{ "uniprot_canonical_ac": "F1M8G6-1", "uniprot_ac": "F1M8G6", "uniprot_id": "F1M8G6_RAT", "mass": { "chemical_mass": 351898.0, "monoisotopic_mass": 351898.0 }, "refseq": { "ac": "NP_001077435", "name": "DNA polymerase zeta catalytic subunit", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077435" }, "gene_names": [ { "name": "Rev3l", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/F1M8G6", "id": "F1M8G6" }, { "name": "Rev3l", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077435", "id": "NP_001077435" } ], "protein_names": [ { "name": "DNA polymerase zeta catalytic subunit", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "F1M8G6" }, { "name": "2.7.7.7", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "F1M8G6" }, { "name": "DNA polymerase zeta catalytic subunit", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077435", "id": "NP_001077435" }, { "name": "REV3-like, polymerase (DNA directed), zeta, catalytic subunit; REV3-like, catalytic subunit of DNA polymerase zeta", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077435", "id": "NP_001077435" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M8G6", "url": "https://www.uniprot.org/uniprot/F1M8G6" } ], "common_name": "Rat" } ], "gene": [ { "name": "Rev3l", "url": "https://www.uniprot.org/uniprot/F1M8G6", "locus": { "chromosome": "20", "start_pos": 43290099, "end_pos": 43132363, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000000593", "url": "https://www.ensembl.org/id/ENSRNOG00000000593" } ] } } ], "crossref": [ { "id": "ENSRNOG00000000593", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000000593", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05534", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05534", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05778", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05778", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22287", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22287", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "309812", "url": "https://www.ncbi.nlm.nih.gov/gene/309812", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025687", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025687", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030559", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030559", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:309812", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:309812", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DPTSWIR", "url": "https://omabrowser.org/oma/group/DPTSWIR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "211439at2759", "url": "http://www.orthodb.org/?query=211439at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45812", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45812", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45812:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45812:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00136", "url": "http://pfam.xfam.org/family/PF00136", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF03104", "url": "http://pfam.xfam.org/family/PF03104", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF14260", "url": "http://pfam.xfam.org/family/PF14260", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF15735", "url": "http://pfam.xfam.org/family/PF15735", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "R-RNO-110312", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-110312", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-RNO-5655862", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5655862", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-RNO-5656121", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5656121", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-RNO-5656169", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5656169", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_001077435", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077435", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1307087", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1307087", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "22508", "url": "https://www.rhea-db.org/rhea/22508", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1M8G6", "url": "https://www.uniprot.org/uniprot/F1M8G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1M8G6-1", "url": "https://www.uniprot.org/uniprot/F1M8G6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSVRIVTADYYMASPLPGLDICQSPLTQHPVKKVPVVRVFGATPAGQKTCLHLHGVFPYLYVPYDGYGQQPERYLSQMALSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYHEKERHFMKIYLYNPAMVKRICELLQSGAIMNKFYQPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKGDASHATGLFKPQLSGNSPAGTLFRWEEDEIPSSLLLEGVEPLSTCELEVDAVAADILNRLDIEAQIGGNPGLQAIWEDEKQRRRNRNENSQISQPESQDCRLVPATESEKIFQKRLQEILKQNDFSVTLSGSVDYSSGSQEFSAELTLHSEILSPEMLPCSPANMIEVHRDNDWSKGNTKHKVEEALINEEAILNLIENSQTFQPLTQRLSETPVFMDSSPDESLVHLLAGLESDGYQGEKNRMPLPRHTFGESQNPQNSDDEENAPQMEKEEMELSVLMSQRWDSDTEEQCAKKRSLCRNAHRSSTEEDDSSSEEEMEWTDNSLLFANLSIPQLDGTADENSDNPLNNENSRAHSSVIATSKLSVRPSVFHKDAATLEPPSSAKITFQCKHTSALSSHGLNKDDLIEGLSQPNNTEKGRDSSVTFTKESTYSMKYSGSLSSTVHSDNSHKEICKKDKSLPVPSCESSVFDYEEDIPSVTRQAPSRKYSNMRKIEKDAPFIHANRHTSESTLGKNSFNFADLNHSKNKLSSEGNERGNSTALNSVFPSSLAESCDLLSSSGENRSVAHSLDSITDESGRSKLKIRYEEFQEHKMERPSLSQQAAHYMFFPSVVLSNCLTRPQKLSPVTYKLQPGSKTSRLKLNKKKLISLQETSTKSSETGAAKDSCTHNHPYSGTPEKESGLSSDLIKATHGTFENKTPTEHFIDCHFGDGSLETEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTHNSKISLPHPMEIGENLDGTLKSRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKRKPGKQHRASSENIKRTLSFRKKRTHAVLSPPSPSYIAETEDCDLNYSDVMSKLGFLSERSTSPVNSSPPRCWSPTDPRAEEIMAAAEKESVLFKGPNVCNTKTVSPRVGKASRARAQVKKSKARLAKSSVVTNKRNKRNQTNQLVDNGKKKPRAKQKQRANEKGISRKPVIPTDETTKPPSEAELTPSQRSVPELTSSSGIHTLSKQKEMTQTGPAMDHPLPPCQPTGINAQQRLSNCFSSFLESRKSVQFPTFPSSRGDSRSSVYSSIGPGVSKVNTQRSHSQSAMFTRKETTLIQKSIFDLSNHLSQVAQSTQLCSGIISPKTEESSNTQKNCGSSIGKLNEYRSSLESKPEKVCAPNFLHCRDSQQQTVNVSEQSKPSETCSPGNAASEESQTPNCFVTSLRSPIKQITWEQRQRGCILEMSSFKPEKVKQRSLSEAISQTKALSQCKNQNVSTPSVFGEGQSGLAVLKELLQKRQQKAQTTNVQDSASSHQPDKDISVSAEHKKTNKRTRAVASPRKPRAPRRTKPKEQTPRRLKVDPLNLQTSGHLDNSLSDDSPILFSDPGFESCYSLEDSLSPEHNYNFDINTIGQTGFCSLYSGSQFVPADQNLPQKFLSDAVQDLFPGQAIEKNELLSHDRQSCTEEKHHVSDSGPWVRASTLNPELFEKVGIDNNENHRHSQWKTSFHPLTSHSNSIMESFCVQQAESCLPEKSRLNRSSVSKEVFLSLPQASSSDWIQGHNGKEIEQSLDSANTSFTTVLSSPDGELVDAASEDLELYVSRNNDVLTPTPDSSPRSTSSPLQSKNGSFTPRTAHILKPLMSPPSREEIVATLLDHDLSEAIYQEPFCSNPSDVPEKPREIGGRLLMVETRLPNDLIEFEGDFSLEGLRLWKTAFSAMTQNPRPGSPLRNGPAVVNKESSNSHKTVEDKKIVIMPCRYAPSRQLVQAWLQAKEEYVRSKRLPRTESTPVIKSADNVSPSLNPGDTRAVAPQMDTCPHTLSSTAHAKEEVCQSQIALQTSRTGCGQTVSASQTLLPAASAAVPEEEEEEEEEEEEEEEDENGYVSYSSPDSPGIPPWQQAASPDFRALNGEHRCSSPVEELCSRAVENFLKPIKDGIQKASCCESQVISPIHARTRTEKCEPLCLHSTPVMPRKFLEKLPEATGLSPLSVEPKTQKLYNKKGSDTDHLRRVLLTTQVENQFAAVNTPKKETSQIDGPSLNNTYGFKVSIQNLQEAKALHEIQNLTLISVELHARTRRDLQPDPEFDPICALFYCISSDTPLPDTEKTELTGVIVIDKDKTVTHQDIRCQTPLLIRSGVTGLEVTYAADEKALFQEVTNIMKRYDPDILLGYEIQMHSWGYLLQRAAALSVDLCQMISRVPDDKIENRFAAERDDYGSDTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLSDWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVTPSVQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHIENLGKYDEFKFGCTSLRVPPDLLYQIRHDITVSPNGVAFVKPSVRKGVLPRMLEEILKTRFMVKQSMKAYRQDRALSRMLNARQLGLKLIANVTFGYTSANFSGRMPCIEVGDSIVHKARETLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLVEGKASIQDFIFAKEYRGSFSYRPGACVPALELTRKMLAYDRRSEPRVGERVPYVIVYGTPGLPLIQLIRRPAEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYQELPRIQKATSSSRSDLEGRKGTISQYFTTLHCPVCDGLTQHGICSQCRSQPQHVAIILNQEIRELERQQEQLVKICRNCTGSFDRHIPCVSLNCPVLFKLSRVNRELSKAPYLRQLLDQF", "length": 3132, "header": "tr|F1M8G6-1|F1M8G6_RAT Isoform 1 of DNA polymerase zeta catalytic subunit OS=Rattus norvegicus OX=10116 GN=Rev3l PE=3 SV=1 CANONICAL=F1M8G6-1" }, "isoforms": [ { "isoform_ac": "F1M8G6-1", "url": "", "sequence": { "sequence": "MFSVRIVTADYYMASPLPGLDICQSPLTQHPVKKVPVVRVFGATPAGQKTCLHLHGVFPYLYVPYDGYGQQPERYLSQMALSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYHEKERHFMKIYLYNPAMVKRICELLQSGAIMNKFYQPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKGDASHATGLFKPQLSGNSPAGTLFRWEEDEIPSSLLLEGVEPLSTCELEVDAVAADILNRLDIEAQIGGNPGLQAIWEDEKQRRRNRNENSQISQPESQDCRLVPATESEKIFQKRLQEILKQNDFSVTLSGSVDYSSGSQEFSAELTLHSEILSPEMLPCSPANMIEVHRDNDWSKGNTKHKVEEALINEEAILNLIENSQTFQPLTQRLSETPVFMDSSPDESLVHLLAGLESDGYQGEKNRMPLPRHTFGESQNPQNSDDEENAPQMEKEEMELSVLMSQRWDSDTEEQCAKKRSLCRNAHRSSTEEDDSSSEEEMEWTDNSLLFANLSIPQLDGTADENSDNPLNNENSRAHSSVIATSKLSVRPSVFHKDAATLEPPSSAKITFQCKHTSALSSHGLNKDDLIEGLSQPNNTEKGRDSSVTFTKESTYSMKYSGSLSSTVHSDNSHKEICKKDKSLPVPSCESSVFDYEEDIPSVTRQAPSRKYSNMRKIEKDAPFIHANRHTSESTLGKNSFNFADLNHSKNKLSSEGNERGNSTALNSVFPSSLAESCDLLSSSGENRSVAHSLDSITDESGRSKLKIRYEEFQEHKMERPSLSQQAAHYMFFPSVVLSNCLTRPQKLSPVTYKLQPGSKTSRLKLNKKKLISLQETSTKSSETGAAKDSCTHNHPYSGTPEKESGLSSDLIKATHGTFENKTPTEHFIDCHFGDGSLETEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTHNSKISLPHPMEIGENLDGTLKSRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKRKPGKQHRASSENIKRTLSFRKKRTHAVLSPPSPSYIAETEDCDLNYSDVMSKLGFLSERSTSPVNSSPPRCWSPTDPRAEEIMAAAEKESVLFKGPNVCNTKTVSPRVGKASRARAQVKKSKARLAKSSVVTNKRNKRNQTNQLVDNGKKKPRAKQKQRANEKGISRKPVIPTDETTKPPSEAELTPSQRSVPELTSSSGIHTLSKQKEMTQTGPAMDHPLPPCQPTGINAQQRLSNCFSSFLESRKSVQFPTFPSSRGDSRSSVYSSIGPGVSKVNTQRSHSQSAMFTRKETTLIQKSIFDLSNHLSQVAQSTQLCSGIISPKTEESSNTQKNCGSSIGKLNEYRSSLESKPEKVCAPNFLHCRDSQQQTVNVSEQSKPSETCSPGNAASEESQTPNCFVTSLRSPIKQITWEQRQRGCILEMSSFKPEKVKQRSLSEAISQTKALSQCKNQNVSTPSVFGEGQSGLAVLKELLQKRQQKAQTTNVQDSASSHQPDKDISVSAEHKKTNKRTRAVASPRKPRAPRRTKPKEQTPRRLKVDPLNLQTSGHLDNSLSDDSPILFSDPGFESCYSLEDSLSPEHNYNFDINTIGQTGFCSLYSGSQFVPADQNLPQKFLSDAVQDLFPGQAIEKNELLSHDRQSCTEEKHHVSDSGPWVRASTLNPELFEKVGIDNNENHRHSQWKTSFHPLTSHSNSIMESFCVQQAESCLPEKSRLNRSSVSKEVFLSLPQASSSDWIQGHNGKEIEQSLDSANTSFTTVLSSPDGELVDAASEDLELYVSRNNDVLTPTPDSSPRSTSSPLQSKNGSFTPRTAHILKPLMSPPSREEIVATLLDHDLSEAIYQEPFCSNPSDVPEKPREIGGRLLMVETRLPNDLIEFEGDFSLEGLRLWKTAFSAMTQNPRPGSPLRNGPAVVNKESSNSHKTVEDKKIVIMPCRYAPSRQLVQAWLQAKEEYVRSKRLPRTESTPVIKSADNVSPSLNPGDTRAVAPQMDTCPHTLSSTAHAKEEVCQSQIALQTSRTGCGQTVSASQTLLPAASAAVPEEEEEEEEEEEEEEEDENGYVSYSSPDSPGIPPWQQAASPDFRALNGEHRCSSPVEELCSRAVENFLKPIKDGIQKASCCESQVISPIHARTRTEKCEPLCLHSTPVMPRKFLEKLPEATGLSPLSVEPKTQKLYNKKGSDTDHLRRVLLTTQVENQFAAVNTPKKETSQIDGPSLNNTYGFKVSIQNLQEAKALHEIQNLTLISVELHARTRRDLQPDPEFDPICALFYCISSDTPLPDTEKTELTGVIVIDKDKTVTHQDIRCQTPLLIRSGVTGLEVTYAADEKALFQEVTNIMKRYDPDILLGYEIQMHSWGYLLQRAAALSVDLCQMISRVPDDKIENRFAAERDDYGSDTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLSDWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVTPSVQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHIENLGKYDEFKFGCTSLRVPPDLLYQIRHDITVSPNGVAFVKPSVRKGVLPRMLEEILKTRFMVKQSMKAYRQDRALSRMLNARQLGLKLIANVTFGYTSANFSGRMPCIEVGDSIVHKARETLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLVEGKASIQDFIFAKEYRGSFSYRPGACVPALELTRKMLAYDRRSEPRVGERVPYVIVYGTPGLPLIQLIRRPAEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYQELPRIQKATSSSRSDLEGRKGTISQYFTTLHCPVCDGLTQHGICSQCRSQPQHVAIILNQEIRELERQQEQLVKICRNCTGSFDRHIPCVSLNCPVLFKLSRVNRELSKAPYLRQLLDQF", "length": 3132, "header": "tr|F1M8G6-1|F1M8G6_RAT Isoform 1 of DNA polymerase zeta catalytic subunit OS=Rattus norvegicus OX=10116 GN=Rev3l PE=3 SV=1 CANONICAL=F1M8G6-1" }, "locus": { "chromosome": "20", "start_pos": 43289123, "end_pos": 43132680, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000057227.4", "url": "https://www.ensembl.org/id/ENSRNOT00000057227.4" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000054053.2", "url": "https://www.ensembl.org/id/ENSRNOP00000054053.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "rno:309812", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:309812", "resource": "KEGG Pathway" }, { "id": "R-RNO-110312", "name": "Translesion synthesis by REV1", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-110312", "resource": "Reactome", "description": "Translesion synthesis by REV1" }, { "id": "R-RNO-5655862", "name": "Translesion synthesis by POLK", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5655862", "resource": "Reactome", "description": "Translesion synthesis by POLK" }, { "id": "R-RNO-5656121", "name": "Translesion synthesis by POLI", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5656121", "resource": "Reactome", "description": "Translesion synthesis by POLI" }, { "id": "R-RNO-5656169", "name": "Termination of translesion DNA synthesis", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5656169", "resource": "Reactome", "description": "Termination of translesion DNA synthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "Q61493-1", "protein_name": "DNA polymerase zeta catalytic subunit", "gene_name": "Rev3l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 3122 }, "evidence": [ { "id": "45233428", "url": "http://www.informatics.jax.org/homology/45233428", "database": "MGI" } ], "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA-directed DNA polymerase activity", "id": "GO:0003887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003887", "evidence": [ { "database": "UniProtKB", "id": "F1M8G6", "url": "https://www.uniprot.org/uniprot/F1M8G6" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1M8G6", "url": "https://www.uniprot.org/uniprot/F1M8G6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1M8G6", "url": "https://www.uniprot.org/uniprot/F1M8G6" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "F1M8G6", "url": "https://www.uniprot.org/uniprot/F1M8G6" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "F1M8G6", "url": "https://www.uniprot.org/uniprot/F1M8G6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1M8G6", "url": "https://www.uniprot.org/uniprot/F1M8G6" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1M8G6", "url": "https://www.uniprot.org/uniprot/F1M8G6" } ], "pmid": "" }, { "name": "zeta DNA polymerase complex", "id": "GO:0016035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016035", "evidence": [ { "database": "UniProtKB", "id": "F1M8G6", "url": "https://www.uniprot.org/uniprot/F1M8G6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "F1M8G6", "url": "https://www.uniprot.org/uniprot/F1M8G6" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "F1M8G6", "url": "https://www.uniprot.org/uniprot/F1M8G6" } ], "pmid": "" }, { "name": "error-prone translesion synthesis", "id": "GO:0042276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042276", "evidence": [ { "database": "UniProtKB", "id": "F1M8G6", "url": "https://www.uniprot.org/uniprot/F1M8G6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1101, "end_pos": 1103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1121, "end_pos": 1123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1195, "end_pos": 1197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1429, "end_pos": 1431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1510, "end_pos": 1512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1773, "end_pos": 1775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1810, "end_pos": 1812, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1862, "end_pos": 1864, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2031, "end_pos": 2033, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2275, "end_pos": 2277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2298, "end_pos": 2300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2480, "end_pos": 2482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2485, "end_pos": 2487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2509, "end_pos": 2511, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2731, "end_pos": 2733, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2740, "end_pos": 2742, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2770, "end_pos": 