{
    "uniprot_canonical_ac": "M0R8A3-1",
    "uniprot_ac": "M0R8A3",
    "uniprot_id": "M0R8A3_RAT",
    "mass": {
        "chemical_mass": 35022.0,
        "monoisotopic_mass": 35022.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Gp6",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/M0R8A3",
            "id": "M0R8A3"
        }
    ],
    "protein_names": [
        {
            "name": "Glycoprotein 6 (platelet)",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "M0R8A3"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0111057",
            "recommended_name": {
                "id": "DOID:0111057",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0111057",
                "name": "platelet-type bleeding disorder 11",
                "description": "A blood platelet disease characterized by autosomal recessive inheritance of mild to moderate bleeding and defective platelet activation and aggregation in response to collagen that has_material_basis_in compound heterozygous mutation in the GP6 gene on chromosome 19q13."
            },
            "synonyms": [
                {
                    "id": "DOID:0111057",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111057",
                    "name": "BDPLT11",
                    "description": ""
                },
                {
                    "id": "DOID:0111057",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111057",
                    "name": "GP VI deficiency",
                    "description": ""
                },
                {
                    "id": "DOID:0111057",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111057",
                    "name": "glycoprotein VI deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0013623",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013623",
                    "name": "platelet-type bleeding disorder 11",
                    "description": "Any inherited bleeding disorder, platelet-type in which the cause of the disease is a mutation in the GP6 gene."
                },
                {
                    "id": "MONDO:0013623",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013623",
                    "name": "BDPLT11",
                    "description": ""
                },
                {
                    "id": "MONDO:0013623",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013623",
                    "name": "GP VI deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0013623",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013623",
                    "name": "GP6 inherited bleeding disorder, platelet-type",
                    "description": ""
                },
                {
                    "id": "MONDO:0013623",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013623",
                    "name": "glycoprotein VI deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0013623",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013623",
                    "name": "inherited bleeding disorder, platelet-type caused by mutation in GP6",
                    "description": ""
                },
                {
                    "id": "MONDO:0013623",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013623",
                    "name": "platelet-type bleeding disorder 11",
                    "description": ""
                },
                {
                    "id": "MONDO:0013623",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013623",
                    "name": "GP 6 deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0013623",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013623",
                    "name": "bleeding diathesis due to glycoprotein VI deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0013623",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013623",
                    "name": "bleeding disorder, platelet-type, 11",
                    "description": ""
                },
                {
                    "id": "MONDO:0013623",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013623",
                    "name": "glycoprotein 6 deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0013623",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013623",
                    "name": "platelet-type bleeding disorder-11",
                    "description": ""
                },
                {
                    "id": "MIM:614201",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/614201",
                    "name": "Bleeding disorder, platelet-type, 11",
                    "description": "Bleeding disorder, platelet-type, 11"
                }
            ],
            "evidence": [
                {
                    "id": "0111057",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111057"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
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                    "database": "UniProtKB",
                    "id": "M0R8A3",
                    "url": "https://www.uniprot.org/uniprot/M0R8A3"
                }
            ],
            "common_name": "Rat"
        }
    ],
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            "name": "Gp6",
            "url": "https://www.uniprot.org/uniprot/M0R8A3",
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                "end_pos": 69465789,
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                        "id": "ENSRNOG00000047204",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000047204"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000047204",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000047204",
            "database": "Bgee",
            "categories": [
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            ]
        },
        {
            "id": "IPR003598",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR003599",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013783",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036179",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "GPARQHY",
            "url": "https://omabrowser.org/oma/group/GPARQHY/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11738",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11738",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR11738:SF185",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11738:SF185",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF13895",
            "url": "http://pfam.xfam.org/family/PF13895",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-114604",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-114604",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-202733",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-202733",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-75892",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-75892",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1589130",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1589130",
            "database": "RGD",
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                "Organism-specific"
            ]
        },
        {
            "id": "M0R8A3",
            "url": "https://www.uniprot.org/uniprot/M0R8A3",
            "database": "UniProtKB",
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                "Protein"
            ]
        },
        {
            "id": "M0R8A3-1",
