{
    "uniprot_canonical_ac": "E9PTX3-1",
    "uniprot_ac": "E9PTX3",
    "uniprot_id": "E9PTX3_RAT",
    "mass": {
        "chemical_mass": 83463.0,
        "monoisotopic_mass": 83463.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Hook2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/E9PTX3",
            "id": "E9PTX3"
        }
    ],
    "protein_names": [
        {
            "name": "Hook microtubule-tethering protein 2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "E9PTX3"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:11726",
            "recommended_name": {
                "id": "DOID:11726",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:11726",
                "name": "Emery-Dreifuss muscular dystrophy",
                "description": "A muscular dystrophy that chiefly affects muscles used for movement (skeletal) and heart (cardiac) muscle."
            },
            "synonyms": [
                {
                    "id": "DOID:11726",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:11726",
                    "name": "EDMD",
                    "description": ""
                },
                {
                    "id": "MONDO:0010680",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010680",
                    "name": "X-linked Emery-Dreifuss muscular dystrophy",
                    "description": "X-linked form of Emery-Dreifuss muscular dystrophy."
                },
                {
                    "id": "MONDO:0010680",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010680",
                    "name": "EDMD1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010680",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010680",
                    "name": "EMD1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010680",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010680",
                    "name": "Emerinopathy",
                    "description": ""
                },
                {
                    "id": "MONDO:0010680",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010680",
                    "name": "Emery-Dreifuss muscular dystrophy 1, X-linked",
                    "description": ""
                },
                {
                    "id": "MONDO:0010680",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010680",
                    "name": "Emery-Dreifuss muscular dystrophy, X-linked",
                    "description": ""
                },
                {
                    "id": "MONDO:0010680",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010680",
                    "name": "X-linked Emery-Dreifuss muscular dystrophy",
                    "description": ""
                },
                {
                    "id": "MONDO:0010680",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010680",
                    "name": "humeroperoneal neuromuscular disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0010680",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010680",
                    "name": "muscular dystrophy, tardive, Dreifuss-Emery type, with contractures",
                    "description": ""
                },
                {
                    "id": "MONDO:0010680",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010680",
                    "name": "scapuloperoneal syndrome, X-linked",
                    "description": ""
                },
                {
                    "id": "MONDO:0010680",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010680",
                    "name": "EMERY-Dreifuss muscular dystrophy 1, X-linked",
                    "description": ""
                },
                {
                    "id": "MONDO:0010680",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010680",
                    "name": "Ehlers-Danlos syndrome, classic-like, 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010680",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010680",
                    "name": "Humeroperoneal neuromuscular disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0010680",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010680",
                    "name": "Humeroperoneal neuromuscular disease, formerly",
                    "description": ""
                },
                {
                    "id": "MONDO:0010680",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010680",
                    "name": "muscular dystrophy, tardive Emery-Dreifuss type, with contractures",
                    "description": ""
                },
                {
                    "id": "MONDO:0010680",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010680",
                    "name": "scapuloperoneal syndrome, X-linked, formerly",
                    "description": ""
                },
                {
                    "id": "MIM:310300",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/310300",
                    "name": "Emery-Dreifuss muscular dystrophy 1, X-linked",
                    "description": "Emery-Dreifuss muscular dystrophy 1, X-linked"
                }
            ],
            "evidence": [
                {
                    "id": "11726",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:11726"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "E9PTX3",
                    "url": "https://www.uniprot.org/uniprot/E9PTX3"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Hook2",
            "url": "https://www.uniprot.org/uniprot/E9PTX3",
            "locus": {
                "chromosome": "19",
                "start_pos": 23151870,
                "end_pos": 23164181,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000003682",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000003682"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000003682",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000003682",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "IPR001715",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR008636",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR008636",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036872",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR043936",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR043936",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:304669",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:304669",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "QRYKRYM",
            "url": "https://omabrowser.org/oma/group/QRYKRYM/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "50921at2759",
            "url": "http://www.orthodb.org/?query=50921at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR18947",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18947",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR18947:SF37",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18947:SF37",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF05622",
            "url": "http://pfam.xfam.org/family/PF05622",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF19047",
            "url": "http://pfam.xfam.org/family/PF19047",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "XP_006255317",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006255317",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1310171",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1310171",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "E9PTX3",
            "url": "https://www.uniprot.org/uniprot/E9PTX3",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9PTX3-1",
            "url": "https://www.uniprot.org/uniprot/E9PTX3-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MSMDKAELCGSLLTWLQTFQVSPPCASPQDLSSGLAIAHVLNQIDPSWFNDAWLQGISEDPSPSWRLKVRKLERILQSLVEYSKDVLGHPVSHQHLPDVSLIGEFSNPAELGKLLQLVLACAISCEKKQEYIQRIMMLEESVQHVVMEAIQELMTKDTPDSLSPENYGNFDTQSRRYYFLSEEVEEGGDLQQHYLDLERQLVLLSEEKQSLAQENAALRERVGRSEVESASGLTAKKLLLLQSQLEQLQEENFRLESSREDERLRCVELEREVAELQQRNQALASLSQEAQALKDEMDELRQSSERARQLEATLNSCRRRLGELQELRRQVRQLEERNAGHAERTRQLEDELRRAGSLRAQLEAQRRQMQELQGQWQEEAMKAEKWLFECQNLEEKCDLLTKEKERLLTERDSLRETNEELRCAQLQPRGLNQAGLSLDPTPSGLENLAAEILPAELRETLVRLQLENKRLCQQEAADRERQEELQRHLEEANRARHGLEAQQRLNQQQLSELRAQVEELQKALQEQGGKTDDAAPTLLKRKLEDHLQKLHEADLELQRKREYIEELEPPTDSNTARRIEELQDSLQKKDADLRAMEERYRRYVDKARTVIQTLEPKQRPPSVVSPEFHTLRSQLWERNMRIRQLEMDYEKSRSRQEQEEKLLISAWYSMGMALEHRAGEEHAPAHAQSFLAQQRLATNARRGPLGRQASLSLRPTDKH",
        "length": 719,
        "header": "tr|E9PTX3-1|E9PTX3_RAT Isoform 1 of Hook microtubule-tethering protein 2  OS=Rattus norvegicus OX=10116 GN=Hook2 PE=1 SV=3 CANONICAL=E9PTX3-1"
    },
    "isoforms": [
        {
            "isoform_ac": "E9PTX3-1",
            "url": "",
            "sequence": {
                "sequence": "MSMDKAELCGSLLTWLQTFQVSPPCASPQDLSSGLAIAHVLNQIDPSWFNDAWLQGISEDPSPSWRLKVRKLERILQSLVEYSKDVLGHPVSHQHLPDVSLIGEFSNPAELGKLLQLVLACAISCEKKQEYIQRIMMLEESVQHVVMEAIQELMTKDTPDSLSPENYGNFDTQSRRYYFLSEEVEEGGDLQQHYLDLERQLVLLSEEKQSLAQENAALRERVGRSEVESASGLTAKKLLLLQSQLEQLQEENFRLESSREDERLRCVELEREVAELQQRNQALASLSQEAQALKDEMDELRQSSERARQLEATLNSCRRRLGELQELRRQVRQLEERNAGHAERTRQLEDELRRAGSLRAQLEAQRRQMQELQGQWQEEAMKAEKWLFECQNLEEKCDLLTKEKERLLTERDSLRETNEELRCAQLQPRGLNQAGLSLDPTPSGLENLAAEILPAELRETLVRLQLENKRLCQQEAADRERQEELQRHLEEANRARHGLEAQQRLNQQQLSELRAQVEELQKALQEQGGKTDDAAPTLLKRKLEDHLQKLHEADLELQRKREYIEELEPPTDSNTARRIEELQDSLQKKDADLRAMEERYRRYVDKARTVIQTLEPKQRPPSVVSPEFHTLRSQLWERNMRIRQLEMDYEKSRSRQEQEEKLLISAWYSMGMALEHRAGEEHAPAHAQSFLAQQRLATNARRGPLGRQASLSLRPTDKH",
                "length": 719,
                "header": "tr|E9PTX3-1|E9PTX3_RAT Isoform 1 of Hook microtubule-tethering protein 2  OS=Rattus norvegicus OX=10116 GN=Hook2 PE=1 SV=3 CANONICAL=E9PTX3-1"
            },
            "locus": {
                "chromosome": "19",
                "start_pos": 23164098,
                "end_pos": 23152225,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000035987.5",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000035987.5"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000033999.5",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000033999.5"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:304669",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:304669",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 7,
                "go_terms": [
                    {
                        "name": "HOPS complex",
                        "id": "GO:0030897",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030897",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "centrosome",
                        "id": "GO:0005813",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytosol",
                        "id": "GO:0005829",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "microtubule",
                        "id": "GO:0005874",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "FHF complex",
                        "id": "GO:0070695",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070695",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "trans-Golgi network",
                        "id": "GO:0005802",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 3,
                "go_terms": [
                    {
                        "name": "microtubule binding",
                        "id": "GO:0008017",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "identical protein binding",
                        "id": "GO:0042802",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "dynein light intermediate chain binding",
                        "id": "GO:0051959",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 7,
                "go_terms": [
                    {
                        "name": "endosome organization",
                        "id": "GO:0007032",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "lysosome organization",
                        "id": "GO:0007040",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007040",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endosome to lysosome transport",
                        "id": "GO:0008333",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "early endosome to late endosome transport",
                        "id": "GO:0045022",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045022",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoskeleton-dependent intracellular transport",
                        "id": "GO:0030705",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030705",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein localization to perinuclear region of cytoplasm",
                        "id": "GO:1905719",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905719",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasmic microtubule organization",
                        "id": "GO:0031122",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "E9PTX3",
                                "url": "https://www.uniprot.org/uniprot/E9PTX3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
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