2772, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2983, "end_pos": 2985, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3090, "end_pos": 3092, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 712, "end_pos": 714, "annotation": "n_glycosylation_sequon" }, { "start_pos": 727, "end_pos": 729, "annotation": "n_glycosylation_sequon" }, { "start_pos": 752, "end_pos": 754, "annotation": "n_glycosylation_sequon" }, { "start_pos": 886, "end_pos": 888, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22508", "name": "", "equation": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q673L6-1", "Q5RKI3-1", "O54747-1", "O89042-1", "P06766-1", "Q9QYV8-1", "D3Z8X4-1", "E9PT58-1", "D4A628-1", "F1M8G6-1", "A0A0G2K4L7-1", "F7F6Z7-1", "P28340-1", "Q07864-1", "P06746-1", "Q9UGP5-1", "P54098-1", "Q9NP87-1", "P09884-1", "Q7Z5Q5-1", "O75417-1", "O00370-1", "Q9WJR5-1", "Q9UBT6-1", "O60673-1", "Q9UNA4-1", "Q9Y253-1", "P63135-1", "P10266-1", "P63132-1", "P63133-1", "P63136-1", "Q9UQG0-1", "Q9QC07-1", "P63128-1", "Q9BXR3-1", "P04053-1", "O14746-1", "P10400-1", "P11369-1", "P52431-1", "Q7TQ07-1", "Q9JIW4-1", "P54099-1", "Q8K409-1", "P33609-1", "Q8CGS6-1", "Q9WVF7-1", "Q9QXE2-1", "Q61493-1", "O70372-1", "P09838-2", "Q6R3M4-1", "Q9JJN0-1", "Q9QUG2-1", "P13382-1", "P14284-1", "P15436-1", "P15801-1", "P21951-1", "P25384-1", "P25615-1", "P46957-1", "Q04049-1", "Q06163-1", "A0A0B7P3V8-1", "O13527-1", "O13535-1", "P0C2I2-1", "P0C2I3-1", "P0C2I5-1", "P0C2I6-1", "P0C2I9-1", "P0C2J0-1", "P0C2J1-1", "P0C2J3-1", "P0C2J7-1", "P0CX63-1", "P0CX64-1", "Q99231-1", "P39985-1", "P47024-1", "P47098-1", "P47100-1", "Q12472-1", "Q03434-1", "Q03494-1", "Q03612-1", "Q03619-1", "Q03855-1", "Q04214-1", "Q04670-1", "Q04711-1", "Q07791-1", "Q07793-1", "Q12088-1", "Q12112-1", "Q12113-1", "Q12141-1", "Q12193-1", "Q12269-1", "Q12273-1", "Q12316-1", "Q12414-1", "Q12490-1", "Q12491-1", "Q12501-1", "Q7LHG5-1", "Q92393-1", "Q99315-1", "Q99337-1", "Q55AZ3-1", "Q1ZXF2-1", "Q54B44-1", "Q86KS9-1", "Q54N97-1", "Q54RD4-1", "Q54SV8-1", "Q9GSR1-1", "Q9VHV1-1", "Q9VNX1-1", "Q9VCN1-1", "P26019-1", "P54358-1", "Q27607-1", "O18475-1" ], "evidence": [ { "id": "22508", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22508" } ] }, { "id": "R-RNO-110311", "name": "POLZ extends translesion synthesis", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1M8G6-1", "A0A8I5ZJ91-1" ], "evidence": [ { "id": "R-RNO-110311", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-110311" } ] }, { "id": "R-RNO-110322", "name": "Formation of Pol zeta complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1M8G6-1" ], "evidence": [ { "id": "R-RNO-110322", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-110322" } ] }, { "id": "R-RNO-5652151", "name": "REV1 recruits POLZ to (AP:Cyt)-DNA Template", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1M8G6-1", "A0A8I5ZJ91-1" ], "evidence": [ { "id": "R-RNO-5652151", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5652151" } ] }, { "id": "R-RNO-5655835", "name": "POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1M8G6-1", "A0A8I5ZJ91-1" ], "evidence": [ { "id": "R-RNO-5655835", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5655835" } ] }, { "id": "R-RNO-5655892", "name": "POLK incorporates dNMP opposite to damaged DNA base", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1M8G6-1", "A0A8I5ZJ91-1" ], "evidence": [ { "id": "R-RNO-5655892", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5655892" } ] }, { "id": "R-RNO-5655965", "name": "POLK and POLZ cooperate in elongation of mispaired primer termini", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [ "R-RNO-3006726" ], "enzyme_list": [ "F1M8G6-1", "A0A8I5ZJ91-1" ], "evidence": [ { "id": "R-RNO-5655965", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5655965" } ] }, { "id": "R-RNO-5656105", "name": "POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1M8G6-1", "A0A8I5ZJ91-1" ], "evidence": [ { "id": "R-RNO-5656105", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5656105" } ] }, { "id": "R-RNO-5656148", "name": "POLI incorporates dNMP opposite to damaged DNA base", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1M8G6-1", "A0A8I5ZJ91-1" ], "evidence": [ { "id": "R-RNO-5656148", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5656148" } ] }, { "id": "R-RNO-5656158", "name": "POLZ elongates POLI-incorporated dNMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1M8G6-1", "A0A8I5ZJ91-1" ], "evidence": [ { "id": "R-RNO-5656158", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5656158" } ] } ], "reaction_participants": [ { "participant_id": "R-RNO-3006726", "participant_name": "Rev1 [nucleoplasm]", "crossref": [ { "id": "D3ZRU9", "database": "UniProt", "url": "" }, { "id": "ENSRNOG00000018623", "database": "Ensembl", "url": "" }, { "id": "ENSRNOT00000067197", "database": "Ensembl", "url": "" }, { "id": "ENSRNOP00000059807", "database": "Ensembl", "url": "" }, { "id": "1306715", "database": "RGD", "url": "" }, { "id": "XP_006244881.1", "database": "RefSeq", "url": "" }, { "id": "XP_006244882.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A0B7P3V8", "gene_name": "TY4B-P", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "A0A0B7P3V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B7P3V8" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "A0A0B7P3V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B7P3V8" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "A0A0B7P3V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B7P3V8" } ] }, { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "A0A0B7P3V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0B7P3V8" } ] } ] }, { "uniprot_ac": "A0A0G2K4L7", "gene_name": "Polk", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "A0A0G2K4L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K4L7" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A0G2K4L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A0G2K4L7" } ] } ] }, { "uniprot_ac": "A0A8I5ZJ91", "gene_name": "Rev1", "activity": [ { "ec_number": "2.7.7.-", "activity": "", "evidence": [ { "id": "A0A8I5ZJ91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A8I5ZJ91" } ] } ] }, { "uniprot_ac": "D3Z8X4", "gene_name": "Pole", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "D3Z8X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z8X4" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "D3Z8X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z8X4" } ] } ] }, { "uniprot_ac": "D4A628", "gene_name": "Polq", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "D4A628", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A628" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "D4A628", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D4A628" } ] } ] }, { "uniprot_ac": "E9PT58", "gene_name": "Dntt", "activity": [ { "ec_number": "2.7.7.31", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "E9PT58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PT58" } ] }, { "ec_number": "2.7.7.31", "activity": "", "evidence": [ { "id": "E9PT58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/E9PT58" } ] } ] }, { "uniprot_ac": "F1M8G6", "gene_name": "Rev3l", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "F1M8G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M8G6" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "F1M8G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F1M8G6" } ] } ] }, { "uniprot_ac": "F7F6Z7", "gene_name": "Polm", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "F7F6Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F7F6Z7" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "F7F6Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/F7F6Z7" } ] } ] }, { "uniprot_ac": "O00370", "gene_name": "", "activity": [ { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "O00370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00370" } ] }, { "ec_number": "3.1.21.-", "activity": "", "evidence": [ { "id": "O00370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O00370" } ] } ] }, { "uniprot_ac": "O13527", "gene_name": "TY1B-A", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "O13527", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O13527" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "O13527", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O13527" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "O13527", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O13527" } ] } ] }, { "uniprot_ac": "O13535", "gene_name": "TY1B-H", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "O13535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O13535" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "O13535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O13535" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "O13535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O13535" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "O13535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O13535" } ] } ] }, { "uniprot_ac": "O14746", "gene_name": "TERT", "activity": [ { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "O14746", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14746" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "O14746", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O14746" } ] } ] }, { "uniprot_ac": "O18475", "gene_name": "PolQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "O18475", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O18475" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "O18475", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O18475" } ] } ] }, { "uniprot_ac": "O54747", "gene_name": "Pold1", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "O54747", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54747" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "O54747", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54747" } ] }, { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "O54747", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54747" } ] } ] }, { "uniprot_ac": "O60673", "gene_name": "REV3L", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "O60673", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60673" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "O60673", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O60673" } ] } ] }, { "uniprot_ac": "O70372", "gene_name": "Tert", "activity": [ { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "O70372", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70372" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "O70372", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70372" } ] } ] }, { "uniprot_ac": "O75417", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "O75417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75417" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "O75417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O75417" } ] } ] }, { "uniprot_ac": "O89042", "gene_name": "Pola1", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "O89042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O89042" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "O89042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O89042" } ] } ] }, { "uniprot_ac": "P04053", "gene_name": "DNTT", "activity": [ { "ec_number": "2.7.7.31", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P04053", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04053" } ] }, { "ec_number": "2.7.7.31", "activity": "", "evidence": [ { "id": "P04053", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P04053" } ] } ] }, { "uniprot_ac": "P06746", "gene_name": "POLB", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P06746", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06746" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P06746", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06746" } ] }, { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "P06746", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06746" } ] }, { "ec_number": "4.2.99.-", "activity": "", "evidence": [ { "id": "P06746", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06746" } ] } ] }, { "uniprot_ac": "P06766", "gene_name": "Polb", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P06766", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06766" } ] }, { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "P06766", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06766" } ] }, { "ec_number": "4.2.99.-", "activity": "", "evidence": [ { "id": "P06766", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06766" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P06766", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06766" } ] } ] }, { "uniprot_ac": "P09838", "gene_name": "Dntt", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P09838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09838" } ] }, { "ec_number": "2.7.7.31", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P09838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09838" } ] }, { "ec_number": "2.7.7.31", "activity": "", "evidence": [ { "id": "P09838", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09838" } ] } ] }, { "uniprot_ac": "P09884", "gene_name": "POLA1", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P09884", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09884" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P09884", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P09884" } ] } ] }, { "uniprot_ac": "P0C2I2", "gene_name": "TY1B-DR5", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I2" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P0C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I2" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I2" } ] }, { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "P0C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I2" } ] } ] }, { "uniprot_ac": "P0C2I3", "gene_name": "TY1B-DR6", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "P0C2I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I3" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I3" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P0C2I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I3" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I3" } ] } ] }, { "uniprot_ac": "P0C2I5", "gene_name": "TY1B-LR2", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "P0C2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I5" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I5" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P0C2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I5" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I5" } ] } ] }, { "uniprot_ac": "P0C2I6", "gene_name": "TY1B-LR3", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "P0C2I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I6" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I6" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P0C2I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I6" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I6" } ] } ] }, { "uniprot_ac": "P0C2I9", "gene_name": "TY1B-PR1", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "P0C2I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I9" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I9" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P0C2I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I9" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2I9" } ] } ] }, { "uniprot_ac": "P0C2J0", "gene_name": "TY1B-PR2", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "P0C2J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2J0" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2J0" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P0C2J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2J0" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2J0" } ] } ] }, { "uniprot_ac": "P0C2J1", "gene_name": "TY1B-PR3", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "P0C2J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2J1" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2J1" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P0C2J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2J1" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2J1" } ] } ] }, { "uniprot_ac": "P0C2J3", "gene_name": "TY2B-LR1", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2J3" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P0C2J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2J3" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2J3" } ] }, { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "P0C2J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2J3" } ] } ] }, { "uniprot_ac": "P0C2J7", "gene_name": "TY4B-H", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2J7" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P0C2J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2J7" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0C2J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2J7" } ] }, { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "P0C2J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0C2J7" } ] } ] }, { "uniprot_ac": "P0CX63", "gene_name": "TY2B-F", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0CX63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX63" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P0CX63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX63" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0CX63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX63" } ] }, { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "P0CX63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX63" } ] } ] }, { "uniprot_ac": "P0CX64", "gene_name": "TY2B-GR2", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0CX64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX64" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P0CX64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX64" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P0CX64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX64" } ] }, { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "P0CX64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P0CX64" } ] } ] }, { "uniprot_ac": "P10266", "gene_name": "ERVK-10", "activity": [ { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P10266", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10266" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P10266", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10266" } ] }, { "ec_number": "3.4.23.50", "activity": "Processing at the authentic HIV-1 PR recognition site and release of the mature p17 matrix and the p24 capsid protein, as a result of the cleavage of the -SQNY-|-PIVQ- cleavage site.", "evidence": [ { "id": "P10266", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10266" } ] } ] }, { "uniprot_ac": "P10400", "gene_name": "Pol", "activity": [ { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P10400", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P10400" } ] } ] }, { "uniprot_ac": "P11369", "gene_name": "Pol", "activity": [ { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P11369", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11369" } ] }, { "ec_number": "3.1.21.-", "activity": "", "evidence": [ { "id": "P11369", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P11369" } ] } ] }, { "uniprot_ac": "P13382", "gene_name": "POL1", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P13382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13382" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P13382", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P13382" } ] } ] }, { "uniprot_ac": "P14284", "gene_name": "REV3", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P14284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14284" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P14284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P14284" } ] } ] }, { "uniprot_ac": "P15436", "gene_name": "POL3", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P15436", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15436" } ] }, { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P15436", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15436" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P15436", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15436" } ] } ] }, { "uniprot_ac": "P15801", "gene_name": "MIP1", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P15801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15801" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P15801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P15801" } ] } ] }, { "uniprot_ac": "P21951", "gene_name": "POL2", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P21951", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21951" } ] }, { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P21951", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21951" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P21951", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P21951" } ] } ] }, { "uniprot_ac": "P25384", "gene_name": "TY2B-C", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P25384", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25384" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P25384", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25384" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P25384", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25384" } ] }, { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "P25384", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25384" } ] } ] }, { "uniprot_ac": "P25615", "gene_name": "POL4", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P25615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25615" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P25615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P25615" } ] } ] }, { "uniprot_ac": "P26019", "gene_name": "PolA1", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P26019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26019" } ] }, { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P26019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26019" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P26019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P26019" } ] } ] }, { "uniprot_ac": "P28340", "gene_name": "POLD1", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P28340", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28340" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P28340", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28340" } ] }, { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P28340", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P28340" } ] } ] }, { "uniprot_ac": "P33609", "gene_name": "Pola1", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P33609", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33609" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P33609", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P33609" } ] } ] }, { "uniprot_ac": "P39985", "gene_name": "POL5", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P39