{
    "uniprot_canonical_ac": "G3V674-1",
    "uniprot_ac": "G3V674",
    "uniprot_id": "G3V674_RAT",
    "mass": {
        "chemical_mass": 28488.0,
        "monoisotopic_mass": 28488.0
    },
    "refseq": {
        "ac": "NP_001006956",
        "name": "claudin domain-containing protein 1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006956"
    },
    "gene_names": [
        {
            "name": "Cldnd1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/G3V674",
            "id": "G3V674"
        },
        {
            "name": "Cldnd1",
            "resource": "RefSeq",
            "type": "synonym",
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            "id": "NP_001006956"
        }
    ],
    "protein_names": [
        {
            "name": "Claudin domain containing 1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "G3V674"
        },
        {
            "name": "claudin domain-containing protein 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006956",
            "id": "NP_001006956"
        }
    ],
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        {
            "annotation": "When miR-124 is increased, CLDND1 mRNA translation is downregulated in the brain.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001006956",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006956"
                },
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                    "database": "PubMed",
                    "id": "29530526",
                    "url": "https://glygen.org/publication/PubMed/29530526"
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            ]
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    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
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                    "database": "UniProtKB",
                    "id": "G3V674",
                    "url": "https://www.uniprot.org/uniprot/G3V674"
                }
            ],
            "common_name": "Rat"
        }
    ],
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            "name": "Cldnd1",
            "url": "https://www.uniprot.org/uniprot/G3V674",
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                "end_pos": 41889354,
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                        "id": "ENSRNOG00000001657",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000001657"
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        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000001657",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000001657",
            "database": "Bgee",
            "categories": [
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        },
        {
            "id": "288182",
            "url": "https://www.ncbi.nlm.nih.gov/gene/288182",
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        {
            "id": "IPR004031",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR004031",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR042356",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR042356",
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            "categories": [
                "Protein Classification"
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            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:288182",
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            "categories": [
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        {
            "id": "NTHWYSP",
            "url": "https://omabrowser.org/oma/group/NTHWYSP/",
            "database": "OMA",
            "categories": [
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        },
        {
            "id": "5294768at2759",
            "url": "http://www.orthodb.org/?query=5294768at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR14347",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14347",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR14347:SF3",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14347:SF3",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF13903",
            "url": "http://pfam.xfam.org/family/PF13903",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001006956",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006956",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1359273",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1359273",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "G3V674",
            "url": "https://www.uniprot.org/uniprot/G3V674",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "G3V674-1",
            "url": "https://www.uniprot.org/uniprot/G3V674-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
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        "sequence": "MDNRFATAFVIACVLSLISTIYMAASIGTDFWYEYQSPAQENSSDANRIAWEDFMGDEADEKTYNDALFRYNGNLGLWRRCITIPKNTHWYAPPERTESFEVVTKCMSFTLNEQFMEKYVDPGNHNSGIDLLRTYLWRCQFLLPFVSLGLMCFGALIGLCACVCRSLYPTIATGILHLLAGLCTLGSVSCYVAGIELLHQKLGLPKNVSGEFGWSFCLACVSAPLQFMASALFIWAAHTNRKEYTLMKAYRVA",
        "length": 253,
        "header": "tr|G3V674-1|G3V674_RAT Isoform 1 of Claudin domain containing 1  OS=Rattus norvegicus OX=10116 GN=Cldnd1 PE=4 SV=1 CANONICAL=G3V674-1"
    },
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            "isoform_ac": "G3V674-1",
            "url": "",
            "sequence": {
                "sequence": "MDNRFATAFVIACVLSLISTIYMAASIGTDFWYEYQSPAQENSSDANRIAWEDFMGDEADEKTYNDALFRYNGNLGLWRRCITIPKNTHWYAPPERTESFEVVTKCMSFTLNEQFMEKYVDPGNHNSGIDLLRTYLWRCQFLLPFVSLGLMCFGALIGLCACVCRSLYPTIATGILHLLAGLCTLGSVSCYVAGIELLHQKLGLPKNVSGEFGWSFCLACVSAPLQFMASALFIWAAHTNRKEYTLMKAYRVA",
                "length": 253,
                "header": "tr|G3V674-1|G3V674_RAT Isoform 1 of Claudin domain containing 1  OS=Rattus norvegicus OX=10116 GN=Cldnd1 PE=4 SV=1 CANONICAL=G3V674-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 41887904,
                "end_pos": 41884296,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000002260.5",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000002260.5"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000002260.3",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000002260.3"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Levels of tight junction protein CLDND1 are regulated by microRNA-124 in the cerebellum of stroke-prone spontaneously hypertensive rats.",
            "journal": "Biochemical and biophysical research communications",
            "date": "2018",
            "authors": "Matsuoka H, Tamura A, Kinehara M, Shima A, Uda A, Tahara H, Michihara A",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001006956",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006956"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "29530526",
                    "url": "https://glygen.org/publication/PubMed/29530526"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:288182",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:288182",
            "resource": "KEGG Pathway"
        }
    ],
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        {
            "uniprot_canonical_ac": "Q9CQX5-1",
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            "gene_name": "Cldnd1",
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                "length": 253
            },
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                "name": "Cellular Component",
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                "go_terms": [
                    {
                        "name": "apical plasma membrane",
                        "id": "GO:0016324",
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    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
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            "name": "homologset.mgi",
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