{ "uniprot_canonical_ac": "F1LU78-1", "uniprot_ac": "F1LU78", "uniprot_id": "F1LU78_RAT", "mass": { "chemical_mass": 127584.0, "monoisotopic_mass": 127584.0 }, "refseq": { "ac": "NP_001100312", "name": "sentrin-specific protease 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100312" }, "gene_names": [ { "name": "Senp6", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/F1LU78", "id": "F1LU78" }, { "name": "Senp6", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100312", "id": "NP_001100312" } ], "protein_names": [ { "name": "SUMO specific peptidase 6", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "F1LU78" }, { "name": "SUMO/sentrin specific protease 6; SUMO/sentrin specific peptidase 6; Sumo1/sentrin/SMT3 specific peptidase 6; SUMO1/sentrin specific peptidase 6", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100312", "id": "NP_001100312" }, { "name": "sentrin-specific protease 6 isoform X1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006243498", "id": "XP_006243498" }, { "name": "sentrin-specific protease 6", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100312", "id": "NP_001100312" } ], "function": [ { "annotation": "Our data suggest that ethanol exposure during adolescence induces the microglia-mediated neuroinflammation via TLR4 activation, and SENP6 plays an essential role in dampening NF-kappaB activation and neuroinflammation. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001100312", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100312" }, { "database": "PubMed", "id": "31781182", "url": "https://glygen.org/publication/PubMed/31781182" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LU78", "url": "https://www.uniprot.org/uniprot/F1LU78" } ], "common_name": "Rat" } ], "gene": [ { "name": "Senp6", "url": "https://www.uniprot.org/uniprot/F1LU78", "locus": { "chromosome": "8", "start_pos": 81067170, "end_pos": 80989052, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000024336", "url": "https://www.ensembl.org/id/ENSRNOG00000024336" } ] } } ], "crossref": [ { "id": "ENSRNOG00000024336", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000024336", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "300860", "url": "https://www.ncbi.nlm.nih.gov/gene/300860", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003653", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003653", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:300860", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:300860", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CSVKKIN", "url": "https://omabrowser.org/oma/group/CSVKKIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "1068193at2759", "url": "http://www.orthodb.org/?query=1068193at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46896", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46896", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46896:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46896:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02902", "url": "http://pfam.xfam.org/family/PF02902", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001100312", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100312", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1304565", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1304565", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A8I5ZW72", "url": "https://www.uniprot.org/uniprot/A0A8I5ZW72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I5ZW72-1", "url": "https://www.uniprot.org/uniprot/A0A8I5ZW72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6A909", "url": "https://www.uniprot.org/uniprot/A0A8I6A909", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6A909-1", "url": "https://www.uniprot.org/uniprot/A0A8I6A909-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1LU78", "url": "https://www.uniprot.org/uniprot/F1LU78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1LU78-1", "url": "https://www.uniprot.org/uniprot/F1LU78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGKSGGSAGGVFLKALARSESKRDGGFKNNWSFDHEEESEGDADKDGANLLSVEDEDSETSKGKKLNRRSEIVATSSGDFILKTYVRRNKTDGFKTLKGNAIGLNMLSNNKKLSENTQATALCSGTVVHGRRFHHAHVQMPGIKTAAQSNQDRKERKEYPPHVHKAENNPVMLSHGQGGDHVMKKTEDSESYVEPEVKRKVQQKRHCSTYQLSPLSPASKKCLTHFEVSEQRECCPKCGKEKENQTRCQSCGIVFHNDLQRNCRQAVTLNESTGPLLRTSIHQNSGGQKSQNTGLTAKKFYGNSVDKIPIDILLTCDGSRHNYIQTNGKVILPGGKIPKITNPKERKTSVSDLNDPIILSSDDDDDDDRTKRRESTSPQPADSACSSPAPSTGKVEAALNANTCRAEQEPRSSPAESELNTVVIPRKARMKDQLGNSISTPLKRRKVNTHGALIPVTSLSCQDFGSVILNCRSIRVGTLFRLLVEPVIFSLELIKIRLDGPDSVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSLQLQMSKEDKVWNDCKGINRITSLEEQYIILIFQTGLDHQADVVFESIITDIGIRNNVCNFFAKIPFEEANSRLVACTRSYEESIKGNCVQKENKVKTVSFESKIQLRSKQELQFFDDEEEAGESHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLSEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNSETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVMQKPSRAEDSYVSSASEVDACSQNSAAKPVIKKMLHRKHCLAVTDSSAAQEDSEPCYRRNAYSVKCSMKKKNHAVHENEEPSNGESACQEISDRTESEHGLQDECLNSAHHPDALSKIRLNYGDQSAEGGKLLEDELIDFSEDQDDPDDSSDDGLLADENYNSEIGQWHLKPTVCKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILNFELPMNLVNWFPPPRMKTKREEIRNIILKLQEEQSKEKRLLRDTSSAETSLGEGAEQYASSVSE", "length": 1135, "header": "tr|F1LU78-1|F1LU78_RAT Isoform 1 of SUMO specific peptidase 6 OS=Rattus norvegicus OX=10116 GN=Senp6 PE=1 SV=2 CANONICAL=F1LU78-1" }, "isoforms": [ { "isoform_ac": "A0A8I5ZW72-1", "url": "", "sequence": { "sequence": "MAAGKSGGSAGGVFLKALARSESKRDGGFKNNWSFDHEEESEGDADKDGANLLSVEDEDSETSKGKKLNRRSEIVATSSGDFILKTYVRRNKTDGFKTLKGNAIGLNMLSNNKKLSENTQATALCSGTVVHGRRFHHAHVQMPGIKTAAQSNQDRKERKEYPPHVHKAENNPVMLSHGQGGDHVMKKTEDSESYVEPEVKRKVQQKRHCSTYQLSPLSPASKKCLTHFEVSEQRECCPKCGKEKENQTRCQSCGIVFHNDLQRNCRQAVTLNESTGPLLRTSIHQNSGGQKSQNTGLTAKKFYGNSVDKIPIDILLTCDGSRHNYIQTNGKVILPGGKIPKITNPKERKTSVSDLNDPIILSSDDDDDDDRTKRRESTSPQPADSACSSPAPSTGKVEAALNANTCRAEQEPRSSPAESELNTVVIPRKARMKDQLGNSISTPLKRRKVNTHGALIPVTSLSCQDFGSVILNCRSIRVGTLFRLLVEPVIVRPDSVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSLQLQMSKEDKVWNDCKGINRITSLEEQYIILIFQTGLDHQADVVFESIITDIGIRNNVCNFFAKIPFEEANSRLVACTRSYEESIKGNCVQKENKVKTVSFESKIQLRSKQELQFFDDEEEAGESHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLSEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNSETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVMQKPSRAEDSYVSSASEVDACSQNSAAKPVIKKMLHRKHCLAVTDSSAAQEDSEPCYRRNAYSVKCSMKKKNHAVHENEEPSNGESACQEISDRTESEHGLQDECLNSAHHPDALSKIRLNYGDQSAEGGKLLEDELIDFSEDQDDPDDSSDDGLLADENYNSEIGQWHLKPTVCKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILNFELPMNLVNWFPPPRMKTKREEIRNIILKLQEEQSKEKRLLRDTSSAETSLGEGAEQYASSVSE", "length": 1125, "header": "tr|A0A8I5ZW72-1|A0A8I5ZW72_RAT Computationally mapped isoform of SUMO specific peptidase 6 OS=Rattus norvegicus OX=10116 GN=Senp6 PE=1 SV=1 CANONICAL=F1LU78-1" }, "locus": { "chromosome": "8", "start_pos": 81066283, "end_pos": 80989274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000117397.1", "url": "https://www.ensembl.org/id/ENSRNOT00000117397.