{
    "uniprot_canonical_ac": "D3ZCU8-1",
    "uniprot_ac": "D3ZCU8",
    "uniprot_id": "D3ZCU8_RAT",
    "mass": {
        "chemical_mass": 26584.0,
        "monoisotopic_mass": 26584.0
    },
    "refseq": {
        "ac": "NP_001101727",
        "name": "ras-related protein Rab-33A",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101727"
    },
    "gene_names": [
        {
            "name": "Rab33a",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/D3ZCU8",
            "id": "D3ZCU8"
        },
        {
            "name": "RGD1563280",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101727",
            "id": "NP_001101727"
        },
        {
            "name": "Rab33a",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101727",
            "id": "NP_001101727"
        }
    ],
    "protein_names": [
        {
            "name": "RAB33A, member RAS oncogene family",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "D3ZCU8"
        },
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            "name": "RAB33A, member of RAS oncogene family",
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            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101727",
            "id": "NP_001101727"
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        {
            "annotation": "Atg16L1 regulates not only autophagy in all cell types, but also secretion from dense-core vesicles, presumably by acting as a Rab33A effector, in particular cell types.",
            "evidence": [
                {
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                    "id": "NP_001101727",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101727"
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                    "id": "22740627",
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            "annotation": "Results indicated that Rab33A is a novel component of IPR-stimulated amylase secretion from parotid acinar cells",
            "evidence": [
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                    "id": "NP_001101727",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101727"
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                    "id": "25871792",
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            "annotation": "These data suggest that Rab33a participates in axon outgrowth by mediating anterograde axonal transport of synaptophysin-positive vesicles and their concomitant fusion at the growth cones",
            "evidence": [
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                    "id": "NP_001101727",
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            ]
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    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
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        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
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                    "database": "UniProtKB",
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                    "url": "https://www.uniprot.org/uniprot/D3ZCU8"
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            "common_name": "Rat"
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            "name": "Rab33a",
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                "end_pos": 127694964,
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                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000006698",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000006698"
                    }
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        {
            "id": "ENSRNOG00000006698",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000006698",
            "database": "Bgee",
            "categories": [
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        },
        {
            "id": "cd04115",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04115",
            "database": "CDD",
            "categories": [
                "Protein Classification"
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            "id": "317580",
            "url": "https://www.ncbi.nlm.nih.gov/gene/317580",
            "database": "GeneID",
            "categories": [
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            ]
        },
        {
            "id": "IPR001806",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR005225",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
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            "id": "IPR027417",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
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        {
            "id": "IPR041822",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR041822",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
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            "id": "rno:317580",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:317580",
            "database": "KEGG Pathway",
            "categories": [
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        {
            "id": "CLTVRFC",
            "url": "https://omabrowser.org/oma/group/CLTVRFC/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "8685at2759",
            "url": "http://www.orthodb.org/?query=8685at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR47978:SF30",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47978:SF30",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00071",
            "url": "http://pfam.xfam.org/family/PF00071",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
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        {
            "id": "R-RNO-8854214",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-8854214",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-8873719",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-8873719",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001101727",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101727",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1563280",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1563280",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "D3ZCU8",
            "url": "https://www.uniprot.org/uniprot/D3ZCU8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3ZCU8-1",
            "url": "https://www.uniprot.org/uniprot/D3ZCU8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
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        "sequence": "MAQPILGHGSLQPASAAGLASLELDSSMDQYVQIRIFKIIVIGDSNVGKTCLTFRFCGGTFPDKTEATIGVDFREKTVEIEGEKIKVQVWDTAGQERFRKSMVEHYYRNVHAVVFVYDVTKMTSFTNLKMWIQECNGHAVPPLVPKVLVGNKCDLREQIQVPSNLALKFADAHNMLLFETSAKDPKESQNVESIFMCLACRLKAQKSLLYRDAERQQGKVQTLEFPQEANSKTSCPC",
        "length": 237,
        "header": "tr|D3ZCU8-1|D3ZCU8_RAT Isoform 1 of RAB33A, member RAS oncogene family  OS=Rattus norvegicus OX=10116 GN=Rab33a PE=3 SV=1 CANONICAL=D3ZCU8-1"
    },
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        {
            "isoform_ac": "D3ZCU8-1",
            "url": "",
            "sequence": {
                "sequence": "MAQPILGHGSLQPASAAGLASLELDSSMDQYVQIRIFKIIVIGDSNVGKTCLTFRFCGGTFPDKTEATIGVDFREKTVEIEGEKIKVQVWDTAGQERFRKSMVEHYYRNVHAVVFVYDVTKMTSFTNLKMWIQECNGHAVPPLVPKVLVGNKCDLREQIQVPSNLALKFADAHNMLLFETSAKDPKESQNVESIFMCLACRLKAQKSLLYRDAERQQGKVQTLEFPQEANSKTSCPC",
                "length": 237,
                "header": "tr|D3ZCU8-1|D3ZCU8_RAT Isoform 1 of RAB33A, member RAS oncogene family  OS=Rattus norvegicus OX=10116 GN=Rab33a PE=3 SV=1 CANONICAL=D3ZCU8-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 127706249,
                "end_pos": 127695119,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000008868.5",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000008868.5"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000008868.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000008868.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Atg16L1, an essential factor for canonical autophagy, participates in hormone secretion from PC12 cells independently of autophagic activity.",
            "journal": "Molecular biology of the cell",
            "date": "2012",
            "authors": "Ishibashi K, Uemura T, Waguri S, Fukuda M",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001101727",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101727"
                }
            ],
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                {
                    "type": "PubMed",
                    "id": "22740627",
                    "url": "https://glygen.org/publication/PubMed/22740627"
                }
            ]
        },
        {
            "title": "Rab33a mediates anterograde vesicular transport for membrane exocytosis and axon outgrowth.",
            "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience",
            "date": "2012",
            "authors": "Nakazawa H, Sada T, Toriyama M, Tago K, Sugiura T, Fukuda M, Inagaki N",
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                {
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                    "id": "NP_001101727",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101727"
                }
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                    "type": "PubMed",
                    "id": "22972995",
                    "url": "https://glygen.org/publication/PubMed/22972995"
                }
            ]
        },
        {
            "title": "The small GTPase Rab33A participates in regulation of amylase release from parotid acinar cells.",
            "journal": "Biochemical and biophysical research communications",
            "date": "2015",
            "authors": "Imai A, Tsujimura M, Yoshie S, Fukuda M",
            "evidence": [
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                    "id": "NP_001101727",
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                }
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        },
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            "name": "RAB geranylgeranylation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-8873719",
            "resource": "Reactome",
            "description": "RAB geranylgeranylation"
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            "uniprot_canonical_ac": "P97950-1",
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        },
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            "common_name": "Human"
        }
    ],
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            {
                "name": "Molecular Function",
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                    {
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                        "id": "GO:0003924",
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            "name": "homologset.mgi",
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