPSNWNSEFRYSAWEWNEVRQQYYLHQFAIQQADLNYRNPAVVNEMKNVIRFWLGKGVSGFRIDAVPYLFEVDLDRYNQYPDEPLTNDSVNCPDPDDHCYTQHIYTQDMPETIDMVYQWRELVDEFHVENGGDKRLLMTEAYTSFENIMTYYGNGVRNGSHIPFNFDFLTSINNASKAGEYVEHIKKWMDAMPEGVYANWVLGNHDNKRVASRFGVQRTDLINILLQTLPGHAVTYNGEELGMTDVWISWEDTVDPNACNSDPDNYYARSRDPARSPYQWDASSKAGFTSADHTWLPVADDYKTNNALQQLRAPRSHLQIFKKLVRVRKEPSFRQGELNIQAIDDDVIIYSRQKTGSDLYVIVLNLGSTSKTLDLTKYYELGTQAEVITTSLSSQYIDGDVIKSTEFVANPYVGTVLVAV",
                "length": 577,
                "header": "sp|P07190-1|MAL1_DROME Isoform 1 of Maltase A1  OS=Drosophila melanogaster OX=7227 GN=Mal-A1 PE=2 SV=2 CANONICAL=P07190-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 8451884,
                "end_pos": 8449739,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0088759",
                        "url": "https://www.ensembl.org/id/FBtr0088759"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0087838",
                        "url": "https://www.ensembl.org/id/FBpp0087838"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 119,
            "start_aa": "Asn",
            "end_pos": 119,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn119",
            "evidence": [
                {
                    "id": "P07190",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P07190#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 151,
            "start_aa": "Asn",
            "end_pos": 151,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn151",
            "evidence": [
                {
                    "id": "P07190",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P07190#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 244,
            "start_aa": "Asn",
            "end_pos": 244,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn244",
            "evidence": [
                {
                    "id": "P07190",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P07190#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 315,
            "start_aa": "Asn",
            "end_pos": 315,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn315",
            "evidence": [
                {
                    "id": "P07190",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P07190#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 331,
            "start_aa": "Asn",
            "end_pos": 331,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn331",
            "evidence": [
                {
                    "id": "P07190",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/P07190#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "enzyme",
        "glycohydrolase-activity",
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [
        {
            "title": "The genome sequence of Drosophila melanogaster.",
            "journal": "Science",
            "date": "2000",
            "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P07190",
                    "url": "https://www.uniprot.org/uniprot/P07190"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "10731132",
                    "url": "https://glygen.org/publication/PubMed/10731132"
                }
            ]
        },
        {
            "title": "A Drosophila full-length cDNA resource.",
            "journal": "Genome Biol.",
            "date": "2002",
            "authors": "Stapleton M, Carlson J, Brokstein P, Yu C, Champe M, George R, Guarin H, Kronmiller B, Pacleb J, Park S, Wan K, Rubin GM, Celniker SE",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "P07190",
                    "url": "https://www.uniprot.org/uniprot/P07190"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12537569",
                    "url": "https://glygen.org/publication/PubMed/12537569"
                }
            ]
        },
        {
            "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.",
            "journal": "Genome Biol.",
            "date": "2002",
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