{ "uniprot_canonical_ac": "D3Z8E6-1", "uniprot_ac": "D3Z8E6", "uniprot_id": "CAMP1_RAT", "mass": { "chemical_mass": 178525.0, "monoisotopic_mass": 178525.0 }, "refseq": { "ac": "NP_001162021", "name": "calmodulin-regulated spectrin-associated protein 1 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162021" }, "gene_names": [ { "name": "Camsap1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/D3Z8E6", "id": "D3Z8E6" }, { "name": "Camsap1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162021", "id": "NP_001162021" }, { "name": "RGD1565022", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162021", "id": "NP_001162021" } ], "protein_names": [ { "name": "Calmodulin-regulated spectrin-associated protein 1", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "D3Z8E6" }, { "name": "calmodulin-regulated spectrin-associated protein 1 isoform 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162021", "id": "NP_001162021" }, { "name": "calmodulin-regulated spectrin-associated protein 1 isoform X1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006233737", "id": "XP_006233737" } ], "function": [ { "annotation": "CAMSAP-conserved region represents a functional region of CAMSAP1, which links spectrin-binding to neurite outgrowth", "evidence": [ { "database": "RefSeq", "id": "NP_001162021", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162021" }, { "database": "PubMed", "id": "24117850", "url": "https://glygen.org/publication/PubMed/24117850" } ] }, { "annotation": "Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization (PubMed:19508979, PubMed:24117850). Specifically recognizes growing microtubule minus-ends and stabilizes microtubules (By similarity). Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization (By similarity). In contrast to CAMSAP2 and CAMSAP3, tracks along the growing tips of minus-end microtubules without significantly affecting the polymerization rate: binds at the very tip of the microtubules minus-end and acts as a minus-end tracking protein (-TIP) that dissociates from microtubules after allowing tubulin incorporation (By similarity). Through interaction with spectrin may regulate neurite outgrowth (PubMed:24117850).", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6#function" }, { "database": "UniProtKB", "id": "Q5T5Y3", "url": "https://www.uniprot.org/uniprot/Q5T5Y3#function" }, { "database": "PubMed", "id": "19508979", "url": "https://glygen.org/publication/PubMed/19508979" }, { "database": "PubMed", "id": "24117850", "url": "https://glygen.org/publication/PubMed/24117850" } ] } ], "disease": [ { "disease_id": "DOID:0090131", "recommended_name": { "id": "DOID:0090131", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0090131", "name": "complex cortical dysplasia with other brain malformations", "description": "A brain disease characterized by aberrant neuronal migration and disturbed axonal guidance resulting in variable brain malformations." }, "synonyms": [ { "id": "DOID:0090131", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0090131", "name": "CDCBM", "description": "" }, { "id": "MONDO:0013541", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013541", "name": "complex cortical dysplasia with other brain malformations 1", "description": "Any complex cortical dysplasia with other brain malformations in which the cause of the disease is a mutation in the TUBB3 gene." }, { "id": "MONDO:0013541", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013541", "name": "CDCBM1", "description": "" }, { "id": "MONDO:0013541", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013541", "name": "TUBB3 