{ "uniprot_canonical_ac": "D4A7M5-1", "uniprot_ac": "D4A7M5", "uniprot_id": "D4A7M5_RAT", "mass": { "chemical_mass": 37167.0, "monoisotopic_mass": 37167.0 }, "refseq": {}, "gene_names": [ { "name": "Neurod4", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/D4A7M5", "id": "D4A7M5" } ], "protein_names": [ { "name": "Neurogenic differentiation factor", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "D4A7M5" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "common_name": "Rat" } ], "gene": [ { "name": "Neurod4", "url": "https://www.uniprot.org/uniprot/D4A7M5", "locus": { "chromosome": "7", "start_pos": 7090045, "end_pos": 7102030, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000008449", "url": "https://www.ensembl.org/id/ENSRNOG00000008449" } ] } } ], "crossref": [ { "id": "ENSRNOG00000008449", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000008449", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19721", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19721", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016637", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016637", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YELPIDM", "url": "https://omabrowser.org/oma/group/YELPIDM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "2915590at2759", "url": "http://www.orthodb.org/?query=2915590at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19290", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19290", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19290:SF86", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19290:SF86", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "http://pfam.xfam.org/family/PF00010", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF12533", "url": "http://pfam.xfam.org/family/PF12533", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "XP_006240880", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006240880", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1310434", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1310434", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D4A7M5-1", "url": "https://www.uniprot.org/uniprot/D4A7M5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKMYMKSKDMVELVNTQSWMDKGLSSQNEMEEQERRPGSYGMLGTLMEEHDSIEEEEEEEEDGDKPKRRGPKKKKMTKARLERFRARRVKANARERTRMHGLNDALDNLRRVMPCYSKTQKLSKIETLRLARNYIWALSEVLETGQTLEGKGFVEMLCKGLSQPTSNLVAGCLQLGPQSALLEKREEKSPICDSTVSVHSFNYQSPGLPSPPYGHMETHPLHLKPQPFKSLGDSFGSHPPDCSTPPYEGPLTPPLSISGNFSLKQEGSPDLEKSYNFMPHYTSASVSSGHVHSTPFQTGTPRYDVPVDLTYDSYPHHGIGTQINTIFSD", "length": 330, "header": "tr|D4A7M5-1|D4A7M5_RAT Isoform 1 of Neurogenic differentiation factor OS=Rattus norvegicus OX=10116 GN=Neurod4 PE=4 SV=1 CANONICAL=D4A7M5-1" }, "isoforms": [ { "isoform_ac": "D4A7M5-1", "url": "", "sequence": { "sequence": "MAKMYMKSKDMVELVNTQSWMDKGLSSQNEMEEQERRPGSYGMLGTLMEEHDSIEEEEEEEEDGDKPKRRGPKKKKMTKARLERFRARRVKANARERTRMHGLNDALDNLRRVMPCYSKTQKLSKIETLRLARNYIWALSEVLETGQTLEGKGFVEMLCKGLSQPTSNLVAGCLQLGPQSALLEKREEKSPICDSTVSVHSFNYQSPGLPSPPYGHMETHPLHLKPQPFKSLGDSFGSHPPDCSTPPYEGPLTPPLSISGNFSLKQEGSPDLEKSYNFMPHYTSASVSSGHVHSTPFQTGTPRYDVPVDLTYDSYPHHGIGTQINTIFSD", "length": 330, "header": "tr|D4A7M5-1|D4A7M5_RAT Isoform 1 of Neurogenic differentiation factor OS=Rattus norvegicus OX=10116 GN=Neurod4 PE=4 SV=1 CANONICAL=D4A7M5-1" }, "locus": { "chromosome": "7", "start_pos": 7093277, "end_pos": 7092288, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000011167.7", "url": "https://www.ensembl.org/id/ENSRNOT00000011167.7" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000011167.3", "url": "https://www.ensembl.org/id/ENSRNOP00000011167.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "motor neuron migration", "id": "GO:0097475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097475", "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "pmid": "" }, { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "pmid": "" }, { "name": "positive regulation of cell differentiation", "id": "GO:0045597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045597", "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "pmid": "" }, { "name": "neuroblast proliferation", "id": "GO:0007405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007405", "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "pmid": "" }, { "name": "axon development", "id": "GO:0061564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061564", "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "pmid": "" }, { "name": "camera-type eye development", "id": "GO:0043010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043010", "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "pmid": "" }, { "name": "oligodendrocyte differentiation", "id": "GO:0048709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048709", "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "pmid": "" }, { "name": "cell fate commitment", "id": "GO:0045165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045165", "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "pmid": "" }, { "name": "amacrine cell differentiation", "id": "GO:0035881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035881", "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "pmid": "" }, { "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "D4A7M5", "url": "https://www.uniprot.org/uniprot/D4A7M5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }