{
    "uniprot_canonical_ac": "O46102-1",
    "uniprot_ac": "O46102",
    "uniprot_id": "PAPD1_DROME",
    "mass": {
        "chemical_mass": 68546.0,
        "monoisotopic_mass": 68546.0
    },
    "refseq": {
        "ac": "NP_996325",
        "name": "mitochondrial poly(A) polymerase, isoform B",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996325"
    },
    "gene_names": [
        {
            "name": "MTPAP",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/O46102",
            "id": "O46102"
        },
        {
            "name": "CG11418; Dmel\\CG11418; dmmtpap; DmMTPAP; DmNP_569904; EG:8D8.8; SD27341p; TUTase1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259129",
            "id": "NP_001259129"
        },
        {
            "name": "CG11418",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/O46102",
            "id": "O46102"
        },
        {
            "name": "DmMTPAP",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/O46102",
            "id": "O46102"
        },
        {
            "name": "DmNP_569904",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/O46102",
            "id": "O46102"
        },
        {
            "name": "Dmel\\CG11418",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/O46102",
            "id": "O46102"
        },
        {
            "name": "Dmel_CG11418",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/O46102",
            "id": "O46102"
        },
        {
            "name": "EG:8D8.8",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/O46102",
            "id": "O46102"
        },
        {
            "name": "MTPAP",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259129",
            "id": "NP_001259129"
        },
        {
            "name": "SD27341p",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/O46102",
            "id": "O46102"
        },
        {
            "name": "TUTase1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/O46102",
            "id": "O46102"
        },
        {
            "name": "dmmtpap",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/O46102",
            "id": "O46102"
        }
    ],
    "protein_names": [
        {
            "name": "Poly(A) RNA polymerase, mitochondrial",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "O46102"
        },
        {
            "name": "2.7.7.19",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "O46102"
        },
        {
            "name": "CG11418-PB; MTPAP-PB; 3' terminal uridylyl transferase 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996325",
            "id": "NP_996325"
        },
        {
            "name": "CG11418-PC; MTPAP-PC; 3' terminal uridylyl transferase 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259129",
            "id": "NP_001259129"
        },
        {
            "name": "DmMTPAP",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "O46102"
        },
        {
            "name": "mitochondrial poly(A) polymerase, isoform B",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996325",
            "id": "NP_996325"
        },
        {
            "name": "mitochondrial poly(A) polymerase, isoform C",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259129",
            "id": "NP_001259129"
        }
    ],
    "function": [
        {
            "annotation": "Polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. This is not required for transcript stability or translation but may maintain mRNA integrity by protecting 3' termini from degradation.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O46102",
                    "url": "https://www.uniprot.org/uniprot/O46102#function"
                },
                {
                    "database": "PubMed",
                    "id": "27176048",
                    "url": "https://glygen.org/publication/PubMed/27176048"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0050943",
            "recommended_name": {
                "id": "DOID:0050943",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050943",
                "name": "spastic ataxia 4",
                "description": "A spastic ataxia that is characterized by cerebellar ataxia, spasticity, dysarthria and optic atrophy, has_material_basis_in homozygous mutation in the MTPAP gene on chromosome 10p11."
            },
            "synonyms": [
                {
                    "id": "MONDO:0013354",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013354",
                    "name": "spastic ataxia 4",
                    "description": "Any autosomal recessive spastic ataxia in which the cause of the disease is a mutation in the MTPAP gene."
                },
                {
                    "id": "MONDO:0013354",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013354",
                    "name": "MTPAP autosomal recessive spastic ataxia",
                    "description": ""
                },
                {
                    "id": "MONDO:0013354",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013354",
                    "name": "SPAX4",
                    "description": ""
                },
                {
                    "id": "MONDO:0013354",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013354",
                    "name": "autosomal recessive spastic ataxia caused by mutation in MTPAP",
                    "description": ""
                },
                {
                    "id": "MONDO:0013354",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013354",
                    "name": "autosomal recessive spastic ataxia type 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0013354",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013354",
                    "name": "spastic ataxia type 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0013354",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013354",
                    "name": "autosomal recessive spastic ataxia - optic atrophy - dysarthria",
                    "description": ""
                },
                {
                    "id": "MONDO:0013354",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013354",
                    "name": "autosomal recessive spastic ataxia 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0013354",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013354",
                    "name": "autosomal recessive spastic ataxia-optic atrophy-dysarthria syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0013354",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013354",
                    "name": "spastic ataxia 4, autosomal recessive",
                    "description": ""
                },
                {
                    "id": "MIM:613672",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/613672",
                    "name": "Spastic ataxia 4, autosomal recessive",
                    "description": "Spastic ataxia 4, autosomal recessive"
                }
            ],
            "evidence": [
                {
                    "id": "0050943",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050943"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Drosophila melanogaster",
            "taxid": 7227,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O46102",
                    "url": "https://www.uniprot.org/uniprot/O46102"
                }
            ],
            "common_name": "Fruit fly"
        }
    ],
    "gene": [
        {
            "name": "MTPAP",
            "url": "https://www.uniprot.org/uniprot/O46102",
            "locus": {
                "chromosome": "X",
                "start_pos": 1344872,
                "end_pos": 1349357,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "FBgn0024360",
                        "url": "https://www.ensembl.org/id/FBgn0024360"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "FBgn0024360",
            "url": "https://bgee.org/?page=gene&gene_id=FBgn0024360",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd05402",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05402",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "FBgn0024360",
            "url": "https://flybase.org/reports/FBgn0024360",
            "database": "FlyBase",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "31081",
            "url": "https://www.ncbi.nlm.nih.gov/gene/31081",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "O46102",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:O46102*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR002058",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002058",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR043519",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR043519",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dme:Dmel_CG11418",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG11418",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "RTVLIKC",
            "url": "https://omabrowser.org/oma/group/RTVLIKC/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "170176at2759",
            "url": "http://www.orthodb.org/?query=170176at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12271",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12271",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12271:SF33",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12271:SF33",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF03828",
            "url": "http://pfam.xfam.org/family/PF03828",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_O46102",
            "url": "http://purl.obolibrary.org/obo/PR_O46102",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_001259129",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259129",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "11332",
            "url": "https://www.rhea-db.org/rhea/11332",
            "database": "Rhea",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "O46102",
            "url": "https://www.uniprot.org/uniprot/O46102",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "O46102-1",
            "url": "https://www.uniprot.org/uniprot/O46102-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q7KW16",
            "url": "https://www.uniprot.org/uniprot/Q7KW16",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q7KW16-1",
            "url": "https://www.uniprot.org/uniprot/Q7KW16-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MNSLVRRSAQQLSLWRTYCIKHNASEAASPGRNAGRPNYEEFIGRHQRQAQCSIVVQVSSEKSYEELYNYCSSFGSIMGAHHYCVRQDETLHYILLEYATSDEAAAAIGAGVTNGELSGVPVRSPFLWFRAAGGGRRSPKLVANTAPALLSLDGTRQVDQRHLLGLLRGAADIEEQVQQLYEHTRLNELGIRMRFLAALQVQQAIAGMFPAAQAQPFGSSVNGFGRMGCDLDLILRFDSDMGAKIPLEAAVPSRLVYHTKENLSNGRSQTQRHMECFGDMLHLFLPGVCHVRRILQARVPIIKYHHEHLDLEVDLSMSNLTGFYMSELLYMFGEMDPRVRPLTFTIRRWAQTCGLTNPSPGRWISNFSLTCLVMFFLQQLRQPILPTIGALAKAAEPGDSRVTEDGINCTFTRNVDRLGFRSRNQSSLSELLLQFFEFYSQFDFHNRAISLNEGKPLSKPDHSAMYIVNPLEQLLNVSKNVSLEECERLRIEVRNAAWVLESEVENASVPEGDGQELSCGLLNLFKHPEKAVIRPNMFFKPRMVEVSDLFEQKEAGATSSSTPPTPAITYKSASVRQQVQSIKAATRSELKQLRGSGSSVPTSSPNNRRRSR",
        "length": 612,
        "header": "sp|O46102-1|PAPD1_DROME Isoform 1 of Poly(A) RNA polymerase, mitochondrial  OS=Drosophila melanogaster OX=7227 GN=MTPAP PE=2 SV=2 CANONICAL=O46102-1"
    },
    "isoforms": [
        {
            "isoform_ac": "O46102-1",
            "url": "",
            "sequence": {
                "sequence": "MNSLVRRSAQQLSLWRTYCIKHNASEAASPGRNAGRPNYEEFIGRHQRQAQCSIVVQVSSEKSYEELYNYCSSFGSIMGAHHYCVRQDETLHYILLEYATSDEAAAAIGAGVTNGELSGVPVRSPFLWFRAAGGGRRSPKLVANTAPALLSLDGTRQVDQRHLLGLLRGAADIEEQVQQLYEHTRLNELGIRMRFLAALQVQQAIAGMFPAAQAQPFGSSVNGFGRMGCDLDLILRFDSDMGAKIPLEAAVPSRLVYHTKENLSNGRSQTQRHMECFGDMLHLFLPGVCHVRRILQARVPIIKYHHEHLDLEVDLSMSNLTGFYMSELLYMFGEMDPRVRPLTFTIRRWAQTCGLTNPSPGRWISNFSLTCLVMFFLQQLRQPILPTIGALAKAAEPGDSRVTEDGINCTFTRNVDRLGFRSRNQSSLSELLLQFFEFYSQFDFHNRAISLNEGKPLSKPDHSAMYIVNPLEQLLNVSKNVSLEECERLRIEVRNAAWVLESEVENASVPEGDGQELSCGLLNLFKHPEKAVIRPNMFFKPRMVEVSDLFEQKEAGATSSSTPPTPAITYKSASVRQQVQSIKAATRSELKQLRGSGSSVPTSSPNNRRRSR",
                "length": 612,
                "header": "sp|O46102-1|PAPD1_DROME Isoform 1 of Poly(A) RNA polymerase, mitochondrial  OS=Drosophila melanogaster OX=7227 GN=MTPAP PE=2 SV=2 CANONICAL=O46102-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 1349246,
                "end_pos": 1345244,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0332288",
                        "url": "https://www.ensembl.org/id/FBtr0332288"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0304567",
                        "url": "https://www.ensembl.org/id/FBpp0304567"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q7KW16-1",
            "url": "",
            "sequence": {
                "sequence": "MSELLYMFGEMDPRVRPLTFTIRRWAQTCGLTNPSPGRWISNFSLTCLVMFFLQQLRQPILPTIGALAKAAEPGDSRVTEDGINCTFTRNVDRLGFRSRNQSSLSELLLQFFEFYSQFDFHNRAISLNEGKPLSKPDHSAMYIVNPLEQLLNVSKNVSLEECERLRIEVRNAAWVLESEVENASVPEGDGQELSCGLLNLFKHPEKAVIRPNMFFKPRMVEVSDLFEQKEAGATSSSTPPTPAITYKSASVRQQVQSIKAATRSELKQLRGSGSSVPTSSPNNRRRSR",
                "length": 288,
                "header": "tr|Q7KW16-1|Q7KW16_DROME Computationally mapped isoform of Mitochondrial poly(A) polymerase, isoform B  OS=Drosophila melanogaster OX=7227 GN=MTPAP PE=4 SV=1 CANONICAL=O46102-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 1346107,
                "end_pos": 1345244,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0070237",
                        "url": "https://www.ensembl.org/id/FBtr0070237"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0089095",
                        "url": "https://www.ensembl.org/id/FBpp0089095"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "enzyme"
    ],
    "publication": [
        {
            "title": "The genome sequence of Drosophila melanogaster.",
            "journal": "Science",
            "date": "2000",
            "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O46102",
                    "url": "https://www.uniprot.org/uniprot/O46102"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q7KW16",
                    "url": "https://www.uniprot.org/uniprot/Q7KW16"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "10731132",
                    "url": "https://glygen.org/publication/PubMed/10731132"
                }
            ]
        },
        {
            "title": "From sequence to chromosome: the tip of the X chromosome of D. melanogaster.",
            "journal": "Science",
            "date": "2000",
            "authors": "Galibert F., Barrell B.G., Schaefer U., Harris D., Werner M., Glover D.M., Cox S., Dreano S., Mottier S., Jaeckle H., Vidal S., Ferraz C., Brun C., Gatt M.K., Dowe G., Minana B., Modolell J., Campbell L.A., Ashburner M., Kafatos F.C., Valenti P., Louis C., Saunders R.D.C., Benos P.V., Bolshakov S., Borkova D., Cadieu E., Murphy L., Salles C., Siden-Kiamos I., de Pablos B., Beinert N., Bucheton A., Callister D.M., Darlamitsou A., Demailles J., Gloux S., Henderson N.S., Lelaure V., Madueno E., McMillan P.J., Mourkioti F., Papagiannakis G., Peter A., Schoettler P., Spanos L., Tait E.A.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O46102",
                    "url": "https://www.uniprot.org/uniprot/O46102"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "10731137",
                    "url": "https://glygen.org/publication/PubMed/10731137"
                }
            ]
        },
        {
            "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.",
            "journal": "Genome Biol.",
            "date": "2002",
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                        {
                            "id": "O46102",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/O46102"
                        }
                    ]
                }
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        {
            "uniprot_ac": "P29468",
            "gene_name": "PAP1",
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                {
                    "ec_number": "2.7.7.19",
                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
                    "evidence": [
                        {
                            "id": "P29468",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29468"
                        }
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                {
                    "ec_number": "2.7.7.19",
                    "activity": "",
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                        {
                            "id": "P29468",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P29468"
                        }
                    ]
                }
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            "uniprot_ac": "P48561",
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                {
                    "ec_number": "2.7.7.19",
                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
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                            "id": "P48561",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P48561"
                        }
                    ]
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                {
                    "ec_number": "2.7.7.19",
                    "activity": "",
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                        {
                            "id": "P48561",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P48561"
                        }
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                }
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        {
            "uniprot_ac": "P51003",
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                {
                    "ec_number": "2.7.7.19",
                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
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                        {
                            "id": "P51003",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P51003"
                        }
                    ]
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                {
                    "ec_number": "2.7.7.19",
                    "activity": "",
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                        {
                            "id": "P51003",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P51003"
                        }
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                }
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                {
                    "ec_number": "2.7.7.19",
                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
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                        {
                            "id": "P53632",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P53632"
                        }
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                {
                    "ec_number": "2.7.7.19",
                    "activity": "",
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                        {
                            "id": "P53632",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P53632"
                        }
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                }
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                {
                    "ec_number": "2.7.7.52",
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                            "id": "Q3MHT4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q3MHT4"
                        }
                    ]
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                {
                    "ec_number": "2.7.7.19",
                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
                    "evidence": [
                        {
                            "id": "Q3MHT4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q3MHT4"
                        }
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                {
                    "ec_number": "2.7.7.19",
                    "activity": "",
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                        {
                            "id": "Q3MHT4",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q3MHT4"
                        }
                    ]
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                {
                    "ec_number": "2.7.7.19",
                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
                    "evidence": [
                        {
                            "id": "Q54J73",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54J73"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.7.19",
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                        {
                            "id": "Q54J73",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q54J73"
                        }
                    ]
                }
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                {
                    "ec_number": "2.7.7.19",
                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
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                        {
                            "id": "Q5SSF7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5SSF7"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.7.19",
                    "activity": "",
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                        {
                            "id": "Q5SSF7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5SSF7"
                        }
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                }
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        {
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                {
                    "ec_number": "2.7.7.19",
                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
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                            "id": "Q5U315",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U315"
                        }
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                },
                {
                    "ec_number": "2.7.7.19",
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                        {
                            "id": "Q5U315",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5U315"
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                }
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                    "ec_number": "2.7.7.19",
                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
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                            "id": "Q5VWP2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5VWP2"
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                    ]
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                {
                    "ec_number": "2.7.7.19",
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                            "id": "Q5VWP2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5VWP2"
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                    "ec_number": "2.7.7.-",
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                            "id": "Q5XG87",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5XG87"
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                {
                    "ec_number": "2.7.7.19",
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                            "id": "Q5XG87",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5XG87"
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                    "ec_number": "2.7.7.19",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5XIV0"
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                {
                    "ec_number": "2.7.7.19",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5XIV0"
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                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
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                            "url": "https://www.uniprot.org/uniprot/Q61183"
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                {
                    "ec_number": "2.7.7.19",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q61183"
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                            "url": "https://www.uniprot.org/uniprot/Q68ED3"
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                            "id": "Q68ED3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q68ED3"
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                            "url": "https://www.uniprot.org/uniprot/Q6PB75"
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                {
                    "ec_number": "2.7.7.19",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6PB75"
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                    "ec_number": "2.7.7.19",
                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6PCL9"
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                {
                    "ec_number": "2.7.7.19",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6PCL9"
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                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6PIY7"
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                {
                    "ec_number": "2.7.7.19",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q6PIY7"
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                    "ec_number": "2.7.7.19",
                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q7KVS9"
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                    ]
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                {
                    "ec_number": "2.7.7.19",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q7KVS9"
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        {
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                {
                    "ec_number": "2.7.7.19",
                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
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                {
                    "ec_number": "2.7.7.19",
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                            "url": "https://www.uniprot.org/uniprot/Q8C152"
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        {
            "uniprot_ac": "Q8NDF8",
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                    "ec_number": "2.7.7.-",
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                            "url": "https://www.uniprot.org/uniprot/Q8NDF8"
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                {
                    "ec_number": "2.7.7.19",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8NDF8"
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                    "ec_number": "2.7.7.19",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8NEK8"
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                {
                    "ec_number": "2.7.7.19",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8NEK8"
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                            "url": "https://www.uniprot.org/uniprot/Q8R3F9"
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                {
                    "ec_number": "2.7.7.19",
                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
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                {
                    "ec_number": "2.7.7.19",
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                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
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                            "url": "https://www.uniprot.org/uniprot/Q91YI6"
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                    "ec_number": "2.7.7.19",
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                            "url": "https://www.uniprot.org/uniprot/Q91YI6"
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                            "url": "https://www.uniprot.org/uniprot/Q96A09"
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                    "ec_number": "2.7.7.19",
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                            "url": "https://www.uniprot.org/uniprot/Q96A09"
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        {
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                    "ec_number": "2.7.7.19",
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                            "url": "https://www.uniprot.org/uniprot/Q96IP4"
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        {
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                    "ec_number": "2.7.7.19",
                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
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                {
                    "ec_number": "2.7.7.19",
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                            "url": "https://www.uniprot.org/uniprot/Q9BWT3"
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                    ]
                }
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        },
        {
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                    "ec_number": "2.7.7.19",
                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
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                            "url": "https://www.uniprot.org/uniprot/Q9D0D3"
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                    ]
                },
                {
                    "ec_number": "2.7.7.19",
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                            "url": "https://www.uniprot.org/uniprot/Q9D0D3"
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                    ]
                }
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        },
        {
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                    "activity": "RNA(n) + UTP = diphosphate + RNA(n)-3'-uridine ribonucleotide.",
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                    ]
                },
                {
                    "ec_number": "2.7.7.19",
                    "activity": "ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide.",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q9H6E5"
                        }
                    ]
                },
                {
                    "ec_number": "2.7.7.52",
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                            "url": "https://www.uniprot.org/uniprot/Q9H6E5"
                        }
                    ]
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                {
                    "ec_number": "2.7.7.19",
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