            "url": "https://www.uniprot.org/uniprot/M0R8A3-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
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        "length": 315,
        "header": "tr|M0R8A3-1|M0R8A3_RAT Isoform 1 of Glycoprotein 6 (platelet)  OS=Rattus norvegicus OX=10116 GN=Gp6 PE=4 SV=1 CANONICAL=M0R8A3-1"
    },
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        {
            "isoform_ac": "M0R8A3-1",
            "url": "",
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                "sequence": "MSPASLTFFCIGLCVLQVIQAQHGPLPKPSLQAQPSSLVPLGHPVTLRCLGPSDADLYRLEKVKPGKLIFIDQDFLFIPIMEINNAGRYRCSYQNESHWSLPSDQLELIATGVYSKPSLSAHPSSAIPPGRDVTLKCQSQYSFDEFVLYKEGDTRPYKRPEKWYRANFPVITVTAAHSGTYRCYSFSSSSPYLWSAPSDPLVVVVTGPSATPSQVPTEVPSPMTEASRRPSMLLTNKISTTEKPMNITVSPEGPSPPFGFAHQHYAKGNLVRICLGVMIIMFLVGFLAEDWHSRKKRLQHRIRAMQRPLPPLPLA",
                "length": 315,
                "header": "tr|M0R8A3-1|M0R8A3_RAT Isoform 1 of Glycoprotein 6 (platelet)  OS=Rattus norvegicus OX=10116 GN=Gp6 PE=4 SV=1 CANONICAL=M0R8A3-1"
            },
            "locus": {
                "chromosome": "1",
                "start_pos": 69491194,
                "end_pos": 69465887,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000071927.4",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000071927.4"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000065697.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000065697.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "R-RNO-114604",
            "name": "GPVI-mediated activation cascade",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-114604",
            "resource": "Reactome",
            "description": "GPVI-mediated activation cascade"
        },
        {
            "id": "R-RNO-202733",
            "name": "Cell surface interactions at the vascular wall",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-202733",
            "resource": "Reactome",
            "description": "Cell surface interactions at the vascular wall"
        },
        {
            "id": "R-RNO-75892",
            "name": "Platelet Adhesion to exposed collagen",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-75892",
            "resource": "Reactome",
            "description": "Platelet Adhesion to exposed collagen"
        }
    ],
    "orthologs": [],
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        "categories": [
            {
                "name": "Cellular Component",
                "total": 4,
                "go_terms": [
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
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                                "id": "M0R8A3",
                                "url": "https://www.uniprot.org/uniprot/M0R8A3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell surface",
                        "id": "GO:0009986",
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                                "id": "M0R8A3",
                                "url": "https://www.uniprot.org/uniprot/M0R8A3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "membrane raft",
                        "id": "GO:0045121",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121",
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                                "id": "M0R8A3",
                                "url": "https://www.uniprot.org/uniprot/M0R8A3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "tetraspanin-enriched microdomain",
                        "id": "GO:0097197",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097197",
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                                "id": "M0R8A3",
                                "url": "https://www.uniprot.org/uniprot/M0R8A3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 4,
                "go_terms": [
                    {
                        "name": "peptidyl-tyrosine phosphorylation",
                        "id": "GO:0018108",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018108",
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                            {
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                                "id": "M0R8A3",
                                "url": "https://www.uniprot.org/uniprot/M0R8A3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
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                        "id": "GO:0070527",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070527",
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                                "id": "M0R8A3",
                                "url": "https://www.uniprot.org/uniprot/M0R8A3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "collagen-activated tyrosine kinase receptor signaling pathway",
                        "id": "GO:0038063",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038063",
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                                "id": "M0R8A3",
                                "url": "https://www.uniprot.org/uniprot/M0R8A3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
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                        "id": "GO:0038065",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038065",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "M0R8A3",
                                "url": "https://www.uniprot.org/uniprot/M0R8A3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 3,
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                    {
                        "name": "collagen binding",
                        "id": "GO:0005518",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518",
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                                "id": "M0R8A3",
                                "url": "https://www.uniprot.org/uniprot/M0R8A3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein tyrosine kinase binding",
                        "id": "GO:1990782",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990782",
                        "evidence": [
                            {
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                                "id": "M0R8A3",
                                "url": "https://www.uniprot.org/uniprot/M0R8A3"
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                        ],
                        "pmid": ""
                    },
                    {
                        "name": "collagen receptor activity",
                        "id": "GO:0038064",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038064",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "M0R8A3",
                                "url": "https://www.uniprot.org/uniprot/M0R8A3"
                            }
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                        "pmid": ""
                    }
                ]
            }
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            "end_pos": 248,
            "annotation": "n_glycosylation_sequon"
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        {
            "start_pos": 95,
            "end_pos": 97,
            "annotation": "n_glycosylation_sequon"
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    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
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    "cluster_types": [],
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