{
    "uniprot_canonical_ac": "B7YZT2-1",
    "uniprot_ac": "B7YZT2",
    "uniprot_id": "FIS1_DROME",
    "mass": {
        "chemical_mass": 17771.0,
        "monoisotopic_mass": 17771.0
    },
    "refseq": {
        "ac": "NP_001137607",
        "name": "Fission, mitochondrial 1, isoform C",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137607"
    },
    "gene_names": [
        {
            "name": "Fis1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/B7YZT2",
            "id": "B7YZT2"
        },
        {
            "name": "BcDNA:RE29957; bs15a08.y1; CG17510; dFis1; Dmel\\CG17510; fis1; FIS1; NEST:bs15a08",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137607",
            "id": "NP_001137607"
        },
        {
            "name": "CG17510",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/B7YZT2",
            "id": "B7YZT2"
        },
        {
            "name": "Fis1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137607",
            "id": "NP_001137607"
        }
    ],
    "protein_names": [
        {
            "name": "Mitochondrial fission 1 protein",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "B7YZT2"
        },
        {
            "name": "CG17510-PC; Fis1-PC",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137607",
            "id": "NP_001137607"
        },
        {
            "name": "Fission, mitochondrial 1, isoform C",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137607",
            "id": "NP_001137607"
        }
    ],
    "function": [
        {
            "annotation": "Involved in the fragmentation of the mitochondrial network and its perinuclear clustering (PubMed:18443288, PubMed:20194754). Functions downstream of Pink1 and upstream of Drp1 to regulate mitochondrial fission (PubMed:18443288).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "B7YZT2",
                    "url": "https://www.uniprot.org/uniprot/B7YZT2#function"
                },
                {
                    "database": "PubMed",
                    "id": "20194754",
                    "url": "https://glygen.org/publication/PubMed/20194754"
                },
                {
                    "database": "PubMed",
                    "id": "18443288",
                    "url": "https://glygen.org/publication/PubMed/18443288"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:10652",
            "recommended_name": {
                "id": "DOID:10652",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:10652",
                "name": "Alzheimer's disease",
                "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid."
            },
            "synonyms": [
                {
                    "id": "DOID:10652",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10652",
                    "name": "Alzheimer disease",
                    "description": ""
                },
                {
                    "id": "DOID:10652",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10652",
                    "name": "Alzheimers dementia",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "10652",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:10652"
                }
            ]
        },
        {
            "disease_id": "DOID:13711",
            "recommended_name": {
                "id": "DOID:13711",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:13711",
                "name": "dental fluorosis",
                "description": "A tooth disease characterized by enamel discoloration resulting from excess fluoride ingestion during tooth formation."
            },
            "synonyms": [
                {
                    "id": "DOID:13711",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:13711",
                    "name": "Intrinsic enamel discolouration of fluorosis",
                    "description": ""
                },
                {
                    "id": "DOID:13711",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:13711",
                    "name": "Mottled teeth",
                    "description": ""
                },
                {
                    "id": "DOID:13711",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:13711",
                    "name": "Mottling of enamel",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "13711",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:13711"
                }
            ]
        },
        {
            "disease_id": "DOID:3021",
            "recommended_name": {
                "id": "DOID:3021",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:3021",
                "name": "acute kidney failure",
                "description": ""
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "3021",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:3021"
                }
            ]
        },
        {
            "disease_id": "DOID:4483",
            "recommended_name": {
                "id": "DOID:4483",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:4483",
                "name": "rhinitis",
                "description": "A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "4483",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:4483"
                }
            ]
        },
        {
            "disease_id": "DOID:5844",
            "recommended_name": {
                "id": "DOID:5844",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:5844",
                "name": "myocardial infarction",
                "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia."
            },
            "synonyms": [
                {
                    "id": "DOID:5844",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5844",
                    "name": "Myocardial infarct",
                    "description": ""
                },
                {
                    "id": "DOID:5844",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5844",
                    "name": "heart attack",
                    "description": ""
                },
                {
                    "id": "MONDO:0012058",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012058",
                    "name": "myocardial infarction, susceptibility to, 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012058",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012058",
                    "name": "myocardial infarction, susceptibility to, 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012058",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012058",
                    "name": "myocardial infarction, susceptibility to, type 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012058",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012058",
                    "name": "Mci2",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "5844",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:5844"
                }
            ]
        },
        {
            "disease_id": "DOID:784",
            "recommended_name": {
                "id": "DOID:784",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:784",
                "name": "chronic kidney disease",
                "description": "A kidney failure that is characterized by the gradual loss of kidney function."
            },
            "synonyms": [
                {
                    "id": "DOID:784",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:784",
                    "name": "CKD",
                    "description": ""
                },
                {
                    "id": "DOID:784",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:784",
                    "name": "CRF",
                    "description": ""
                },
                {
                    "id": "DOID:784",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:784",
                    "name": "chronic kidney failure",
                    "description": ""
                },
                {
                    "id": "DOID:784",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:784",
                    "name": "chronic renal disease",
                    "description": ""
                },
                {
                    "id": "DOID:784",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:784",
                    "name": "chronic renal failure syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:784",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:784",
                    "name": "renal failure - chronic",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "784",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:784"
                }
            ]
        },
        {
            "disease_id": "DOID:9452",
            "recommended_name": {
                "id": "DOID:9452",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:9452",
                "name": "steatotic liver disease",
                "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes."
            },
            "synonyms": [
                {
                    "id": "DOID:9452",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9452",
                    "name": "SLD",
                    "description": ""
                },
                {
                    "id": "DOID:9452",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9452",
                    "name": "fatty liver disease",
                    "description": ""
                },
                {
                    "id": "DOID:9452",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9452",
                    "name": "Fatty change of liver",
                    "description": ""
                },
                {
                    "id": "DOID:9452",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9452",
                    "name": "Steatosis of liver",
                    "description": ""
                },
                {
                    "id": "DOID:9452",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9452",
                    "name": "alcoholic fatty liver",
                    "description": ""
                },
                {
                    "id": "DOID:9452",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9452",
                    "name": "hepatic lipidosis",
                    "description": ""
                },
                {
                    "id": "DOID:9452",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9452",
                    "name": "hepatic steatosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009220",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009220",
                    "name": "visceral steatosis, congenital",
                    "description": ""
                },
                {
                    "id": "MONDO:0009220",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009220",
                    "name": "visceral steatosis, congenital",
                    "description": ""
                },
                {
                    "id": "MONDO:0009220",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009220",
                    "name": "White liver disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0009220",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009220",
                    "name": "fatal neonatal hepatic steatosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009220",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009220",
                    "name": "fatty liver disease, congenital",
                    "description": ""
                },
                {
                    "id": "MONDO:0009220",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009220",
                    "name": "fatty metamorphosis of viscera",
                    "description": ""
                },
                {
                    "id": "MONDO:0009220",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009220",
                    "name": "steatosis of liver",
                    "description": ""
                },
                {
                    "id": "MONDO:0009220",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009220",
                    "name": "visceral steatosis",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "9452",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:9452"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Drosophila melanogaster",
            "taxid": 7227,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "B7YZT2",
                    "url": "https://www.uniprot.org/uniprot/B7YZT2"
                }
            ],
            "common_name": "Fruit fly"
        }
    ],
    "gene": [
        {
            "name": "Fis1",
            "url": "https://www.uniprot.org/uniprot/B7YZT2",
            "locus": {
                "chromosome": "2R",
                "start_pos": 5603587,
                "end_pos": 5604834,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "FBgn0039969",
                        "url": "https://www.ensembl.org/id/FBgn0039969"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "FBgn0039969",
            "url": "https://bgee.org/?page=gene&gene_id=FBgn0039969",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd12212",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12212",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "FBgn0039969",
            "url": "https://flybase.org/reports/FBgn0039969",
            "database": "FlyBase",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "49892",
            "url": "https://www.ncbi.nlm.nih.gov/gene/49892",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "B7YZT2",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:B7YZT2*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR011990",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR016543",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR016543",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR028058",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR028058",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR028061",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR028061",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR033745",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR033745",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dme:Dmel_CG17510",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG17510",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "ERQINKR",
            "url": "https://omabrowser.org/oma/group/ERQINKR/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "2997323at2759",
            "url": "http://www.orthodb.org/?query=2997323at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR13247",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13247",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR13247:SF0",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13247:SF0",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF14852",
            "url": "http://pfam.xfam.org/family/PF14852",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF14853",
            "url": "http://pfam.xfam.org/family/PF14853",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_B7YZT2",
            "url": "http://purl.obolibrary.org/obo/PR_B7YZT2",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-DME-9603798",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9603798",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001137607",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137607",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "B7YZT2",
            "url": "https://www.uniprot.org/uniprot/B7YZT2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "B7YZT2-1",
            "url": "https://www.uniprot.org/uniprot/B7YZT2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "B7YZT2-2",
            "url": "https://www.uniprot.org/uniprot/B7YZT2-2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "B7YZT2-3",
            "url": "https://www.uniprot.org/uniprot/B7YZT2-3",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "B7YZT2-4",
            "url": "https://www.uniprot.org/uniprot/B7YZT2-4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MEDLLNEVVPQEDLERFEKKYHHELELDGEVTTDTKFEYAFCLVRSRYTNDVRKGIMILEELARTHPDGRRDYIYYLAFGNARIKEYTSGLKYCRAFLDIESNDQVRSLEEYIKKEIDKEVAKGMVVAGGAALVLGGILGLGIAMARNKQKREK",
        "length": 154,
        "header": "sp|B7YZT2-1|FIS1_DROME Isoform 1 of Mitochondrial fission 1 protein  OS=Drosophila melanogaster OX=7227 GN=Fis1 PE=2 SV=1 CANONICAL=B7YZT2-1"
    },
    "isoforms": [
        {
            "isoform_ac": "B7YZT2-1",
            "url": "",
            "sequence": {
                "sequence": "MEDLLNEVVPQEDLERFEKKYHHELELDGEVTTDTKFEYAFCLVRSRYTNDVRKGIMILEELARTHPDGRRDYIYYLAFGNARIKEYTSGLKYCRAFLDIESNDQVRSLEEYIKKEIDKEVAKGMVVAGGAALVLGGILGLGIAMARNKQKREK",
                "length": 154,
                "header": "sp|B7YZT2-1|FIS1_DROME Isoform 1 of Mitochondrial fission 1 protein  OS=Drosophila melanogaster OX=7227 GN=Fis1 PE=2 SV=1 CANONICAL=B7YZT2-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 5604754,
                "end_pos": 5603743,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0273208",
                        "url": "https://www.ensembl.org/id/FBtr0273208"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0271716",
                        "url": "https://www.ensembl.org/id/FBpp0271716"
                    }
                ]
            }
        },
        {
            "isoform_ac": "B7YZT2-2",
            "url": "",
            "sequence": {
                "sequence": "MEDLLNEVVPQEDLERFEKKYHHELELDGEVTTDTKFEYAFCLVRSRYTNDVRKGIMILEELARTHPDGRRDYIYYLAFGNARIKEYTSGLKYCRAFLDIESNDQVRSLEEYIKKEIDKEVAKGMVVAGGAALVLGGILGLGIAMARK",
                "length": 148,
                "header": "sp|B7YZT2-2|FIS1_DROME Isoform 2 of Mitochondrial fission 1 protein  OS=Drosophila melanogaster OX=7227 GN=Fis1 PE=2 SV=1 CANONICAL=B7YZT2-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 5604754,
                "end_pos": 5603899,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0273210",
                        "url": "https://www.ensembl.org/id/FBtr0273210"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0271718",
                        "url": "https://www.ensembl.org/id/FBpp0271718"
                    }
                ]
            }
        },
        {
            "isoform_ac": "B7YZT2-3",
            "url": "",
            "sequence": {
                "sequence": "MILEELARTHPDGRRDYIYYLAFGNARIKEYTSGLKYCRAFLDIESNDQVRSLEEYIKKEIDKEVAKGMVVAGGAALVLGGILGLGIAMARK",
                "length": 92,
                "header": "sp|B7YZT2-3|FIS1_DROME Isoform 3 of Mitochondrial fission 1 protein  OS=Drosophila melanogaster OX=7227 GN=Fis1 PE=2 SV=1 CANONICAL=B7YZT2-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 5604405,
                "end_pos": 5603899,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0273211",
                        "url": "https://www.ensembl.org/id/FBtr0273211"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0271719",
                        "url": "https://www.ensembl.org/id/FBpp0271719"
                    }
                ]
            }
        },
        {
            "isoform_ac": "B7YZT2-4",
            "url": "",
            "sequence": {
                "sequence": "MILEELARTHPDGRRDYIYYLAFGNARIKEYTSGLKYCRAFLDIESNDQVRSLEEYIKKEIDKEVAKGMVVAGGAALVLGGILGLGIAMARNKQKREK",
                "length": 98,
                "header": "sp|B7YZT2-4|FIS1_DROME Isoform 4 of Mitochondrial fission 1 protein  OS=Drosophila melanogaster OX=7227 GN=Fis1 PE=2 SV=1 CANONICAL=B7YZT2-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 5604405,
                "end_pos": 5603743,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0345012",
                        "url": "https://www.ensembl.org/id/FBtr0345012"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0311263",
                        "url": "https://www.ensembl.org/id/FBpp0311263"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "The genome sequence of Drosophila melanogaster.",
            "journal": "Science",
            "date": "2000",
            "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "B7YZT2",
                    "url": "https://www.uniprot.org/uniprot/B7YZT2"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "10731132",
                    "url": "https://glygen.org/publication/PubMed/10731132"
                }
            ]
        },
        {
            "title": "A Drosophila full-length cDNA resource.",
            "journal": "Genome Biol.",
            "date": "2002",
            "authors": "Stapleton M, Carlson J, Brokstein P, Yu C, Champe M, George R, Guarin H, Kronmiller B, Pacleb J, Park S, Wan K, Rubin GM, Celniker SE",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "B7YZT2",
                    "url": "https://www.uniprot.org/uniprot/B7YZT2"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12537569",
                    "url": "https://glygen.org/publication/PubMed/12537569"
                }
            ]
        },
        {
            "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.",
            "journal": "Genome Biol.",
            "date": "2002",
            "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "B7YZT2",
                    "url": "https://www.uniprot.org/uniprot/B7YZT2"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12537572",
                    "url": "https://glygen.org/publication/PubMed/12537572"
                }
            ]
        },
        {
            "title": "Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery.",
            "journal": "Proc. Natl. Acad. Sci. U.S.A.",
            "date": "2008",
            "authors": "Lu B., Yang L., Yang Y., Vogel H., Ouyang Y., Beal M.F., McQuibban A.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "B7YZT2",
                    "url": "https://www.uniprot.org/uniprot/B7YZT2"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "18443288",
                    "url": "https://glygen.org/publication/PubMed/18443288"
                }
            ]
        },
        {
            "title": "Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin.",
            "journal": "Proc. Natl. Acad. Sci. U.S.A.",
            "date": "2010",
            "authors": "Ziviani E, Tao RN, Whitworth AJ",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "B7YZT2",
                    "url": "https://www.uniprot.org/uniprot/B7YZT2"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "20194754",
                    "url": "https://glygen.org/publication/PubMed/20194754"
                }
            ]
        }
    ],
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        {
            "id": "dme:Dmel_CG17510",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG17510",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-DME-9603798",
            "name": "Class I peroxisomal membrane protein import",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9603798",
            "resource": "Reactome",
            "description": "Class I peroxisomal membrane protein import"
        }
    ],
    "orthologs": [],
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            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "mitochondrial outer membrane",
                        "id": "GO:0005741",
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                    },
                    {
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                ]
            },
            {
                "name": "Biological Process",
                "total": 6,
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                    },
                    {
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                        ],
                        "pmid": ""
                    },
                    {
                        "name": "autophagy of mitochondrion",
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                                "id": "B7YZT2",
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                    {
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                    }
                ]
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}
