{ "uniprot_canonical_ac": "F1LRS8-1", "uniprot_ac": "F1LRS8", "uniprot_id": "CD2AP_RAT", "mass": { "chemical_mass": 70491.0, "monoisotopic_mass": 70491.0 }, "refseq": {}, "gene_names": [ { "name": "Cd2ap", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/F1LRS8", "id": "F1LRS8" } ], "protein_names": [ { "name": "CD2-associated protein", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "F1LRS8" } ], "function": [ { "annotation": "Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton (By similarity). In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation (PubMed:18753381). May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell (By similarity). May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis. Plays a role in epithelial cell junctions formation (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "F1LRS8", "url": "https://www.uniprot.org/uniprot/F1LRS8#function" }, { "database": "UniProtKB", "id": "Q9Y5K6", "url": "https://www.uniprot.org/uniprot/Q9Y5K6#function" }, { "database": "UniProtKB", "id": "Q9JLQ0", "url": "https://www.uniprot.org/uniprot/Q9JLQ0#function" }, { "database": "PubMed", "id": "18753381", "url": "https://glygen.org/publication/PubMed/18753381" } ] } ], "disease": [ { "disease_id": "DOID:0112245", "recommended_name": { "id": "DOID:0112245", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0112245", "name": "focal segmental glomerulosclerosis 3", "description": "A focal segmental glomerulosclerosis that has_material_basis_in loss of function mutation in the CD2AP gene on chromosome 6p12.3." }, "synonyms": [ { "id": "DOID:0112245", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0112245", "name": "FSGS3", "description": "" }, { "id": "MONDO:0011917", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011917", "name": "focal segmental glomerulosclerosis 3, susceptibility to", "description": "Any focal segmental glomerulosclerosis in which the cause of the disease is a mutation in the CD2AP gene." }, { "id": "MONDO:0011917", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011917", "name": "CD2AP focal segmental glomerulosclerosis", "description": "" }, { "id": "MONDO:0011917", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011917", "name": "focal segmental glomerulosclerosis 3, susceptibility to", "description": "" }, { "id": "MONDO:0011917", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011917", "name": "focal segmental glomerulosclerosis caused by mutation in CD2AP", "description": "" }, { "id": "MONDO:0011917", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011917", "name": "glomerulosclerosis, focal segmental, 3", "description": "" }, { "id": "MONDO:0011917", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011917", "name": "FSGS3", "description": "" }, { "id": "MONDO:0011917", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011917", "name": "glomerulosclerosis, focal segmental, 3, susceptibility to", "description": "" }, { "id": "MONDO:0011917", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011917", "name": "susceptibility to focal segmental glomerulosclerosis 3", "description": "" }, { "id": "MIM:607832", "resource": "MIM", "url": "https://www.omim.org/entry/607832", "name": "Focal segmental glomerulosclerosis 3", "description": "Focal segmental glomerulosclerosis 3" } ], "evidence": [ { "id": "0112245", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0112245" } ] }, { "disease_id": "DOID:1184", "recommended_name": { "id": "DOID:1184", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability." }, "synonyms": [], "evidence": [ { "id": "1184", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ] }, { "disease_id": "DOID:1312", "recommended_name": { "id": "DOID:1312", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1312", "name": "focal segmental glomerulosclerosis", "description": "" }, "synonyms": [ { "id": "DOID:1312", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1312", "name": "FGS", "description": "" }, { "id": "DOID:1312", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1312", "name": "FSGS", "description": "" }, { "id": "DOID:1312", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1312", "name": "focal glomerular sclerosis", "description": "" }, { "id": "DOID:1312", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1312", "name": "focal glomerulosclerosis", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "focal segmental glomerulosclerosis 1", "description": "Any focal segmental glomerulosclerosis in which the cause of the disease is a mutation in the ACTN4 gene." }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "ACTN4 focal segmental glomerulosclerosis", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "FSGS1", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "familial idiopathic steroid-resistant nephrotic syndrome with focal segmental glomerulosclerosis", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "focal segmental glomerulosclerosis 1", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "focal segmental glomerulosclerosis caused by mutation in ACTN4", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "focal segmental glomerulosclerosis type 1", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "familial idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "glomerulosclerosis, focal segmental, 1", "description": "" }, { "id": "MIM:603278", "resource": "MIM", "url": "https://www.omim.org/entry/603278", "name": "Focal segmental glomerulosclerosis 1", "description": "Focal segmental glomerulosclerosis 1" } ], "evidence": [ { "id": "1312", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:1312" } ] }, { "disease_id": "DOID:680", "recommended_name": { "id": "DOID:680", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:680", "name": "tauopathy", "description": "A neurodegenerative disease that has_material_basis_in the pathological aggregation of tau protein in so-called neurofibrillary tangles (NFT) in the human brain." }, "synonyms": [], "evidence": [ { "id": "680", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:680" } ] }, { "disease_id": "DOID:783", "recommended_name": { "id": "DOID:783", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease." }, "synonyms": [ { "id": "DOID:783", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:783", "name": "end stage renal failure", "description": "" }, { "id": "DOID:783", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:783", "name": "end-stage kidney disease", "description": "" } ], "evidence": [ { "id": "783", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:783" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "F1LRS8", "url": "https://www.uniprot.org/uniprot/F1LRS8" } ], "common_name": "Rat" } ], "gene": [ { "name": "Cd2ap", "url": "https://www.uniprot.org/uniprot/F1LRS8", "locus": { "chromosome": "9", "start_pos": 18182199, "end_pos": 18086984, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000011987", "url": "https://www.ensembl.org/id/ENSRNOG00000011987" } ] } } ], "crossref": [ { "id": "ENSRNOG00000011987", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000011987", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12053", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12053", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12056", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12056", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "F1LRS8", "url": "https://www.ebi.ac.uk/intact/interactors/id:F1LRS8*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RSPGTIY", "url": "https://omabrowser.org/oma/group/RSPGTIY