{
    "uniprot_canonical_ac": "D3ZVT2-1",
    "uniprot_ac": "D3ZVT2",
    "uniprot_id": "D3ZVT2_RAT",
    "mass": {
        "chemical_mass": 217238.0,
        "monoisotopic_mass": 217238.0
    },
    "refseq": {
        "ac": "NP_001178698",
        "name": "thyroid adenoma-associated protein",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178698"
    },
    "gene_names": [
        {
            "name": "Thada",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/D3ZVT2",
            "id": "D3ZVT2"
        },
        {
            "name": "RGD1560519",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178698",
            "id": "NP_001178698"
        },
        {
            "name": "Thada",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178698",
            "id": "NP_001178698"
        }
    ],
    "protein_names": [
        {
            "name": "THADA, armadillo repeat containing",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "D3ZVT2"
        },
        {
            "name": "thyroid adenoma associated",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178698",
            "id": "NP_001178698"
        },
        {
            "name": "thyroid adenoma-associated protein",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178698",
            "id": "NP_001178698"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0050776",
            "recommended_name": {
                "id": "DOID:0050776",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050776",
                "name": "non-syndromic X-linked intellectual disability",
                "description": "A non-syndromic intellectual disability characterized by a X-linked inheritance pattern."
            },
            "synonyms": [
                {
                    "id": "DOID:0050776",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050776",
                    "name": "non-specific X-linked mental retardation",
                    "description": ""
                },
                {
                    "id": "MONDO:0010413",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010413",
                    "name": "intellectual disability, X-linked 95",
                    "description": ""
                },
                {
                    "id": "MONDO:0010413",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010413",
                    "name": "MRX95",
                    "description": ""
                },
                {
                    "id": "MONDO:0010413",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010413",
                    "name": "intellectual disability, X-linked 95",
                    "description": ""
                },
                {
                    "id": "MONDO:0010413",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010413",
                    "name": "mental retardation, X-linked 95, X-linked dominant",
                    "description": ""
                },
                {
                    "id": "MONDO:0010413",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010413",
                    "name": "mental retardation, X-linked 95",
                    "description": ""
                },
                {
                    "id": "MONDO:0010656",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010656",
                    "name": "intellectual disability, X-linked 1",
                    "description": "An X-linked dominant condition caused by mutation(s) in the IQSEC2 gene, encoding IQ motif and SEC7 domain-containing protein 2. It is characterized by substantially impaired intellectual functioning and behavioral abnormalities."
                },
                {
                    "id": "MONDO:0010656",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010656",
                    "name": "MRX",
                    "description": ""
                },
                {
                    "id": "MONDO:0010656",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010656",
                    "name": "MRX1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010656",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010656",
                    "name": "MRX78",
                    "description": ""
                },
                {
                    "id": "MONDO:0010656",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010656",
                    "name": "intellectual developmental disorder, X-linked 1, X-linked dominant",
                    "description": ""
                },
                {
                    "id": "MONDO:0010656",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010656",
                    "name": "intellectual disability, X-linked 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010656",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010656",
                    "name": "mental retardation, X-linked 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010656",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010656",
                    "name": "mental retardation, X-linked 18",
                    "description": ""
                },
                {
                    "id": "MONDO:0010656",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010656",
                    "name": "mental retardation, X-linked 78",
                    "description": ""
                },
                {
                    "id": "MONDO:0010656",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010656",
                    "name": "mental retardation, X-linked type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010656",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010656",
                    "name": "IQSEC2",
                    "description": ""
                },
                {
                    "id": "MONDO:0010656",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010656",
                    "name": "IQSEC2-related epilepsy",
                    "description": ""
                },
                {
                    "id": "MONDO:0010656",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010656",
                    "name": "IQSEC2-related intellectual disability",
                    "description": ""
                },
                {
                    "id": "MONDO:0010656",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010656",
                    "name": "X-linked intellectual disability 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010656",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010656",
                    "name": "X-linked intellectual disability 1/78",
                    "description": ""
                },
                {
                    "id": "MONDO:0010656",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010656",
                    "name": "X-linked intellectual disability 78",
                    "description": ""
                },
                {
                    "id": "MIM:309530",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/309530",
                    "name": "Intellectual developmental disorder, X-linked 1",
                    "description": "Intellectual developmental disorder, X-linked 1"
                }
            ],
            "evidence": [
                {
                    "id": "0050776",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050776"
                }
            ]
        },
        {
            "disease_id": "DOID:9970",
            "recommended_name": {
                "id": "DOID:9970",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:9970",
                "name": "obesity",
                "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness."
            },
            "synonyms": [
                {
                    "id": "MONDO:0019182",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0019182",
                    "name": "inherited obesity",
                    "description": ""
                },
                {
                    "id": "MONDO:0019182",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0019182",
                    "name": "genetic obesity",
                    "description": ""
                },
                {
                    "id": "MONDO:0019182",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0019182",
                    "name": "genetic obesity (disease)",
                    "description": ""
                },
                {
                    "id": "MONDO:0019182",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0019182",
                    "name": "leanness, inherited, autosomal recessive",
                    "description": ""
                },
                {
                    "id": "MONDO:0019182",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0019182",
                    "name": "monogenic obesity",
                    "description": ""
                },
                {
                    "id": "MONDO:0019182",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0019182",
                    "name": "obesity, association with, Autosomal recessive",
                    "description": ""
                },
                {
                    "id": "MONDO:0019182",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0019182",
                    "name": "obesity, early-onset, susceptibility to, Autosomal recessive",
                    "description": ""
                },
                {
                    "id": "MONDO:0019182",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0019182",
                    "name": "obesity, late-onset, Autosomal recessive",
                    "description": ""
                },
                {
                    "id": "MONDO:0019182",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0019182",
                    "name": "obesity, mild, early-onset, Autosomal recessive",
                    "description": ""
                },
                {
                    "id": "MONDO:0019182",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0019182",
                    "name": "obesity, severe, Autosomal recessive",
                    "description": ""
                },
                {
                    "id": "MONDO:0019182",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0019182",
                    "name": "obesity, severe, and type II diabetes, Autosomal recessive",
                    "description": ""
                },
                {
                    "id": "MONDO:0019182",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0019182",
                    "name": "obesity, susceptibility to, Autosomal recessive",
                    "description": ""
                },
                {
                    "id": "MIM:601665",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/601665",
                    "name": "Obesity",
                    "description": "Obesity"
                }
            ],
            "evidence": [
                {
                    "id": "9970",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:9970"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "D3ZVT2",
                    "url": "https://www.uniprot.org/uniprot/D3ZVT2"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Thada",
            "url": "https://www.uniprot.org/uniprot/D3ZVT2",
            "locus": {
                "chromosome": "6",
                "start_pos": 10487159,
                "end_pos": 10183982,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000025899",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000025899"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000025899",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000025899",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "313865",
            "url": "https://www.ncbi.nlm.nih.gov/gene/313865",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR011989",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR016024",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR019442",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019442",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:313865",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:313865",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "CTSIPEW",
            "url": "https://omabrowser.org/oma/group/CTSIPEW/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "227148at2759",
            "url": "http://www.orthodb.org/?query=227148at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR14387",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14387",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR14387:SF7",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14387:SF7",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF10350",
            "url": "http://pfam.xfam.org/family/PF10350",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001178698",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178698",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1560519",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1560519",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A8I5ZTM5",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZTM5",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5ZTM5-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZTM5-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3ZVT2",
            "url": "https://www.uniprot.org/uniprot/D3ZVT2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3ZVT2-1",
            "url": "https://www.uniprot.org/uniprot/D3ZVT2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MGVKKKREMQFAALTVCHQDLETLRSFADVEGKNLASLLLHCVQLTDGVSQIHSVKQIVPLLEKVDKNGVCDPIIQRCLDILASIYFSLTLKNPLKKVLASSLNGLPECFLNEAAHSFTFHLQEELDTADLHSYRKVMDNISSCMENFNLGRASVVNLLQNVLHFLQKSLIEVQEENRKFAGNHIVQTQLMNDLLVGVRVAMTLVQKVQGPQSNLWNDSSSPIWQSMCGLLSIFTRFLNDDDLLQTIQSTSGLAVILFIKTMFRPSEKLPGLISSLLLQSADCTSIPDWLMSSCRSLCCADVPASALLFLCQGTLAMLDWQDGSMGPSREALLLDTVHVLFTLSSQIKESTLEMFLSRILASWTNSAIQILESSSPSLKDHLNGDSSIPRRLLEYVYTHWEHPLDALRHQTKIIFRNLLQMHRLTIEGADLVTDPFFLELTKSLLQLEWHIKGKYACLGYLVESLGIEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFKNHKSHLKSQTVTNTWMDKWHETWVFPVLSVLCGGNLDQRSYVIDYYLPRLLNYSPESLHYMVQILQTPIDTETGSCNHRGALGALMACLRTARAHGHLQSATHAWENLVCSARVKQGLIHQHCQVRIDTLGLLCESSRSTEVVSREEMQWVQFFLTYNLNSQSPGVRQQICSLLTKLFCRIQESSQVLYKLEQRNSTPDSEKRSTREQPSVSLQQYKNFMSSVCNILFEALFPGSSYSTRFSALTILGSIAEVFPASKGNIQTVYQLSHDIDAGRFQILMECFTSTFEEVKTLAFDLLMNLSSVTAGQLQGSEKLQDLFQAALELSTSTKPYDCVTASYLLNLLIWQDALPASLSASSAQQPTCGAGEKSAVVERNTLVVIKCLMENLEDEISQAENSLLQAASSFPMYGRVHCITRAFQKLPLHDLRLVSEWKPVLGKLLLLSYRLSTVVSPVIQSSSPEGLIPMDTDSESASRLQVILNEIQPRDTNDYFSQAKILKECDSFDLEDLSTSVSNIDSSAEIKGKEEKACDVTAQMVLTCCWRSMKEVALLLGTLCQLLPLQPVPESAAGLLTVQQVKEIGEYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSNVSLQKLPEQWLWSVLEEIKSSDPSSKLCATRRSAGIPFYIQALLASEPKKGRMDLLRVTMRELISLALSADDSKGRVPQVHALNILRALFRDTRLGENIIPYVAGGAKAAILGFTSPVWAVRNSSTLLFSSLITRVFGVKRGKDELSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDLGDPDGHPGMFLLLLVLERLYPSPMDGTASTLSLAPFVPFIIRCGRSPFYRSREMAARALVPFITIDQIPSTLHALLDSLPSSTDQCFRQNHIHGTLLQVFHLLQAYITDSKHRINADFLQELSDITVCTKAKLWLAMRQNPCLVTRAVYIDILFLLTHCLDRPEEGKHTALESLDFWEDVRRIILGSELITGFPWTFKVPGLPQYLQSLTKLAIPEVWASLAEAEGQATAVPLSFSQLLKSSFPEVRLLALDALLERAASSEQGQKGPPPLLYSMGEEFLLLAMKEDHPGCFCRVLKILYHLNPSEWLPQTECSVHLSPKEFLVWTMDIASNDRSEIQGVSLRLASKIIAYLVQSCEKNKDSVALELRRWVQLIVWSCGDHLPTASRLAVAEVLSGTAPLFLTSPQPILDLQDTLSLWRCVLTLLQSEEQPVREAATETVTTAMSQGNTCQSTEFAFCQVDASIALTLAFAVLCDLLQQWDQLGPGLPILLGWLLEEGGDLKDLMQSPHQGEEEHIFEKSEVNFWAETLTFVKYLCNQVFHLLCQSGCQSSHSQLSHLQRTASEQHRLISQLFRELPLSAEFLKTVEYTRLRIQEERTLAVLRLLACLEGKEVLRAEDCPREWRQEMAPRTEAAC",
        "length": 1937,
        "header": "tr|D3ZVT2-1|D3ZVT2_RAT Isoform 1 of THADA, armadillo repeat containing  OS=Rattus norvegicus OX=10116 GN=Thada PE=1 SV=1 CANONICAL=D3ZVT2-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A8I5ZTM5-1",
            "url": "",
            "sequence": {
                "sequence": "MGVKKKREMQFAALTVCHQDLETLRSFADVEGKNLASLLLHCVQLTDGVSQIHSVKQIVPLLEKVDKNGVCDPIIQRCLDILASIYFSLTLKNPLKKVLASSLNGLPECFLNEAAHSFTFHLQEELDTADLHSYRKVMDNISSCMENFNLGKPALPQLLHFLQKSLIEVQEENRKFAGNHIVQTQLMNDLLVGVRVAMTLVQKVQGPQSNLWNDSSSPIWQSMCGLLSIFTRFLNDDDLLQTIQSTSGLAVILFIKTMFRPSEKLPGLISSLLLQSADCTSIPDWLMSSCRSLCCADVPASALLFLCQGTLAMLDWQDGSMGPSREALLLDTVHVLFTLSSQIKESTLEMFLSRILASWTNSAIQILESSSPSLKDHLNGDSSIPRRLLEYVYTHWEHPLDALRHQTKIIFRNLLQMHRLTIEGADLVTDPFFLELTKSLLQLEWHIKGKYACLGYLVESLGIEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFKNHKSHLKSQTVTNTWMDKWHETWVFPVLSVLCGGNLDQRSYVIDYYLPRLLNYSPESLHYMVQILQTPIDTETGSCNHRGALGALMACLRTARAHGHLQSATHAWENLVCSARVKQGLIHQHCQVRIDTLGLLCESSRSTEVVSREEMQWVQFFLTYNLNSQSPGVRQQICSLLTKLFCRIQESSQVLYKLEQRNSTPDSEKRSTREQPSVSLQQYKNFMSSVCNILFEALFPGSSYSTRFSALTILGSIAEVFPASKGNIQTVYQLSHDIDAGRFQILMECFTSTFEEVKTLAFDLLMNLSSVTAGQLQGSEKLQDLFQAALELSTSTKPYDCVTASYLLNLLIWQDALPASLSASSAQQPTCGAGEKSAVVERNTLVVIKCLMENLEDEISQAENSLLQAASSFPMYGRVHCITRAFQKLPLHDLRLVSEWKPVLGKLLLLSYRLSTVVSPVIQSSSPEGLIPMDTDSESASRLQVILNEIQPRDTNDYFSQAKILKECDSFDLEDLSTSVSNIDSSAEIKGKEEKACDVTAQMVLTCCWRSMKEVALLLGTLCQLLPLQPVPESAAGLLTVQQVKEIGEYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSNVSLQKLPEQWLWSVLEEIKSSDPSSKLCATRRSAGIPFYIQALLASEPKKGRMDLLRVTMRELISLALSADDSKGRVPQVHALNILRALFRDTRLGENIIPYVAGGAKAAILGFTSPVWAVRNSSTLLFSSLITRVFGVKRGKDELSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDLGDPDGHPGMFLLLLVLERLYPSPMDGTASTLSLAPFVPFIIRCGRSPFYRSREMAARALVPFITIDQIPSTLHALLDSLPSSTDQCFRQNHIHGTLLQVFHLLQAYITDSKHRINADFLQELSDITVCTKAKLWLAMRQNPCLVTRAVYIDILFLLTHCLDRPEEGKHTALESLDFWEDVRRIILGSELITGFPWTFKVPGLPQYLQSLTKLAIPEVWASLAEAEGQATAVPLSFSQLLKSSFPEVRLLALDALLERAASSEQGQKGPPPLLYSMGEEFLLLAMKEDHPGCFCRVLKILYHLNPSEWLPQTECSVHLSPKEFLVWTMDIASNDRSEIQGVSLRLASKIIAYLVQSCEKNKDSVALELRRWVQLIVWSCGDHLPTASRLAVAEVLSGTAPLFLTSPQPILDLQDTLSLWRCVLTLLQSEEQPVREAATETVTTAMSQGNTCQSTEFAFCQVDASIALTLAFAVLCDLLQQWDQLGPGLPILLGWLLEEGGDLKDLMQSPHQGEEEHIFEKSEVNFWAETLTFVKYLCNQVFHLLCQSGCQSSHSQLSHLQRTASEQHRLISQLFRELPLSAEFLKTVEYTRLRIQEERTLAVLRLLACLEGKEVLRAEDCPREWRQEMAPRTEAAC",
                "length": 1933,
                "header": "tr|A0A8I5ZTM5-1|D3ZVT2_RAT Computationally mapped isoform of THADA, armadillo repeat containing  OS=Rattus norvegicus OX=10116 GN=Thada PE=1 SV=1 CANONICAL=D3ZVT2-1"
            },
            "locus": {
                "chromosome": "6",
                "start_pos": 10486100,
                "end_pos": 10185999,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000099338.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000099338.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000081786.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000081786.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D3ZVT2-1",
            "url": "",
            "sequence": {
                "sequence": "MGVKKKREMQFAALTVCHQDLETLRSFADVEGKNLASLLLHCVQLTDGVSQIHSVKQIVPLLEKVDKNGVCDPIIQRCLDILASIYFSLTLKNPLKKVLASSLNGLPECFLNEAAHSFTFHLQEELDTADLHSYRKVMDNISSCMENFNLGRASVVNLLQNVLHFLQKSLIEVQEENRKFAGNHIVQTQLMNDLLVGVRVAMTLVQKVQGPQSNLWNDSSSPIWQSMCGLLSIFTRFLNDDDLLQTIQSTSGLAVILFIKTMFRPSEKLPGLISSLLLQSADCTSIPDWLMSSCRSLCCADVPASALLFLCQGTLAMLDWQDGSMGPSREALLLDTVHVLFTLSSQIKESTLEMFLSRILASWTNSAIQILESSSPSLKDHLNGDSSIPRRLLEYVYTHWEHPLDALRHQTKIIFRNLLQMHRLTIEGADLVTDPFFLELTKSLLQLEWHIKGKYACLGYLVESLGIEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFKNHKSHLKSQTVTNTWMDKWHETWVFPVLSVLCGGNLDQRSYVIDYYLPRLLNYSPESLHYMVQILQTPIDTETGSCNHRGALGALMACLRTARAHGHLQSATHAWENLVCSARVKQGLIHQHCQVRIDTLGLLCESSRSTEVVSREEMQWVQFFLTYNLNSQSPGVRQQICSLLTKLFCRIQESSQVLYKLEQRNSTPDSEKRSTREQPSVSLQQYKNFMSSVCNILFEALFPGSSYSTRFSALTILGSIAEVFPASKGNIQTVYQLSHDIDAGRFQILMECFTSTFEEVKTLAFDLLMNLSSVTAGQLQGSEKLQDLFQAALELSTSTKPYDCVTASYLLNLLIWQDALPASLSASSAQQPTCGAGEKSAVVERNTLVVIKCLMENLEDEISQAENSLLQAASSFPMYGRVHCITRAFQKLPLHDLRLVSEWKPVLGKLLLLSYRLSTVVSPVIQSSSPEGLIPMDTDSESASRLQVILNEIQPRDTNDYFSQAKILKECDSFDLEDLSTSVSNIDSSAEIKGKEEKACDVTAQMVLTCCWRSMKEVALLLGTLCQLLPLQPVPESAAGLLTVQQVKEIGEYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSNVSLQKLPEQWLWSVLEEIKSSDPSSKLCATRRSAGIPFYIQALLASEPKKGRMDLLRVTMRELISLALSADDSKGRVPQVHALNILRALFRDTRLGENIIPYVAGGAKAAILGFTSPVWAVRNSSTLLFSSLITRVFGVKRGKDELSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDLGDPDGHPGMFLLLLVLERLYPSPMDGTASTLSLAPFVPFIIRCGRSPFYRSREMAARALVPFITIDQIPSTLHALLDSLPSSTDQCFRQNHIHGTLLQVFHLLQAYITDSKHRINADFLQELSDITVCTKAKLWLAMRQNPCLVTRAVYIDILFLLTHCLDRPEEGKHTALESLDFWEDVRRIILGSELITGFPWTFKVPGLPQYLQSLTKLAIPEVWASLAEAEGQATAVPLSFSQLLKSSFPEVRLLALDALLERAASSEQGQKGPPPLLYSMGEEFLLLAMKEDHPGCFCRVLKILYHLNPSEWLPQTECSVHLSPKEFLVWTMDIASNDRSEIQGVSLRLASKIIAYLVQSCEKNKDSVALELRRWVQLIVWSCGDHLPTASRLAVAEVLSGTAPLFLTSPQPILDLQDTLSLWRCVLTLLQSEEQPVREAATETVTTAMSQGNTCQSTEFAFCQVDASIALTLAFAVLCDLLQQWDQLGPGLPILLGWLLEEGGDLKDLMQSPHQGEEEHIFEKSEVNFWAETLTFVKYLCNQVFHLLCQSGCQSSHSQLSHLQRTASEQHRLISQLFRELPLSAEFLKTVEYTRLRIQEERTLAVLRLLACLEGKEVLRAEDCPREWRQEMAPRTEAAC",
                "length": 1937,
                "header": "tr|D3ZVT2-1|D3ZVT2_RAT Isoform 1 of THADA, armadillo repeat containing  OS=Rattus norvegicus OX=10116 GN=Thada PE=1 SV=1 CANONICAL=D3ZVT2-1"
            },
            "locus": {
                "chromosome": "6",
                "start_pos": 10486100,
                "end_pos": 10185999,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000038246.7",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000038246.7"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000032728.4",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000032728.4"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:313865",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:313865",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "A8C756-1",
            "protein_name": "tRNA (32-2'-O)-methyltransferase regulator THADA",
            "gene_name": "Thada",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MGVKKKREMQVAALTVCHQDMETLRSFADMEGKNLASLLLHCVQLTDGVSQIHSIKQIVPLLEKVDKNGVCDPAIQSCLDILAGIYFSLTLKNPLKKVLASSLNGLPEVFLTQATHSFTFHLQEELDTADLYSYRKVMDNISSCMENFNLGRASVVNLLKDVLHFLQKSLIEILEENRKFAGNRIVQTQLMSDLLVGVRVAMTLVQKVQGPQGSLWNDSSSPIWQSMCGLLSIFTKFLNDDDLLQTVESTSGLAVILFIKTMFRPSEKLPGLISSLLLRSAECTSIPEWLMNSCRSLCCTDVPASTLLFLCQGTLAMLDWQDGSMGPSGEALLLDIVHVLFTLSSQIKESTLDMFLSRILASWTSSAIQILESGSSGLKGHLNGDSCVPRRLLEYVYTHWEHPLDALRHQTKVMFRNLLQMHRLTMEGADLATDPFCLELTKSLLQLEWHIKGKYACLGCLVETLGIEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFKNHKSHLKSQTVTNTWMDKWHETWVFPVLSVLCGGNLDQRSYVIDYYLPRILNYSPESLHYMVHILQASTDTGTGSCNHRGALGALMACLRTARAHGHLQSATQAWENLVCSARVKQGLIHQHCQVRIDTLGLLCESNRSTEVVSTEEMQWVQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQRKSTPDSENGSIREQPSVTLQQYKNFMSSVCNILFEALFPGSSYSTRFSALTILGSVAEVFPDPEGNIQTVYQLSHDIDAGRYQILMECFTSTFEEVKTLAFDLLMKLSSVTAGQFQDSEKLQDLFQAALELSTSTKPYDCVTASYLLNLLIRQDALPAVLSASSPQQLTRGAGETSAVLERNTLVVIKCLMENLEDEISQAENSLLQAASSFPMYGRVHCITRAFQRLPLNDLRLASEWRPLLGRLLLLSYRLSTVVAPVIQSSSPEGLIPVDTDSASASRLQLILNEIQPRDTNDYFNHTKILKECDSFDLEDLSTSVSNIDSSAEVKGKEEKACDVTAQMVLACCWRSMKEVALLLGTLCQLLPVQPGPESSNVFLTVQQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSNVSLQKLPEQWLRSVLEEIKGSDPSSKLCATRRSAGIPFYIQALLASEPKKSRMDLLKITMRELISLALSADDSKGRVPQVHALNILRALFRDTRLGENIIPYVAGGAKAAILGFTSPVWAVRNSSTLLFSSLITRVFGVKRGKDEVSKTNRMTGREFFSRFPELYPFLLKQLETVASTVDSELGEPDRHPGMFLLLLVLERLYPSPMDGTSSALSLAPFVPFIIRCGRSPIYRSREMAARALVPFIMIDQIPSTLCALLNSLPNSTDQCFRQNHIHGTLLQVFHLLQAYITDCRHRTNADFLQELSDVTACTKAKLWLAMRQNPCLVTRAVYIDILFLLTNCLDRPEEGKQTALESLGFWEDVRRIILESELIKGFPWTFKVPGLPQYLQSLTKLAIPEVWASLAEAKGQATAVPLSFSRLLKSSFPEVRLLALDTLLERARSSEQEQKEPLPLLCSMGEELLLLAMKEDHPGCFCRVLKILYHLNPSEWLPQTECYAHLSPKEFLMWSMDIASNDRSEIQGVALKLASKIIAYRVQSCEKNKDSLAPELRQWVQLVVWSCGDHLPTASRLAVAEVLTSTAPLFLTSPQPILELQGTLSLWRCVLTLLQSEEQTVREAATEIVTTAMSQGNTCQSTEFAFCQVDASIALTLALAVLCDLLQQWDQLEPGLPILLGWLLEEGDDLEGHVQSPHQGEEEHIFEKSEVNFWAETLTFVKSLCRQLFHLLCQSGWQSPHSQKLCHLQRIASEQSHLISQLFRELPLSAEFLKTVEYTRLRIQEERTLAVLRLLACLEGKEGLRAEDCPREWRQVMAPRTEAAC",
                "length": 1938
            },
            "evidence": [
                {
                    "id": "45236773",
                    "url": "http://www.informatics.jax.org/homology/45236773",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q6YHU6-1",
            "protein_name": "tRNA (32-2'-O)-methyltransferase regulator THADA",
            "gene_name": "THADA",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MGVKKKKEMQVAALTICHQDLETLKSFADVEGKNLASLLLHCVQLTDGVSQIHYIKQIVPLLEKADKNGMCDPTIQSCLDILAGIYLSLSLKNPLKKVLASSLNSLPDFFLPEAMHRFTSRLQEELNTTDLYSYRKVTDNISSCMENFNLGRASVNNLLKNVLHFLQKSLIEILEENRKCAGNHIIQTQLMNDLLVGIRVSMMLVQKVQDFQGNLWKTSDSPIWQNMCGLLSIFTKVLSDDDLLQTVQSTSGLAIILFIKTMFHPSEKIPHLISSVLLRSVDCTSVPEWFMSSCRSLCCGDISQSAVLFLCQGTLAMLDWQNGSMGRSGEALLLDTAHVLFTLSSQIKEPTLEMFLSRILASWTNSAIQVLESSSPSLTDSLNGNSSIVGRLLEYVYTHWEHPLDALRHQTKIMFKNLLQMHRLTVEGADFVPDPFFVELTESLLRLEWHIKGKYTCLGCLVECIGVEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFRNHKSHLKSQTAESSWIDQWHETWVSPLLFILCEGNLDQKSYVIDYYLPKLLSYSPESLQYMVKILQTSIDAKTGQEQSFPSLGSCNSRGALGALMACLRIARAHGHLQSATDTWENLVSDARIKQGLIHQHCQVRIDTLGLLCESNRSTEIVSMEEMQWIQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQSKSKREPENELTKQHPSVSLQQYKNFMSSICNSLFEALFPGSSYSTRFSALTILGSIAEVFHVPEGRIYTVYQLSHDIDVGRFQTLMECFTSTFEDVKILAFDLLMKLSKTAVHFQDSGKLQGLFQAALELSTSTKPYDCVTASYLLNFLIWQDALPSSLSAYLTQQVACDNGDRPAAVVERNTLMVIKCLMENLEEEVSQAENSLLQAAAAFPMYGRVHCITGALQKLSLNSLQLVSEWRPVVEKLLLMSYRLSTVVSPVIQSSSPEGLIPMDTDSESASRLQMILNEIQPRDTNDYFNQAKILKEHDSFDMKDLNASVVNIDTSTEIKGKEVKTCDVTAQMVLVCCWRSMKEVALLLGMLCQLLPMQPVPESSDGLLTVEQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEVLNRCPNVSLQKLPEQWLWSVLEEIKCSDPSSKLCATRRSAGIPFYIQALLASEPKKGRMDLLKITMKELISLAGPTDDIQSTVPQVHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSALITRIFGVKRAKDEHSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDMGEPNRHPSMFLLLLVLERLYASPMDGTSSALSMGPFVPFIMRCGHSPVYHSREMAARALVPFVMIDHIPNTIRTLLSTLPSCTDQCFRQNHIHGTLLQVFHLLQAYSDSKHGTNSDFQHELTDITVCTKAKLWLAKRQNPCLVTRAVYIDILFLLTCCLNRSAKDNQPVLESLGFWEEVRGIISGSELITGFPWAFKVPGLPQYLQSLTRLAIAAVWAAAAKSGERETNVPISFSQLLESAFPEVRSLTLEALLEKFLAAASGLGEKGVPPLLCNMGEKFLLLAMKENHPECFCKILKILHCMDPGEWLPQTEHCVHLTPKEFLIWTMDIASNERSEIQSVALRLASKVISHHMQTCVENRELIAAELKQWVQLVILSCEDHLPTESRLAVVEVLTSTTPLFLTNPHPILELQDTLALWKCVLTLLQSEEQAVRDAATETVTTAMSQENTCQSTEFAFCQVDASIALALALAVLCDLLQQWDQLAPGLPILLGWLLGESDDLVACVESMHQVEEDYLFEKAEVNFWAETLIFVKYLCKHLFCLLSKSGWRPPSPEMLCHLQRMVSEQCHLLSQFFRELPPAAEFVKTVEFTRLRIQEERTLACLRLLAFLEGKEGEDTLVLSVWDSYAESRQLTLPRTEAAC",
                "length": 1953
            },
            "evidence": [
                {
                    "id": "45236773",
                    "url": "http://www.informatics.jax.org/homology/45236773",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 4,
                "go_terms": [
                    {
                        "name": "tRNA nucleoside ribose methylation",
                        "id": "GO:0002128",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002128",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D3ZVT2",
                                "url": "https://www.uniprot.org/uniprot/D3ZVT2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "lipid homeostasis",
                        "id": "GO:0055088",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D3ZVT2",
                                "url": "https://www.uniprot.org/uniprot/D3ZVT2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "tRNA methylation",
                        "id": "GO:0030488",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D3ZVT2",
                                "url": "https://www.uniprot.org/uniprot/D3ZVT2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of endoplasmic reticulum calcium ion concentration",
                        "id": "GO:0032471",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032471",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D3ZVT2",
                                "url": "https://www.uniprot.org/uniprot/D3ZVT2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "endoplasmic reticulum",
                        "id": "GO:0005783",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D3ZVT2",
                                "url": "https://www.uniprot.org/uniprot/D3ZVT2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "enzyme regulator activity",
                        "id": "GO:0030234",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "D3ZVT2",
                                "url": "https://www.uniprot.org/uniprot/D3ZVT2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 1119,
            "end_pos": 1121,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 1242,
            "end_pos": 1244,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 140,
            "end_pos": 142,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 217,
            "end_pos": 219,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 555,
            "end_pos": 557,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 698,
            "end_pos": 700,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 803,
            "end_pos": 805,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
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