{ "uniprot_canonical_ac": "E9PX82-1", "uniprot_ac": "E9PX82", "uniprot_id": "E9PX82_MOUSE", "mass": { "chemical_mass": 36139.0, "monoisotopic_mass": 36139.0 }, "refseq": { "ac": "NP_666772", "name": "olfactory receptor family 7 subfamily E member 177", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_666772" }, "gene_names": [ { "name": "Or7e177", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/E9PX82", "id": "E9PX82" }, { "name": "MOR145-2; Olfr873", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_666772", "id": "NP_666772" }, { "name": "Olfr873", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/E9PX82", "id": "E9PX82" }, { "name": "Or7e177", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_666772", "id": "NP_666772" } ], "protein_names": [ { "name": "Olfactory receptor", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "E9PX82" }, { "name": "olfactory receptor MOR145-2; olfactory receptor 873; GA_x6K02T2PVTD-14040245-14041204", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_666772", "id": "NP_666772" }, { "name": "olfactory receptor family 7 subfamily E member 177", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_666772", "id": "NP_666772" } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_666772", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_666772" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9PX82", "url": "https://www.uniprot.org/uniprot/E9PX82" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Or7e177", "url": "https://www.uniprot.org/uniprot/E9PX82", "locus": { "chromosome": "9", "start_pos": 20214895, "end_pos": 20209828, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000049028", "url": "https://www.ensembl.org/id/ENSMUSG00000049028" } ] } } ], "crossref": [ { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "258554", "url": "https://www.ncbi.nlm.nih.gov/gene/258554", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:258554", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:258554", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "3030707", "url": "http://www.informatics.jax.org/marker/MGI:3030707", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "QVHNMIV", "url": "https://omabrowser.org/oma/group/QVHNMIV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "5401587at2759", "url": "http://www.orthodb.org/?query=5401587at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001:SF178", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001:SF178", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "http://pfam.xfam.org/family/PF13853", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "A0A2I3BPK1", "url": "https://www.uniprot.org/uniprot/A0A2I3BPK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A2I3BPK1-1", "url": "https://www.uniprot.org/uniprot/A0A2I3BPK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9PX82", "url": "https://www.uniprot.org/uniprot/E9PX82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9PX82-1", "url": "https://www.uniprot.org/uniprot/E9PX82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8VFJ0", "url": "https://www.uniprot.org/uniprot/Q8VFJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8VFJ0-1", "url": "https://www.uniprot.org/uniprot/Q8VFJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLQRHSLGHCSNNIELQNLTLVSEFHLMRISDDPELQPILFGLFLSMYLVTVLGNLIIILAVNSDSNLHTPMYFFLCNLSLADICFISTTVPKMIVNIQTHSKEIIYVGCLTQMSFLILFGCMDGLLLTVMAYDRFVAVCHPLHYSLIMNPRLCGSLVCLSLLISLVDSQAHNLIALQIIYFKDVKISNFFCDPAQLLNLACFNTFINNIVMYFVGAISGLLPISGIFFSYYKIVFSILKIPSKGGRYKAFSTCGSHLSVVCLFYGTAIGVYLGSAVSHSPRSTAVASLIYTVVTPMLNPFIYSLRNKDIKRAVKRLHRRML", "length": 323, "header": "tr|E9PX82-1|E9PX82_MOUSE