{ "uniprot_canonical_ac": "M0RBJ3-1", "uniprot_ac": "M0RBJ3", "uniprot_id": "M0RBJ3_RAT", "mass": { "chemical_mass": 34437.0, "monoisotopic_mass": 34437.0 }, "refseq": { "ac": "NP_001000642", "name": "olfactory receptor Olr646", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000642" }, "gene_names": [ { "name": "Or4c102", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/M0RBJ3", "id": "M0RBJ3" }, { "name": "Olr646", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000642", "id": "NP_001000642" }, { "name": "Or4c102", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000642", "id": "NP_001000642" } ], "protein_names": [ { "name": "Olfactory receptor", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "M0RBJ3" }, { "name": "olfactory receptor Olr646", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000642", "id": "NP_001000642" }, { "name": "olfactory receptor gene Olr646; olfactory receptor 646", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000642", "id": "NP_001000642" } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001000642", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000642" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "M0RBJ3", "url": "https://www.uniprot.org/uniprot/M0RBJ3" } ], "common_name": "Rat" } ], "gene": [ { "name": "Or4c102", "url": "https://www.uniprot.org/uniprot/M0RBJ3", "locus": {} } ], "crossref": [ { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "404835", "url": "https://www.ncbi.nlm.nih.gov/gene/404835", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:404835", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:404835", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ATMITPM", "url": "https://omabrowser.org/oma/group/ATMITPM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "4052270at2759", "url": "http://www.orthodb.org/?query=4052270at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "http://pfam.xfam.org/family/PF13853", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001000642", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000642", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1333370", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1333370", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A8I6AAS3", "url": "https://www.uniprot.org/uniprot/A0A8I6AAS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6AAS3-1", "url": "https://www.uniprot.org/uniprot/A0A8I6AAS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M0RBJ3", "url": "https://www.uniprot.org/uniprot/M0RBJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M0RBJ3-1", "url": "https://www.uniprot.org/uniprot/M0RBJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMNKNNVTEFILLGITSDPELRKMLSVLFLIMYMITIFGNLLIVVTITRSPSLRSPMYFFLLSLSLMDVTYSSVIAPKLIIDSLSERTIVSFEGCMAQLFAEHFFGGVGIILLIVMAYDRYVAICKPLHYTKIMTPNVCCLMVGGAWVGGSMHATIQLLFMYQIPFCSPNIIDHFMCDLFPLLKLACMDTYILGLLVILNSGVMCVSIFLILIASYIVILCSLKSYSSEGRRKALSTCSSHFTVVVLFFVPCIFLYMRPVVTFPIDKAMAVSFTIVEPMLNPLIYTLRNAEVKYAIKNMCRKQGCH", "length": 306, "header": "tr|M0RBJ3-1|M0RBJ3_RAT Isoform 1 of Olfactory receptor OS=Rattus norvegicus OX=10116 GN=Or4c102 PE=3 SV=2 CANONICAL=M0RBJ3-1" }, "isoforms": [ { "isoform_ac": "A0A8I6AAS3-1", "url": "", "sequence": { "sequence": "MWIISWILQVYFFLLTKMMNKNNVTEFILLGITSDPELRKMLSVLFLIMYMITIFGNLLIVVTITRSPSLRSPMYFFLLSLSLMDVTYSSVIAPKLIIDSLSERTIVSFEGCMAQLFAEHFFGGVGIILLIVMAYDRYVAICKPLHYTKIMTPNVCCLMVGGAWVGGSMHATIQLLFMYQIPFCSPNIIDHFMCDLFPLLKLACMDTYILGLLVILNSGVMCVSIFLILIASYIVILCSLKSYSSEGRRKALSTCSSHFTVVVLFFVPCIFLYMRPVVTFPIDKAMAVSFTIVEPMLNPLIYTLRNAEVKYAIKNMCRKQGCH", "length": 323, "header": "tr|A0A8I6AAS3-1|M0RBJ3_RAT Computationally mapped isoform of Olfactory receptor OS=Rattus norvegicus OX=10116 GN=Or4c102 PE=3 SV=1 CANONICAL=M0RBJ3-1" }, "locus": { "chromosome": "3", "start_pos": 74324189, "end_pos": 74321758, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000117192.1", "url": "https://www.ensembl.org/id/ENSRNOT00000117192.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000088415.1", "url": "https://www.ensembl.org/id/ENSRNOP00000088415.1" } ] } }, { "isoform_ac": "M0RBJ3-1", "url": "", "sequence": { "sequence": "MMNKNNVTEFILLGITSDPELRKMLSVLFLIMYMITIFGNLLIVVTITRSPSLRSPMYFFLLSLSLMDVTYSSVIAPKLIIDSLSERTIVSFEGCMAQLFAEHFFGGVGIILLIVMAYDRYVAICKPLHYTKIMTPNVCCLMVGGAWVGGSMHATIQLLFMYQIPFCSPNIIDHFMCDLFPLLKLACMDTYILGLLVILNSGVMCVSIFLILIASYIVILCSLKSYSSEGRRKALSTCSSHFTVVVLFFVPCIFLYMRPVVTFPIDKAMAVSFTIVEPMLNPLIYTLRNAEVKYAIKNMCRKQGCH", "length": 306, "header": "tr|M0RBJ3-1|M0RBJ3_RAT Isoform 1 of Olfactory receptor OS=Rattus norvegicus OX=10116 GN=Or4c102 PE=3 SV=2 CANONICAL=M0RBJ3-1" }, "locus": { "chromosome": "3", "start_pos": 74324189, "end_pos": 74323272, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000074443.3", "url": "https://www.ensembl.org/id/ENSRNOT00000074443.3" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000066930.2", "url": "https://www.ensembl.org/id/ENSRNOP00000066930.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "rno:404835", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:404835", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2AV11-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c102", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMNKNNVTEFILLGVTRDPELRKILSVLFLIMYMATVFGNLLIVVTITRSPSLRSPMYFFLLSLSLMDVTYSSVIAPKLIMDSLSERTIVSFERCMTQLFAEHFFGGVGIILLIVMAYDRYVAICKPLHYVKMMTPRVCCLMVGGAWVGGSMHATIQLLFMYQIPFCSSNIIDHFMCDLFPLLKLACMDTHILGLLVILNSGVMCVSIFLILIASYMVILCSLKSYSSEGRRKALSTCSSHFTVVVLFFVPCIFLYMRPVVTFPIDKAMAVSFTIVEPMLNPLIYTLRNTEVKYAIKNMCRKQGSH", "length": 306 }, "evidence": [ { "id": "45242864", "url": "http://www.informatics.jax.org/homology/45242864", "database": "MGI" } ], "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NH72-1", "protein_name": "Olfactory receptor 4C6", "gene_name": "OR4C6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENQNNVTEFILLGLTENLELWKIFSAVFLVMYVATVLENLLIVVTIITSQSLRSPMYFFLTFLSLLDVMFSSVVAPKVIVDTLSKSTTISLKGCLTQLFVEHFFGGVGIILLTVMAYDRYVAICKPLHYTIIMSPRVCCLMVGGAWVGGFMHAMIQLLFMYQIPFCGPNIIDHFICDLFQLLTLACTDTHILGLLVTLNSGMMCVAIFLILIASYTVILCSLKSYSSKGRHKALSTCSSHLTVVVLFFVPCIFLYMRPVVTHPIDKAMAVSDSIITPMLNPLIYTLRNAEVKSAMKKLWMKWEALAGK", "length": 309 }, "evidence": [ { "id": "45242864", "url": "http://www.informatics.jax.org/homology/45242864", "database": "MGI" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "M0RBJ3", "url": "https://www.uniprot.org/uniprot/M0RBJ3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "M0RBJ3", "url": "https://www.uniprot.org/uniprot/M0RBJ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0RBJ3", "url": "https://www.uniprot.org/uniprot/M0RBJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 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