{ "uniprot_canonical_ac": "E9PVB5-1", "uniprot_ac": "E9PVB5", "uniprot_id": "TTC17_MOUSE", "mass": { "chemical_mass": 135521.0, "monoisotopic_mass": 135521.0 }, "refseq": { "ac": "NP_898929", "name": "tetratricopeptide repeat protein 17 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_898929" }, "gene_names": [ { "name": "Ttc17", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/E9PVB5", "id": "E9PVB5" }, { "name": "9130020K17Rik; D2Bwg1005e", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006500375", "id": "XP_006500375" }, { "name": "Ttc17", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006500375", "id": "XP_006500375" } ], "protein_names": [ { "name": "Tetratricopeptide repeat protein 17", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "E9PVB5" }, { "name": "TPR repeat protein 17; tetratricopeptide repeat protein 17", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_898929", "id": "NP_898929" }, { "name": "TPR repeat protein 17", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "E9PVB5" }, { "name": "tetratricopeptide repeat protein 17 isoform 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_898929", "id": "NP_898929" }, { "name": "tetratricopeptide repeat protein 17 isoform X2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006500375", "id": "XP_006500375" } ], "function": [ { "annotation": "Plays a role in primary ciliogenesis by modulating actin polymerization.", "evidence": [ { "database": "UniProtKB", "id": "E9PVB5", "url": "https://www.uniprot.org/uniprot/E9PVB5#function" } ] } ], "disease": [], "snv": [ { "evidence": [ { "id": "rs3388573687", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388573687" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "start_pos": 232, "end_pos": 232, "sequence_org": "A", "sequence_mut": "S", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (NLA->NLS).", "chr_id": "2", "chr_pos": "94206454", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A232", "keywords": [ "ebi", "germline" ] } ], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9PVB5", "url": "https://www.uniprot.org/uniprot/E9PVB5" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Ttc17", "url": "https://www.uniprot.org/uniprot/E9PVB5", "locus": { "chromosome": "2", "start_pos": 94131112, "end_pos": 94237034, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000027194", "url": "https://www.ensembl.org/id/ENSMUSG00000027194" } ] } } ], "crossref": [ { "id": "ENSMUSG00000027194", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000027194", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "74569", "url": "https://www.ncbi.nlm.nih.gov/gene/74569", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "2762", "url": "https://glyconnect.expasy.org/browser/proteins/2762", "database": "GlyConnect", "categories": [ "Glycan", "Glycoproteomics" ] }, { "id": "GPDB0001645", "url": "https://acgg.asia/db/gpdb/symbol/GPDB0001645", "database": "GlycoProtDB", "categories": [ "Glycoproteomics" ] }, { "id": "GPDB0002358", "url": "https://acgg.asia/db/gpdb/symbol/GPDB0002358", "database": "GlycoProtDB", "categories": [ "Glycoproteomics" ] }, { "id": "GPDB0002359", "url": "https://acgg.asia/db/gpdb/symbol/GPDB0002359", "database": "GlycoProtDB", "categories": [ "Glycoproteomics" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:74569", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:74569", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "1921819", "url": "http://www.informatics.jax.org/marker/MGI:1921819", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "NLYQMAL", "url": "https://omabrowser.org/oma/group/NLYQMAL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "5391094at2759", "url": "http://www.orthodb.org/?query=5391094at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16091", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16091", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