Isoform 1 of Olfactory receptor OS=Mus musculus OX=10090 GN=Or7e177 PE=3 SV=2 CANONICAL=E9PX82-1" }, "isoforms": [ { "isoform_ac": "A0A2I3BPK1-1", "url": "", "sequence": { "sequence": "MWLIQHSINCSNNIELQNLTLVSEFHLMRISDDPELQPILFGLFLSMYLVTVLGNLIIILAVNSDSNLHTPMYFFLCNLSLADICFISTTVPKMIVNIQTHSKEIIYVGCLTQMSFLILFGCMDGLLLTVMAYDRFVAVCHPLHYSLIMNPRLCGSLVCLSLLISLVDSQAHNLIALQIIYFKDVKISNFFCDPAQLLNLACFNTFINNIVMYFVGAISGLLPISGIFFSYYKIVFSILKIPSKGGRYKAFSTCGSHLSVVCLFYGTAIGVYLGSAVSHSPRSTAVASLIYTVVTPMLNPFIYSLRNKDIKRAVKRLHRRML", "length": 322, "header": "tr|A0A2I3BPK1-1|A0A2I3BPK1_MOUSE Computationally mapped isoform of Olfactory receptor OS=Mus musculus OX=10090 GN=Or7e177 PE=3 SV=1 CANONICAL=E9PX82-1" }, "locus": { "chromosome": "9", "start_pos": 20212463, "end_pos": 20210358, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000215540.2", "url": "https://www.ensembl.org/id/ENSMUST00000215540.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000153816.2", "url": "https://www.ensembl.org/id/ENSMUSP00000153816.2" } ] } }, { "isoform_ac": "E9PX82-1", "url": "", "sequence": { "sequence": "MSLQRHSLGHCSNNIELQNLTLVSEFHLMRISDDPELQPILFGLFLSMYLVTVLGNLIIILAVNSDSNLHTPMYFFLCNLSLADICFISTTVPKMIVNIQTHSKEIIYVGCLTQMSFLILFGCMDGLLLTVMAYDRFVAVCHPLHYSLIMNPRLCGSLVCLSLLISLVDSQAHNLIALQIIYFKDVKISNFFCDPAQLLNLACFNTFINNIVMYFVGAISGLLPISGIFFSYYKIVFSILKIPSKGGRYKAFSTCGSHLSVVCLFYGTAIGVYLGSAVSHSPRSTAVASLIYTVVTPMLNPFIYSLRNKDIKRAVKRLHRRML", "length": 323, "header": "tr|E9PX82-1|E9PX82_MOUSE Isoform 1 of Olfactory receptor OS=Mus musculus OX=10090 GN=Or7e177 PE=3 SV=2 CANONICAL=E9PX82-1" }, "locus": { "chromosome": "9", "start_pos": 20212463, "end_pos": 20209910, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000075717.7", "url": "https://www.ensembl.org/id/ENSMUST00000075717.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000075135.6", "url": "https://www.ensembl.org/id/ENSMUSP00000075135.6" } ] } }, { "isoform_ac": "Q8VFJ0-1", "url": "", "sequence": { "sequence": "MFIFKSCSNNIELQNLTLVSEFHLMRISDDPELQPILFGLFLSMYLVTVLGNLIIILAVNSDSNLHTPMYFFLCNLSLADICFISTTVPKMIVNIQTHSKEIIYVGCLTQMSFLILFGCMDGLLLTVMAYDRFVAVCHPLHYSLIMNPRLCGSLVCLSLLISLVDSQAHNLIALQIIYFKDVKISNFFCDPAQLLNLACFNTFINNIVMYFVGAISGLLPISGIFFSYYKIVFSILKIPSKGGRYKAFSTCGSHLSVVCLFYGTAIGVYLGSAVSHSPRSTAVASLIYTVVTPMLNPFIYSLRNKDIKRAVKRLHRRML", "length": 319, "header": "tr|Q8VFJ0-1|Q8VFJ0_MOUSE Computationally mapped isoform of Olfactory receptor OS=Mus musculus OX=10090 GN=Or7e177 PE=2 SV=1 CANONICAL=E9PX82-1" }, "locus": { "chromosome": "9", "start_pos": 20212463, "end_pos": 20211507, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000053919.5", "url": "https://www.ensembl.org/id/ENSMUST00000053919.5" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000054778.5", "url": "https://www.ensembl.org/id/ENSMUSP00000054778.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "mmu:258554", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:258554", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6IFN5-1", "protein_name": "Olfactory receptor 7E24", "gene_name": "OR7E24", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYFPILFFFFLKRCPSYTEPQNLTGVSEFLLLGLSEDPELQPVLAGLFLSMYLVTVLGNLLIILAVSSDSHLHTPMYFFLSNLSLADIGFTSTTVPKMIVDMQTHSRVISYEGCLTQMSFFVLFACMDDMLLSVMAYDRFVAICHPLHYRIIMNPRLCGFLILLSFFISLLDSQLHNLIMLQLTCFKDVDISNFFCDPSQLLHLRCSDTFINEMVIYFMGAIFGCLPISGILFSYYKIVSPILRVPTSDGKYKAFSTCGSHLAVVCLFYGTGLVGYLSSAVLPSPRKSMVASVMYTVVTPMLNPFIYSLRNKDIQSALCRLHGRIIKSHHLHPFCYMG", "length": 339 }, "evidence": [ { "id": "45243045", "url": "http://www.informatics.jax.org/homology/45243045", "database": "MGI" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": 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