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "2972088at2759", "url": "http://www.orthodb.org/?query=2972088at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14167:SF77", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14167:SF77", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14167:SF92", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14167:SF92", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "http://pfam.xfam.org/family/PF00018", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF14604", "url": "http://pfam.xfam.org/family/PF14604", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_F1LRS8", "url": "http://purl.obolibrary.org/obo/PR_F1LRS8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "727803", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=727803", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A8I6A6A6", "url": "https://www.uniprot.org/uniprot/A0A8I6A6A6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6A6A6-1", "url": "https://www.uniprot.org/uniprot/A0A8I6A6A6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6GF65", "url": "https://www.uniprot.org/uniprot/A0A8I6GF65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6GF65-1", "url": "https://www.uniprot.org/uniprot/A0A8I6GF65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8L2Q7T7", "url": "https://www.uniprot.org/uniprot/A0A8L2Q7T7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8L2Q7T7-1", "url": "https://www.uniprot.org/uniprot/A0A8L2Q7T7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1LRS8", "url": "https://www.uniprot.org/uniprot/F1LRS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1LRS8-1", "url": "https://www.uniprot.org/uniprot/F1LRS8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRETEPKDDNLPIKRERPGNVASLVQRISTYGLPAGGIQPHPQTKAMKKKTKKRQCKVLFEYSPQNEDELELTVGDVIDVIEEVEEGWWSGTLNNKLGLFPSNFVKELESTDDGEMHDAQEESEVSLTGPTSPMPSPGNGSEPAPGSVTQPKKIRGVGFGDIFKEGSVKLRTRTSSSETEEKKSEKPLILQSLGSRTQNVEVTKPDIDGKIKAKEYCKTVFPYTGTNEDELTFREGEIIHLISKETGEAGWWKGELNGKEGVFPDNFAVQISELDKDFPKPKKPPPPAKGPAPKPDPLAGEKKTFPLKAEDRDEKSLLEQKPSKPAAPQVPPKKPTPPTKANNLLRSPGTMYPKRPEKPVPPPPPTAKINGEVSTISSKIDTEPLSKPKLDPEQLPVRPKSVDLDALVARNSKETDNVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTQSPEKTLKLPKDDDSGNIKPSEFKKDAGYSSKPSLSAPSSASKVNTAAFLSPLELKAKVEADDGKKSSLDELRAQIIELLCIVDALKKDHGKELEKLRRELEEEKAMRSNLEVEIAKLKKAVLLS", "length": 637, "header": "sp|F1LRS8-1|CD2AP_RAT Isoform 1 of CD2-associated protein OS=Rattus norvegicus OX=10116 GN=Cd2ap PE=1 SV=2 CANONICAL=F1LRS8-1" }, "isoforms": [ { "isoform_ac": "A0A8I6A6A6-1", "url": "", "sequence": { "sequence": "MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRETEPKDDNLPIKRERPGNVASLVQRISTYGLPAGGIQPHPQTKAMKKKTKKRQCKVLFEYSPQNEDELELTVGDVIDVIEEVEEGWWSGTLNNKLGLFPSNFVKELESTDDGEMHDAQEESEVSLTGPTSPMPSPGNGSEPAPGSVTQPKKIRGVGFGDIFKEGSVKLRTRTSSSETEEKKSEKPLILQSLGSRTQNVEVTKPDIDGKIKAKEYCKTVFPYTGTNEDELTFREGEIIHLISKETGEAGWWKGELNGKEGVFPDNFAVQISELDKDFPYSLSSPLPAPKPDPLAGEKKTFPLKAEDRDEKSLLEQKPSKPAAPQVPPKKPTPPTKANNLLRSPGTMYPKRPEKPVPPPPPTAKINGEVSTISSKIDTEPLSKPKLDPEQLPVRPKSVDLDALVARNSKETDNVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTQSPEKTLKLPKDDDSGNIKPSEFKKDAGYSSKPSLSAPSSASKVNTAAFLSPLELKAKVEADDGKKSSLDELRAQIIELLCIVDALKKDHGKELEKLRRELEEEKAMRSNLEVEIAKLKKAVLLS", "length": 633, "header": "tr|A0A8I6A6A6-1|CD2AP_RAT Computationally mapped isoform of CD2-associated protein OS=Rattus norvegicus OX=10116 GN=Cd2ap PE=1 SV=1 CANONICAL=F1LRS8-1" }, "locus": { "chromosome": "9", "start_pos": 18179179, "end_pos": 18087097, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000120136.1", "url": "https://www.ensembl.org/id/ENSRNOT00000120136.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000088324.1", "url": "https://www.ensembl.org/id/ENSRNOP00000088324.1" } ] } }, { "isoform_ac": "A0A8I6GF65-1", "url": "", "sequence": { "sequence": "METKKRQCKVLFEYSPQNEDELELTVGDVIDVIEEVEEGWWSGTLNNKLGLFPSNFVKELESTDDGEMHDAQEESEVSLTGPTSPMPSPGNGSEPAPGSVTQPKKIRGVGFGDIFKEGSVKLRTRTSSSETEEKKSEKPLILQSLGSRTQNVEVTKPDIDGKIKAKEYCKTVFPYTGTNEDELTFREGEIIHLISKETGEAGWWKGELNGKEGVFPDNFAVQISELDKDFPKPKKPPPPAKGPAPKPDPLAGEKKTFPLKAEDRDEKSLLEQKPSKPAAPQVPPKKPTPPTKANNLLRSPGTMYPKRPEKPVPPPPPTAKINGEVSTISSKIDTEPLSKPKLDPEQLPVRPKSVDLDALVARNSKETDNVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTQSPEKTLKLPKDDDSGNIKPSEFKKDAGYSSKPSLSAPSSASKVNTAAFLSPLELKAKVEADDGKKSSLDELRAQIIELLCIVDALKKDHGKELEKLRRELEEEKAMRSNLEVEIAKLKKAVLLS", "length": 532, "header": "tr|A0A8I6GF65-1|CD2AP_RAT Computationally mapped isoform of CD2-associated protein OS=Rattus norvegicus OX=10116 GN=Cd2ap PE=1 SV=1 CANONICAL=F1LRS8-1" }, "locus": { "chromosome": "9", "start_pos": 18179179, "end_pos": 18087097, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000107057.1", "url": "https://www.ensembl.org/id/ENSRNOT00000107057.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000086646.1", "url": "https://www.ensembl.org/id/ENSRNOP00000086646.1" } ] } }, { "isoform_ac": "A0A8L2Q7T7-1", "url": "", "sequence": { "sequence": "LVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRETEPKDDNLPIKRERPGNVASLVQRISTYGLPAGGIQPHPQTKAMKKKTKKRQCKVLFEYSPQNEDELELTVGDVIDVIEEVEEGWWSGTLNNKLGLFPSNFVKELESTDDGEMHDAQEESEVSLTGPTSPMPSPGNGSEPAPGSVTQPKKIRGVGFGDIFKEGSVKLRTRTSSSETEEKKSEKPLILQSLGSRTQNVEVTKPDIDGKIKAKEYCKTVFPYTGTNEDELTFREGEIIHLISKETGEAGWWKGELNGKEGVFPDNFAVQISELDKDFPKPKKPPPPAKGPAPKPDPLAGEKKTFPLKAEDRDEKSLLEQKPSKPAAPQVPPKKPTPPTKANNLLRSPGTMYPKRPEKPVPPPPPTAKINGEVSTISSKIDTEPLSKPKLDPEQLPVRPKSVDLDALVARNSKETDNVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTQSPEKTLKLPKDDDSGNIKPSEFKKDAGYSSKPSLSAPSSASKVNTAAFLSPLELKAKVEADDGKKSSLDELRAQIIELLCIVDALKKDHGKELEKLRRELEEEKAMRSNLEVEIAKLKKAVLLS", "length": 637, "header": "tr|A0A8L2Q7T7-1|CD2AP_RAT Computationally mapped isoform of CD2-associated protein OS=Rattus norvegicus OX=10116 GN=Cd2ap PE=1 SV=1 CANONICAL=F1LRS8-1" }, "locus": { "chromosome": "9", "start_pos": 18179179, "end_pos": 18117661, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000016291.4", "url": "https://www.ensembl.org/id/ENSRNOT00000016291.4" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000016291.4", "url": "https://www.ensembl.org/id/ENSRNOP00000016291.4" } ] } }, { "isoform_ac": "F1LRS8-1", "url": "", "sequence": { "sequence": "MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRETEPKDDNLPIKRERPGNVASLVQRISTYGLPAGGIQPHPQTKAMKKKTKKRQCKVLFEYSPQNEDELELTVGDVIDVIEEVEEGWWSGTLNNKLGLFPSNFVKELESTDDGEMHDAQEESEVSLTGPTSPMPSPGNGSEPAPGSVTQPKKIRGVGFGDIFKEGSVKLRTRTSSSETEEKKSEKPLILQSLGSRTQNVEVTKPDIDGKIKAKEYCKTVFPYTGTNEDELTFREGEIIHLISKETGEAGWWKGELNGKEGVFPDNFAVQISELDKDFPKPKKPPPPAKGPAPKPDPLAGEKKTFPLKAEDRDEKSLLEQKPSKPAAPQVPPKKPTPPTKANNLLRSPGTMYPKRPEKPVPPPPPTAKINGEVSTISSKIDTEPLSKPKLDPEQLPVRPKSVDLDALVARNSKETDNVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTQSPEKTLKLPKDDDSGNIKPSEFKKDAGYSSKPSLSAPSSASKVNTAAFLSPLELKAKVEADDGKKSSLDELRAQIIELLCIVDALKKDHGKELEKLRRELEEEKAMRSNLEVEIAKLKKAVLLS", "length": 637, "header": "sp|F1LRS8-1|CD2AP_RAT Isoform 1 of CD2-associated protein OS=Rattus norvegicus OX=10116 GN=Cd2ap PE=1 SV=2 CANONICAL=F1LRS8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 224, "end_pos": 224, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "F1LRS8", "url": "https://www.uniprot.org/uniprot/F1LRS8" } ], "site_lbl": "Ser224" }, { "start_pos": 458, "end_pos": 458, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "F1LRS8", "url": "https://www.uniprot.org/uniprot/F1LRS8" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "F1LRS8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/F1LRS8" } ], "site_lbl": "Ser458" }, { "start_pos": 469, "end_pos": 469, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": 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