985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39985" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P39985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P39985" } ] } ] }, { "uniprot_ac": "P46957", "gene_name": "POL31", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P46957", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P46957" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P46957", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P46957" } ] } ] }, { "uniprot_ac": "P47024", "gene_name": "TY4B-J", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P47024", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47024" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P47024", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47024" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P47024", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47024" } ] }, { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "P47024", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47024" } ] } ] }, { "uniprot_ac": "P47098", "gene_name": "TY1B-JR1", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "P47098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47098" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P47098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47098" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P47098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47098" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P47098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47098" } ] } ] }, { "uniprot_ac": "P47100", "gene_name": "TY1B-JR2", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "P47100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47100" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P47100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47100" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P47100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47100" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P47100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P47100" } ] } ] }, { "uniprot_ac": "P52431", "gene_name": "Pold1", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P52431", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52431" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P52431", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52431" } ] }, { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52431", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P52431" } ] } ] }, { "uniprot_ac": "P54098", "gene_name": "POLG", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P54098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54098" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P54098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54098" } ] } ] }, { "uniprot_ac": "P54099", "gene_name": "Polg", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P54099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54099" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P54099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54099" } ] } ] }, { "uniprot_ac": "P54358", "gene_name": "PolD1", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P54358", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54358" } ] }, { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P54358", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54358" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "P54358", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P54358" } ] } ] }, { "uniprot_ac": "P63128", "gene_name": "ERVK-9", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P63128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63128" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P63128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63128" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P63128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63128" } ] }, { "ec_number": "3.4.23.50", "activity": "Processing at the authentic HIV-1 PR recognition site and release of the mature p17 matrix and the p24 capsid protein, as a result of the cleavage of the -SQNY-|-PIVQ- cleavage site.", "evidence": [ { "id": "P63128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63128" } ] } ] }, { "uniprot_ac": "P63132", "gene_name": "HERVK_113", "activity": [ { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P63132", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63132" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P63132", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63132" } ] } ] }, { "uniprot_ac": "P63133", "gene_name": "ERVK-8", "activity": [ { "ec_number": "3.4.23.50", "activity": "Processing at the authentic HIV-1 PR recognition site and release of the mature p17 matrix and the p24 capsid protein, as a result of the cleavage of the -SQNY-|-PIVQ- cleavage site.", "evidence": [ { "id": "P63133", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63133" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P63133", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63133" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P63133", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63133" } ] } ] }, { "uniprot_ac": "P63135", "gene_name": "ERVK-7", "activity": [ { "ec_number": "3.4.23.50", "activity": "Processing at the authentic HIV-1 PR recognition site and release of the mature p17 matrix and the p24 capsid protein, as a result of the cleavage of the -SQNY-|-PIVQ- cleavage site.", "evidence": [ { "id": "P63135", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63135" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P63135", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63135" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P63135", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63135" } ] } ] }, { "uniprot_ac": "P63136", "gene_name": "ERVK-25", "activity": [ { "ec_number": "3.4.23.50", "activity": "Processing at the authentic HIV-1 PR recognition site and release of the mature p17 matrix and the p24 capsid protein, as a result of the cleavage of the -SQNY-|-PIVQ- cleavage site.", "evidence": [ { "id": "P63136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63136" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "P63136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63136" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "P63136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63136" } ] } ] }, { "uniprot_ac": "Q03434", "gene_name": "TY1B-ML2", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q03434", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03434" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q03434", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03434" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q03434", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03434" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q03434", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03434" } ] } ] }, { "uniprot_ac": "Q03494", "gene_name": "TY2B-DR2", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q03494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03494" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q03494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03494" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q03494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03494" } ] }, { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q03494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03494" } ] } ] }, { "uniprot_ac": "Q03612", "gene_name": "TY1B-ER1", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q03612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03612" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q03612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03612" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q03612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03612" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q03612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03612" } ] } ] }, { "uniprot_ac": "Q03619", "gene_name": "TY1B-ER2", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q03619", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03619" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q03619", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03619" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q03619", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03619" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q03619", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03619" } ] } ] }, { "uniprot_ac": "Q03855", "gene_name": "TY1B-DR1", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q03855", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03855" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q03855", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03855" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q03855", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03855" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q03855", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q03855" } ] } ] }, { "uniprot_ac": "Q04049", "gene_name": "RAD30", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q04049", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04049" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "Q04049", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04049" } ] } ] }, { "uniprot_ac": "Q04214", "gene_name": "TY1B-MR1", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q04214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04214" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q04214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04214" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q04214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04214" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q04214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04214" } ] } ] }, { "uniprot_ac": "Q04670", "gene_name": "TY1B-MR2", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q04670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04670" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q04670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04670" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q04670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04670" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q04670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04670" } ] } ] }, { "uniprot_ac": "Q04711", "gene_name": "TY1B-ML1", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q04711", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04711" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q04711", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04711" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q04711", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04711" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q04711", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q04711" } ] } ] }, { "uniprot_ac": "Q06163", "gene_name": "EST2", "activity": [ { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q06163", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06163" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "Q06163", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q06163" } ] } ] }, { "uniprot_ac": "Q07791", "gene_name": "TY2B-DR3", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q07791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07791" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q07791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07791" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q07791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07791" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q07791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07791" } ] } ] }, { "uniprot_ac": "Q07793", "gene_name": "TY1B-DR4", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q07793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07793" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q07793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07793" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q07793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07793" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q07793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07793" } ] } ] }, { "uniprot_ac": "Q07864", "gene_name": "POLE", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q07864", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07864" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "Q07864", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07864" } ] }, { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q07864", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q07864" } ] } ] }, { "uniprot_ac": "Q12088", "gene_name": "TY1B-LR1", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q12088", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12088" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12088", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12088" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q12088", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12088" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12088", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12088" } ] } ] }, { "uniprot_ac": "Q12112", "gene_name": "TY1B-NL1", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q12112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12112" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12112" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q12112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12112" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12112", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12112" } ] } ] }, { "uniprot_ac": "Q12113", "gene_name": "TY2B-OR1", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12113", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12113" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q12113", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12113" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12113", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12113" } ] }, { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q12113", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12113" } ] } ] }, { "uniprot_ac": "Q12141", "gene_name": "TY1B-GR1", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q12141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12141" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12141" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q12141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12141" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12141" } ] } ] }, { "uniprot_ac": "Q12193", "gene_name": "TY1B-BR", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q12193", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12193" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12193", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12193" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q12193", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12193" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12193", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12193" } ] } ] }, { "uniprot_ac": "Q12269", "gene_name": "TY1B-GR2", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q12269", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12269" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12269", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12269" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q12269", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12269" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12269", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12269" } ] } ] }, { "uniprot_ac": "Q12273", "gene_name": "TY1B-OL", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q12273", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12273" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12273", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12273" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q12273", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12273" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12273", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12273" } ] } ] }, { "uniprot_ac": "Q12316", "gene_name": "TY1B-GR3", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q12316", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12316" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12316", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12316" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q12316", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12316" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12316", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12316" } ] } ] }, { "uniprot_ac": "Q12414", "gene_name": "TY1B-PL", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q12414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12414" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12414" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q12414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12414" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12414" } ] } ] }, { "uniprot_ac": "Q12472", "gene_name": "TY2B-DR1", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12472" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q12472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12472" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12472" } ] }, { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q12472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12472" } ] } ] }, { "uniprot_ac": "Q12490", "gene_name": "TY1B-BL", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q12490", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12490" } ] }, { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12490", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12490" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q12490", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12490" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12490", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12490" } ] } ] }, { "uniprot_ac": "Q12491", "gene_name": "TY2B-B", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12491" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q12491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12491" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12491" } ] }, { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q12491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12491" } ] } ] }, { "uniprot_ac": "Q12501", "gene_name": "TY2B-OR2", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12501", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12501" } ] }, { "ec_number": "3.1.26.4", "activity": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "Q12501", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12501" } ] }, { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q12501", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12501" } ] }, { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "Q12501", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q12501" } ] } ] }, { "uniprot_ac": "Q1ZXF2", "gene_name": "polB", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q1ZXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXF2" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "Q1ZXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q1ZXF2" } ] } ] }, { "uniprot_ac": "Q27607", "gene_name": "PolG1", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q27607", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q27607" } ] }, { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q27607", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q27607" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "Q27607", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q27607" } ] } ] }, { "uniprot_ac": "Q54B44", "gene_name": "", "activity": [ { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q54B44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54B44" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "Q54B44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54B44" } ] } ] }, { "uniprot_ac": "Q54N97", "gene_name": "pold1", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q54N97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54N97" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "Q54N97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54N97" } ] } ] }, { "uniprot_ac": "Q54RD4", "gene_name": "pole", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q54RD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RD4" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "Q54RD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54RD4" } ] } ] }, { "uniprot_ac": "Q54SV8", "gene_name": "pola1", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q54SV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54SV8" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "Q54SV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q54SV8" } ] } ] }, { "uniprot_ac": "Q55AZ3", "gene_name": "polZ", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q55AZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55AZ3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "Q55AZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q55AZ3" } ] } ] }, { "uniprot_ac": "Q5RKI3", "gene_name": "Poll", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q5RKI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RKI3" } ] }, { "ec_number": "4.2.99.-", "activity": "", "evidence": [ { "id": "Q5RKI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RKI3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "Q5RKI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q5RKI3" } ] } ] }, { "uniprot_ac": "Q61493", "gene_name": "Rev3l", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q61493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61493" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "Q61493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61493" } ] } ] }, { "uniprot_ac": "Q673L6", "gene_name": "Tert", "activity": [ { "ec_number": "2.7.7.49", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q673L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q673L6" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "Q673L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q673L6" } ] } ] }, { "uniprot_ac": "Q6R3M4", "gene_name": "Poli", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q6R3M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6R3M4" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "Q6R3M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6R3M4" } ] } ] }, { "uniprot_ac": "Q7LHG5", "gene_name": "TY3B-I", "activity": [ { "ec_number": "2.7.7.7", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).", "evidence": [ { "id": "Q7LHG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q7LHG5" } ] }, { 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