{ "uniprot_canonical_ac": "F1M7G6-1", "uniprot_ac": "F1M7G6", "uniprot_id": "F1M7G6_RAT", "mass": { "chemical_mass": 44193.0, "monoisotopic_mass": 44193.0 }, "refseq": { "ac": "NP_001258382", "name": "homeobox protein GBX-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258382" }, "gene_names": [ { "name": "Gbx1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/F1M7G6", "id": "F1M7G6" }, { "name": "Gbx1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258382", "id": "NP_001258382" } ], "protein_names": [ { "name": "Gastrulation brain homeobox 1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "F1M7G6" }, { "name": "gastrulation brain homeo box 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258382", "id": "NP_001258382" }, { "name": "homeobox protein GBX-1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258382", "id": "NP_001258382" } ], "function": [ { "annotation": "Tgm2/Gh, Gbx1 and TGF-beta are involved in retinoic acid-induced transdifferentiation from epidermis to mucosal epithelium", "evidence": [ { "database": "RefSeq", "id": "NP_001258382", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258382" }, { "database": "PubMed", "id": "22252490", "url": "https://glygen.org/publication/PubMed/22252490" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1M7G6", "url": "https://www.uniprot.org/uniprot/F1M7G6" } ], "common_name": "Rat" } ], "gene": [ { "name": "Gbx1", "url": "https://www.uniprot.org/uniprot/F1M7G6", "locus": { "chromosome": "4", "start_pos": 10672486, "end_pos": 10645957, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000013369", "url": "https://www.ensembl.org/id/ENSRNOG00000013369" } ] } } ], "crossref": [ { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "246149", "url": "https://www.ncbi.nlm.nih.gov/gene/246149", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:246149", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:246149", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGPLSQK", "url": "https://omabrowser.org/oma/group/CGPLSQK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "728401at2759", "url": "http://www.orthodb.org/?query=728401at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24334:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24334:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "http://pfam.xfam.org/family/PF00046", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001258382", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258382", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "621864", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=621864", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "F1M7G6", "url": "https://www.uniprot.org/uniprot/F1M7G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1M7G6-1", "url": "https://www.uniprot.org/uniprot/F1M7G6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPEGDTPSPPARPLPPYERGSAAPEPHCAEPAPRRYLGPRARSEPCVSAPGARRGPGSAMQRAAGGGAPGGSGGSGGGPGTAFSIDSLIGPPPPRSGHLLYTGYPMFMPYRPLVLPQALAPAPLPAGLPPLAPLASFAGRLSNTFCAGLGQAVPSMVALTTALPSFAEPPDAYYGPPELAAAAAAAAASTVSRSNPEPPARRTDGALDADELLPAREKVTEPPPPPPPPPPHFSETFPSLPAEGKVYSSDEEKLEPPAGEPAGSEPEEEGSGGDSEDSFLDSSAGGPGALLGPKPKLKGSLGTGAEEGTPVATGVTTPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRIKAGNVSSRSGEPVRNPKIVVPIPVHVNRFAVRSQHQQMEQGARP", "length": 425, "header": "tr|F1M7G6-1|F1M7G6_RAT Isoform 1 of Gastrulation brain homeobox 1 OS=Rattus norvegicus OX=10116 GN=Gbx1 PE=4 SV=2 CANONICAL=F1M7G6-1" }, "isoforms": [ { "isoform_ac": "F1M7G6-1", "url": "", "sequence": { "sequence": "MSPEGDTPSPPARPLPPYERGSAAPEPHCAEPAPRRYLGPRARSEPCVSAPGARRGPGSAMQRAAGGGAPGGSGGSGGGPGTAFSIDSLIGPPPPRSGHLLYTGYPMFMPYRPLVLPQALAPAPLPAGLPPLAPLASFAGRLSNTFCAGLGQAVPSMVALTTALPSFAEPPDAYYGPPELAAAAAAAAASTVSRSNPEPPARRTDGALDADELLPAREKVTEPPPPPPPPPPHFSETFPSLPAEGKVYSSDEEKLEPPAGEPAGSEPEEEGSGGDSEDSFLDSSAGGPGALLGPKPKLKGSLGTGAEEGTPVATGVTTPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRIKAGNVSSRSGEPVRNPKIVVPIPVHVNRFAVRSQHQQMEQGARP", "length": 425, "header": "tr|F1M7G6-1|F1M7G6_RAT Isoform 1 of Gastrulation brain homeobox 1 OS=Rattus norvegicus OX=10116 GN=Gbx1 PE=4 SV=2 CANONICAL=F1M7G6-1" }, "locus": { "chromosome": "4", "start_pos": 10672316, "end_pos": 10646343, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000017854.7", "url": "https://www.ensembl.org/id/ENSRNOT00000017854.7" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000017854.5", "url": "https://www.ensembl.org/id/ENSRNOP00000017854.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Tgm2/Gh, Gbx1 and TGF-beta are involved in retinoic acid-induced transdifferentiation from epidermis to mucosal epithelium.", "journal": "The International journal of developmental biology", "date": "2011", "authors": "Obinata A, Osakabe K, Yamaguchi M, Morimoto R, Akimoto Y", "evidence": [ { "database": "RefSeq", "id": "NP_001258382", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258382" } ], "reference": [ { "type": "PubMed", "id": "22252490", "url": "https://glygen.org/publication/PubMed/22252490" } ] } ], "pathway": [ { "id": "rno:246149", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:246149", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P82976-1", "protein_name": "Homeobox protein GBX-1", "gene_name": "Gbx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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