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000083920.1", "url": "https://www.ensembl.org/id/ENSRNOP00000083920.1" } ] } }, { "isoform_ac": "A0A8I6A909-1", "url": "", "sequence": { "sequence": "MAAGKSGGSAGGVFLKALARSESKRDGGFKNNWSFDHEEESEGDADKDGANLLSVEDEDSETSKGKKLNRRSEIVATSSGDFILKTYVRRNKTDGFKTLKGNAIGLNMLSNNKKLSENTQATALCSGTVVHGRRFHHAHVQMPGIKTAAQRKEYPPHVHKAENNPVMLSHGQGGDHVMKKTEDSESYVEPEVKRKVQQKRHCSTYQLSPLSPASKKCLTHFEVSEQRECCPKCGKEKENQTRCQSCGIVFHNDLQRNCRQAVTLNESTGPLLRTSIHQNSGGQKSQNTGLTAKKFYGNSVDKIPIDILLTCDGSRHNYIQTNGKVILPGGKIPKITNPKERKTSVSDLNDPIILSSDDDDDDDRTKRRESTSPQPADSACSSPAPSTGKVEAALNANTCRAEQEPRSSPAESELNTVVIPRKARMKDQLGNSISTPLKRRKVNTHGALIPVTSLSCQDFGSVILNCRSIRVGTLFRLLVEPVIFSLELIKIRLDGPDSVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSLQLQMSKEDKVWNDCKGINRITSLEEQYIILIFQTGLDHQADVVFESIITDIGIRNNVCNFFAKIPFEEANSRLVACTRSYEESIKGNCVQKENKVKTVSFESKIQLRSKQELQFFDDEEEAGESHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLSEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNSETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVMQKPSRAEDSYVSSASEVDACSQNSAAKPVIKKMLHRKHCLAVTDSSAAQEDSEPCYRRNAYSVKCSMKKKNHAVHENEEPSNGESACQEISDRTESEHGLQDECLNSAHHPDALSKIRLNYGDQSAEGGKLLEDELIDFSEDQDDPDDSSDDGLLADENYNSEIGQWHLKPTVCKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILNFELPMNLVNWFPPPRMKTKREEIRNIILKLQEEQSKEKRLLRDTSSAETSLGEGAEQYASSVSE", "length": 1128, "header": "tr|A0A8I6A909-1|A0A8I6A909_RAT Computationally mapped isoform of SUMO specific peptidase 6 OS=Rattus norvegicus OX=10116 GN=Senp6 PE=3 SV=1 CANONICAL=F1LU78-1" }, "locus": { "chromosome": "8", "start_pos": 81066283, "end_pos": 80989274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000112852.1", "url": "https://www.ensembl.org/id/ENSRNOT00000112852.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000088254.1", "url": "https://www.ensembl.org/id/ENSRNOP00000088254.1" } ] } }, { "isoform_ac": "F1LU78-1", "url": "", "sequence": { "sequence": "MAAGKSGGSAGGVFLKALARSESKRDGGFKNNWSFDHEEESEGDADKDGANLLSVEDEDSETSKGKKLNRRSEIVATSSGDFILKTYVRRNKTDGFKTLKGNAIGLNMLSNNKKLSENTQATALCSGTVVHGRRFHHAHVQMPGIKTAAQSNQDRKERKEYPPHVHKAENNPVMLSHGQGGDHVMKKTEDSESYVEPEVKRKVQQKRHCSTYQLSPLSPASKKCLTHFEVSEQRECCPKCGKEKENQTRCQSCGIVFHNDLQRNCRQAVTLNESTGPLLRTSIHQNSGGQKSQNTGLTAKKFYGNSVDKIPIDILLTCDGSRHNYIQTNGKVILPGGKIPKITNPKERKTSVSDLNDPIILSSDDDDDDDRTKRRESTSPQPADSACSSPAPSTGKVEAALNANTCRAEQEPRSSPAESELNTVVIPRKARMKDQLGNSISTPLKRRKVNTHGALIPVTSLSCQDFGSVILNCRSIRVGTLFRLLVEPVIFSLELIKIRLDGPDSVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSLQLQMSKEDKVWNDCKGINRITSLEEQYIILIFQTGLDHQADVVFESIITDIGIRNNVCNFFAKIPFEEANSRLVACTRSYEESIKGNCVQKENKVKTVSFESKIQLRSKQELQFFDDEEEAGESHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLSEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNSETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVMQKPSRAEDSYVSSASEVDACSQNSAAKPVIKKMLHRKHCLAVTDSSAAQEDSEPCYRRNAYSVKCSMKKKNHAVHENEEPSNGESACQEISDRTESEHGLQDECLNSAHHPDALSKIRLNYGDQSAEGGKLLEDELIDFSEDQDDPDDSSDDGLLADENYNSEIGQWHLKPTVCKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILNFELPMNLVNWFPPPRMKTKREEIRNIILKLQEEQSKEKRLLRDTSSAETSLGEGAEQYASSVSE", "length": 1135, "header": "tr|F1LU78-1|F1LU78_RAT Isoform 1 of SUMO specific peptidase 6 OS=Rattus norvegicus OX=10116 GN=Senp6 PE=1 SV=2 CANONICAL=F1LU78-1" }, "locus": { "chromosome": "8", "start_pos": 81066283, "end_pos": 80989274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000015741.7", "url": "https://www.ensembl.org/id/ENSRNOT00000015741.7" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000015741.6", "url": "https://www.ensembl.org/id/ENSRNOP00000015741.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nat. Commun.", "date": "2012", "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV", "evidence": [ { "database": "UniProtKB", "id": "F1LU78", "url": "https://www.uniprot.org/uniprot/F1LU78" } ], "reference": [ { "type": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] }, { "title": "Ethanol Exposure Induces Microglia Activation and Neuroinflammation through TLR4 Activation and SENP6 Modulation in the Adolescent Rat Hippocampus.", "journal": "Neural plasticity", "date": "2019", "authors": "Li Q, Liu D, Pan F, Ho CSH, Ho RCM", "evidence": [ { "database": "RefSeq", "id": "NP_001100312", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100312" } ], "reference": [ { "type": "PubMed", "id": "31781182", "url": "https://glygen.org/publication/PubMed/31781182" } ] } ], "pathway": [ { "id": "rno:300860", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:300860", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6P7W0-1", "protein_name": "Sentrin-specific protease 6", "gene_name": "Senp6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAGKSGGSAGALFLKALDRSESKRDGGFKNNWSFDHEEESEGDADKDGANLLSVEDEDSEISKGKKLNRRSEIVATSSGDFILKTYVRRSKTDGFKTLKGNPIGLNMLSNNKKLSESTAGTALCSGTVVHGRRFHHAHSQTPGIRTAAQRKEYPPYVHKAENSPVMLSHGQGGDHIMKKTEESESYVESEIKRKVQQKRHCSTYQLSPLSPASKKCLTHLEVSEQREYCPKCGKEKENQTKCQSCGIVFHNDLQRNCRQAVTLNEPTGPLLRTSIHQNSGGQKSQNTGLTAKKFYGNSVDKIPIDILVTCDDSRHNYIQTNGKVILPGGKIPKLTNPKERKISVSDLNDPIILSSDDDDDDDDRTKRRESTSPKPADSACSSPVPSTGKVEAALNADACRAEQEPRSSPAEPELNTIVIPRKARMKDQLGNSISTPLKRRKVNSHAAFIHPMSLSCQNFESVILNCRSIRVGTLFRLLVEPVIFSLESITIHLDGPESDPVDIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSMQLQMSKEDKVWNDCKGINRITSLEEQYIILIFQTGLDHQAEVVFESIITDIGIRNNVPNFFAKILFDEANSRLVACTRSYEESIKGNCAQKENKVKTVSFESKIQLRSKQELQFFDDDEEAGESHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLSEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNPETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVMQKTPSAEDSCVSSASEMGACSQNSAAKPVIKKMLNRKHCLAVTDSSAAQEESEPCYRRNAYSVKCSMKKKNHAINENEEPSNGESTCQDICDRTQSENGLRDECFSSVHHPDALSKIRLNYGDQSADGGKLLEDELIDFSEDQDDPDDSSDDGLLADENYSSEIGQWHLKPTVCKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPVLNFELPMNLMNWFPPPRMKTKREEIRNIILKLQESQSKDKKLLKDSLAETSLGDGAEQYASASGGSE", "length": 1132 }, "evidence": [ { "id": "45236240", "url": "http://www.informatics.jax.org/homology/45236240", "database": "MGI" } ], "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9GZR1-1", "protein_name": "Sentrin-specific protease 6", "gene_name": "SENP6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGKSGGSAGEITFLEALARSESKRDGGFKNNWSFDHEEESEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSENTQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDRKERKEYPPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDLQRNCRQAITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQTNGKVILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSACSSPAPSTGKVEAALNENTCRAERELRSIPEDSELNTVTLPRKARMKDQFGNSIINTPLKRRKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHDPVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLTNLEEQYIILIFQNGLDPPANMVFESIINEIGIKNNISNFFAKIPFEEANGRLVACTRTYEESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQEESDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIGQWHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLANWFPPPRMRTKREEIRNIILKLQEDQSKEKRKHKDTYSTEAPLGEGTEQYVNSISD", 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"" }, { "name": "protein desumoylation", "id": "GO:0016926", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016926", "evidence": [ { "database": "UniProtKB", "id": "F1LU78", "url": "https://www.uniprot.org/uniprot/F1LU78" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1LU78", "url": "https://www.uniprot.org/uniprot/F1LU78" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1LU78", "url": "https://www.uniprot.org/uniprot/F1LU78" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1LU78", "url": "https://www.uniprot.org/uniprot/F1LU78" } ], "pmid": "" }, { "name": "cytosol", "id": 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