complex cortical dysplasia with other brain malformations", "description": "" }, { "id": "MONDO:0013541", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013541", "name": "complex cortical dysplasia with other brain malformations caused by mutation in TUBB3", "description": "" }, { "id": "MONDO:0013541", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013541", "name": "complex cortical dysplasia with other brain malformations type 1", "description": "" }, { "id": "MONDO:0013541", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013541", "name": "cortical dysgenesis with pontocerebellar hypoplasia due to TUBB3 mutation", "description": "" }, { "id": "MONDO:0013541", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013541", "name": "cortical dysplasia, Complex, with Other brain malformations type 1", "description": "" }, { "id": "MONDO:0013541", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013541", "name": "cortical dysplasia, complex, with other brain malformations 1", "description": "" }, { "id": "MIM:614039", "resource": "MIM", "url": "https://www.omim.org/entry/614039", "name": "Cortical dysplasia, complex, with other brain malformations 1", "description": "Cortical dysplasia, complex, with other brain malformations 1" } ], "evidence": [ { "id": "0090131", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0090131" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "common_name": "Rat" } ], "gene": [ { "name": "Camsap1", "url": "https://www.uniprot.org/uniprot/D3Z8E6", "locus": { "chromosome": "3", "start_pos": 8746176, "end_pos": 8806072, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000017883", "url": "https://www.ensembl.org/id/ENSRNOG00000017883" } ] } } ], "crossref": [ { "id": "ENSRNOG00000017883", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000017883", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "296580", "url": "https://www.ncbi.nlm.nih.gov/gene/296580", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "D3Z8E6", "url": "https://www.ebi.ac.uk/intact/interactors/id:D3Z8E6*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022613", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022613", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:296580", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:296580", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EANHYII", "url": "https://omabrowser.org/oma/group/EANHYII/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "2918432at2759", "url": "http://www.orthodb.org/?query=2918432at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21595", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21595", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21595:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21595:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08683", "url": "http://pfam.xfam.org/family/PF08683", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF11971", "url": "http://pfam.xfam.org/family/PF11971", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF17095", "url": "http://pfam.xfam.org/family/PF17095", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_D3Z8E6", "url": "http://purl.obolibrary.org/obo/PR_D3Z8E6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001162021", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162021", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1565022", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1565022", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2K5T1", "url": "https://www.uniprot.org/uniprot/A0A0G2K5T1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2K5T1-1", "url": "https://www.uniprot.org/uniprot/A0A0G2K5T1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I5ZW13", "url": "https://www.uniprot.org/uniprot/A0A8I5ZW13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I5ZW13-1", "url": "https://www.uniprot.org/uniprot/A0A8I5ZW13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6GHB0", "url": "https://www.uniprot.org/uniprot/A0A8I6GHB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6GHB0-1", "url": "https://www.uniprot.org/uniprot/A0A8I6GHB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D3Z8E6-1", "url": "https://www.uniprot.org/uniprot/D3Z8E6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDAGGRSAAEGWRRMEAPPEGADLVPLDRYDAARAKIAANLQWICAKAYGLDNIPEDLRDPFYIDQYEQEHIKPPVIKLLLSSELYCRVCSLILKGDQAATLQGHQSVIQALSRKGIYVMESDDTPVTDADLSQAPIKMSGHMAMVDALMMAYTVEMISIEKVVASVKRFSTFSASKELPYDLEDAMVFWINKVNLKMREITEKEVKLKQQPLESPAHQKPGLEHAVMHCMLEPVDFARVVRYRREHLSARQSPYFPLLEDLMRDGSDGAALLAVVHYYCPEQMKLDDICLKEVPSMADSLYNIRLLREFSNEHLNKCFYLTLEDMLYAPLVLKPNVMVFIAELFWWFENVKPDFVQPRDIQELKDAKTVLQQKSSRPPVPISNATKRSFLGSPAAMSPADLPPSTQPLTEGSHRYHLHSEEPECLGKGASTFSPSHPLLPLRQKQQKVSQAEEIPDQRHRSNSLTRADGQPRGAAIAWPDKKNRPVSQPTSFALHHAASCDVDPSSGDSISLARSISKDSLASNIIHLTPQNQPHPSAGKTNGKSLLSNVNIEDDEEEELVAIIRTDVSPHSPEIPRTSPQAPGLVASIRSPQRQADTLESKPDSFYLEPLMPAVLRPAKEKQIITKEDERGEGRPRTIMAKRPSEGSQPLVRKKVTGSHGSRDLNRTFTPIPCSEFAASIDPTEVGPQSTEATGEGQPLALGRFDPVPQGQVADGFFLHVGRAEEDEGRWYVGSQSPSSHDSEPWTILRQDSDSDVVDVEDAEQDFIGEDHPVVIPRYAGEEESAKLQEDMKVKEHEDKDDASGRSSPCLSTTSQLSSMSMASGSVKMTSFAERKLQRLNSCETKSSTSSSQKTTPDASESCPAPLTTWRQKREQSPSRHSKDPASLLASELVQLHMQLEEKRRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGKADGAPQPLRPEHFTKEFTQHNGEDLDDGTCKTEGFLVKEEQRDLSDSQDVAFVQLHKPRDPATLHDGEKHRVISAALLEDSVGEVDVNECDLSIEKLNETISTLQQAILKISQQQEQLLMKSPTVPTSGTKNNCQDQKVKAPVHFVEPLSPTGVPGHRKPPRLGQGRNSRSGRPAELKVPKDRQQGCSRSKTPTPSVETLPHSRSLPPSTHPRSPLDPGGELPEKCLFDSYRLHDESNHRTFGLSSCKDANIVSEQMNFKEGLDTSVQEAELSSSAITGKEHTPMEEPLRSKASLIEVDLSDLKAPDEDGEVVGHESSLELGGESDQKPGVGFFFKDEQKAEDELAKKRAAFLLKQQRKAEEARARKQQLEAEVELKRDEARRKAEEDRLRKEEEKARRELIKQEYLRRKQQQALEEQGLGKPKSKPKKPRPKSVHREESCSDSGTKCSSTPDNLSQTHSGSSLSLASAATTEPESVHSGGTPSHRVESLEALPILSRNPSRSTDRDWETASAASSLASVAEYTGPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEELEKCDANHYIILFRDAGCQFRALYCYQPDTEEIYKLTGTGPKSITKKMIDKLYKYSSDRKQFNLIPAKTMSVSVDALTIHNHLWQPKRPTVPKKTQTRK", "length": 1604, "header": "sp|D3Z8E6-1|CAMP1_RAT Isoform 1 of Calmodulin-regulated spectrin-associated protein 1 OS=Rattus norvegicus OX=10116 GN=Camsap1 PE=1 SV=2 CANONICAL=D3Z8E6-1" }, "isoforms": [ { "isoform_ac": "A0A0G2K5T1-1", "url": "", "sequence": { "sequence": "METEPRLRMRPVTGPRRAFAWCRFKSCCSGSGPDNIPEDLRDPFYIDQYEQEHIKPPVIKLLLSSELYCRVCSLILKGDQAATLQGHQSVIQALSRKGIYVMESDDTPVTDADLSQAPIKMSGHMAMVDALMMAYTVEMISIEKVVASVKRFSTFSASKELPYDLEDAMVFWINKVNLKMREITEKEVKLKQQPLESPAHQKRPFSFYQLQVRYRREHLSARQSPYFPLLEDLMRDGSDGAALLAVVHYYCPEQMKLDDICLKEVPSMADSLYNIRLLREFSNEHLNKCFYLTLEDMLYAPLVLKPNVMVFIAELFWWFENVKPDFVQPRDIQELKDAKTVLQQKSSRPPVPISNATKRSFLGSPAAMSPADLPPSTQPLTEGSHRYHLHSEEPECLGKGASTFSPSHPLLPLRQKQQKVSQAEEIPDQRHRSNSLTRADGQPRGAAIAWPDKKNRPVSQPTSFALHHAASCDVDPSSGDSISLARSISKDSLASNIIHLTPQNQPHPSAGKTNGKSLLSNVNIEDDEEEELVAIIRTDVSPHSPEIPRTSPQAPGLVASIRSPQRQADTLESKPDSFYLEPLMPAVLRPAKEKQIITKEDERGEGRPRTIMAKRPSEGSQPLVRKKVTGSHGSRDLNRTFTPIPCSEFAASIDPTEVGPQSTEATGEGQPLALGRFDPVPQGQVADGFFLHVGRAEEDEGRWYVGSQSPSSHDSEPWTILRQDSDSDVVDVEDAEQDFIGEDHPVVIPRYAGEEESAKLQEDMKVKEHEDKDDASGRSSPCLSTTSQLSSMSMASGSVKMTSFAERKLQRLNSCETKSSTSSSQKTTPDASESCPAPLTTWRQKREQSPSRHSKDPASLLASELVQLHMQLEEKRRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGKADGAPQPLRPEHFTKEFTQHNGEDLDDGTCKTEGFLVKEEQRDLSDSQDVAFVQLHKPRDPATLHDGEKHRVISAALLEDSVGEVDVNECDLSIEKLNETISTLQQAILKISQQQEQLLMKSPTVPTSGTKNNCQDQKVKAPVHFVEPLSPTGVPGHRKPPRLGQGRNSRSGRPAELKVPKDRQQGCSRSKTPTPSVETLPHSRSLPPSTHPRSPLDPGGELPEKCLFDSYRLHDESNHRTFGLSSCKDANIVSEQMNFKEGLDTSVQEAELSSSAITGKEHTPMEEPLRSKASLIEVDLSDLKAPDEDGEVVGHESSLELGGESDQKPGVGFFFKDEQKAEDELAKKRAAFLLKQQRKAEEARARKQQLEAEVELKRDEARRKAEEDRLRKEEEKARRELIKQEYLRRKQQQALEEQGLGKPKSKPKKPRPKSVHREESCSDSGTKCSSTPDNLSQTHSGSSLSLASAATTEPESVHSGGTPSHRVESLEALPILSRNPSRSTDRDWETASAASSLASVAEYTGPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEELEKCDANHYIILFRDAGCQFRALYCYQPDTEEIYKLTGTGPKSITKKMIDKLYKYSSDRKQFNLIPAKTMSVSVDALTIHNHLWQPKRPTVPKKTQTRK", "length": 1574, "header": "tr|A0A0G2K5T1-1|A0A0G2K5T1_RAT Computationally mapped isoform of Calmodulin regulated spectrin-associated protein 1 OS=Rattus norvegicus OX=10116 GN=Camsap1 PE=1 SV=2 CANONICAL=D3Z8E6-1" }, "locus": { "chromosome": "3", "start_pos": 8805146, "end_pos": 8747654, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000078020.2", "url": "https://www.ensembl.org/id/ENSRNOT00000078020.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000073547.2", "url": "https://www.ensembl.org/id/ENSRNOP00000073547.2" } ] } }, { "isoform_ac": "A0A8I5ZW13-1", "url": "", "sequence": { "sequence": "MVDAGGRSAAEGWRRMEAPPEGADLVPLDRYDAARAKIAANLQWICAKAYGLDNIPEDLRDPFYIDQYEQEHIKPPVIKLLLSSELYCRVCSLILKGDQAATLQGHQSVIQALSRKGIYVMESDDTPVTDADLSQAPIKMSGHMAMVDALMMAYTVEMISIEKVVASVKRFSTFSASKELPYDLEDAMVFWINKVNLKMREITEKEVKLKQQPLESPAHQKVRYRREHLSARQSPYFPLLEDLMRDGSDGAALLAVVHYYCPEQMKLDDICLKEVPSMADSLYNIRLLREFSNEHLNKCFYLTLEDMLYAPLVLKPNVMVFIAELFWWFENVKPDFVQPRDIQELKDAKTVLQQKSSRPPVPISNATKRSFLGSPAAMSPADLPPSTQPLTEGSHRYHLHSEEPECLGKGASTFSPSHPLLPLRQKQQKVSQAEEIPDQRHRSNSLTRADGQPRGAAIAWPDKKNRPVSQPTSFALHHAASCDVDPSSGDSISLARSISKDSLASNIIHLTPQNQPHPSAGKTNGKSLLSNVNIEDDEEEELVAIIRTDVSPHSPEIPRTSPQAPGLVASIRSPQRQADTLESKPDSFYLEPLMPAVLRPAKEKQIITKEDERGEGRPRTIMAKRPSEGSQPLVRKKVTGSHGSRDLNRTFTPIPCSEFAASIDPTEVGPQSTEATGEGQPLALGRFDPVPQGQVADGFFLHVGRAEEDEGRWYVGSQSPSSHDSEPWTILRQDSDSDVVDVEDAEQDFIGEDHPVVIPRYAGEEESAKLQEDMKVKEHEDKDDASGRSSPCLSTTSQLSSMSMASGSVKMTSFAERKLQRLNSCETKSSTSSSQKTTPDASESCPAPLTTWRQKREQSPSRHSKDPASLLASELVQLHMQLEEKRRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGKADGAPQPLRPEHFTKEFTQHNGEDLDDGTCKTEGFLVKEEQRDLSDSQDVAFVQLHKPRDPATLHDGEKHRVISAALLEDSVGEVDVNECDLSIEKLNETISTLQQAILKISQQQEQLLMKSPTVPTSGTKNNCQDQKVKAPVHFVEPLSPTGVPGHRKPPRLGQGRNSRSGRPAELKVPKDRQQGCSRSKTPTPSVETLPHSRSLPPSTHPRSPLDPGGELPEKCLFDSYRLHDESNHRTFGLSSCKDANIVSEQMNFKEGLDTSVQEAELSSSAITGKEHTPMEEPLRSKASLIEVDLSDLKAPDEDGEVVGHESSLELGGESDQKPGVGFFFKDEQKAEDELAKKRAAFLLKQQRKAEEARARKQQLEAEVELKRDEARRKAEEDRLRKEEEKARRELIKQEYLRRKQQQALEEQGLGKPKSKPKKPRPKSVHREESCSDSGTKCSSTPDNLSQTHSGSSLSLASAATTEPESVHSGGTPSHRVESLEALPILSRNPSRSTDRDWETASAASSLASVAEYTGPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEELEKCDANHYIILFRDAGCQFRALYCYQPDTEEIYKLTGTGPKSITKKMIDKLYKYSSDRKQFNLIPAKTMSVSVDALTIHNHLWQPKRPTVPKKTQTRK", "length": 1584, "header": "tr|A0A8I5ZW13-1|CAMP1_RAT Computationally mapped isoform of Calmodulin-regulated spectrin-associated protein 1 OS=Rattus norvegicus OX=10116 GN=Camsap1 PE=1 SV=1 CANONICAL=D3Z8E6-1" }, "locus": { "chromosome": "3", "start_pos": 8805736, "end_pos": 8747654, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000099628.1", "url": "https://www.ensembl.org/id/ENSRNOT00000099628.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000081912.1", "url": "https://www.ensembl.org/id/ENSRNOP00000081912.1" } ] } }, { "isoform_ac": "A0A8I6GHB0-1", "url": "", "sequence": { "sequence": "MVDAGGRSAAEGWRRMEAPPEGADLVPLDRYDAARAKIAANLQWICAKAYGLDNIPEDLRDPFYIDQYEQEHIKPPVIKLLLSSELYCRVCSLILKGDQAATLQGHQSVIQALSRKGIYVMESDDTPVTDADLSQAPIKMSGHMAMVDALMMAYTVEMISIEKVVASVKRFSTFSASKELPYDLEDAMVFWINKVNLKMREITEKEVKLKQQPLESPAHQKSPSKWYWKLVPVRYRREHLSARQSPYFPLLEDLMRDGSDGAALLAVVHYYCPEQMKLDDICLKEVPSMADSLYNIRLLREFSNEHLNKCFYLTLEDMLYAPLVLKPNVMVFIAELFWWFENVKPDFVQPRDIQELKDAKTVLQQKSSRPPVPISNATKRSFLGSPAAMSPADLPPSTQPLTEGSHRYHLHSEEPECLGKGASTFSPSHPLLPLRQKQQKVSQAEEIPDQRHRSNSLTRADGQPRGAAIAWPDKKNRPVSQPTSFALHHAASCDVDPSSGDSISLARSISKDSLASNIIHLTPQNQPHPSAGKTNGKSLLSNVNIEDDEEEELVAIIRTDVSPHSPEIPRTSPQAPGLVASIRSPQRQADTLESKPDSFYLEPLMPAVLRPAKEKQIITKEDERGEGRPRTIMAKRPSEGSQPLVRKKVTGSHGSRDLNRTFTPIPCSEFAASIDPTEVGPQSTEATGEGQPLALGRFDPVPQGQVADGFFLHVGRAEEDEGRWYVGSQSPSSHDSEPWTILRQDSDSDVVDVEDAEQDFIGEDHPVVIPRYAGEEESAKLQEDMKVKEHEDKDDASGRSSPCLSTTSQLSSMSMASGSVKMTSFAERKLQRLNSCETKSSTSSSQKTTPDASESCPAPLTTWRQKREQSPSRHSKDPASLLASELVQLHMQLEEKRRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGKADGAPQPLRPEHFTKEFTQHNGEDLDDGTCKTEGFLVKEEQRDLSDSQDVAFVQLHKPRDPATLHDGEKHRVISAALLEDSVGEVDVNECDLSIEKLNETISTLQQAILKISQQQEQLLMKSPTVPTSGTKNNCQDQKVKAPVHFVEPLSPTGVPGHRKPPRLGQGRNSRSGRPAELKVPKDRQQGCSRSKTPTPSVETLPHSRSLPPSTHPRSPLDPGGELPEKCLFDSYRLHDESNHRTFGLSSCKDANIVSEQMNFKEGLDTSVQEAELSSSAITGKEHTPMEEPLRSKASLIEVDLSDLKAPDEDGEVVGHESSLELGGESDQKPGVGFFFKDEQKAEDELAKKRAAFLLKQQRKAEEARARKQQLEAEVELKRDEARRKAEEDRLRKEEEKARRELIKQEYLRRKQQQALEEQGLGKPKSKPKKPRPKSVHREESCSDSGTKCSSTPDNLSQTHSGSSLSLASAATTEPESVHSGGTPSHRVESLEALPILSRNPSRSTDRDWETASAASSLASVAEYTGPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEELEKCDANHYIILFRDAGCQFRALYCYQPDTEEIYKLTGTGPKSITKKMIDKLYKYSSDRKQFNLIPAKTMSVSVDALTIHNHLWQPKRPTVPKKTQTRK", "length": 1595, "header": "tr|A0A8I6GHB0-1|CAMP1_RAT Computationally mapped isoform of Calmodulin-regulated spectrin-associated protein 1 OS=Rattus norvegicus OX=10116 GN=Camsap1 PE=1 SV=1 CANONICAL=D3Z8E6-1" }, "locus": { "chromosome": "3", "start_pos": 8805736, "end_pos": 8747654, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000101799.1", "url": "https://www.ensembl.org/id/ENSRNOT00000101799.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000088653.1", "url": "https://www.ensembl.org/id/ENSRNOP00000088653.1" } ] } }, { "isoform_ac": "D3Z8E6-1", "url": "", "sequence": { "sequence": "MVDAGGRSAAEGWRRMEAPPEGADLVPLDRYDAARAKIAANLQWICAKAYGLDNIPEDLRDPFYIDQYEQEHIKPPVIKLLLSSELYCRVCSLILKGDQAATLQGHQSVIQALSRKGIYVMESDDTPVTDADLSQAPIKMSGHMAMVDALMMAYTVEMISIEKVVASVKRFSTFSASKELPYDLEDAMVFWINKVNLKMREITEKEVKLKQQPLESPAHQKPGLEHAVMHCMLEPVDFARVVRYRREHLSARQSPYFPLLEDLMRDGSDGAALLAVVHYYCPEQMKLDDICLKEVPSMADSLYNIRLLREFSNEHLNKCFYLTLEDMLYAPLVLKPNVMVFIAELFWWFENVKPDFVQPRDIQELKDAKTVLQQKSSRPPVPISNATKRSFLGSPAAMSPADLPPSTQPLTEGSHRYHLHSEEPECLGKGASTFSPSHPLLPLRQKQQKVSQAEEIPDQRHRSNSLTRADGQPRGAAIAWPDKKNRPVSQPTSFALHHAASCDVDPSSGDSISLARSISKDSLASNIIHLTPQNQPHPSAGKTNGKSLLSNVNIEDDEEEELVAIIRTDVSPHSPEIPRTSPQAPGLVASIRSPQRQADTLESKPDSFYLEPLMPAVLRPAKEKQIITKEDERGEGRPRTIMAKRPSEGSQPLVRKKVTGSHGSRDLNRTFTPIPCSEFAASIDPTEVGPQSTEATGEGQPLALGRFDPVPQGQVADGFFLHVGRAEEDEGRWYVGSQSPSSHDSEPWTILRQDSDSDVVDVEDAEQDFIGEDHPVVIPRYAGEEESAKLQEDMKVKEHEDKDDASGRSSPCLSTTSQLSSMSMASGSVKMTSFAERKLQRLNSCETKSSTSSSQKTTPDASESCPAPLTTWRQKREQSPSRHSKDPASLLASELVQLHMQLEEKRRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGKADGAPQPLRPEHFTKEFTQHNGEDLDDGTCKTEGFLVKEEQRDLSDSQDVAFVQLHKPRDPATLHDGEKHRVISAALLEDSVGEVDVNECDLSIEKLNETISTLQQAILKISQQQEQLLMKSPTVPTSGTKNNCQDQKVKAPVHFVEPLSPTGVPGHRKPPRLGQGRNSRSGRPAELKVPKDRQQGCSRSKTPTPSVETLPHSRSLPPSTHPRSPLDPGGELPEKCLFDSYRLHDESNHRTFGLSSCKDANIVSEQMNFKEGLDTSVQEAELSSSAITGKEHTPMEEPLRSKASLIEVDLSDLKAPDEDGEVVGHESSLELGGESDQKPGVGFFFKDEQKAEDELAKKRAAFLLKQQRKAEEARARKQQLEAEVELKRDEARRKAEEDRLRKEEEKARRELIKQEYLRRKQQQALEEQGLGKPKSKPKKPRPKSVHREESCSDSGTKCSSTPDNLSQTHSGSSLSLASAATTEPESVHSGGTPSHRVESLEALPILSRNPSRSTDRDWETASAASSLASVAEYTGPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEELEKCDANHYIILFRDAGCQFRALYCYQPDTEEIYKLTGTGPKSITKKMIDKLYKYSSDRKQFNLIPAKTMSVSVDALTIHNHLWQPKRPTVPKKTQTRK", "length": 1604, "header": "sp|D3Z8E6-1|CAMP1_RAT Isoform 1 of Calmodulin-regulated spectrin-associated protein 1 OS=Rattus norvegicus OX=10116 GN=Camsap1 PE=1 SV=2 CANONICAL=D3Z8E6-1" }, "locus": { "chromosome": "3", "start_pos": 8805736, "end_pos": 8747654, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000024163", "url": "https://www.ensembl.org/id/ENSRNOT00000024163" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000024163", "url": "https://www.ensembl.org/id/ENSRNOP00000024163" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 1090, "end_pos": 1090, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "D3Z8E6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/D3Z8E6" } ], "site_lbl": "Ser1090" }, { "start_pos": 1154, "end_pos": 1154, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "D3Z8E6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/D3Z8E6" } ], "site_lbl": "Ser1154" }, { "start_pos": 1400, "end_pos": 1400, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "site_lbl": "Ser1400" }, { "start_pos": 1429, "end_pos": 1429, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "D3Z8E6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/D3Z8E6" } ], "site_lbl": "Ser1429" }, { "start_pos": 1539, "end_pos": 1539, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "site_lbl": "Tyr1539" }, { "start_pos": 216, "end_pos": 216, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "site_lbl": "Ser216" }, { "start_pos": 390, "end_pos": 390, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "site_lbl": "Ser390" }, { "start_pos": 394, "end_pos": 394, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "site_lbl": "Ser394" }, { "start_pos": 435, "end_pos": 435, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "site_lbl": "Ser435" }, { "start_pos": 531, "end_pos": 531, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "site_lbl": "Thr531" }, { "start_pos": 571, "end_pos": 571, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "site_lbl": "Ser571" }, { "start_pos": 574, "end_pos": 574, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "D3Z8E6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/D3Z8E6" } ], "site_lbl": "Ser574" }, { "start_pos": 581, "end_pos": 581, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "site_lbl": "Ser581" }, { "start_pos": 593, "end_pos": 593, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "site_lbl": "Ser593" }, { "start_pos": 607, "end_pos": 607, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "site_lbl": "Ser607" }, { "start_pos": 647, "end_pos": 647, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "site_lbl": "Ser647" }, { "start_pos": 739, "end_pos": 739, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "site_lbl": "Ser739" }, { "start_pos": 745, "end_pos": 745, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "site_lbl": "Ser745" }, { "start_pos": 755, "end_pos": 755, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "D3Z8E6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/D3Z8E6" } ], "site_lbl": "Ser755" }, { "start_pos": 757, "end_pos": 757, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "D3Z8E6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/D3Z8E6" } ], "site_lbl": "Ser757" } ], "glycation": [], "keywords": [], "publication": [ { "title": "A new monoclonal antibody, A3B10, specific for astrocyte-lineage cells recognizes calmodulin-regulated spectrin-associated protein 1 (Camsap1).", "journal": "J. Neurosci. Res.", "date": "2009", "authors": "Watanabe K., Yamamoto M., Yoshimura K., Ueki T., Kitada M., Asou H., Shimoda Y., Nakahara J., Seiwa C., Ishige A.", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "reference": [ { "type": "PubMed", "id": "18756519", "url": "https://glygen.org/publication/PubMed/18756519" } ] }, { "title": "The CKK domain (DUF1781) binds microtubules and defines the CAMSAP/ssp4 family of animal proteins.", "journal": "Mol. Biol. Evol.", "date": "2009", "authors": "Baines AJ, Bignone PA, King MD, Maggs AM, Bennett PM, Pinder JC, Phillips GW", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "reference": [ { "type": "PubMed", "id": "19508979", "url": "https://glygen.org/publication/PubMed/19508979" } ] }, { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nature communications", "date": "2012", "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" }, { "database": "UniProtKB", "id": "A0A0G2K5T1", "url": "https://www.uniprot.org/uniprot/A0A0G2K5T1" }, { "database": "iPTMnet", "id": "D3Z8E6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/D3Z8E6" } ], "reference": [ { "type": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] }, { "title": "A conserved sequence in CAMSAP1 (calmodulin regulated spectrin-associated protein 1) links its interaction with spectrin and calmodulin to neurite outgrowth.", "journal": "J. Neurochem.", "date": "2014", "authors": "King MD, Phillips GW, Bignone PA, Hayes NV, Pinder JC, Baines AJ", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" }, { "database": "RefSeq", "id": "NP_001162021", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162021" } ], "reference": [ { "type": "PubMed", "id": "24117850", "url": "https://glygen.org/publication/PubMed/24117850" } ] } ], "pathway": [ { "id": "rno:296580", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:296580", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2AHC3-1", "protein_name": "Calmodulin-regulated spectrin-associated protein 1", "gene_name": "Camsap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDAGGRCAAEGWRRMEAPPEGADLVPLDRYDAARAKIAANLQWICAKAYGLDNIPEDLRDPFYIDQYEQEHIKPPVIKLLLSSELYCRVCSLILKGDQVATLQGHQSVIQALSRKGIYVMESDDTPVTDADLSQAPIKMSGHMAMVDALMMAYTVEMISIEKVVASVKRFSTFSASKELPYDLEDAMVFWINKVNLKMREITEKEVKLKQQPLESPAHQKVRYRREHLSARQSPYFPLLEDLMRDGSDGAALLAVVHYYCPEQMKLDDICLKEVPSMADSLYNIRLLREFSNEHLNKCFYLTLEDMLYAPLVLKPNVMVFIAELFWWFENVKPDFVQPRDIQELKDAKTVLQQKSSRPPVPISNATKRSFLGSPAAMSPADQPPSTQPLAEGSHRYHLHSEEPECLGKGASTFSPSHPLLPLRQKQQKVSQTEEIPDQRHRSNSLTRVDGQPRGAIGAWPDKKNRPVSQPTSFALHHAASCDVDPSSGDSVSLARSISKDSLASNIIHLTPQNQPHPSAGKSNGKSLLSNVNIEDEDEELVAIIRTDVSPPSPQMPRTSPQAPGLVASIRSPQRQADTLESKPDSFYLEPLMPAVLRPAKEKQITTKEDERGEGRPRTIMAKRPSEGSQPMVRKKVSGGHGSRDLNRTFTPIPCSEFAASIDLAEVGPQSAEATGEGQPLALGRFDTLPQGQAADGFFLHVGRAEEDEGRWYVGSQSPSSHDSEPWTILRQDSDSDVVDVEDTEQDFIGEDHPVVIPRYAGEEESAKLQEDMKVKEHEDKDDASGRSSPCLSTTSQLSSMSMASGSVKMTSFAERKLQRLNSCETKSSTSSSQKTTPDASESCPAPLTTWRQKREQSPGRHSKDPASLLASELVQLHMQLEEKRRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGKADGAPQPLRPEHFTKEFTQHNGEDLDDGTCKTEGFLVKEEQRDLSDAQDVAFVQLHKPRDPAALHDGEKHRMISTALLEDSVGEVDVNECDLSIEKLNETISTLQQAILKISQQQEQLLMKSPTVPTPGTKNNCQDQKIKAPVHFVEPLSPTGVPGHRKPPRLGQGRNSRSGRPAELKVPKDRQQGCSRSKTPTPSVETLPQSRSLPPSTHPRSPSDPGGELPEKCLFDSYRLHDESNHRTFVLSSCKDANIVSEQVNFKEGLDTSVKEAGLSSSTITGKEHTPVEEPLRSKASLIEVDLSDLKAPDEDGEVVGHESSVELGGDSDQKPGVGFFFKDEQKAEDELAKKRAAFLLKQQRKAEEARARKQQLEAEVELKRDEARRKAEEDRLRKEEEKARRELIKQEYLRRKQQQALEEQGLGKPKSKPKKPRPKSVHREESYSDSGTKCSSTHNLSQTHSGSSLSLASAATTEPESVYSGGTPSHRVESLEALPILSRNPSRSTDRDWETASAASSLASVAEYTGPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILELEKCDANHYIILFRDAGCQFRALYCYQPDTEEIYKLTGTGPKSITKKMIDKLYKYSSDRKQFNLIPAKTMSVSVDALTIHNHLWQPKRPTVPKKTQTRK", "length": 1581 }, "evidence": [ { "id": "45228084", "url": "http://www.informatics.jax.org/homology/45228084", "database": "MGI" } ], "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5T5Y3-1", "protein_name": "Calmodulin-regulated spectrin-associated protein 1", "gene_name": "CAMSAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVDASGRAAAEGWRKMEAPPDGAADLVPLDRYDAARAKIAANLQWICAKAYGRDNIPEDLRDPFYVDQYEQEHIKPPVIKLLLSSELYCRVCSLILKGDQVAALQGHQSVIQALSRKGIYVMESDDTPVTESDLSRAPIKMSAHMAMVDALMMAYTVEMISIEKVVASVKRFSTFSASKELPYDLEDAMVFWINKVNLKMREITEKEVKLKQQLLESPAHQKVRYRREHLSARQSPYFPLLEDLMRDGSDGAALLAVIHYYCPEQMKLDDICLKEVTSMADSLYNIRLLREFSNEYLNKCFYLTLEDMLYAPLVLKPNVMVFIAELFWWFENVKPDFVQPRDVQELKDAKTVLHQKSSRPPVPISNATKRSFLGSPAAGTLAELQPPVQLPAEGCHRHYLHPEEPEYLGKGTAAFSPSHPLLPLRQKQQKSIQGEDIPDQRHRSNSLTRVDGQPRGAAIAWPEKKTRPASQPTPFALHHAASCEVDPSSGDSISLARSISKDSLASNIVNLTPQNQPHPTATKSHGKSLLSNVSIEDEEEELVAIVRADVVPQQADPEFPRASPRALGLTANARSPQGQLDTSESKPDSFFLEPLMPAVLKPAKEKQVITKEDERGEGRPRSIVSRRPSEGPQPLVRRKMTGSRDLNRTFTPIPCSEFPMGIDPTETGPLSVETAGEVCGGPLALGGFDPFPQGPSTDGFFLHVGRADEDTEGRLYVSCSKSPNSHDSEPWTLLRQDSDSDVVDIEEAEHDFMGEAHPVVFSRYIGEEESAKLQEDMKVKEHEDKDDASGRSSPCLSTASQMSSVSMASGSVKMTSFAERKLQRLNSCETKSSTSSSQKTTPDASESCPAPLTTWRQKREQSPSQHGKDPASLLASELVQLHMQLEEKRRAIEAQKKKMEALSARQRLKLGKAAFLHVVKKGKAEAAPPLRPEHFAKEYSQHNGEDCGDAVSKTEDFLVKEEQREELLHEPQDVDKESLAFAQQHKAKDPVALHELERNKVISAALLEDTVGEVVDVNECDLSIEKLNETISTLQQAILKISQQQEQLLMKSPTVPVPGSKNNSQDHKVKAPVHFVEPLSPTGVAGHRKAPRLGQGRNSRSGRPAELKVPKDRPQGSSRSKTPTPSVETLPHLRPFPASSHPRTPTDPGLDSALEPSGDPHGKCLFDSYRLHDESNQRTLTLSSSKDANILSEQMSLKEVLDASVKEVGSSSSDVSGKESVPVEEPLRSRASLIEVDLSDLKAPDEDGELVSLDGSADLVSEGDQKPGVGFFFKDEQKAEDELAKKRAAFLLKQQRKAEEARVRKQQLEAEVELKRDEARRKAEEDRVRKEEEKARRELIKQEYLRRKQQQILEEQGLGKPKSKPKKPRPKSVHREESCSDSGTKCSSTPDNLSRTQSGSSLSLASAATTEPESVHSGGTPSQRVESMEALPILSRNPSRSTDRDWETASAASSLASVAEYTGPKLFKEPSSKSNKPIIHNAISHCCLAGKVNEPHKNSILEELEKCDANHYIILFRDAGCQFRALYCYYPDTEEIYKLTGTGPKNITKKMIDKLYKYSSDRKQFNLIPAKTMSVSVDALTIHNHLWQPKRPAVPKKAQTRK", "length": 1602 }, "evidence": [ { "id": "45228084", "url": "http://www.informatics.jax.org/homology/45228084", "database": "MGI" }, { "id": "D3Z8E6", "url": "https://omabrowser.org/oma/group/D3Z8E6/", "database": "OMA" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "pmid": "" }, { "name": "spectrin binding", "id": "GO:0030507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030507", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "pmid": "" }, { "name": "microtubule minus-end binding", "id": "GO:0051011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051011", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "pmid": "" }, { "name": "microtubule minus-end", "id": "GO:0036449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036449", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "pmid": "" }, { "name": "regulation of microtubule polymerization", "id": "GO:0031113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031113", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "pmid": "" }, { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "pmid": "" }, { "name": "regulation of cell morphogenesis", "id": "GO:0022604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022604", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "D3Z8E6", "url": "https://www.uniprot.org/uniprot/D3Z8E6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1038, "end_pos": 1040, "annotation": "n_glycosylation_sequon" 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