{ "uniprot_canonical_ac": "E5FYH1-1", "uniprot_ac": "E5FYH1", "uniprot_id": "TOPZ1_MOUSE", "mass": { "chemical_mass": 185487.0, "monoisotopic_mass": 185487.0 }, "refseq": { "ac": "NP_001186665", "name": "protein TOPAZ1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186665" }, "gene_names": [ { "name": "Topaz1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/E5FYH1", "id": "E5FYH1" }, { "name": "671232; Gm9524", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186665", "id": "NP_001186665" }, { "name": "Gm9524", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/E5FYH1", "id": "E5FYH1" }, { "name": "Topaz1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186665", "id": "NP_001186665" } ], "protein_names": [ { "name": "Protein TOPAZ1", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "E5FYH1" }, { "name": "Testis- and ovary-specific PAZ domain-containing protein 1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "E5FYH1" }, { "name": "protein TOPAZ1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186665", "id": "NP_001186665" }, { "name": "topaz 1; testis and ovary-specific PAZ domain gene 1; testis- and ovary-specific PAZ domain-containing protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186665", "id": "NP_001186665" } ], "function": [ { "annotation": "Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.", "evidence": [ { "database": "UniProtKB", "id": "E5FYH1", "url": "https://www.uniprot.org/uniprot/E5FYH1#function" }, { "database": "PubMed", "id": "26358182", "url": "https://glygen.org/publication/PubMed/26358182" } ] }, { "annotation": "TOPAZ1, a germ cell specific factor, is essential for male meiotic progression.", "evidence": [ { "database": "RefSeq", "id": "NP_001186665", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186665" }, { "database": "PubMed", "id": "26358182", "url": "https://glygen.org/publication/PubMed/26358182" } ] } ], "disease": [], "snv": [ { "evidence": [ { "id": "rs3400856848", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3400856848" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "start_pos": 117, "end_pos": 117, "sequence_org": "A", "sequence_mut": "S", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (NMA->NMS).", "chr_id": "9", "chr_pos": "122577440", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A117", "keywords": [ "ebi", "germline" ] } ], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E5FYH1", "url": "https://www.uniprot.org/uniprot/E5FYH1" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Topaz1", "url": "https://www.uniprot.org/uniprot/E5FYH1", "locus": { "chromosome": "9", "start_pos": 122631200, "end_pos": 122576411, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000094985", "url": "https://www.ensembl.org/id/ENSMUSG00000094985" } ] } } ], "crossref": [ { "id": "ENSMUSG00000094985", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000094985", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "671232", "url": "https://www.ncbi.nlm.nih.gov/gene/671232", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:671232", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:671232", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "3779933", "url": "http://www.informatics.jax.org/marker/MGI:3779933", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "E5FYH1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=E5FYH1", "database": "O-GlcNAc Database", "categories": [ "Glycoproteomics" ] }, { "id": "GAIWVMR", "url": "https://omabrowser.org/oma/group/GAIWVMR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "5323221at2759", "url": "http://www.orthodb.org/?query=5323221at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35671", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35671", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35671:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35671:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14669", "url": "http://pfam.xfam.org/family/PF14669", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_E5FYH1", "url": "http://purl.obolibrary.org/obo/PR_E5FYH1", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001186665", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186665", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E5FYH1", "url": "https://www.uniprot.org/uniprot/E5FYH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E5FYH1-1", "url": "https://www.uniprot.org/uniprot/E5FYH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPPATPPDPTKEPGCKGTTRGLRKRGLPLTPEPGEGGGCSLEARGCEEESRQKQRMVTQASGREETEGDKLAKENGKITEAPSDDPQPGTDLVRKTSITSSESLQTVECSEFQNMAFLQSLDKEELGEGIKRRMRIKKCKSLENPPLEITKNEATQNIKVEFQDELFKNTPKHSCNSLSPGVEKNCSFELHDYSFLHSEGCNNENNFEDKPHDVCLHTEENSLKLKKENLRNLAEKDDTRTTTKLLKTEKSVIASKLLLEESHLYQNKNNGLTSCLQSEKNKYSVEENNTGRKHRKKMKSGKEEKNINLTLSNVCNNSVLVLQENQMGMEGKEAETLEPKKSFLKALRKINHNTLPPVDHLCLPKTVGKTSSRHHINAMLQKTLESSLKEDIKNTSESLGCKRIEPEKYNKSMISSTVKSPSDGHHMEKRSPRGDLRSETEESKVSCCRTIPMTGKRVWPFYSCARISAQCWKKTSLSDLNYSLLGPLENVRQHDSIIHQMNQTHLPDSKLLQPSLTERTTESSRKEMYDSDLSCLSSVSSVESTVMDIKEAMSHDKKTKLEEPSRNGAEVVSNATEDTQLSNITQSLTGNKKRKGNLSKLNLTVASQESQETNNCANKTVHRKVCITKQTLVAPDLVKILNTGRLTNFKIPLLKNKTGKRGAVSARSSEREAYSPLELLDSLSGVEAKQNRNKENICTTSGPQSLNLHSCIAPGQASSHSFYNKNSCTSSSFTKKGYDNKACNHISEPGNIISNKESISMKIENNTFSCDLGYIDQSSFCSKKQEAFVPISSEISGRKMTKSISELKLGFPDILKAYEDDVLLIDVIQDDPELFGISSEGDLSFASEVSKISQEPRVSEDQPTADFKHMHLPGKKEPGDLSKEVALLDPGLLKLESCPSLSAAKEPQHDPEGAAISLEATEETVVSGSLEGLSEQARASDSDAKCISSDKATVMEEQESTHEIFKSKDSRNVESATECQLATLGPNPLCSSALPVNLSSHQDVVSTPWINDVRFPGRHSVLQLQNPETCEIFKREKNMGVFQKPLGLLIPHRYCKLHFNTLRGCERAQCKFVHVPEQGDEKICMDVFRKYISVNEQRLLHRAAYIFLEYYRKFPPGIHFSLQVLNDLLISLLKHCLLKEVFQVVQLSIMAKMLPALKILLKIFEYVAAMKLRNAVPALIEIFCKFIEAGMVPDPEHLNYIVKLLHQAQASQQEISAVLQAKSRLRVRQLKKNWKCDLDSALSEVETCKEKSDWTKLGNLYISIKMSCEEFADLQRFCACVAETLTEDYKEERPGVPFCEFAETVSKDPQYSEVDKTLLGRIGISAVYFYHRLLLWAKGRKVLDILYELKIHFTSLKGLTGPEKEAPRCQIVNVAAEIFIKSGSLDGAIWVLRESEWIINTPLWPCDRMDVLNRHNLLCTIAHEILGKNLYKQTFEVLRNLPSFQNSQEMMGVSQSSLLFNELLDACIESNSLGISSSVAEFMVAKSIPIDFSFLRRLITSLGRSCLWLKARAHYKSALSLGCYPPLEGNLHRKLLLVPSYLSEIEMLLAMEIFLVSNASGIQSAGMGAPTQVLQIVLKRCEESKSRSKDEYQAAVERLVMAARISDPKLFIKHMTVNINKEQVYSLEHCSALKWLKENMKWAGKVWLFTNH", "length": 1653, "header": "sp|E5FYH1-1|TOPZ1_MOUSE Isoform 1 of Protein TOPAZ1 OS=Mus musculus OX=10090 GN=Topaz1 PE=2 SV=1 CANONICAL=E5FYH1-1" }, "isoforms": [ { "isoform_ac": "E5FYH1-1", "url": "", "sequence": { "sequence": "MRPPATPPDPTKEPGCKGTTRGLRKRGLPLTPEPGEGGGCSLEARGCEEESRQKQRMVTQASGREETEGDKLAKENGKITEAPSDDPQPGTDLVRKTSITSSESLQTVECSEFQNMAFLQSLDKEELGEGIKRRMRIKKCKSLENPPLEITKNEATQNIKVEFQDELFKNTPKHSCNSLSPGVEKNCSFELHDYSFLHSEGCNNENNFEDKPHDVCLHTEENSLKLKKENLRNLAEKDDTRTTTKLLKTEKSVIASKLLLEESHLYQNKNNGLTSCLQSEKNKYSVEENNTGRKHRKKMKSGKEEKNINLTLSNVCNNSVLVLQENQMGMEGKEAETLEPKKSFLKALRKINHNTLPPVDHLCLPKTVGKTSSRHHINAMLQKTLESSLKEDIKNTSESLGCKRIEPEKYNKSMISSTVKSPSDGHHMEKRSPRGDLRSETEESKVSCCRTIPMTGKRVWPFYSCARISAQCWKKTSLSDLNYSLLGPLENVRQHDSIIHQMNQTHLPDSKLLQPSLTERTTESSRKEMYDSDLSCLSSVSSVESTVMDIKEAMSHDKKTKLEEPSRNGAEVVSNATEDTQLSNITQSLTGNKKRKGNLSKLNLTVASQESQETNNCANKTVHRKVCITKQTLVAPDLVKILNTGRLTNFKIPLLKNKTGKRGAVSARSSEREAYSPLELLDSLSGVEAKQNRNKENICTTSGPQSLNLHSCIAPGQASSHSFYNKNSCTSSSFTKKGYDNKACNHISEPGNIISNKESISMKIENNTFSCDLGYIDQSSFCSKKQEAFVPISSEISGRKMTKSISELKLGFPDILKAYEDDVLLIDVIQDDPELFGISSEGDLSFASEVSKISQEPRVSEDQPTADFKHMHLPGKKEPGDLSKEVALLDPGLLKLESCPSLSAAKEPQHDPEGAAISLEATEETVVSGSLEGLSEQARASDSDAKCISSDKATVMEEQESTHEIFKSKDSRNVESATECQLATLGPNPLCSSALPVNLSSHQDVVSTPWINDVRFPGRHSVLQLQNPETCEIFKREKNMGVFQKPLGLLIPHRYCKLHFNTLRGCERAQCKFVHVPEQGDEKICMDVFRKYISVNEQRLLHRAAYIFLEYYRKFPPGIHFSLQVLNDLLISLLKHCLLKEVFQVVQLSIMAKMLPALKILLKIFEYVAAMKLRNAVPALIEIFCKFIEAGMVPDPEHLNYIVKLLHQAQASQQEISAVLQAKSRLRVRQLKKNWKCDLDSALSEVETCKEKSDWTKLGNLYISIKMSCEEFADLQRFCACVAETLTEDYKEERPGVPFCEFAETVSKDPQYSEVDKTLLGRIGISAVYFYHRLLLWAKGRKVLDILYELKIHFTSLKGLTGPEKEAPRCQIVNVAAEIFIKSGSLDGAIWVLRESEWIINTPLWPCDRMDVLNRHNLLCTIAHEILGKNLYKQTFEVLRNLPSFQNSQEMMGVSQSSLLFNELLDACIESNSLGISSSVAEFMVAKSIPIDFSFLRRLITSLGRSCLWLKARAHYKSALSLGCYPPLEGNLHRKLLLVPSYLSEIEMLLAMEIFLVSNASGIQSAGMGAPTQVLQIVLKRCEESKSRSKDEYQAAVERLVMAARISDPKLFIKHMTVNINKEQVYSLEHCSALKWLKENMKWAGKVWLFTNH", "length": 1653, "header": "sp|E5FYH1-1|TOPZ1_MOUSE Isoform 1 of Protein TOPAZ1 OS=Mus musculus OX=10090 GN=Topaz1 PE=2 SV=1 CANONICAL=E5FYH1-1" }, "locus": { "chromosome": "9", "start_pos": 122631129, "end_pos": 122576411, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000178679", "url": "https://www.ensembl.org/id/ENSMUST00000178679" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000136304", "url": "https://www.ensembl.org/id/ENSMUSP00000136304" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 151, "start_aa": "Thr", "end_pos": 151, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr151", "evidence": [ { "id": "E5FYH1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=E5FYH1" }, { "id": "34418053", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34418053" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "TOPAZ1, a novel germ cell-specific expressed gene conserved during evolution across vertebrates.", "journal": "PLoS ONE", "date": "2011", "authors": "Baillet A, Le Bouffant R, Volff JN, Luangpraseuth A, Poumerol E, Thepot D, Pailhoux E, Livera G, Cotinot C, Mandon-Pepin B", "evidence": [ { "database": "UniProtKB", "id": "E5FYH1", "url": "https://www.uniprot.org/uniprot/E5FYH1" } ], "reference": [ { "type": "PubMed", "id": "22069478", "url": "https://glygen.org/publication/PubMed/22069478" } ] }, { "title": "TOPAZ1, a germ cell specific factor, is essential for male meiotic progression.", "journal": "Dev. Biol.", "date": "2015", "authors": "Luangpraseuth-Prosper A, Lesueur E, Jouneau L, Pailhoux E, Cotinot C, Mandon-Pepin B", "evidence": [ { "database": "UniProtKB", "id": "E5FYH1", "url": "https://www.uniprot.org/uniprot/E5FYH1" }, { "database": "RefSeq", "id": "NP_001186665", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186665" } ], "reference": [ { "type": "PubMed", "id": "26358182", "url": "https://glygen.org/publication/PubMed/26358182" } ] }, { "title": "O-GlcNAcylation Is Essential for Rapid Pomc Expression and Cell Proliferation in Corticotropic Tumor Cells.", "journal": "Endocrinology", "date": "2021", "authors": "Massman LJ, Pereckas M, Zwagerman NT, Olivier-Van Stichelen S", "evidence": [ { "database": "O-GlcNAc Database", "id": "E5FYH1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=E5FYH1" } ], "reference": [ { "type": "PubMed", "id": "34418053", "url": "https://glygen.org/publication/PubMed/34418053" } ] } ], "pathway": [ { "id": "mmu:671232", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:671232", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8N9V7-1", "protein_name": "Protein TOPAZ1", "gene_name": "TOPAZ1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRPPPLGPTTASGPEGNVRNLQKRQAPGPGAAGGCGPEAGGCRENKQKRRMVARATPGRGEVESDKSVAASGAGKAARRQVEGRRGPVSPSDSSDPRGLEAAKEAELPLQTERHTKEKRKVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQSLGKESIIEGIKRRIRNKKLKSLENPPLKITENEATQNIKVEFQDELYKNTPKYSCNILSPEVENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSKKENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEETENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEELSRRGSEVISNTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATSKDGQEANNSAGKTIHRKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNAKSSEREAYSPLELLDNLSGADVRQNRSKENVSMMMLGPQTLSIRNSVTPVQASSDSFYNKKSYSISPSFTKQGNNSKPSNHVSEPGNIVSNKEVASLTVENNAFSCDPGYVEKSPSFCCNEQETFRPVSSEVRGRKITKNFSEVGFPDILKAYEDDVLLIDVIQDDPDLFGVSNEGELSFTSEVPKISQEPNVAGEHQSTDSKYMETPVKKEPSDDLRELPVLDCGWIKPDICASNSAESEIKRDPKDVNTSLGEVANETSENETLGDFSEQIKGSDLDEKHRFTDKVITKEEKENIYEVCKSKDSRNADFMVGECQFAVPVPKPLCLLVPPLNLSGRQEDTILNTWMNDFRFLGKHSVLKLQNPETCEIFKREKNVGVFQKSLGLMIPYKYCKFHFNTLRGCERPLCKFAHVPEQGDEKVCMDVFKKYININELCLLQRAVNIFMEYYRKFPPGVYFDLQVLNDLLNSLLKHCLLKEVFQIVNLSIMVKMLPSLKILLNIFEYVATMKLRNAVPALIDIFCKLVEAGMVLDPEHFNYIVKLLYQVQASKQEITAVLEMKSRLQMRRFKKNWKCDLDSALNKLEHCKEKGDWTKLGKLYINVKMGCEKFADFQTFCACIAETLTKNYEDERPDIPFCEFAETVSKDPQNSKVDKGVLGRIGISAMYFYHKLLQWSKGRKVLEKLYELKIHFTSLKGLIGPEKLASRCQIVNVAAEIFLKSGSLDGAIWVMRESEWIINTPLWPCDRLDVLNRHNLLCTIAHEILAKSLYRQTFEVLQNLPGFQNSQETVEVSQYSLLFNKLLGSCIESSSLGMSSSVAEFMISKSIPIDFSFLRRLITSLGRSRLWLKARAHYKSALSLGCYPPLEGNLYRKLLLIPSYLSEIEMLLAIEIFMVSNASSIQSPGTSTQILQIVLKRCEDNQSRSNDDYQAAVERLIMAARISDPKLFVKHMTVNVNKEQVYSLEHCSALKWLKENMKWAGKVWLFSNH", "length": 1692 }, "evidence": [ { "id": "45238578", "url": "http://www.informatics.jax.org/homology/45238578", "database": "MGI" }, { "id": "E5FYH1", "url": "https://omabrowser.org/oma/group/E5FYH1/", "database": "OMA" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E5FYH1", "url": "https://www.uniprot.org/uniprot/E5FYH1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E5FYH1", "url": "https://www.uniprot.org/uniprot/E5FYH1" } ], "pmid": "" }, { "name": "ectopic germ cell programmed cell death", "id": "GO:0035234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035234", "evidence": [ { "database": "UniProtKB", "id": "E5FYH1", "url": "https://www.uniprot.org/uniprot/E5FYH1" } ], "pmid": "" }, { "name": "ncRNA transcription", "id": "GO:0098781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098781", "evidence": [ { "database": "UniProtKB", "id": "E5FYH1", "url": "https://www.uniprot.org/uniprot/E5FYH1" } ], "pmid": "" }, { "name": "spermatocyte division", "id": "GO:0048137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048137", "evidence": [ { "database": "UniProtKB", "id": "E5FYH1", "url": "https://www.uniprot.org/uniprot/E5FYH1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1559, "end_pos": 1561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 503, "end_pos": 505, "annotation": "n_glycosylation_sequon" }, { "start_pos": 575, "end_pos": 577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 619, "end_pos": 621, "annotation": "n_glycosylation_sequon" }, { "start_pos": 657, "end_pos": 659, "annotation": "n_glycosylation_sequon" }, { "start_pos": 766, "end_pos": 768, "annotation": "n_glycosylation_sequon" }, { "start_pos": 998, "end_pos": 1000, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }