{
    "uniprot_canonical_ac": "E9Q6E9-1",
    "uniprot_ac": "E9Q6E9",
    "uniprot_id": "SIMC1_MOUSE",
    "mass": {
        "chemical_mass": 146618.0,
        "monoisotopic_mass": 146618.0
    },
    "refseq": {
        "ac": "NP_795961",
        "name": "SUMO-interacting motif-containing protein 1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_795961"
    },
    "gene_names": [
        {
            "name": "Simc1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/E9Q6E9",
            "id": "E9Q6E9"
        },
        {
            "name": "4732471D19Rik",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_795961",
            "id": "NP_795961"
        },
        {
            "name": "4732471D19Rik",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/E9Q6E9",
            "id": "E9Q6E9"
        },
        {
            "name": "Pleiad",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/E9Q6E9",
            "id": "E9Q6E9"
        },
        {
            "name": "Simc1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_795961",
            "id": "NP_795961"
        }
    ],
    "protein_names": [
        {
            "name": "SUMO-interacting motif-containing protein 1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "E9Q6E9"
        },
        {
            "name": "Platform element for inhibition of autolytic degradation",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "E9Q6E9"
        },
        {
            "name": "SUMO-interacting motif-containing protein 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_795961",
            "id": "NP_795961"
        },
        {
            "name": "platform element for inhibition of autolytic degradation",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_795961",
            "id": "NP_795961"
        }
    ],
    "function": [
        {
            "annotation": "Inhibits the protease activity of CAPN3. May play a role in SMC5-SMC6 complex recruitment for viral restriction. Forms a complex with SLF2 and this complex is required to recruit SMC5-SMC6 complex to PML nuclear bodies and sites of viral replication.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "E9Q6E9",
                    "url": "https://www.uniprot.org/uniprot/E9Q6E9#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q8NDZ2",
                    "url": "https://www.uniprot.org/uniprot/Q8NDZ2#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "E9Q6E9",
                    "url": "https://www.uniprot.org/uniprot/E9Q6E9"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Simc1",
            "url": "https://www.uniprot.org/uniprot/E9Q6E9",
            "locus": {
                "chromosome": "13",
                "start_pos": 54699103,
                "end_pos": 54651592,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000043183",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000043183"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000043183",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000043183",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "319719",
            "url": "https://www.ncbi.nlm.nih.gov/gene/319719",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "mmu:319719",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:319719",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "2442599",
            "url": "http://www.informatics.jax.org/marker/MGI:2442599",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "VMQSPRD",
            "url": "https://omabrowser.org/oma/group/VMQSPRD/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5357586at2759",
            "url": "http://www.orthodb.org/?query=5357586at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23187",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23187",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23187:SF3",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23187:SF3",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_E9Q6E9",
            "url": "http://purl.obolibrary.org/obo/PR_E9Q6E9",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_795961",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_795961",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E0CX51",
            "url": "https://www.uniprot.org/uniprot/E0CX51",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E0CX51-1",
            "url": "https://www.uniprot.org/uniprot/E0CX51-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E0CY56",
            "url": "https://www.uniprot.org/uniprot/E0CY56",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E0CY56-1",
            "url": "https://www.uniprot.org/uniprot/E0CY56-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9PYI6",
            "url": "https://www.uniprot.org/uniprot/E9PYI6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9PYI6-1",
            "url": "https://www.uniprot.org/uniprot/E9PYI6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9Q6E9",
            "url": "https://www.uniprot.org/uniprot/E9Q6E9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9Q6E9-1",
            "url": "https://www.uniprot.org/uniprot/E9Q6E9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9Q6E9-2",
            "url": "https://www.uniprot.org/uniprot/E9Q6E9-2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MEDFIVISDDSGSESSAGTRSGRARRLRRALSRTPGALPRRTVDFIDLTRENRARTKDRNGLCVIDLTRNEEENRPIATLDLTLEPVASSQKEPTSLQTCTSLSGKEVMEAHEDRGSQPAAQRIINNDPVDLDLLEENLFEGSRPPTSISQDSVYPPEPNCSSITYKGDLSFLTSLQLSSDVSSFSSTSNQRASLPCPQQDVPCQSQGLLCPLQALSCPQTASPCPPRASSCPPQALSCPPQALSCPSQTLQCQLQALPQPPQEVPCSTQNVPCPQQNMPSTPQGLSWHPRHTLYPYQDTLGLPQDVPGRPQNMSYPQDVTQLQDMPWSLHDMPLSLQDVLQSLQDVPPLLGDVPPSPEVMQLPGYVTQTSRDVIQSPAGVTQSLGSMMQSPGSVTQSLRSVMQSSGSVTQSLRSVMQSSGSVTQSLRSVMQSSGSVMQSPGGVTQSLRSVTQSPGGVMQSPGGVMQSPRDVMQSPRDVMQSPRDVMQSPRGVTQSLGSMMQSPGGVMQSLRSVMQSSGGVTQSLRSVMQSPGGVMQSPGGVTQSPRGMIKSPGMMLSPGDVIQSLNSVPQSSRDRMQSAGHVPSASGDAIQSPGGMSPTSRDRMQSPGGVSLATEDSIQLPGGVPLSSDVIQSQGGVPLSSKDRMQSPGGVPPSSGDMIQSQGGVPQSLGDAIQSAGGVPQSSGDAIQSPGGVSLATGDSIQLPGGVPLSSGDVIQSQGGVPRSSRDRMQSPGGVPPSSGGVIQSPGGVSPASGDAIQSPGSVLPASGDAIQSAGGVLLASGDAIQSPRSVPQSPSGTLRSPGNMSESLGDTPNLSGDVSNSPQALLDLARDRPKSSPNDVQNRDTPMDISASSSSSCSANPQSRQSEFKLDKVPWLTITDSSARREKSLPQLANPGSAQIQGQIPQVGVYNRPCLHRLKYFLRPPVHHLFFQTLIPDKDTRESKGQKLEPIPHRRLRMVTNTIEENFPLGTVQFLMDFVSPQHYPPREIVAHIVQKILLSGSETVDVLKEAYMLLMKIQQLHPANAKTVEWDWKLLTYVMEEEGQTLPGRVLFLRYVVQTLEDDFQQILRRQRQHLQQSIANTVLSCDKQPHNVRDVIKWLVKAVTENELTPPQDETQTSPRTGVLKTSSDHLSPRPNQNKNTNQLIVCQLQRMLSIAVEVDRTPTCSSNKIAEMMFGFVLDIPERSQREMFFTTMESHLLRCKVLEIIFLHSCETPTRLPLSLAQTLYFLNNSTSLLKCQSDKTQWQTWDELVEHLQFLLSSYQHVLREHLRSSVIDRKDLIIKRIKPKPQQGDDITVLDVEKQIEAFRSRLVHILGEPLVPQLQDKVHLLKLLLFYAADLNPDTEPASEH",
        "length": 1354,
        "header": "sp|E9Q6E9-1|SIMC1_MOUSE Isoform 1 of SUMO-interacting motif-containing protein 1  OS=Mus musculus OX=10090 GN=Simc1 PE=1 SV=1 CANONICAL=E9Q6E9-1"
    },
    "isoforms": [
        {
            "isoform_ac": "E0CX51-1",
            "url": "",
            "sequence": {
                "sequence": "MEDFIVISDDSGSESSAGTRSGRARRLRRALSRTPGALPRRTVGQTLPGRVLFLRYVVQTLEDDFQQILRRQRQHLQQSIANTVLSCDKQPHNVRDVIKWLVKAVTENELTPPQDETQTSPRTGVLKTSSDHLSPRPNQNKNTNQL",
                "length": 146,
                "header": "tr|E0CX51-1|E0CX51_MOUSE Computationally mapped isoform of SUMO-interacting motifs containing 1  OS=Mus musculus OX=10090 GN=Simc1 PE=1 SV=1 CANONICAL=E9Q6E9-1"
            },
            "locus": {
                "chromosome": "13",
                "start_pos": 54687670,
                "end_pos": 54651689,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000159721.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000159721.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000124921.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000124921.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "E0CY56-1",
            "url": "",
            "sequence": {
                "sequence": "MEDFIVISDDSGSESSAGTRSGRARRLRRALSRTPGALPRRTVAASSQCQDSGVGLETAHLCHGGRGTNSAWTSSLSTLRSANPGR",
                "length": 86,
                "header": "tr|E0CY56-1|E0CY56_MOUSE Computationally mapped isoform of SUMO-interacting motifs containing 1  OS=Mus musculus OX=10090 GN=Simc1 PE=4 SV=1 CANONICAL=E9Q6E9-1"
            },
            "locus": {
                "chromosome": "13",
                "start_pos": 54684953,
                "end_pos": 54651689,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000138869.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000138869.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000124474.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000124474.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "E9PYI6-1",
            "url": "",
            "sequence": {
                "sequence": "MEDFIVISDDSGSESSAGTRSGRARRLRRALSRTPGALPRRTVSKGQKLEPIPHRRLRMVTNTIEENFPLGTVQFLMDFVSPQHYPPREIVAHIVQKILLSGSETVDVLKEAYMLLMKIQQLHPANAKTVEWDWKLLTYVMEEEGQTLPGRVLFLRYVVQTLEDDFQQILRRQRQHLQQSIANTVLSCDKQPHNVRDVIKWLVKAVTENELTPPQDETQTSPRTGVLKTSSDHLSPRPNQNKNTNQLIVCQLQRMLSIAVEVDRTPTCSSNKIAEMMFGFVLDIPERSQREMFFTTMESHLLRCKVLEIIFLHSCETPTRLPLSLAQTLYFLNNSTSLLKCQSDKTQWQTWDELVEHLQFLLSSYQHVLREHLRSSVIDRKDLIIKRIKPKPQQGDDITVLDVEKQIEAFRSRLVHILGEPLVPQLQDKVHLLKLLLFYAADLNPDTEPASEH",
                "length": 453,
                "header": "tr|E9PYI6-1|E9PYI6_MOUSE Computationally mapped isoform of SUMO-interacting motifs containing 1  OS=Mus musculus OX=10090 GN=Simc1 PE=1 SV=1 CANONICAL=E9Q6E9-1"
            },
            "locus": {
                "chromosome": "13",
                "start_pos": 54698443,
                "end_pos": 54651689,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000118072.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000118072.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000112376.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000112376.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "E9Q6E9-1",
            "url": "",
            "sequence": {
                "sequence": "MEDFIVISDDSGSESSAGTRSGRARRLRRALSRTPGALPRRTVDFIDLTRENRARTKDRNGLCVIDLTRNEEENRPIATLDLTLEPVASSQKEPTSLQTCTSLSGKEVMEAHEDRGSQPAAQRIINNDPVDLDLLEENLFEGSRPPTSISQDSVYPPEPNCSSITYKGDLSFLTSLQLSSDVSSFSSTSNQRASLPCPQQDVPCQSQGLLCPLQALSCPQTASPCPPRASSCPPQALSCPPQALSCPSQTLQCQLQALPQPPQEVPCSTQNVPCPQQNMPSTPQGLSWHPRHTLYPYQDTLGLPQDVPGRPQNMSYPQDVTQLQDMPWSLHDMPLSLQDVLQSLQDVPPLLGDVPPSPEVMQLPGYVTQTSRDVIQSPAGVTQSLGSMMQSPGSVTQSLRSVMQSSGSVTQSLRSVMQSSGSVTQSLRSVMQSSGSVMQSPGGVTQSLRSVTQSPGGVMQSPGGVMQSPRDVMQSPRDVMQSPRDVMQSPRGVTQSLGSMMQSPGGVMQSLRSVMQSSGGVTQSLRSVMQSPGGVMQSPGGVTQSPRGMIKSPGMMLSPGDVIQSLNSVPQSSRDRMQSAGHVPSASGDAIQSPGGMSPTSRDRMQSPGGVSLATEDSIQLPGGVPLSSDVIQSQGGVPLSSKDRMQSPGGVPPSSGDMIQSQGGVPQSLGDAIQSAGGVPQSSGDAIQSPGGVSLATGDSIQLPGGVPLSSGDVIQSQGGVPRSSRDRMQSPGGVPPSSGGVIQSPGGVSPASGDAIQSPGSVLPASGDAIQSAGGVLLASGDAIQSPRSVPQSPSGTLRSPGNMSESLGDTPNLSGDVSNSPQALLDLARDRPKSSPNDVQNRDTPMDISASSSSSCSANPQSRQSEFKLDKVPWLTITDSSARREKSLPQLANPGSAQIQGQIPQVGVYNRPCLHRLKYFLRPPVHHLFFQTLIPDKDTRESKGQKLEPIPHRRLRMVTNTIEENFPLGTVQFLMDFVSPQHYPPREIVAHIVQKILLSGSETVDVLKEAYMLLMKIQQLHPANAKTVEWDWKLLTYVMEEEGQTLPGRVLFLRYVVQTLEDDFQQILRRQRQHLQQSIANTVLSCDKQPHNVRDVIKWLVKAVTENELTPPQDETQTSPRTGVLKTSSDHLSPRPNQNKNTNQLIVCQLQRMLSIAVEVDRTPTCSSNKIAEMMFGFVLDIPERSQREMFFTTMESHLLRCKVLEIIFLHSCETPTRLPLSLAQTLYFLNNSTSLLKCQSDKTQWQTWDELVEHLQFLLSSYQHVLREHLRSSVIDRKDLIIKRIKPKPQQGDDITVLDVEKQIEAFRSRLVHILGEPLVPQLQDKVHLLKLLLFYAADLNPDTEPASEH",
                "length": 1354,
                "header": "sp|E9Q6E9-1|SIMC1_MOUSE Isoform 1 of SUMO-interacting motif-containing protein 1  OS=Mus musculus OX=10090 GN=Simc1 PE=1 SV=1 CANONICAL=E9Q6E9-1"
            },
            "locus": {
                "chromosome": "13",
                "start_pos": 54698443,
                "end_pos": 54651689,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000121401",
                        "url": "https://www.ensembl.org/id/ENSMUST00000121401"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000113676",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000113676"
                    }
                ]
            }
        },
        {
            "isoform_ac": "E9Q6E9-2",
            "url": "",
            "sequence": {
                "sequence": "MQYSHQEVCYRHQEMQYSQQEVCYWHQEMQCSANPQSRQSEFKLDKVPWLTITDSSARREKSLPQLANPGSAQIQGQIPQVGVYNRPCLHRLKYFLRPPVHHLFFQTLIPDKDTRESKGQKLEPIPHRRLRMVTNTIEENFPLGTVQFLMDFVSPQHYPPREIVAHIVQKILLSGSETVDVLKEAYMLLMKIQQYEPLQLHPANAKTVEWDWKLLTYVMEEEGQTLPGRVLFLRYVVQTLEDDFQQILRRQRQHLQQSIANTVLSCDKQPHNVRDVIKWLVKAVTENELTPPQDETQTSPRTGVLKTSSDHLSPRPNQNKNTNQLIVCQLQRMLSIAVEVDRTPTCSSNKIAEMMFGFVLDIPERSQREMFFTTMESHLLRCKVLEIIFLHSCETPTRLPLSLAQTLYFLNNSTSLLKCQSDKTQWQTWDELVEHLQFLLSSYQHVLREHLRSSVIDRKDLIIKRIKPKPQQGDDITVLDVEKQIEAFRSRLVHILGEPLVPQLQDKVHLLKLLLFYAADLNPDTEPASEH",
                "length": 531,
                "header": "sp|E9Q6E9-2|SIMC1_MOUSE Isoform 2 of SUMO-interacting motif-containing protein 1  OS=Mus musculus OX=10090 GN=Simc1 PE=1 SV=1 CANONICAL=E9Q6E9-1"
            },
            "locus": {}
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "PLEIAD/SIMC1/C5orf25, a novel autolysis regulator for a skeletal-muscle-specific calpain, CAPN3, scaffolds a CAPN3 substrate, CTBP1.",
            "journal": "J. Mol. Biol.",
            "date": "2013",
            "authors": "Ono Y, Iemura S, Novak SM, Doi N, Kitamura F, Natsume T, Gregorio CC, Sorimachi H",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "E9Q6E9",
                    "url": "https://www.uniprot.org/uniprot/E9Q6E9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "23707407",
                    "url": "https://glygen.org/publication/PubMed/23707407"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:319719",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:319719",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "F1LWT0-1",
            "protein_name": "SUMO-interacting motif-containing protein 1",
            "gene_name": "Simc1",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MEDFIVISDDSGSESSAGTRSGRARRLRRALSRTPGALPRRTVDFIDLTRETRTRAKDRNGLCVIDLTRSEEENRPIATLDLTLEPVASSQKEPPSLQTCTNLSGKEMIEAQGDRGTQPAAQRVINNDPVDLDLLEENMFEGSRPPTSISQDSVYPPEPNCSSITYKGDLSFLTSLQLSSDVSPFSSTSNNSSSSSNQRTSLPCPQQDVPCQSQGLLCSLQALSYPLRGSPCPPRASSCPPQALSCPPQALSSLSCPSQTVQCQLQALPQPPQEVPCSTQNVPCPQQNIPSTPQDLPWHPRHPLYPSQDTLGLPQDVPGRPQNVSYPQDMTQLQDMPWSLQDMPLSLQDVLQSLQDVPPLLGDVPQSPEVMQLPGYMTQSSRNVIQSSAGVIRSSGGVMQPSGCMMQPSGGVTQSLRSAIQSSGGVMQSSGVTQSLRSVMQSSGGVMQSSGVTQSSGGVTWSLRSVMQSSGCMMQSPGGVMLSAGDMMQSSGGATRSLRSMMQSSGCMMQSPGGVTQSSGSVMQSLRNVIQSSGGVTQSSGGVIQSSSGVPQSLRDRMQSPGSVSQSSGDVIQSPRGASPASGDVIKSQGGMPRSLRDRMQSPGGVPQSSEDVIQSAGGVSPASGDAIQSPGGVSPASGDAMQSSGGVTPSLGDVPQSSGGVSPASGDAMQSPGGVTPSLGDAMQSPGGVSPASGDAMQSPGGVSPSLGDVPQSPGNMLESLGNTPNLSGDVSHVPQELLDLAKGRPKLSLNAVQNRHSPMTISAPSSPSCSANPLSQQSEFSSEKRPWLTVSNSSAREERSLPQSATPGSAQIQGQIAQAGVYNRPCLHRLKYFLRPPVHHLFFQTLIPDKDTRESKGQKLEPIPHRRLRMVTNTIEENFPLGTVQFLMDFVSPQHYPPREIVAHIIQKILLSGSETVDVLKEAYMLLMKIQQLHPANAKTVEWDWKLLTYVMEEEGQTLPGRVLFLRYVVQTLEDDFQQILRRQRQHLQQSIANTVLSCDKQPHNVRDVIKWLVKAVTENALTPPQDETQTSPGPGVLKTSSDHLSPQPNLARNTNQLIVCQLQRMLSIAVEVDRTPTCSSNKIAEMMFGFVLDIPERSQREMFFTTMESHLLRCKVLEIIFLHSCETPTRLPLSLAQALYFLNNSTSLLKCQSDKSQWQTWDELVEHLQFLLSSYQHVLREHLRSSVIDRKDLIIKRIKPKPQQGDDITVVDVEKQIEAFRSRLVHILGEPLVPQLQDKVHLLKLLLFYAADLNPDTEPASER",
                "length": 1266
            },
            "evidence": [
                {
                    "id": "45240067",
                    "url": "http://www.informatics.jax.org/homology/45240067",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q8NDZ2-1",
            "protein_name": "SUMO-interacting motif-containing protein 1",
            "gene_name": "SIMC1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MAPASASGEDLRKLPTMAEVNGEQDFIDLTRETRPRTKDRSGLYVIDLTRAEGENRPIATLDLTLEPVTPSQKEPTSLQTCASLSGKAVMEGHVDRSSQPTARRIINSDPVDLDLVEENTFVGPPPATSISGGSVYPTEPNCSSATFTGNLSFLASLQLSSDVSSLSPTSNNSRSSSSSSNQKAPLPCPQQDVSRPPQALPCPLRPLPCPPRASPCPPRASSCPPRALSCPSQTMQCQLPALTHPPQEVPCPRQNIPGPPQDSLGLPQDVPGLPQSILHPQDVAYLQDMPRSPGDVPQSPSDVSPSPDAPQSPGGMPHLPGDVLHSPGDMPHSSGDVTHSPRDIPHLPGDRPDFTQNDVQNRDMPMDISALSSPSCSPSPQSETPLEKVPWLSVMETPARKEISLSEPAKPGSAHVQSRTPQGGLYNRPCLHRLKYFLRPPVHHLFFQTLIPDKDTRENKGQKLEPIPHRRLRMVTNTIEENFPLGTVQFLMDFVSPQHYPPREIVAHIIQKILLSGSETVDVLKEAYMLLMKIQQLHPANAKTVEWDWKLLTYVMEEEGQTLPGRVLFLRYVVQTLEDDFQQTLRRQRQHLQQSIANMVLSCDKQPHNVRDVIKWLVKAVTEDGLTQPPNGNQTSSGTGILKASSSHPSSQPNLTKNTNQLIVCQLQRMLSIAVEVDRTPTCSSNKIAEMMFGFVLDIPERSQREMFFTTMESHLLRCKVLEIIFLHSCETPTRLPLSLAQALYFLNNSTSLLKCQSDKSQWQTWDELVEHLQFLLSSYQHVLREHLRSSVIDRKDLIIKRIKPKPQQGDDITVVDVEKQIEAFRSRLIQMLGEPLVPQLQDKVHLLKLLLFYAADLNPDAEPFQKGWSGS",
                "length": 872
            },
            "evidence": [
                {
                    "id": "45240067",
                    "url": "http://www.informatics.jax.org/homology/45240067",
                    "database": "MGI"
                },
                {
                    "id": "E9Q6E9",
                    "url": "https://omabrowser.org/oma/group/E9Q6E9/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 1,
                "go_terms": [
                    {
                        "name": "negative regulation of peptidase activity",
                        "id": "GO:0010466",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010466",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9Q6E9",
                                "url": "https://www.uniprot.org/uniprot/E9Q6E9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9Q6E9",
                                "url": "https://www.uniprot.org/uniprot/E9Q6E9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "sarcomere",
                        "id": "GO:0030017",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030017",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9Q6E9",
                                "url": "https://www.uniprot.org/uniprot/E9Q6E9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "peptidase inhibitor activity",
                        "id": "GO:0030414",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030414",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9Q6E9",
                                "url": "https://www.uniprot.org/uniprot/E9Q6E9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "SUMO polymer binding",
                        "id": "GO:0032184",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032184",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9Q6E9",
                                "url": "https://www.uniprot.org/uniprot/E9Q6E9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 1234,
            "end_pos": 1236,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 1235,
            "end_pos": 1237,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 160,
            "end_pos": 162,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 313,
            "end_pos": 315,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 805,
            "end_pos": 807,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 815,
            "end_pos": 817,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
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                {
                    "field": "n_linked_glycans",
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                },
                {
                    "field": "n_linked_glycan_sites",
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                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
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                {
                    "field": "n_linked_glycans",
                    "count": 0
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                {
                    "field": "n_linked_glycan_sites",
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                {
                    "field": "o_linked_glycans",
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                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
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                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
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                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
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                {
                    "field": "n_linked_glycans",
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                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
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                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
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                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
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            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
            "table_stats": [
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                    "field": "total",
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                {
                    "field": "total_sites",
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            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
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                    "field": "total",
                    "count": 1
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            ],
            "sort_fields": [
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                "date",
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        }
    ]
}