16091:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16091:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13181", "url": "http://pfam.xfam.org/family/PF13181", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_E9PVB5", "url": "http://purl.obolibrary.org/obo/PR_E9PVB5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_898929", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_898929", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2AFY7", "url": "https://www.uniprot.org/uniprot/A2AFY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2AFY7-1", "url": "https://www.uniprot.org/uniprot/A2AFY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2AGG1", "url": "https://www.uniprot.org/uniprot/A2AGG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2AGG1-1", "url": "https://www.uniprot.org/uniprot/A2AGG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9PVB5", "url": "https://www.uniprot.org/uniprot/E9PVB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9PVB5-1", "url": "https://www.uniprot.org/uniprot/E9PVB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9PVB5-2", "url": "https://www.uniprot.org/uniprot/E9PVB5-2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAIGVRGRFELLPRSGPGWLLSLSALLSVVARGALATTHWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQETTVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDIRPEDFIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNASSWVLYNLASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALDDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQFGDDSSTSSMMSVNFDVPTNQSDVSESVRSSPVAHSVLWVWGRDSDAYRDKQHILWPKRADCTDSYPRVPLGGELPTYFLPPENKGLRIHELTSDDYSSEEEAQPPDCSITDYRKSHTLSYLVKELEVRMDLKAKIPDDHARKILLSRIKNYTVPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKLSTKCPECESSLKLIRCMQFYPFLYNATSSVCGGHCHEKPLDNSHDKQKYFAKPQSLDAAAEEPSGHGADEDPVLSVENAGRDSDALRLESTVVEESNGSDEVEKSDETKMSEEILALVDEFQQAWPLEGFGGTLEMKGRRLDLQGIRVLKKGPQDGVAKSSCYGDCRSEDDEATEWITFQVKRVKKPKGDHKKPPGKKVEASQAENGQRYQANLEITGPKVASPGPQEKKRDYQSLGWPSPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRSP", "length": 1198, "header": "sp|E9PVB5-1|TTC17_MOUSE Isoform 1 of Tetratricopeptide repeat protein 17 OS=Mus musculus OX=10090 GN=Ttc17 PE=1 SV=1 CANONICAL=E9PVB5-1" }, "isoforms": [ { "isoform_ac": "A2AFY7-1", "url": "", "sequence": { "sequence": "MAAAIGVRGRFELLPRSGPGWLLSLSALLSVVARGALATTHWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQETTVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDIRPEDFIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNASSWVLYNLASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALDDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQFGDDSSTSSMMSVNFDVPTNQSDVSESVRSSPVAHSVLWVWGRDSDAYRDKQHILWPKRADCTDSYPRVPLGGELPTYFLPPENKGLRIHELTSDDYSSEEEAQPPDCSITDYRKSHTLSYLVKELEVRMDLKAKIPDDHARKILLSRIKNYTVPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKLSTKCPECESSLKLIRCMQFYPFLYNATSSVCGGHCHEKPLDNSHDKQKYFAKPQSLDAAAEEPSGHGADEDPVLSVENAGRDSDALRLESTVVEESNGSDEVEKSDETKMSEEILALVDEFQQAWPLEGFGGTLEMKGRRLDLQGIRVLKKGPQDGVAKSSCYGDCRSEDDEATEWITFQVKRVKKPKGDHKKPPGKKVEASQAENGQRYQANLEITGPKVASPGPQGLLDWKTREVP", "length": 956, "header": "tr|A2AFY7-1|TTC17_MOUSE Computationally mapped isoform of Tetratricopeptide repeat protein 17 OS=Mus musculus OX=10090 GN=Ttc17 PE=1 SV=1 CANONICAL=E9PVB5-1" }, "locus": { "chromosome": "2", "start_pos": 94237010, "end_pos": 94158799, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000094801.5", "url": "https://www.ensembl.org/id/ENSMUST00000094801.5" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000092395.5", "url": "https://www.ensembl.org/id/ENSMUSP00000092395.5" } ] } }, { "isoform_ac": "A2AGG1-1", "url": "", "sequence": { "sequence": "MDLKAKIPDDHARKILLSRIKNYTVPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKLSTKCPECESSLKLIRCMQFYPFLYNATSSVCGGHCHEKPLDNSHDKQKYFAKPQSLDAAAEEPSGHGADEDPVLSVENAGRDSDALRLESTVVEESNGSDEVEKSDETKMSEEILALVDEFQQAWPLEGFGGTLEMKGRRLDLQGIRVLKKGPQDGVAKSSCYGDCRSEDDEATEWITFQVKRVKKPKGDHKKPPGKKVEASQAENGQRYQANLEITGPKVASPGPQEKKRDYQSLGWPSPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRSP", "length": 625, "header": "tr|A2AGG1-1|A2AGG1_MOUSE Computationally mapped isoform of Tetratricopeptide repeat domain 17 OS=Mus musculus OX=10090 GN=Ttc17 PE=1 SV=1 CANONICAL=E9PVB5-1" }, "locus": { "chromosome": "2", "start_pos": 94194652, "end_pos": 94132084, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000055081.14", "url": "https://www.ensembl.org/id/ENSMUST00000055081.14" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000061360.8", "url": "https://www.ensembl.org/id/ENSMUSP00000061360.8" } ] } }, { "isoform_ac": "E9PVB5-1", "url": "", "sequence": { "sequence": "MAAAIGVRGRFELLPRSGPGWLLSLSALLSVVARGALATTHWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQETTVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDIRPEDFIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNASSWVLYNLASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALDDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQFGDDSSTSSMMSVNFDVPTNQSDVSESVRSSPVAHSVLWVWGRDSDAYRDKQHILWPKRADCTDSYPRVPLGGELPTYFLPPENKGLRIHELTSDDYSSEEEAQPPDCSITDYRKSHTLSYLVKELEVRMDLKAKIPDDHARKILLSRIKNYTVPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKLSTKCPECESSLKLIRCMQFYPFLYNATSSVCGGHCHEKPLDNSHDKQKYFAKPQSLDAAAEEPSGHGADEDPVLSVENAGRDSDALRLESTVVEESNGSDEVEKSDETKMSEEILALVDEFQQAWPLEGFGGTLEMKGRRLDLQGIRVLKKGPQDGVAKSSCYGDCRSEDDEATEWITFQVKRVKKPKGDHKKPPGKKVEASQAENGQRYQANLEITGPKVASPGPQEKKRDYQSLGWPSPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRSP", "length": 1198, "header": "sp|E9PVB5-1|TTC17_MOUSE Isoform 1 of Tetratricopeptide repeat protein 17 OS=Mus musculus OX=10090 GN=Ttc17 PE=1 SV=1 CANONICAL=E9PVB5-1" }, "locus": { "chromosome": "2", "start_pos": 94237010, "end_pos": 94132084, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000111238", "url": "https://www.ensembl.org/id/ENSMUST00000111238" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000106869", "url": "https://www.ensembl.org/id/ENSMUSP00000106869" } ] } }, { "isoform_ac": "E9PVB5-2", "url": "", "sequence": { "sequence": "MAAAIGVRGRFELLPRSGPGWLLSLSALLSVVARGALATTHWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQETTVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDIRPEDFIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNASSWVLYNLASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALDDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQFGDDSSTSSMMSVNFDVPTNQSDVSESVRSSPVAHSVLWVWGRDSDAYRDKQHILWPKRADCTDSYPRVPLGGELPTYFLPPENKGLRIHELTSDDYSSEEEAQPPDCSITDYRKSHTLSYLVKELEVRMDLKAKIPDDHARKILLSRIKNYTVPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKLSTKCPECESSLKLIRCMQFYPFLYNATSSVCGGTVVEESNGSDEVEKSDETKMSEEILALVDEFQQAWPLEGFGGTLEMKGRRLDLQGIRVLKKGPQDGVAKSSCYGDCRSEDDEATEWITFQVKRVKKPKGDHKKPPGKKVEASQAENGQRYQANLEITGPKVASPGPQEKKRDYQSLGWPSPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRSP", "length": 1141, "header": "sp|E9PVB5-2|TTC17_MOUSE Isoform 2 of Tetratricopeptide repeat protein 17 OS=Mus musculus OX=10090 GN=Ttc17 PE=1 SV=1 CANONICAL=E9PVB5-1" }, "locus": { "chromosome": "2", "start_pos": 94237010, "end_pos": 94132084, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000111237", "url": "https://www.ensembl.org/id/ENSMUST00000111237" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000106868", "url": "https://www.ensembl.org/id/ENSMUSP00000106868" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G64527OM", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 815, "start_aa": "Asn", "end_pos": 815, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn815", "evidence": [ { "id": "2762", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2762" }, { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2762", "url": "https://glyconnect.expasy.org/browser/proteins/2762" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] } ], "pathway": [ { "id": "mmu:74569", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:74569", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B5DEL3-1", "protein_name": "Tetratricopeptide repeat protein 17", "gene_name": "Ttc17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAIGVRGRFELLSCSGPGWLISLSALLSVVARGALATTHWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQETTVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDVRPEDFIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNSSSWVLYNLASFYWRIKNEPYQVVECTMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALDDSAFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQFGDDSSTSSMMSVNFDVPTNQSDVSESVRSSPVAHSVLWVWGRDSDAYRDKQHILWPKRADCTDSYPRVPLGGELPTYFLPPENKGLRIHELTSDDYSSEEEAQTPDCSITDFRKSHTLSYLVKELEVRMDLKAKIPDDHARKILLSRIKNYTIPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQALAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKLTTRCPECESSLKLIRCMQFYPFLYNITSSVCSGHCHEKTLDNSHDKQKYFAKPQSLDAAEEEPSRHGADEDPVLSVENAGRDSDALRLESTVVEESNGSDEVEKSEETKMSEEILALVDEFQQAWPLEGLGGTLEMKGRRLDLQGIRVLKKGPQDGVAKSSCYGDCRSEDDEATEWITFQVKRVKKPKGDHKKPPGKKVEASQAENGQRYQANLEITGPKVASPGPQEKKRDYQSMGWPSPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVVVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRSP", "length": 1198 }, "evidence": [ { "id": "45230250", "url": "http://www.informatics.jax.org/homology/45230250", "database": "MGI" }, { "id": "E9PVB5", "url": "https://omabrowser.org/oma/group/E9PVB5/", "database": "OMA" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96AE7-1", "protein_name": "Tetratricopeptide repeat protein 17", "gene_name": "TTC17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAVGVRGRYELPPCSGPGWLLSLSALLSVAARGAFATTHWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQEATVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDISPEDYIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNTSSWVLYNMASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALDDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQARPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQFGEDSSTSSMMSVNFDVQSNQSDINDSVKSSPVAHSILWIWGRDSDAYRDKQHILWPKRADCTESYPRVPVGGELPTYFLPPENKGLRIHELSSDDYSTEEEAQTPDCSITDFRKSHTLSYLVKELEVRMDLKAKMPDDHARKILLSRINNYTIPEEEIGSFLFHAINKPNAPIWLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPLVNLANLLIHYGLHLDATKLLLQALAINSSEPLTFLSLGNAYLALKNISGALEAFRQALKLTTKCPECENSLKLIRCMQFYPFLYNITSSVCSGTVVEESNGSDEMENSDETKMSEEILALVDEFQQAWPLEGFGGALEMKGRRLDLQGIRVLKKGPQDGVARSSCYGDCRSEDDEATEWITFQVKRVKKPKGDHKKTPGKKVETGQIENGHRYQANLEITGPKVASPGPQGKKRDYQRLGWPSPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRSP", "length": 1141 }, "evidence": [ { "id": "45230250", "url": "http://www.informatics.jax.org/homology/45230250", "database": "MGI" }, { "id": "E9PVB5", "url": "https://omabrowser.org/oma/group/E9PVB5/", "database": "OMA" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E9PVB5", "url": "https://www.uniprot.org/uniprot/E9PVB5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E9PVB5", "url": "https://www.uniprot.org/uniprot/E9PVB5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E9PVB5", "url": "https://www.uniprot.org/uniprot/E9PVB5" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "E9PVB5", "url": "https://www.uniprot.org/uniprot/E9PVB5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "actin filament polymerization", "id": "GO:0030041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030041", "evidence": [ { "database": "UniProtKB", "id": "E9PVB5", "url": "https://www.uniprot.org/uniprot/E9PVB5" } ], "pmid": "" }, { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "E9PVB5", "url": "https://www.uniprot.org/uniprot/E9PVB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1068, "end_pos": 1070, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { 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}, { "field": "total_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 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