{ "uniprot_canonical_ac": "D4A857-1", "uniprot_ac": "D4A857", "uniprot_id": "D4A857_RAT", "mass": { "chemical_mass": 116650.0, "monoisotopic_mass": 116650.0 }, "refseq": {}, "gene_names": [ { "name": "Ipo9", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/D4A857", "id": "D4A857" } ], "protein_names": [ { "name": "Importin 9", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "D4A857" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A857", "url": "https://www.uniprot.org/uniprot/D4A857" } ], "common_name": "Rat" } ], "gene": [ { "name": "Ipo9", "url": "https://www.uniprot.org/uniprot/D4A857", "locus": { "chromosome": "13", "start_pos": 46813171, "end_pos": 46862673, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000007418", "url": "https://www.ensembl.org/id/ENSRNOG00000007418" } ] } } ], "crossref": [ { "id": "ENSRNOG00000007418", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000007418", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "D4A857", "url": "https://www.ebi.ac.uk/intact/interactors/id:D4A857*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:304817", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:304817", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CLRAPPV", "url": "https://omabrowser.org/oma/group/CLRAPPV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "2908261at2759", "url": "http://www.orthodb.org/?query=2908261at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10997", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10997", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10997:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10997:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03810", "url": "http://pfam.xfam.org/family/PF03810", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "1310537", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1310537", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "D4A857", "url": "https://www.uniprot.org/uniprot/D4A857", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D4A857-1", "url": "https://www.uniprot.org/uniprot/D4A857-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAAAGAASGLPGPVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSAIAHWDWPEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTDTQMPLVAPVILPEMYKIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPVVQQFTEAFVQALQMPDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQILPIVWNTLTESAALYPFLRTRRTEVNYTEEVEDPVDSDGEVLGFENLVFSIFEFVHALLENSKFKSTVKKALPELIYYIILYMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVATDFQNESAVALATAATRHLQEAEQTKASGTEHWWKIHEACMLALGSVKSIITDSVKNGRIHFDMHGFLTNVILADLNLSASPFLLGRALWAASRFTVAMSPELIQQFLQATVSGLHETQPPSVRISAVRAIWGYCDQLKVSESTHVLQPFLPSILDGLIHLAAQFSSEVLNLVMETLCIVCTVDPEFTASVESKICPFTIAIFLKYSNDPVVASLAQDIFKELSQIEACQGPMQMRLIPTLVSIMQAPADKIPAGLCATAIDILTTVVRNTKPPLSQLLICQAFPAVAQCTLHTDDNATMQNGGECLRAYVSVTLEQVAQWHDEQGHNGLWYVMQVVSQLLDPRTSEFTAAFVGRLVSTLISKAGRELGENLDQILRAILSKMQQAETLSVMQSLIMVFAHLVHTQLEPLLEFLCSLPGPTGKPALEFVMAEWTSRQHLFYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWTNIPLLVKILKLIINELSNVMEANAARQATPAEWNQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDALKDPLYQIDLQAYLTDFLCQFAQQPCYIMFSCHLNDTERRVLQTIGI", "length": 1046, "header": "tr|D4A857-1|D4A857_RAT Isoform 1 of Importin 9 OS=Rattus norvegicus OX=10116 GN=Ipo9 PE=4 SV=3 CANONICAL=D4A857-1" }, "isoforms": [ { "isoform_ac": "D4A857-1", "url": "", "sequence": { "sequence": "MAAAAAAGAASGLPGPVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSAIAHWDWPEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTDTQMPLVAPVILPEMYKIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPVVQQFTEAFVQALQMPDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQILPIVWNTLTESAALYPFLRTRRTEVNYTEEVEDPVDSDGEVLGFENLVFSIFEFVHALLENSKFKSTVKKALPELIYYIILYMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVATDFQNESAVALATAATRHLQEAEQTKASGTEHWWKIHEACMLALGSVKSIITDSVKNGRIHFDMHGFLTNVILADLNLSASPFLLGRALWAASRFTVAMSPELIQQFLQATVSGLHETQPPSVRISAVRAIWGYCDQLKVSESTHVLQPFLPSILDGLIHLAAQFSSEVLNLVMETLCIVCTVDPEFTASVESKICPFTIAIFLKYSNDPVVASLAQDIFKELSQIEACQGPMQMRLIPTLVSIMQAPADKIPAGLCATAIDILTTVVRNTKPPLSQLLICQAFPAVAQCTLHTDDNATMQNGGECLRAYVSVTLEQVAQWHDEQGHNGLWYVMQVVSQLLDPRTSEFTAAFVGRLVSTLISKAGRELGENLDQILRAILSKMQQAETLSVMQSLIMVFAHLVHTQLEPLLEFLCSLPGPTGKPALEFVMAEWTSRQHLFYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWTNIPLLVKILKLIINELSNVMEANAARQATPAEWNQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDALKDPLYQIDLQAYLTDFLCQFAQQPCYIMFSCHLNDTERRVLQTIGI", "length": 1046, "header": "tr|D4A857-1|D4A857_RAT Isoform 1 of Importin 9 OS=Rattus norvegicus OX=10116 GN=Ipo9 PE=4 SV=3 CANONICAL=D4A857-1" }, "locus": { "chromosome": "13", "start_pos": 46862646, "end_pos": 46814182, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000011105.6", "url": "https://www.ensembl.org/id/ENSRNOT00000011105.6" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000011105.5", "url": "https://www.ensembl.org/id/ENSRNOP00000011105.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "rno:304817", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:304817", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "D4A857", "url": "https://www.uniprot.org/uniprot/D4A857" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D4A857", "url": "https://www.uniprot.org/uniprot/D4A857" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "D4A857", "url": "https://www.uniprot.org/uniprot/D4A857" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "D4A857", "url": "https://www.uniprot.org/uniprot/D4A857" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "D4A857", "url": "https://www.uniprot.org/uniprot/D4A857" } ], "pmid": "" }, { "name": "nuclear import signal receptor activity", "id": "GO:0061608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061608", "evidence": [ { "database": "UniProtKB", "id": "D4A857", "url": "https://www.uniprot.org/uniprot/D4A857" } ], "pmid": "" }, { "name": "histone chaperone activity", "id": "GO:0140713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140713", "evidence": [ { "database": "UniProtKB", "id": "D4A857", "url": "https://www.uniprot.org/uniprot/D4A857" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "D4A857", "url": "https://www.uniprot.org/uniprot/D4A857" } ], "pmid": "" }, { "name": "proteasome localization", "id": "GO:0031144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031144", "evidence": [ { "database": "UniProtKB", "id": "D4A857", "url": "https://www.uniprot.org/uniprot/D4A857" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1034, "end_pos": 1036, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 712, "end_pos": 714, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }