{
    "uniprot_canonical_ac": "D4A8I5-1",
    "uniprot_ac": "D4A8I5",
    "uniprot_id": "D4A8I5_RAT",
    "mass": {
        "chemical_mass": 116509.0,
        "monoisotopic_mass": 116509.0
    },
    "refseq": {
        "ac": "NP_001128505",
        "name": "tripartite motif-containing protein 16",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128505"
    },
    "gene_names": [
        {
            "name": "Fbxw10",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/D4A8I5",
            "id": "D4A8I5"
        },
        {
            "name": "Trim16",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/D4A8I5",
            "id": "D4A8I5"
        },
        {
            "name": "Fbxw10",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/D4A8I5",
            "id": "D4A8I5"
        },
        {
            "name": "Trim16",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128505",
            "id": "NP_001128505"
        },
        {
            "name": "Trim16",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/D4A8I5",
            "id": "D4A8I5"
        }
    ],
    "protein_names": [
        {
            "name": "F-box and WD repeat domain containing 10",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "D4A8I5"
        },
        {
            "name": "tripartite motif protein 16",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128505",
            "id": "NP_001128505"
        },
        {
            "name": "tripartite motif-containing protein 16",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128505",
            "id": "NP_001128505"
        }
    ],
    "function": [
        {
            "annotation": "A thermosensitive, reactive oxygen species-responsive, MR409-encapsulated hydrogel ameliorates disc degeneration in rats by inhibiting the secretory autophagy pathway. Publication Status: Online-Only",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001128505",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128505"
                },
                {
                    "database": "PubMed",
                    "id": "33391467",
                    "url": "https://glygen.org/publication/PubMed/33391467"
                }
            ]
        },
        {
            "annotation": "Tripartite motif-containing protein 16 protects against myocardial ischemia/reperfusion injury by affecting the Keap1/Nrf2 axis.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001128505",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128505"
                },
                {
                    "database": "PubMed",
                    "id": "34436665",
                    "url": "https://glygen.org/publication/PubMed/34436665"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "D4A8I5",
                    "url": "https://www.uniprot.org/uniprot/D4A8I5"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Fbxw10",
            "url": "https://www.uniprot.org/uniprot/D4A8I5",
            "locus": {
                "chromosome": "10",
                "start_pos": 47551907,
                "end_pos": 47486297,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000003287",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000003287"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000003219",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000003219",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "ENSRNOG00000003287",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000003287",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd00200",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd12890",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12890",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd19769",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19769",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd19839",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19839",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd22136",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22136",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "303214",
            "url": "https://www.ncbi.nlm.nih.gov/gene/303214",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000315",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001680",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001810",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001870",
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            "database": "InterPro",
            "categories": [
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            ]
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        {
            "id": "IPR003877",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR003879",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR006574",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013320",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR015943",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR020472",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036047",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036322",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR043136",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:303214",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:303214",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "CRALKSC",
            "url": "https://omabrowser.org/oma/group/CRALKSC/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5299679at2759",
            "url": "http://www.orthodb.org/?query=5299679at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR19872",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19872",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR19872:SF7",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19872:SF7",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR25465",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR25465:SF10",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF10",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00400",
            "url": "http://pfam.xfam.org/family/PF00400",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00622",
            "url": "http://pfam.xfam.org/family/PF00622",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00643",
            "url": "http://pfam.xfam.org/family/PF00643",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF13765",
            "url": "http://pfam.xfam.org/family/PF13765",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1309749",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1309749",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "1563889",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1563889",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A8I6GI85",
            "url": "https://www.uniprot.org/uniprot/A0A8I6GI85",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6GI85-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6GI85-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3ZW47",
            "url": "https://www.uniprot.org/uniprot/D3ZW47",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3ZW47-1",
            "url": "https://www.uniprot.org/uniprot/D3ZW47-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D4A8I5",
            "url": "https://www.uniprot.org/uniprot/D4A8I5",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D4A8I5-1",
            "url": "https://www.uniprot.org/uniprot/D4A8I5-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MENTEQKLRQSPYFCCEKGSNWVPVCHKCEACVLAWKIFATKEWFRRVNDTSQRRFLVSILVQLNSLYLLQYFQNILETTQGKDFIYNRSRIKLNRKGGKEEEVVKSSLNQMLDKTVESKMKEILCWFGNSTHRTKANYTLLLLQMCDSNLLLTAANVIRVLFMKEWNNISGLREDASNVIFFPEKTYNATHDISYISWSARPKPVSFPMSRHLGNKLGTENVDKGTTEAKAKSSLHVISEINKEIFGRGGTSRLGDEPCNLLLSLDHVQLLSSGFSKYRDFIRDLPLHLSKYILRMLDKNSLNKCVFVSQHWATLVQQVKVDQSMHSFIQNQITLLQGSYTRGIDPNYANKVSIPVPKIVDDGKRSRSKNQKWKLRTKNDYNLWTAYQNQETQLIQMEERNVFCGTYNIRILSDTFDQNRIIHYSGGDLMAVSSNRKIHLLDIMQVRELPIEFRGHAGSIRALFLSEEDNILLSGSYDLSIRYWDIKTGACIRIFYGHQGTITCLDLYKNRLVSGAKDGQVKEWDIETGKCLKTFKHKDPILAARISETYIVSSCERGIVKVWHVVTAQLQKTLTGHEGAVKCLFFNQWHLVSGGADGLVMAWSMVGKYERCLMAFKHPKEVLQVSLLYLRVISACGDGKIRIYNFLNGNCLKVIKVDARGDPVLSFFYQGNRWVVGRMVVHTDSSILVFQFENVKWQYSSDKNKTKKNKDKEEEREETSLGDTHSKSSLQVHSLRDSGSIKQEFSKSRVLLKQTRNLSSDDVENPGSEASYPLQKSGKVPITPDRFLLTLNALQAHNSEEFAYPHRPRIQVIDAWGLSIPYQRKVLTFKGKSVQHAVDQLRSSNLLTDVKQTNIPLEIRKLQPDLKKSLHSPRVQASIPQPSLIRPKVSDSLRGDEHLTSSIDGRAGPLTSLQVIKPNRMLAPRGGTTTLSLKKERPRFYTTLNPLRMNTGFMLLTVKEEKEFAEAKIKEYEASVSTKEVDPGKASKAAWIRKIKGLPIDHFLKEGKTAAPELGQNVFI",
        "length": 1021,
        "header": "tr|D4A8I5-1|D4A8I5_RAT Isoform 1 of F-box and WD repeat domain containing 10  OS=Rattus norvegicus OX=10116 GN=Fbxw10 PE=4 SV=4 CANONICAL=D4A8I5-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A8I6GI85-1",
            "url": "",
            "sequence": {
                "sequence": "MAELDLIAPGPLTGVTVHPLAPLGPDPGSAIPIGKEDVDLLSKPGEETQGQGDLAKLGAPGDEEEGQILCDFCLGASRVRAVKSCLTCMVNYCEEHLRPHQENSKLHSHQLTEPTKDQDLRTCPAHHSPLVSFCHTHQQCICQECGTGEHRGDSTVSLDAARRSKEADLRCMQLDLEQKLKLNENAIARLQANHKSVLVSVSEVKVVAEEKFGELLAAVRKAQTDVMLFLEEKEQAALNQVNGIKTHLEHRSIEMEKNKQELEKLASISNTVLFLEEYCKLKKTEDTAFPSVYIGLKDKLSGIRKVITESTLNLIQLLESYKEKLQEFSREEEYDIRTQVSAIVQRKYRTSKPEPRTRDEFLQYACDITFDPDTAHRYLRLQEDNRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEISGGGIYVGLTCKGIDRKGEERNSCISGNSFSWSIHWSGKEFTAWHSDTETPLKASVKTPPM",
                "length": 489,
                "header": "tr|A0A8I6GI85-1|D4A8I5_RAT Computationally mapped isoform of F-box and WD repeat domain containing 10  OS=Rattus norvegicus OX=10116 GN=Fbxw10 PE=4 SV=1 CANONICAL=D4A8I5-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 47517603,
                "end_pos": 47486359,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000099929.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000099929.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000089597.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000089597.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D3ZW47-1",
            "url": "",
            "sequence": {
                "sequence": "MAELDLIAPGPLTGVTVHPLAPLGPDPGSAIPIGKEDVDLLSKPGEETQGQGDLAKLGAPGDEEEGQILCDFCLGASRVRAVKSCLTCMVNYCEEHLRPHQENSKLHSHQLTEPTKDQDLRTCPAHHSPLVSFCHTHQQCICQECGTGEHRGDSTVSLDAARRSKEADLRCMQLDLEQKLKLNENAIARLQANHKSVLVSVSEVKVVAEEKFGELLAAVRKAQTDVMLFLEEKEQAALNQVNGIKTHLEHRSIEMEKNKQELEKLASISNTVLFLEEYCKLKKTEDTAFPSVYIGLKDKLSGIRKVITESTLNLIQLLESYKEKLQEFSREEEYDIRTQVSAIVQRKYRTSKPEPRTRDEFLQYACDITFDPDTAHRYLRLQEDNRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEISGGGIYVGLTCKGIDRKGEERNSCISGNSFSWSIHWSGKEFTAWHSDTETPLKASPFRRLGIYVNFPGGTLSFYGVEYDAMTLIQKFDCKFSEPLYAAFWLSKKENTIRIVDLGEEPEKPAVPSVEAAP",
                "length": 557,
                "header": "tr|D3ZW47-1|D3ZW47_RAT Computationally mapped isoform of F-box and WD repeat domain containing 10  OS=Rattus norvegicus OX=10116 GN=Trim16 PE=4 SV=1 CANONICAL=D4A8I5-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 47506902,
                "end_pos": 47486359,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000065335.4",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000065335.4"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000063404.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000063404.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D4A8I5-1",
            "url": "",
            "sequence": {
                "sequence": "MENTEQKLRQSPYFCCEKGSNWVPVCHKCEACVLAWKIFATKEWFRRVNDTSQRRFLVSILVQLNSLYLLQYFQNILETTQGKDFIYNRSRIKLNRKGGKEEEVVKSSLNQMLDKTVESKMKEILCWFGNSTHRTKANYTLLLLQMCDSNLLLTAANVIRVLFMKEWNNISGLREDASNVIFFPEKTYNATHDISYISWSARPKPVSFPMSRHLGNKLGTENVDKGTTEAKAKSSLHVISEINKEIFGRGGTSRLGDEPCNLLLSLDHVQLLSSGFSKYRDFIRDLPLHLSKYILRMLDKNSLNKCVFVSQHWATLVQQVKVDQSMHSFIQNQITLLQGSYTRGIDPNYANKVSIPVPKIVDDGKRSRSKNQKWKLRTKNDYNLWTAYQNQETQLIQMEERNVFCGTYNIRILSDTFDQNRIIHYSGGDLMAVSSNRKIHLLDIMQVRELPIEFRGHAGSIRALFLSEEDNILLSGSYDLSIRYWDIKTGACIRIFYGHQGTITCLDLYKNRLVSGAKDGQVKEWDIETGKCLKTFKHKDPILAARISETYIVSSCERGIVKVWHVVTAQLQKTLTGHEGAVKCLFFNQWHLVSGGADGLVMAWSMVGKYERCLMAFKHPKEVLQVSLLYLRVISACGDGKIRIYNFLNGNCLKVIKVDARGDPVLSFFYQGNRWVVGRMVVHTDSSILVFQFENVKWQYSSDKNKTKKNKDKEEEREETSLGDTHSKSSLQVHSLRDSGSIKQEFSKSRVLLKQTRNLSSDDVENPGSEASYPLQKSGKVPITPDRFLLTLNALQAHNSEEFAYPHRPRIQVIDAWGLSIPYQRKVLTFKGKSVQHAVDQLRSSNLLTDVKQTNIPLEIRKLQPDLKKSLHSPRVQASIPQPSLIRPKVSDSLRGDEHLTSSIDGRAGPLTSLQVIKPNRMLAPRGGTTTLSLKKERPRFYTTLNPLRMNTGFMLLTVKEEKEFAEAKIKEYEASVSTKEVDPGKASKAAWIRKIKGLPIDHFLKEGKTAAPELGQNVFI",
                "length": 1021,
                "header": "tr|D4A8I5-1|D4A8I5_RAT Isoform 1 of F-box and WD repeat domain containing 10  OS=Rattus norvegicus OX=10116 GN=Fbxw10 PE=4 SV=4 CANONICAL=D4A8I5-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 47551854,
                "end_pos": 47513527,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000004390.7",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000004390.7"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000004390.7",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000004390.7"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "A thermosensitive, reactive oxygen species-responsive, MR409-encapsulated hydrogel ameliorates disc degeneration in rats by inhibiting the secretory autophagy pathway.",
            "journal": "Theranostics",
            "date": "2021",
            "authors": "Zheng Q, Shen H, Tong Z, Cheng L, Xu Y, Feng Z, Liao S, Hu X, Pan Z, Mao Z, Wang Y",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001128505",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128505"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "33391467",
                    "url": "https://glygen.org/publication/PubMed/33391467"
                }
            ]
        },
        {
            "title": "Tripartite motif-containing protein 16 protects against myocardial ischemia/reperfusion injury by affecting the Keap1/Nrf2 axis.",
            "journal": "Cell and tissue research",
            "date": "2021",
            "authors": "Cui Q, Yan L",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001128505",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128505"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "34436665",
                    "url": "https://glygen.org/publication/PubMed/34436665"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:303214",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:303214",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q99PP9-1",
            "protein_name": "Tripartite motif-containing protein 16",
            "gene_name": "Trim16",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MAELDLIAPGPLTGVTAHPLAPLGPDPVSAIPVEKEDADPLSKSGEETQEQGHDPAELGAPGEEDQILCDFCLGASRVRAVKSCLTCMVNYCEEHLRPHQENSKLHSHQLTEPAKDQDLRTCPAHHSPLVSFCHTHQQCICQECGEGEHRGDSTVSLDAARRNKEVDLRCMQLDLEQKLKLNENAIARLQANHKSVLVSVSEVKVVAEEKFGELLAAVRKAQADVMVFLEEKEQAALNQVNSIKTHLEHRSLEMEKSKQELERLAAISNTVLFLEEYCKLKKTEDTASPSIYIGLKDKLSGIRKVITDSTLNLIQLLESYKEKLQEFSREEEYDIRTQVSAIVQRKYRTSKPEPRTRDEFLQYACDITFDPDTAHRYLRLQEDNRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVELSGGGTYVGLTCKGIDRKGEERNSCISGNSFSWSIHWNGKEFTAWHSDTETPLKVSPFRRLGIYVNFPGGILSFYGVEYDAMTLIHKFDCKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAGSSVEAAP",
                "length": 556
            },
            "evidence": [
                {
                    "id": "45229937",
                    "url": "http://www.informatics.jax.org/homology/45229937",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 4,
                "go_terms": [
                    {
                        "name": "DNA binding",
                        "id": "GO:0003677",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D4A8I5",
                                "url": "https://www.uniprot.org/uniprot/D4A8I5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "interleukin-1 binding",
                        "id": "GO:0019966",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019966",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D4A8I5",
                                "url": "https://www.uniprot.org/uniprot/D4A8I5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "NACHT domain binding",
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032089",
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                            {
                                "database": "UniProtKB",
                                "id": "D4A8I5",
                                "url": "https://www.uniprot.org/uniprot/D4A8I5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "zinc ion binding",
                        "id": "GO:0008270",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D4A8I5",
                                "url": "https://www.uniprot.org/uniprot/D4A8I5"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D4A8I5",
                                "url": "https://www.uniprot.org/uniprot/D4A8I5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "PML body",
                        "id": "GO:0016605",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D4A8I5",
                                "url": "https://www.uniprot.org/uniprot/D4A8I5"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 7,
                "go_terms": [
                    {
                        "name": "response to retinoic acid",
                        "id": "GO:0032526",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032526",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D4A8I5",
                                "url": "https://www.uniprot.org/uniprot/D4A8I5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of DNA-templated transcription",
                        "id": "GO:0045893",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D4A8I5",
                                "url": "https://www.uniprot.org/uniprot/D4A8I5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to growth hormone",
                        "id": "GO:0060416",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060416",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D4A8I5",
                                "url": "https://www.uniprot.org/uniprot/D4A8I5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of interleukin-1 beta production",
                        "id": "GO:0032731",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032731",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D4A8I5",
                                "url": "https://www.uniprot.org/uniprot/D4A8I5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to organophosphorus",
                        "id": "GO:0046683",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046683",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D4A8I5",
                                "url": "https://www.uniprot.org/uniprot/D4A8I5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of retinoic acid receptor signaling pathway",
                        "id": "GO:0048386",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048386",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D4A8I5",
                                "url": "https://www.uniprot.org/uniprot/D4A8I5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of keratinocyte differentiation",
                        "id": "GO:0045618",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045618",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D4A8I5",
                                "url": "https://www.uniprot.org/uniprot/D4A8I5"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
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    "pro_annotation": [],
    "site_annotation": [
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            "start_pos": 130,
            "end_pos": 132,
            "annotation": "n_glycosylation_sequon"
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        {
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            "annotation": "n_glycosylation_sequon"
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        {
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            "annotation": "n_glycosylation_sequon"
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            "end_pos": 191,
            "annotation": "n_glycosylation_sequon"
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            "start_pos": 49,
            "end_pos": 51,
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            "start_pos": 705,
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            "end_pos": 760,
            "annotation": "n_glycosylation_sequon"
        },
        {
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            "end_pos": 90,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "section_stats": [
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        {
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        {
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        {
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}