{
    "uniprot_canonical_ac": "D4AAV6-1",
    "uniprot_ac": "D4AAV6",
    "uniprot_id": "D4AAV6_RAT",
    "mass": {
        "chemical_mass": 30000.0,
        "monoisotopic_mass": 30000.0
    },
    "refseq": {
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        "name": "programmed cell death 1 ligand 2 precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101052"
    },
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            "name": "Pdcd1lg2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/D4AAV6",
            "id": "D4AAV6"
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            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101052",
            "id": "NP_001101052"
        },
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            "type": "synonym",
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            "id": "NP_001101052"
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            "id": "NP_001101052"
        },
        {
            "name": "Programmed cell death 1 ligand 2",
            "resource": "UniProtKB",
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            "url": "",
            "id": "D4AAV6"
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            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101052",
            "id": "NP_001101052"
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    ],
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        {
            "disease_id": "DOID:2957",
            "recommended_name": {
                "id": "DOID:2957",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:2957",
                "name": "pulmonary tuberculosis",
                "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "2957",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:2957"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
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                    "url": "https://www.uniprot.org/uniprot/D4AAV6"
                }
            ],
            "common_name": "Rat"
        }
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            "name": "Pdcd1lg2",
            "url": "https://www.uniprot.org/uniprot/D4AAV6",
            "locus": {
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                "end_pos": 227158941,
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                "evidence": [
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                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000016136",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000016136"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000016136",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000016136",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd20983",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20983",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "309304",
            "url": "https://www.ncbi.nlm.nih.gov/gene/309304",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR003599",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013162",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013162",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013783",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036179",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
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            "id": "rno:309304",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:309304",
            "database": "KEGG Pathway",
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            ]
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        {
            "id": "EVSWPDI",
            "url": "https://omabrowser.org/oma/group/EVSWPDI/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5315576at2759",
            "url": "http://www.orthodb.org/?query=5315576at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR25466",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25466",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR25466:SF1",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25466:SF1",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF08205",
            "url": "http://pfam.xfam.org/family/PF08205",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-389948",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-389948",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
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            "id": "NP_001101052",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101052",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1306403",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1306403",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "D4AAV6",
            "url": "https://www.uniprot.org/uniprot/D4AAV6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D4AAV6-1",
            "url": "https://www.uniprot.org/uniprot/D4AAV6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
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        "length": 268,
        "header": "tr|D4AAV6-1|D4AAV6_RAT Isoform 1 of Programmed cell death 1 ligand 2  OS=Rattus norvegicus OX=10116 GN=Pdcd1lg2 PE=4 SV=2 CANONICAL=D4AAV6-1"
    },
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        {
            "isoform_ac": "D4AAV6-1",
            "url": "",
            "sequence": {
                "sequence": "MLLLLLILNLSSQLHHIAALFTVTAPKEVYTVDFGSSVSLECDFDRRECTELEGIRASLQKVENDTSSQSQRATLLEELLPLGKASFHIPSVQVRDSGQYRCLVICGAAWDYKYLTVKVKASYVRIDTGILEVPGTGEVQLICQARGYPLAEVSWQNVSVPANTSHIRTPEGLYQVTSVLRLKPQPNRNFSCMFWNAHMKELTSAIIDPLSWMEPKVPRTRSLHAFIPACTVALIFLATVIAQRKRLWGKLYSRKRSEPAVLGVGKIQ",
                "length": 268,
                "header": "tr|D4AAV6-1|D4AAV6_RAT Isoform 1 of Programmed cell death 1 ligand 2  OS=Rattus norvegicus OX=10116 GN=Pdcd1lg2 PE=4 SV=2 CANONICAL=D4AAV6-1"
            },
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                "chromosome": "1",
                "start_pos": 227223358,
                "end_pos": 227177916,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000021614.7",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000021614.7"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000021615.6",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000021615.6"
                    }
                ]
            }
        }
    ],
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    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
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        {
            "id": "rno:309304",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:309304",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-389948",
            "name": "PD-1 signaling",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-389948",
            "resource": "Reactome",
            "description": "PD-1 signaling"
        }
    ],
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        {
            "uniprot_canonical_ac": "Q9BQ51-1",
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            "gene_name": "PDCD1LG2",
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                "length": 273
            },
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                    "id": "45239358",
                    "url": "http://www.informatics.jax.org/homology/45239358",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9WUL5-1",
            "protein_name": "Programmed cell death 1 ligand 2",
            "gene_name": "Pdcd1lg2",
            "tax_id": 10090,
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                "length": 247
            },
            "evidence": [
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                    "id": "45239358",
                    "url": "http://www.informatics.jax.org/homology/45239358",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        }
    ],
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        "categories": [
            {
                "name": "Biological Process",
                "total": 9,
                "go_terms": [
                    {
                        "name": "negative regulation of interleukin-10 production",
                        "id": "GO:0032693",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032693",
                        "evidence": [
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                                "id": "D4AAV6",
                                "url": "https://www.uniprot.org/uniprot/D4AAV6"
                            }
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                    },
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955",
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                                "id": "D4AAV6",
                                "url": "https://www.uniprot.org/uniprot/D4AAV6"
                            }
                        ],
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                    },
                    {
                        "name": "cell surface receptor signaling pathway",
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166",
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                                "id": "D4AAV6",
                                "url": "https://www.uniprot.org/uniprot/D4AAV6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "T cell costimulation",
                        "id": "GO:0031295",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031295",
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                                "id": "D4AAV6",
                                "url": "https://www.uniprot.org/uniprot/D4AAV6"
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                    },
                    {
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                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of T cell proliferation",
                        "id": "GO:0042130",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042130",
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                                "id": "D4AAV6",
                                "url": "https://www.uniprot.org/uniprot/D4AAV6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222",
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                                "database": "UniProtKB",
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                                "url": "https://www.uniprot.org/uniprot/D4AAV6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of T cell proliferation",
                        "id": "GO:0042102",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042102",
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                                "database": "UniProtKB",
                                "id": "D4AAV6",
                                "url": "https://www.uniprot.org/uniprot/D4AAV6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of activated T cell proliferation",
                        "id": "GO:0046007",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046007",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D4AAV6",
                                "url": "https://www.uniprot.org/uniprot/D4AAV6"
                            }
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                        "pmid": ""
                    }
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            {
                "name": "Cellular Component",
                "total": 1,
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                    {
                        "name": "external side of plasma membrane",
                        "id": "GO:0009897",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897",
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                                "database": "UniProtKB",
                                "id": "D4AAV6",
                                "url": "https://www.uniprot.org/uniprot/D4AAV6"
                            }
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                        "pmid": ""
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                ]
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        ]
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    "ptm_annotation": [],
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    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
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