{ "uniprot_canonical_ac": "D3Z0M9-1", "uniprot_ac": "D3Z0M9", "uniprot_id": "D3Z0M9_MOUSE", "mass": { "chemical_mass": 95495.0, "monoisotopic_mass": 95495.0 }, "refseq": { "ac": "NP_001074450", "name": "probable ATP-dependent RNA helicase DDX23", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074450" }, "gene_names": [ { "name": "Ddx23", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/D3Z0M9", "id": "D3Z0M9" }, { "name": "3110082M05Rik; 4921506D17Rik", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074450", "id": "NP_001074450" }, { "name": "Ddx23", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074450", "id": "NP_001074450" } ], "protein_names": [ { "name": "RNA helicase", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "D3Z0M9" }, { "name": "3.6.4.13", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "D3Z0M9" }, { "name": "DEAD (Asp-Glu-Ala-Asp) box polypeptide 23", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074450", "id": "NP_001074450" }, { "name": "probable ATP-dependent RNA helicase DDX23", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074450", "id": "NP_001074450" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "D3Z0M9", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Ddx23", "url": "https://www.uniprot.org/uniprot/D3Z0M9", "locus": { "chromosome": "15", "start_pos": 98543015, "end_pos": 98560775, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000003360", "url": "https://www.ensembl.org/id/ENSMUSG00000003360" } ] } } ], "crossref": [ { "id": "ENSMUSG00000003360", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000003360", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17945", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17945", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18787", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18787", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "74351", "url": "https://www.ncbi.nlm.nih.gov/gene/74351", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:74351", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:74351", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "1921601", "url": "http://www.informatics.jax.org/marker/MGI:1921601", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "KKFNFEW", "url": "https://omabrowser.org/oma/group/KKFNFEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "5487240at2759", "url": "http://www.orthodb.org/?query=5487240at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47958:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47958:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "http://pfam.xfam.org/family/PF00270", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00271", "url": "http://pfam.xfam.org/family/PF00271", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-72163", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-72165", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-72165", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_001074450", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074450", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "D3Z0M9", "url": "https://www.uniprot.org/uniprot/D3Z0M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D3Z0M9-1", "url": "https://www.uniprot.org/uniprot/D3Z0M9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E0CXN3", "url": "https://www.uniprot.org/uniprot/E0CXN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E0CXN3-1", "url": "https://www.uniprot.org/uniprot/E0CXN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGELADKKDRDASPKEERKRSRTPERDRDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSVERERRHKERERDKERDRSKKERERDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKGDEDEHGDKRPKIQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQKMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA", "length": 819, "header": "tr|D3Z0M9-1|D3Z0M9_MOUSE Isoform 1 of RNA helicase OS=Mus musculus OX=10090 GN=Ddx23 PE=1 SV=1 CANONICAL=D3Z0M9-1" }, "isoforms": [ { "isoform_ac": "D3Z0M9-1", "url": "", "sequence": { "sequence": "MAGELADKKDRDASPKEERKRSRTPERDRDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSVERERRHKERERDKERDRSKKERERDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKGDEDEHGDKRPKIQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQKMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA", "length": 819, "header": "tr|D3Z0M9-1|D3Z0M9_MOUSE Isoform 1 of RNA helicase OS=Mus musculus OX=10090 GN=Ddx23 PE=1 SV=1 CANONICAL=D3Z0M9-1" }, "locus": { "chromosome": "15", "start_pos": 98556316, "end_pos": 98543678, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000003450.15", "url": "https://www.ensembl.org/id/ENSMUST00000003450.15" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000003450.9", "url": "https://www.ensembl.org/id/ENSMUSP00000003450.9" } ] } }, { "isoform_ac": "E0CXN3-1", "url": "", "sequence": { "sequence": "MAGELADKKDRDASPKEERKRSRTPERDRDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSVERERRHKERERDK", "length": 80, "header": "tr|E0CXN3-1|D3Z0M9_MOUSE Computationally mapped isoform of RNA helicase OS=Mus musculus OX=10090 GN=Ddx23 PE=1 SV=1 CANONICAL=D3Z0M9-1" }, "locus": { "chromosome": "15", "start_pos": 98556316, "end_pos": 98554560, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000162384.2", "url": "https://www.ensembl.org/id/ENSMUST00000162384.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000125168.2", "url": "https://www.ensembl.org/id/ENSMUSP00000125168.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "mmu:74351", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:74351", "resource": "KEGG Pathway" }, { "id": "R-MMU-72163", "name": "mRNA Splicing - Major Pathway", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-MMU-72165", "name": "mRNA Splicing - Minor Pathway", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9BUQ8-1", "protein_name": "Probable ATP-dependent RNA helicase DDX23", "gene_name": "DDX23", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGELADKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA", "length": 820 }, "evidence": [ { "id": "45237653", "url": "http://www.informatics.jax.org/homology/45237653", "database": "MGI" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "D3Z0M9", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D3Z0M9", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "D3Z0M9", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "D3Z0M9", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "D3Z0M9", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "D3Z0M9", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "D3Z0M9", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "D3Z0M9", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "D3Z0M9", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ], "pmid": "" }, { "name": "U5 snRNP", "id": "GO:0005682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005682", "evidence": [ { "database": "UniProtKB", "id": "D3Z0M9", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "D3Z0M9", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "D3Z0M9", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ], "pmid": "" }, { "name": "R-loop processing", "id": "GO:0062176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062176", "evidence": [ { "database": "UniProtKB", "id": "D3Z0M9", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-MMU-75079", "name": "Formation of AT-AC C complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "D3Z0M9-1", "P08775-1", "Q810A7-1", "Q8CFI7-1", "Q6P4T2-1" ], "evidence": [ { "id": "R-MMU-75079", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-75079" } ] }, { "id": "R-MMU-75081", "name": "Formation of AT-AC B Complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "D3Z0M9-1", "P08775-1", "Q810A7-1", "Q8CFI7-1", "Q6P4T2-1" ], "evidence": [ { "id": "R-MMU-75081", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-75081" } ] }, { "id": "R-MMU-75082", "name": "ATAC spliceosome mediated Lariat formation,5' splice site cleavage", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "D3Z0M9-1", "P08775-1", "Q810A7-1", "Q8CFI7-1", "Q6P4T2-1" ], "evidence": [ { "id": "R-MMU-75082", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-75082" } ] }, { "id": "R-MMU-75083", "name": "ATAC spliceosome mediated 3' splice site cleavage, exon ligation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "D3Z0M9-1", "P08775-1", "Q810A7-1", "Q8CFI7-1", "Q6P4T2-1" ], "evidence": [ { "id": "R-MMU-75083", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-75083" } ] }, { "id": "R-MMU-9770142", "name": "Formation of the Spliceosomal B complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-MMU-8867895", "R-MMU-8867897", "R-MMU-8867887", "R-MMU-8867889" ], "output_participant_list": [ "R-MMU-4615999", "R-MMU-6806778", "R-MMU-6806793", "R-MMU-72049", "R-MMU-8867890", "R-MMU-9769526", "R-MMU-71879", "R-MMU-9769525", "R-MMU-9770250", "R-MMU-9770254" ], "enzyme_list": [ "D3Z0M9-1", "O70133-1", "Q9CZU3-1", "Q9Z1N5-1", "P08775-1", "Q569Z5-1", "Q61656-1", "Q810A7-1", "Q8CFI7-1", "O35286-1", "Q9D868-1", "Q61136-1", "Q6P4T2-1", "Q3TIX9-1" ], "evidence": [ { "id": "R-MMU-9770142", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9770142" } ] }, { "id": "R-MMU-9770145", "name": "Formation of the Spliceosomal Bact complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-MMU-8849149", "R-MMU-8867892", "R-MMU-9769562" ], "output_participant_list": [ "R-MMU-53517", "R-MMU-3246027", "R-MMU-71875", "R-MMU-71881", "R-MMU-9770239", "R-MMU-9770248", "R-MMU-9770255", "R-MMU-9770259" ], "enzyme_list": [ "Q99KP6-1", "D3Z0M9-1", "O70133-1", "Q9D6L8-1", "Q9CZU3-1", "Q9Z1N5-1", "P63017-1", "P08775-1", "Q569Z5-1", "Q61656-1", "Q810A7-1", "Q8CFI7-1", "Q8CFQ3-1", "O35286-1", "Q91VC3-1", "Q9D787-1", "Q9D868-1", "Q9QZH3-1", "Q9D0W5-1", "Q6P4T2-1", "G3X8X0-1" ], "evidence": [ { "id": "R-MMU-9770145", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9770145" } ] } ], "reaction_participants": [ { "participant_id": "R-MMU-3246027", "participant_name": "Tcerg1 [nucleoplasm]", "crossref": [ { "id": "Q8CGF7", "database": "UniProt", "url": "" }, { "id": "ENSMUSP00000134458", "database": "Ensembl", "url": "" }, { "id": "2RM0", "database": "PDB", "url": "" }, { "id": "2RLY", "database": "PDB", "url": "" }, { "id": "ENSMUST00000237602", "database": "Ensembl", "url": "" }, { "id": "2YSI", "database": "PDB", "url": "" }, { "id": "ENSMUSP00000158288", "database": "Ensembl", "url": "" }, { "id": "ENSMUSP00000025375", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000025375", "database": "Ensembl", "url": "" }, { "id": "ENSMUSG00000024498", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000173642", "database": "Ensembl", "url": "" }, { "id": "1926421", "database": "MGI", "url": "" }, { "id": "2JUP", "database": "PDB", "url": "" }, { "id": "Q8CGF7", "database": "PRO", "url": "" }, { "id": "XP_006526178.1", "database": "RefSeq", "url": "" }, { "id": "NP_001276455.1", "database": "RefSeq", "url": "" }, { "id": "1E0L", "database": "PDB", "url": "" }, { "id": "NP_001034563.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-MMU-4615999", "participant_name": "Sart1 [nucleoplasm]", "crossref": [ { "id": "Q9Z315", "database": "UniProt", "url": "" }, { "id": "1309453", "database": "MGI", "url": "" }, { "id": "ENSMUST00000044207", "database": "Ensembl", "url": "" }, { "id": "ENSMUSP00000047397", "database": "Ensembl", "url": "" }, { "id": "ENSMUSG00000039148", "database": "Ensembl", "url": "" }, { "id": "NP_058578.3", "database": "RefSeq", "url": "" }, { "id": "Q9Z315", "database": "PRO", "url": "" } ] }, { "participant_id": "R-MMU-53517", "participant_name": "DHX9 [nucleoplasm]", "crossref": [ { "id": "O70133", "database": "UniProt", "url": "" }, { "id": "NP_031868.2", "database": "RefSeq", "url": "" }, { "id": "108177", "database": "MGI", "url": "" }, { "id": "2RS7", "database": "PDB", "url": "" }, { "id": "1UIL", "database": "PDB", "url": "" }, { "id": "2RS6", "database": "PDB", "url": "" }, { "id": "1WHQ", "database": "PDB", "url": "" }, { "id": "O70133", "database": "PRO", "url": "" } ] }, { "participant_id": "R-MMU-6806778", "participant_name": "Snrnp27 [nucleoplasm]", "crossref": [ { "id": "Q8K194", "database": "UniProt", "url": "" }, { "id": "NP_079941.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUST00000113683", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000001186", "database": "Ensembl", "url": "" }, { "id": "ENSMUSG00000001158", "database": "Ensembl", "url": "" }, { "id": "ENSMUSP00000109313", "database": "Ensembl", "url": "" }, { "id": "1913868", "database": "MGI", "url": "" }, { "id": "ENSMUSP00000001186", "database": "Ensembl", "url": "" }, { "id": "Q8K194", "database": "PRO", "url": "" } ] }, { "participant_id": "R-MMU-6806793", "participant_name": "USP39 [nucleoplasm]", "crossref": [ { "id": "Q3TIX9", "database": "UniProt", "url": "" }, { "id": "Q3TIX9", "database": "PRO", "url": "" }, { "id": "107622", "database": "MGI", "url": "" }, { "id": "ENSMUSP00000064515", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000070345", "database": "Ensembl", "url": "" }, { "id": "ENSMUSG00000056305", "database": "Ensembl", "url": "" }, { "id": "NP_613058.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-MMU-71875", "participant_name": "Txnl4a [nucleoplasm]", "crossref": [ { "id": "P83877", "database": "UniProt", "url": "" }, { "id": "P83877", "database": "PRO", "url": "" }, { "id": "ENSMUST00000145963", "database": "Ensembl", "url": "" }, { "id": "ENSMUSG00000057130", "database": "Ensembl", "url": "" }, { "id": "ENSMUSP00000115320", "database": "Ensembl", "url": "" }, { "id": "NP_079575.1", "database": "RefSeq", "url": "" }, { "id": "1351613", "database": "MGI", "url": "" }, { "id": "XP_006526550.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-MMU-71879", "participant_name": "Ddx23 [nucleoplasm]", "crossref": [ { "id": "D3Z0M9", "database": "UniProt", "url": "" }, { "id": "XP_006521556.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUSP00000003450", "database": "Ensembl", "url": "" }, { "id": "ENSMUSG00000003360", "database": "Ensembl", "url": "" }, { "id": "1921601", "database": "MGI", "url": "" }, { "id": "ENSMUST00000003450", "database": "Ensembl", "url": "" }, { "id": "NP_001074450.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-MMU-71881", "participant_name": "Prpf6 [nucleoplasm]", "crossref": [ { "id": "Q91YR7", "database": "UniProt", "url": "" }, { "id": "Q91YR7", "database": "PRO", "url": "" }, { "id": "6QX9", "database": "PDB", "url": "" }, { "id": "ENSMUSP00000121340", "database": "Ensembl", "url": "" }, { "id": "NP_598462.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUSP00000002529", "database": "Ensembl", "url": "" }, { "id": "ENSMUSG00000002455", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000136481", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000002529", "database": "Ensembl", "url": "" }, { "id": "1922946", "database": "MGI", "url": "" } ] }, { "participant_id": "R-MMU-72049", "participant_name": "Rbm5 [nucleoplasm]", "crossref": [ { "id": "Q91YE7", "database": "UniProt", "url": "" }, { "id": "XP_006511933.1", "database": "RefSeq", "url": "" }, { "id": "NP_683732.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUSP00000138379", "database": "Ensembl", "url": "" }, { "id": "XP_011241223.1", "database": "RefSeq", "url": "" }, { "id": "XP_006511935.1", "database": "RefSeq", "url": "" }, { "id": "2CLV", "database": "PDB", "url": "" }, { "id": "Q91YE7", "database": "PRO", "url": "" }, { "id": "XP_006511934.1", "database": "RefSeq", "url": "" }, { "id": "2OL3", "database": "PDB", "url": "" }, { "id": "ENSMUSG00000032580", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000035199", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000182659", "database": "Ensembl", "url": "" }, { "id": "ENSMUSP00000035199", "database": "Ensembl", "url": "" }, { "id": "1933204", "database": "MGI", "url": "" } ] }, { "participant_id": "R-MMU-8849149", "participant_name": "EIF4A3 [nucleoplasm]", "crossref": [ { "id": "ENSMUSP00000026667", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000026667", "database": "Ensembl", "url": "" }, { "id": "1923731", "database": "MGI", "url": "" }, { "id": "Q91VC3", "database": "PRO", "url": "" }, { "id": "NP_619610.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUSG00000025580", "database": "Ensembl", "url": "" }, { "id": "Q91VC3", "database": "UniProt", "url": "" }, { "id": "3.6.4.13", "database": "IntEnz", "url": "" } ] }, { "participant_id": "R-MMU-8867887", "participant_name": "Wbp11 [nucleoplasm]", "crossref": [ { "id": "ENSMUST00000116514", "database": "Ensembl", "url": "" }, { "id": "XP_017177182.1", "database": "RefSeq", "url": "" }, { "id": "Q923D5", "database": "PRO", "url": "" }, { "id": "1891823", "database": "MGI", "url": "" }, { "id": "ENSMUSG00000030216", "database": "Ensembl", "url": "" }, { "id": "NP_068360.4", "database": "RefSeq", "url": "" }, { "id": "Q923D5", "database": "UniProt", "url": "" }, { "id": "ENSMUSP00000112213", "database": "Ensembl", "url": "" } ] }, { "participant_id": "R-MMU-8867889", "participant_name": "Pqbp1 [nucleoplasm]", "crossref": [ { "id": "Q91VJ5", "database": "PRO", "url": "" }, { "id": "ENSMUST00000115654", "database": "Ensembl", "url": "" }, { "id": "NP_001239457.1", "database": "RefSeq", "url": "" }, { "id": "NP_062351.2", "database": "RefSeq", "url": "" }, { "id": "XP_006527717.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUST00000115655", "database": "Ensembl", "url": "" }, { "id": "ENSMUSP00000033497", "database": "Ensembl", "url": "" }, { "id": "Q91VJ5", "database": "UniProt", "url": "" }, { "id": "1859638", "database": "MGI", "url": "" }, { "id": "ENSMUSP00000111319", "database": "Ensembl", "url": "" }, { "id": "ENSMUSG00000031157", "database": "Ensembl", "url": "" }, { "id": "ENSMUSP00000111318", "database": "Ensembl", "url": "" }, { "id": "NP_001239458.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUST00000033497", "database": "Ensembl", "url": "" } ] }, { "participant_id": "R-MMU-8867890", "participant_name": "Prpf40a [nucleoplasm]", "crossref": [ { "id": "Q9R1C7", "database": "UniProt", "url": "" }, { "id": "ENSMUSG00000061136", "database": "Ensembl", "url": "" }, { "id": "ENSMUSP00000159339", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000239398", "database": "Ensembl", "url": "" }, { "id": "1860512", "database": "MGI", "url": "" }, { "id": "NP_061255.1", "database": "RefSeq", "url": "" }, { "id": "Q9R1C7", "database": "PRO", "url": "" } ] }, { "participant_id": "R-MMU-8867892", "participant_name": "PPIL1 [nucleoplasm]", "crossref": [ { "id": "ENSMUSP00000024802", "database": "Ensembl", "url": "" }, { "id": "Q9D0W5", "database": "PRO", "url": "" }, { "id": "1916066", "database": "MGI", "url": "" }, { "id": "NP_081121.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUSG00000024007", "database": "Ensembl", "url": "" }, { "id": "Q9D0W5", "database": "UniProt", "url": "" }, { "id": "ENSMUST00000024802", "database": "Ensembl", "url": "" } ] }, { "participant_id": "R-MMU-8867895", "participant_name": "Wbp4 [nucleoplasm]", "crossref": [ { "id": "Q61048", "database": "PRO", "url": "" }, { "id": "ENSMUSP00000022601", "database": "Ensembl", "url": "" }, { "id": "109568", "database": "MGI", "url": "" }, { "id": "Q61048", "database": "UniProt", "url": "" }, { "id": "ENSMUSG00000022023", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000022601", "database": "Ensembl", "url": "" }, { "id": "NP_061235.2", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-MMU-8867897", "participant_name": "Prpf38a [nucleoplasm]", "crossref": [ { "id": "1916962", "database": "MGI", "url": "" }, { "id": "ENSMUSP00000078207", "database": "Ensembl", "url": "" }, { "id": "ENSMUSG00000063800", "database": "Ensembl", "url": "" }, { "id": "Q4FK66", "database": "PRO", "url": "" }, { "id": "NP_766285.2", "database": "RefSeq", "url": "" }, { "id": "Q4FK66", "database": "UniProt", "url": "" }, { "id": "ENSMUST00000079213", "database": "Ensembl", "url": "" } ] }, { "participant_id": "R-MMU-9769525", "participant_name": "PRPF4B [nucleoplasm]", "crossref": [ { "id": "Q61136", "database": "UniProt", "url": "" }, { "id": "109584", "database": "MGI", "url": "" }, { "id": "XP_017170914.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUST00000222509", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000077853", "database": "Ensembl", "url": "" }, { "id": "XP_017170918.1", "database": "RefSeq", "url": "" }, { "id": "NP_038858.2", "database": "RefSeq", "url": "" }, { "id": "XP_017170922.1", "database": "RefSeq", "url": "" }, { "id": "XP_017170917.1", "database": "RefSeq", "url": "" }, { "id": "XP_017170921.1", "database": "RefSeq", "url": "" }, { "id": "Q61136", "database": "PRO", "url": "" }, { "id": "XP_017170926.1", "database": "RefSeq", "url": "" }, { "id": "XP_017170925.1", "database": "RefSeq", "url": "" }, { "id": "2.7.11.1", "database": "IntEnz", "url": "" }, { "id": "XP_017170916.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUSG00000021413", "database": "Ensembl", "url": "" }, { "id": "XP_017170920.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUSP00000152654", "database": "Ensembl", "url": "" }, { "id": "XP_017170915.1", "database": "RefSeq", "url": "" }, { "id": "XP_017170924.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUSP00000077019", "database": "Ensembl", "url": "" }, { "id": "XP_017170919.1", "database": "RefSeq", "url": "" }, { "id": "XP_017170923.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-MMU-9769526", "participant_name": "Rbm42 [nucleoplasm]", "crossref": [ { "id": "Q91V81", "database": "UniProt", "url": "" }, { "id": "NP_598454.2", "database": "RefSeq", "url": "" }, { "id": "1915285", "database": "MGI", "url": "" }, { "id": "Q91V81", "database": "PRO", "url": "" }, { "id": "ENSMUSG00000036733", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000042726", "database": "Ensembl", "url": "" }, { "id": "ENSMUSP00000040005", "database": "Ensembl", "url": "" } ] }, { "participant_id": "R-MMU-9769562", "participant_name": "Ppil2 [nucleoplasm]", "crossref": [ { "id": "NP_001239374.1", "database": "RefSeq", "url": "" }, { "id": "Q9D787", "database": "UniProt", "url": "" }, { "id": "NP_001239373.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUSG00000022771", "database": "Ensembl", "url": "" }, { "id": "Q9D787", "database": "PRO", "url": "" }, { "id": "NP_659203.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUST00000023455", "database": "Ensembl", "url": "" }, { "id": "2447857", "database": "MGI", "url": "" }, { "id": "ENSMUSP00000023455", "database": "Ensembl", "url": "" }, { "id": "ENSMUSP00000131422", "database": "Ensembl", "url": "" }, { "id": "ENSMUSP00000155861", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000231712", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000164458", "database": "Ensembl", "url": "" } ] }, { "participant_id": "R-MMU-9770239", "participant_name": "Ik [nucleoplasm]", "crossref": [ { "id": "Q9Z1M8", "database": "UniProt", "url": "" }, { "id": "1345142", "database": "MGI", "url": "" }, { "id": "NP_036009.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUSP00000007042", "database": "Ensembl", "url": "" }, { "id": "ENSMUSG00000024474", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000007042", "database": "Ensembl", "url": "" }, { "id": "Q9Z1M8", "database": "PRO", "url": "" } ] }, { "participant_id": "R-MMU-9770248", "participant_name": "Zmat2 [nucleoplasm]", "crossref": [ { "id": "Q9CPW7", "database": "UniProt", "url": "" }, { "id": "ENSMUSP00000001419", "database": "Ensembl", "url": "" }, { "id": "ENSMUSG00000001383", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000001419", "database": "Ensembl", "url": "" }, { "id": "Q9CPW7", "database": "PRO", "url": "" }, { "id": "NP_079870.1", "database": "RefSeq", "url": "" }, { "id": "1913742", "database": "MGI", "url": "" } ] }, { "participant_id": "R-MMU-9770250", "participant_name": "Rbm25 [nucleoplasm]", "crossref": [ { "id": "B2RY56", "database": "UniProt", "url": "" }, { "id": "NP_081625.3", "database": "RefSeq", "url": "" }, { "id": "XP_006516232.1", "database": "RefSeq", "url": "" }, { "id": "XP_006516231.1", "database": "RefSeq", "url": "" }, { "id": "XP_006516230.1", "database": "RefSeq", "url": "" }, { "id": "B2RY56", "database": "PRO", "url": "" }, { "id": "ENSMUSP00000048470", "database": "Ensembl", "url": "" }, { "id": "ENSMUSG00000010608", "database": "Ensembl", "url": "" }, { "id": "1914289", "database": "MGI", "url": "" }, { "id": "ENSMUST00000048155", "database": "Ensembl", "url": "" }, { "id": "XP_017170651.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-MMU-9770254", "participant_name": "Rbm39 [nucleoplasm]", "crossref": [ { "id": "Q8VH51", "database": "UniProt", "url": "" }, { "id": "ENSMUST00000029149", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000109587", "database": "Ensembl", "url": "" }, { "id": "ENSMUSG00000027620", "database": "Ensembl", "url": "" }, { "id": "5CXT", "database": "PDB", "url": "" }, { "id": "XP_011237628.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUSP00000105216", "database": "Ensembl", "url": "" }, { "id": "Q8VH51", "database": "PRO", "url": "" }, { "id": "XP_017171497.1", "database": "RefSeq", "url": "" }, { "id": "4RU2", "database": "PDB", "url": "" }, { "id": "NP_573505.2", "database": "RefSeq", "url": "" }, { "id": "ENSMUSP00000119298", "database": "Ensembl", "url": "" }, { "id": "4J5O", "database": "PDB", "url": "" }, { "id": "ENSMUST00000146297", "database": "Ensembl", "url": "" }, { "id": "2157953", "database": "MGI", "url": "" }, { "id": "ENSMUSP00000029149", "database": "Ensembl", "url": "" }, { "id": "XP_017171494.1", "database": "RefSeq", "url": "" }, { "id": "NP_001278044.1", "database": "RefSeq", "url": "" }, { "id": "3S6E", "database": "PDB", "url": "" }, { "id": "XP_017171487.1", "database": "RefSeq", "url": "" }, { "id": "XP_017171483.1", "database": "RefSeq", "url": "" }, { "id": "NP_001278043.1", "database": "RefSeq", "url": "" }, { "id": "2LQ5", "database": "PDB", "url": "" }, { "id": "XP_011237629.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-MMU-9770255", "participant_name": "Ubl5 [nucleoplasm]", "crossref": [ { "id": "Q9EPV8", "database": "UniProt", "url": "" }, { "id": "Q9EPV8", "database": "PRO", "url": "" }, { "id": "1913427", "database": "MGI", "url": "" }, { "id": "1UH6", "database": "PDB", "url": "" }, { "id": "ENSMUSP00000125364", "database": "Ensembl", "url": "" }, { "id": "XP_006510607.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUSP00000124672", "database": "Ensembl", "url": "" }, { "id": "NP_079677.1", "database": "RefSeq", "url": "" }, { "id": "ENSMUST00000160682", "database": "Ensembl", "url": "" }, { "id": "ENSMUSP00000124812", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000129414", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000162303", "database": "Ensembl", "url": "" }, { "id": "ENSMUSG00000084786", "database": "Ensembl", "url": "" }, { "id": "ENSMUSP00000123971", "database": "Ensembl", "url": "" }, { "id": "ENSMUST00000160124", "database": "Ensembl", "url": "" } ] }, { "participant_id": "R-MMU-9770259", "participant_name": "Smu1 [nucleoplasm]", "crossref": [ { "id": "Q3UKJ7", "database": "UniProt", "url": "" }, { "id": "ENSMUST00000030117", "database": "Ensembl", "url": "" }, { "id": "ENSMUSP00000030117", "database": "Ensembl", "url": "" }, { "id": "NP_067510.3", "database": "RefSeq", "url": "" }, { "id": "1915546", "database": "MGI", "url": "" }, { "id": "Q3UKJ7", "database": "PRO", "url": "" }, { "id": "ENSMUSG00000028409", "database": "Ensembl", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "D3Z0M9", "gene_name": "Ddx23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "D3Z0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "D3Z0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/D3Z0M9" } ] } ] }, { "uniprot_ac": "G3X8X0", "gene_name": "Dhx16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "G3X8X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3X8X0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3X8X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/G3X8X0" } ] } ] }, { "uniprot_ac": "O35286", "gene_name": "Dhx15", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O35286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35286" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O35286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35286" } ] } ] }, { "uniprot_ac": "O70133", "gene_name": "Dhx9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "O70133", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70133" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O70133", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70133" } ] } ] }, { "uniprot_ac": "P08775", "gene_name": "Polr2a", "activity": [ { "ec_number": "2.7.7.6", "activity": "a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1).", "evidence": [ { "id": "P08775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08775" } ] }, { "ec_number": "2.7.7.6", "activity": "", "evidence": [ { "id": "P08775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08775" } ] } ] }, { "uniprot_ac": "P63017", "gene_name": "Hspa8", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "P63017", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63017" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P63017", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P63017" } ] } ] }, { "uniprot_ac": "Q3TIX9", "gene_name": "Usp39", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "Q3TIX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3TIX9" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "Q3TIX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3TIX9" } ] } ] }, { "uniprot_ac": "Q569Z5", "gene_name": "Ddx46", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "Q569Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q569Z5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q569Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q569Z5" } ] } ] }, { "uniprot_ac": "Q61136", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "Q61136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61136" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q61136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61136" } ] } ] }, { "uniprot_ac": "Q61656", "gene_name": "Ddx5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "Q61656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61656" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q61656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61656" } ] } ] }, { "uniprot_ac": "Q6P4T2", "gene_name": "Snrnp200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "Q6P4T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P4T2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q6P4T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6P4T2" } ] } ] }, { "uniprot_ac": "Q810A7", "gene_name": "Ddx42", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "Q810A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810A7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q810A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q810A7" } ] } ] }, { "uniprot_ac": "Q8CFI7", "gene_name": "Polr2b", "activity": [ { "ec_number": "2.7.7.6", "activity": "a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1).", "evidence": [ { "id": "Q8CFI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CFI7" } ] }, { "ec_number": "2.7.7.6", "activity": "", "evidence": [ { "id": "Q8CFI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CFI7" } ] } ] }, { "uniprot_ac": "Q8CFQ3", "gene_name": "Aqr", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "Q8CFQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CFQ3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q8CFQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q8CFQ3" } ] } ] }, { "uniprot_ac": "Q91VC3", "gene_name": "Eif4a3", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "Q91VC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91VC3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q91VC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91VC3" } ] } ] }, { "uniprot_ac": "Q99KP6", "gene_name": "Prpf19", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q99KP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99KP6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q99KP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q99KP6" } ] } ] }, { "uniprot_ac": "Q9CZU3", "gene_name": "Mtrex", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "Q9CZU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CZU3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q9CZU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9CZU3" } ] } ] }, { "uniprot_ac": "Q9D0W5", "gene_name": "Ppil1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q9D0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D0W5" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q9D0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D0W5" } ] } ] }, { "uniprot_ac": "Q9D6L8", "gene_name": "Ppil3", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q9D6L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D6L8" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q9D6L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D6L8" } ] } ] }, { "uniprot_ac": "Q9D787", "gene_name": "Ppil2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9D787", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D787" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9D787", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D787" } ] } ] }, { "uniprot_ac": "Q9D868", "gene_name": "Ppih", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q9D868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D868" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q9D868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9D868" } ] } ] }, { "uniprot_ac": "Q9QZH3", "gene_name": "Ppie", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q9QZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QZH3" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q9QZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QZH3" } ] } ] }, { "uniprot_ac": "Q9Z1N5", "gene_name": "Ddx39b", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + H(+) + phosphate.", "evidence": [ { "id": "Q9Z1N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1N5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q9Z1N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9Z1N5" } ] } ] } ], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }