{
    "uniprot_canonical_ac": "D3ZXB7-1",
    "uniprot_ac": "D3ZXB7",
    "uniprot_id": "D3ZXB7_RAT",
    "mass": {
        "chemical_mass": 57637.0,
        "monoisotopic_mass": 57637.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Krt71",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/D3ZXB7",
            "id": "D3ZXB7"
        }
    ],
    "protein_names": [
        {
            "name": "Keratin 71",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "D3ZXB7"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0110710",
            "recommended_name": {
                "id": "DOID:0110710",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0110710",
                "name": "hypotrichosis 13",
                "description": "A hypotrichosis that has_material_basis_in a autosomal dominant mutation of the KRT71 gene on chromosome 12q13.13."
            },
            "synonyms": [
                {
                    "id": "DOID:0110710",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110710",
                    "name": "Hypt13",
                    "description": ""
                },
                {
                    "id": "DOID:0110710",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110710",
                    "name": "hypotrichosis with woolly hair",
                    "description": ""
                },
                {
                    "id": "MONDO:0014390",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014390",
                    "name": "hypotrichosis 13",
                    "description": "Any hypotrichosis in which the cause of the disease is a mutation in the KRT71 gene."
                },
                {
                    "id": "MONDO:0014390",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014390",
                    "name": "KRT71 hypotrichosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0014390",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014390",
                    "name": "hypotrichosis 13",
                    "description": ""
                },
                {
                    "id": "MONDO:0014390",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014390",
                    "name": "hypotrichosis caused by mutation in KRT71",
                    "description": ""
                },
                {
                    "id": "MONDO:0014390",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014390",
                    "name": "hypotrichosis type 13",
                    "description": ""
                },
                {
                    "id": "MONDO:0014390",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014390",
                    "name": "hypotrichosis with woolly hair",
                    "description": ""
                },
                {
                    "id": "MONDO:0014390",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014390",
                    "name": "hypotrichosis with wooly hair",
                    "description": ""
                },
                {
                    "id": "MONDO:0014390",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014390",
                    "name": "hypt13",
                    "description": ""
                },
                {
                    "id": "MONDO:0014390",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014390",
                    "name": "HYPT13",
                    "description": ""
                },
                {
                    "id": "MIM:615896",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/615896",
                    "name": "Hypotrichosis 13",
                    "description": "Hypotrichosis 13"
                }
            ],
            "evidence": [
                {
                    "id": "0110710",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110710"
                }
            ]
        },
        {
            "disease_id": "DOID:987",
            "recommended_name": {
                "id": "DOID:987",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:987",
                "name": "alopecia",
                "description": "A hypotrichosis that is characterized by a loss of hair from the head or body."
            },
            "synonyms": [
                {
                    "id": "MONDO:0008757",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008757",
                    "name": "alopecia universalis congenita",
                    "description": "The most severe form of alopecia areata, an inflammatory disease of the hair follicle, which is characterized by a complete loss of hair of the scalp and all the hair-bearing areas of the body."
                },
                {
                    "id": "MONDO:0008757",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008757",
                    "name": "alopecia universalis congenita",
                    "description": ""
                },
                {
                    "id": "MONDO:0008757",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008757",
                    "name": "atrichia, generalised",
                    "description": ""
                },
                {
                    "id": "MONDO:0008757",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008757",
                    "name": "atrichia, generalized",
                    "description": ""
                },
                {
                    "id": "MONDO:0008757",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008757",
                    "name": "ALUNC",
                    "description": ""
                },
                {
                    "id": "MONDO:0008757",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008757",
                    "name": "AU",
                    "description": ""
                },
                {
                    "id": "MONDO:0008757",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008757",
                    "name": "alopecia areata universalis",
                    "description": ""
                },
                {
                    "id": "MONDO:0008757",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008757",
                    "name": "alopecia universalis",
                    "description": ""
                },
                {
                    "id": "MIM:203655",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/203655",
                    "name": "Alopecia universalis congenita",
                    "description": "Alopecia universalis congenita"
                }
            ],
            "evidence": [
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                    "id": "987",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:987"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "D3ZXB7",
                    "url": "https://www.uniprot.org/uniprot/D3ZXB7"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Krt71",
            "url": "https://www.uniprot.org/uniprot/D3ZXB7",
            "locus": {
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                "start_pos": 132873540,
                "end_pos": 132882325,
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                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000049495",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000049495"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000049495",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000049495",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "IPR003054",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003054",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018039",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR032444",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR032444",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR039008",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:683613",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:683613",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "DIKFFRC",
            "url": "https://omabrowser.org/oma/group/DIKFFRC/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4640531at2759",
            "url": "http://www.orthodb.org/?query=4640531at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR45616",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR45616:SF16",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616:SF16",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00038",
            "url": "http://pfam.xfam.org/family/PF00038",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF16208",
            "url": "http://pfam.xfam.org/family/PF16208",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-6805567",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6805567",
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            "categories": [
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            ]
        },
        {
            "id": "R-RNO-6809371",
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            "database": "Reactome",
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            ]
        },
        {
            "id": "1584538",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1584538",
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            ]
        },
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        },
        {
            "id": "D3ZXB7-1",
            "url": "https://www.uniprot.org/uniprot/D3ZXB7-1",
            "database": "UniProtKB",
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                "Protein"
            ]
        }
    ],
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        "sequence": "NSMSRQFTCKSGAGNRGFSGCSAVLSGGSSSSYRAGGKGLSGGFGSRSLYSLGGPRSITLNMASGSGKNGGFGFGRNRASGFAGSIFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNMRKQLETLSGDRVRLDSELRNVRDVVEDYKKKYEEEINRRTAAENEFVLLKKDVDAAYANKVELQAKVDTMDQDIKFFKCLFEAEMAQIQSHISDMSVILSMDNNRNLDLDSIIDEVRAQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEITELTRFIQRLRSEIENAKKQASNLETAIADAEQRGDSALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEYSSPVSISIISSTSGSGGYGFRPSTVSGGYVANSTSCISGVCSVRGGENRSRGSASDYKDSLTKGSSLSTPSKKGGR",
        "length": 526,
        "header": "tr|D3ZXB7-1|D3ZXB7_RAT Isoform 1 of Keratin 71  OS=Rattus norvegicus OX=10116 GN=Krt71 PE=3 SV=3 CANONICAL=D3ZXB7-1"
    },
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        {
            "isoform_ac": "D3ZXB7-1",
            "url": "",
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                "sequence": "NSMSRQFTCKSGAGNRGFSGCSAVLSGGSSSSYRAGGKGLSGGFGSRSLYSLGGPRSITLNMASGSGKNGGFGFGRNRASGFAGSIFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNMRKQLETLSGDRVRLDSELRNVRDVVEDYKKKYEEEINRRTAAENEFVLLKKDVDAAYANKVELQAKVDTMDQDIKFFKCLFEAEMAQIQSHISDMSVILSMDNNRNLDLDSIIDEVRAQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEITELTRFIQRLRSEIENAKKQASNLETAIADAEQRGDSALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEYSSPVSISIISSTSGSGGYGFRPSTVSGGYVANSTSCISGVCSVRGGENRSRGSASDYKDSLTKGSSLSTPSKKGGR",
                "length": 526,
                "header": "tr|D3ZXB7-1|D3ZXB7_RAT Isoform 1 of Keratin 71  OS=Rattus norvegicus OX=10116 GN=Krt71 PE=3 SV=3 CANONICAL=D3ZXB7-1"
            },
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                "chromosome": "7",
                "start_pos": 132882270,
                "end_pos": 132874061,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000068533.4",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000068533.4"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000059953.3",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000059953.3"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:683613",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:683613",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-6805567",
            "name": "Keratinization",
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            "resource": "Reactome",
            "description": "Keratinization"
        },
        {
            "id": "R-RNO-6809371",
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            "resource": "Reactome",
            "description": "Formation of the cornified envelope"
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    ],
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            {
                "name": "Biological Process",
                "total": 3,
                "go_terms": [
                    {
                        "name": "keratinization",
                        "id": "GO:0031424",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031424",
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                                "url": "https://www.uniprot.org/uniprot/D3ZXB7"
                            }
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                    },
                    {
                        "name": "intermediate filament organization",
                        "id": "GO:0045109",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109",
                        "evidence": [
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                                "id": "D3ZXB7",
                                "url": "https://www.uniprot.org/uniprot/D3ZXB7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "hair follicle morphogenesis",
                        "id": "GO:0031069",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031069",
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                                "database": "UniProtKB",
                                "id": "D3ZXB7",
                                "url": "https://www.uniprot.org/uniprot/D3ZXB7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "keratin filament",
                        "id": "GO:0045095",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095",
                        "evidence": [
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                                "id": "D3ZXB7",
                                "url": "https://www.uniprot.org/uniprot/D3ZXB7"
                            }
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                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "structural constituent of skin epidermis",
                        "id": "GO:0030280",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030280",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D3ZXB7",
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                            }
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                        "pmid": ""
                    }
                ]
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        ]
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    "pro_annotation": [],
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        {
            "start_pos": 111,
            "end_pos": 113,
            "annotation": "n_glycosylation_sequon"
        },
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            "annotation": "n_glycosylation_sequon"
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        {
            "start_pos": 498,
            "end_pos": 500,
            "annotation": "n_glycosylation_sequon"
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    ],
    "ptm_annotation": [],
    "interactions": [],
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    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [],
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        {
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