{
    "uniprot_canonical_ac": "O08674-1",
    "uniprot_ac": "O08674",
    "uniprot_id": "RBPJL_MOUSE",
    "mass": {
        "chemical_mass": 56780.0,
        "monoisotopic_mass": 56780.0
    },
    "refseq": {
        "ac": "NP_033062",
        "name": "recombining binding protein suppressor of hairless-like protein",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_033062"
    },
    "gene_names": [
        {
            "name": "Rbpjl",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/O08674",
            "id": "O08674"
        },
        {
            "name": "RBP-L; Rbpsuhl",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_033062",
            "id": "NP_033062"
        },
        {
            "name": "Rbpjl",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_033062",
            "id": "NP_033062"
        },
        {
            "name": "Rbpl",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/O08674",
            "id": "O08674"
        },
        {
            "name": "Rbpsuhl",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/O08674",
            "id": "O08674"
        }
    ],
    "protein_names": [
        {
            "name": "Recombining binding protein suppressor of hairless-like protein",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "O08674"
        },
        {
            "name": "Transcription factor RBP-L",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "O08674"
        },
        {
            "name": "recombining binding protein suppressor of hairless-like protein",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_033062",
            "id": "NP_033062"
        },
        {
            "name": "transcription factor RBP-L; RBP-J kappa-like",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_033062",
            "id": "NP_033062"
        }
    ],
    "function": [
        {
            "annotation": "Putative transcription factor, which cooperates with EBNA2 to activate transcription.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O08674",
                    "url": "https://www.uniprot.org/uniprot/O08674#function"
                }
            ]
        },
        {
            "annotation": "RBPJL is the third subunit of an unusual bHLH factor complex that binds and activates pancreatic acinar specific genes",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_033062",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_033062"
                },
                {
                    "database": "PubMed",
                    "id": "16354684",
                    "url": "https://glygen.org/publication/PubMed/16354684"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O08674",
                    "url": "https://www.uniprot.org/uniprot/O08674"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Rbpjl",
            "url": "https://www.uniprot.org/uniprot/O08674",
            "locus": {
                "chromosome": "2",
                "start_pos": 164257368,
                "end_pos": 164245061,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000017007",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000017007"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000017007",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000017007",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd01176",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01176",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "19668",
            "url": "https://www.ncbi.nlm.nih.gov/gene/19668",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "O08674",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:O08674*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR008967",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR008967",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013783",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR014756",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR015350",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR015350",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR015351",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR015351",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036358",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036358",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR037095",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR037095",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR038007",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR038007",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR040159",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR040159",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:19668",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:19668",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "1196616",
            "url": "http://www.informatics.jax.org/marker/MGI:1196616",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "LACAREP",
            "url": "https://omabrowser.org/oma/group/LACAREP/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1384914at2759",
            "url": "http://www.orthodb.org/?query=1384914at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR10665",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10665",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR10665:SF2",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10665:SF2",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF09270",
            "url": "http://pfam.xfam.org/family/PF09270",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF09271",
            "url": "http://pfam.xfam.org/family/PF09271",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF20144",
            "url": "http://pfam.xfam.org/family/PF20144",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_O08674",
            "url": "http://purl.obolibrary.org/obo/PR_O08674",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_033062",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_033062",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "O08674",
            "url": "https://www.uniprot.org/uniprot/O08674",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "O08674-1",
            "url": "https://www.uniprot.org/uniprot/O08674-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MDPRETTDPSLPPGPLTHLSLPDSSEVRLQSDGPSLLGSWTRSPPEHAIILREGVRTCLQQRCEQTVWILHAKVAQKSYGNEKRFFCPPPCVYLAGPGWRVKPMQDQALQSAETGPTVCGYMGLDGASGSAPETQKLNFEEQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGQELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADGHCSQGDFPPQEGYIRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPSDTPGGAGTYLCLATEKVVRFQASLCPKEANRALLNDSSCWTIIGTESVEFTFSTSLACTREPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFGSDWRWLRTPITVPVSLLRADALFYPSPFSFTYTPEYSALPRLPNAQEPAPDADTLLESIHHEFTRTNFHLFCPT",
        "length": 515,
        "header": "sp|O08674-1|RBPJL_MOUSE Isoform 1 of Recombining binding protein suppressor of hairless-like protein  OS=Mus musculus OX=10090 GN=Rbpjl PE=1 SV=1 CANONICAL=O08674-1"
    },
    "isoforms": [
        {
            "isoform_ac": "O08674-1",
            "url": "",
            "sequence": {
                "sequence": "MDPRETTDPSLPPGPLTHLSLPDSSEVRLQSDGPSLLGSWTRSPPEHAIILREGVRTCLQQRCEQTVWILHAKVAQKSYGNEKRFFCPPPCVYLAGPGWRVKPMQDQALQSAETGPTVCGYMGLDGASGSAPETQKLNFEEQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGQELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADGHCSQGDFPPQEGYIRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPSDTPGGAGTYLCLATEKVVRFQASLCPKEANRALLNDSSCWTIIGTESVEFTFSTSLACTREPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFGSDWRWLRTPITVPVSLLRADALFYPSPFSFTYTPEYSALPRLPNAQEPAPDADTLLESIHHEFTRTNFHLFCPT",
                "length": 515,
                "header": "sp|O08674-1|RBPJL_MOUSE Isoform 1 of Recombining binding protein suppressor of hairless-like protein  OS=Mus musculus OX=10090 GN=Rbpjl PE=1 SV=1 CANONICAL=O08674-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 164256560,
                "end_pos": 164245217,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000017151",
                        "url": "https://www.ensembl.org/id/ENSMUST00000017151"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000017151",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000017151"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L.",
            "journal": "Molecular and cellular biology",
            "date": "2006",
            "authors": "Beres TM, Masui T, Swift GH, Shi L, Henke RM, MacDonald RJ",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_033062",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_033062"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "16354684",
                    "url": "https://glygen.org/publication/PubMed/16354684"
                }
            ]
        },
        {
            "title": "RBP-L, a transcription factor related to RBP-Jkappa.",
            "journal": "Mol. Cell. Biol.",
            "date": "1997",
            "authors": "Minoguchi S, Taniguchi Y, Kato H, Okazaki T, Strobl LJ, Zimber-Strobl U, Bornkamm GW, Honjo T",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "O08674",
                    "url": "https://www.uniprot.org/uniprot/O08674"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "9111338",
                    "url": "https://glygen.org/publication/PubMed/9111338"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:19668",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:19668",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "D4AEG0-1",
            "protein_name": "Recombination signal binding protein for immunoglobulin kappa J region-like",
            "gene_name": "Rbpjl",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MNPGETTDPSVPPGPLTHLSLPDSSEVRLQNDGPSLLGSWTRSPPEHATILREGVRTCLQQRCEQTVWILHAKVAQKSYGTEKRFFCPPPCVYLAGPGWRVKPMQDQVHQSADTGPTVCGYMGLDGASGSAPETQKLNFEEQPDSREFGCAKTLFISDADKRKHFRLVLRLVQRGGRELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADGHCSQGDFPPQEGYIRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGDTPGGAGTYLCLSTEKVVRFQASLCPKEANRALLNDSSCWTIIGTESVEFSFSTSLACTPEPVTPVPHISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFGSDWRWLRTPITVPVSLLRADALFYPSAFSFTYTPEYSTRPRPPNAQEPAPDADALLESIHHEFTRTNFHLFCPT",
                "length": 515
            },
            "evidence": [
                {
                    "id": "45226887",
                    "url": "http://www.informatics.jax.org/homology/45226887",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q9UBG7-1",
            "protein_name": "Recombining binding protein suppressor of hairless-like protein",
            "gene_name": "RBPJL",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MDPAGAADPSVPPNPLTHLSLQDRSEMQLQSEADRRSLPGTWTRSSPEHTTILRGGVRRCLQQQCEQTVRILHAKVAQKSYGNEKRFFCPPPCVYLSGPGWRVKPGQDQAHQAGETGPTVCGYMGLDSASGSATETQKLNFEQQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGRELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADGHSAQGDFPPREGYVRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGSPPGGGGTYLCLATEKVVQFQASPCPKEANRALLNDSSCWTIIGTESVEFSFSTSLACTLEPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFCSDWRWLRAPITIPMSLVRADGLFYPSAFSFTYTPEYSVRPGHPGVPEPATDADALLESIHQEFTRTNFHLFIQT",
                "length": 517
            },
            "evidence": [
                {
                    "id": "45226887",
                    "url": "http://www.informatics.jax.org/homology/45226887",
                    "database": "MGI"
                },
                {
                    "id": "O08674",
                    "url": "https://omabrowser.org/oma/group/O08674/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 6,
                "go_terms": [
                    {
                        "name": "DNA binding",
                        "id": "GO:0003677",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O08674",
                                "url": "https://www.uniprot.org/uniprot/O08674"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "chromatin binding",
                        "id": "GO:0003682",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O08674",
                                "url": "https://www.uniprot.org/uniprot/O08674"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding",
                        "id": "GO:0000977",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O08674",
                                "url": "https://www.uniprot.org/uniprot/O08674"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding",
                        "id": "GO:0000978",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O08674",
                                "url": "https://www.uniprot.org/uniprot/O08674"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "DNA-binding transcription factor activity, RNA polymerase II-specific",
                        "id": "GO:0000981",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O08674",
                                "url": "https://www.uniprot.org/uniprot/O08674"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "DNA-binding transcription activator activity, RNA polymerase II-specific",
                        "id": "GO:0001228",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O08674",
                                "url": "https://www.uniprot.org/uniprot/O08674"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O08674",
                                "url": "https://www.uniprot.org/uniprot/O08674"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "transcription regulator complex",
                        "id": "GO:0005667",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O08674",
                                "url": "https://www.uniprot.org/uniprot/O08674"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "positive regulation of transcription by RNA polymerase II",
                        "id": "GO:0045944",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O08674",
                                "url": "https://www.uniprot.org/uniprot/O08674"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of DNA-templated transcription",
                        "id": "GO:0045893",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "O08674",
                                "url": "https://www.uniprot.org/uniprot/O08674"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 352,
            "end_pos": 354,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
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