{ "uniprot_canonical_ac": "P03875-1", "uniprot_ac": "P03875", "uniprot_id": "AI1M_YEAST", "mass": { "chemical_mass": 96079.0, "monoisotopic_mass": 96079.0 }, "refseq": { "ac": "NP_009310", "name": "intron-encoded reverse transcriptase aI1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009310" }, "gene_names": [ { "name": "AI1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/P03875", "id": "P03875" }, { "name": "AI1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009310", "id": "NP_009310" } ], "protein_names": [ { "name": "Putative COX1/OXI3 intron 1 protein", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "P03875" }, { "name": "intron-encoded reverse transcriptase aI1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009310", "id": "NP_009310" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "P03875", "url": "https://www.uniprot.org/uniprot/P03875" } ], "common_name": "Yeast" } ], "gene": [ { "name": "AI1", "url": "https://www.uniprot.org/uniprot/P03875", "locus": {} } ], "crossref": [ { "id": "cd00085", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00085", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01651", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01651", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "854593", "url": "https://www.ncbi.nlm.nih.gov/gene/854593", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "P03875", "url": "https://www.ebi.ac.uk/intact/interactors/id:P03875*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036927", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036927", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "sce:Q0050", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:Q0050", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VFIRITI", "url": "https://omabrowser.org/oma/group/VFIRITI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "3640877at2759", "url": "http://www.orthodb.org/?query=3640877at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33642", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33642", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33642:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33642:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00078", "url": "http://pfam.xfam.org/family/PF00078", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF01348", "url": "http://pfam.xfam.org/family/PF01348", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_P03875", "url": "http://purl.obolibrary.org/obo/PR_P03875", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_009310", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009310", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "S000007261", "url": "https://www.yeastgenome.org/locus/S000007261", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "P03875", "url": "https://www.uniprot.org/uniprot/P03875", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P03875-1", "url": "https://www.uniprot.org/uniprot/P03875-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNGAPTSAYISLMRTALVLWIINRYLKHMTNSVGANFTGTMACHKTPMISVGGVKCYMVRLTNFLQVFIRITISSYHLDMVKQVWLFYVEVIRLWFIVLDSTGSVKKMKDTNNTKGNTKSEGSTERGNSGVDRGMVVPNTQMKMRFLNQVRYYSVNNNLKMGKDTNIELSKDTSTSDLLEFEKLVMDNMNEENMNNNLLSIMKNVDMLMLAYNRIKSKPGNMTPGTTLETLDGMNMMYLNKLSNELGTGKFKFKPMRMVNIPKPKGGMRPLSVGNPRDKIVQEVMRMILDTIFDKKMSTHSHGFRKNMSCQTAIWEVRNMFGGSNWFIEVDLKKCFDTISHDLIIKELKRYISDKGFIDLVYKLLRAGYIDEKGTYHKPMLGLPQGSLISPILCNIVMTLVDNWLEDYINLYNKGKVKKQHPTYKKLSRMIAKAKMFSTRLKLHKERAKGPTFIYNDPNFKRMKYVRYADDILIGVLGSKNDCKMIKRDLNNFLNSLGLTMNEEKTLITCATETPARFLGYNISITPLKRMPTVTKTIRGKTIRSRNTTRPIINAPIRDIINKLATNGYCKHNKNGRMGVPTRVGRWTYEEPRTIINNYKALGRGILNYYKLATNYKRLRERIYYVLYYSCVLTLASKYRLKTMSKTIKKFGYNLNIIENDKLIANFPRNTFDNIKKIENHGMFMYMSEAKVTDPFEYIDSIKYMLPTAKANFNKPCSICNSTIDVEMHHVKQLHRGMLKATKDYITGRMITMNRKQIPLCKQCHIKTHKNKFKNMGPGM", "length": 834, "header": "sp|P03875-1|AI1M_YEAST Isoform 1 of Putative COX1/OXI3 intron 1 protein OS=Saccharomyces cerevisiae S288C OX=559292 GN=AI1 PE=4 SV=2 CANONICAL=P03875-1" }, "isoforms": [ { "isoform_ac": "P03875-1", "url": "", "sequence": { "sequence": "MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNGAPTSAYISLMRTALVLWIINRYLKHMTNSVGANFTGTMACHKTPMISVGGVKCYMVRLTNFLQVFIRITISSYHLDMVKQVWLFYVEVIRLWFIVLDSTGSVKKMKDTNNTKGNTKSEGSTERGNSGVDRGMVVPNTQMKMRFLNQVRYYSVNNNLKMGKDTNIELSKDTSTSDLLEFEKLVMDNMNEENMNNNLLSIMKNVDMLMLAYNRIKSKPGNMTPGTTLETLDGMNMMYLNKLSNELGTGKFKFKPMRMVNIPKPKGGMRPLSVGNPRDKIVQEVMRMILDTIFDKKMSTHSHGFRKNMSCQTAIWEVRNMFGGSNWFIEVDLKKCFDTISHDLIIKELKRYISDKGFIDLVYKLLRAGYIDEKGTYHKPMLGLPQGSLISPILCNIVMTLVDNWLEDYINLYNKGKVKKQHPTYKKLSRMIAKAKMFSTRLKLHKERAKGPTFIYNDPNFKRMKYVRYADDILIGVLGSKNDCKMIKRDLNNFLNSLGLTMNEEKTLITCATETPARFLGYNISITPLKRMPTVTKTIRGKTIRSRNTTRPIINAPIRDIINKLATNGYCKHNKNGRMGVPTRVGRWTYEEPRTIINNYKALGRGILNYYKLATNYKRLRERIYYVLYYSCVLTLASKYRLKTMSKTIKKFGYNLNIIENDKLIANFPRNTFDNIKKIENHGMFMYMSEAKVTDPFEYIDSIKYMLPTAKANFNKPCSICNSTIDVEMHHVKQLHRGMLKATKDYITGRMITMNRKQIPLCKQCHIKTHKNKFKNMGPGM", "length": 834, "header": "sp|P03875-1|AI1M_YEAST Isoform 1 of Putative COX1/OXI3 intron 1 protein OS=Saccharomyces cerevisiae S288C OX=559292 GN=AI1 PE=4 SV=2 CANONICAL=P03875-1" }, "locus": { "chromosome": "Mitochondrion", "start_pos": 16319, "end_pos": 13818, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "Q0050_mRNA", "url": "https://www.ensembl.org/id/Q0050_mRNA" }, { "database": "Ensembl Peptide", "id": "Q0050", "url": "https://www.ensembl.org/id/Q0050" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.", "journal": "G3 (Bethesda)", "date": "2014", "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael", "evidence": [ { "database": "UniProtKB", "id": "P03875", "url": "https://www.uniprot.org/uniprot/P03875" } ], "reference": [ { "type": "PubMed", "id": "24374639", "url": "https://glygen.org/publication/PubMed/24374639" } ] }, { "title": "The primary structure of the mitochondrial genome of Saccharomyces cerevisiae -- a review.", "journal": "Gene", "date": "1986", "authors": "Bernardi G., de Zamaroczy M.", "evidence": [ { "database": "UniProtKB", "id": "P03875", "url": "https://www.uniprot.org/uniprot/P03875" } ], "reference": [ { "type": "PubMed", "id": "3549452", "url": "https://glygen.org/publication/PubMed/3549452" } ] }, { "title": "Assembly of the mitochondrial membrane system. Structure and nucleotide sequence of the gene coding for subunit 1 of yeast cytochrome oxidase.", "journal": "J. Biol. Chem.", "date": "1980", "authors": "Tzagoloff A., Macino G., Bonitz S.G., Coruzzi G., Thalenfeld B.E.", "evidence": [ { "database": "UniProtKB", "id": "P03875", "url": "https://www.uniprot.org/uniprot/P03875" } ], "reference": [ { "type": "PubMed", "id": "6254986", "url": "https://glygen.org/publication/PubMed/6254986" } ] }, { "title": "The complete sequence of the mitochondrial genome of Saccharomyces cerevisiae.", "journal": "FEBS Lett.", "date": "1998", "authors": "Foury F., Purnelle B., Lecrenier N., Roganti T.", "evidence": [ { "database": "UniProtKB", "id": "P03875", "url": "https://www.uniprot.org/uniprot/P03875" } ], "reference": [ { "type": "PubMed", "id": "9872396", "url": "https://glygen.org/publication/PubMed/9872396" } ] } ], "pathway": [ { "id": "sce:Q0050", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+sce:Q0050", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "RNA-templated DNA biosynthetic process", "id": "GO:0006278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006278", "evidence": [ { "database": "UniProtKB", "id": "P03875", "url": "https://www.uniprot.org/uniprot/P03875" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "P03875", "url": "https://www.uniprot.org/uniprot/P03875" } ], "pmid": "" }, { "name": "mitochondrial mRNA processing", "id": "GO:0090615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090615", "evidence": [ { "database": "UniProtKB", "id": "P03875", "url": "https://www.uniprot.org/uniprot/P03875" } ], "pmid": "" }, { "name": "homing of group II introns", "id": "GO:0006315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006315", "evidence": [ { "database": "UniProtKB", "id": "P03875", "url": "https://www.uniprot.org/uniprot/P03875" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "P03875", "url": "https://www.uniprot.org/uniprot/P03875" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P03875", "url": "https://www.uniprot.org/uniprot/P03875" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 775, "end_pos": 777, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }