{ "uniprot_canonical_ac": "B5DF37-1", "uniprot_ac": "B5DF37", "uniprot_id": "B5DF37_RAT", "mass": { "chemical_mass": 68038.0, "monoisotopic_mass": 68038.0 }, "refseq": { "ac": "NP_001101045", "name": "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101045" }, "gene_names": [ { "name": "Taf6l", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/B5DF37", "id": "B5DF37" }, { "name": "Taf6l", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101045", "id": "NP_001101045" } ], "protein_names": [ { "name": "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101045", "id": "NP_001101045" }, { "name": "TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101045", "id": "NP_001101045" }, { "name": "TATA-box binding protein associated factor 6 like", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "B5DF37" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "B5DF37", "url": "https://www.uniprot.org/uniprot/B5DF37" } ], "common_name": "Rat" } ], "gene": [ { "name": "Taf6l", "url": "https://www.uniprot.org/uniprot/B5DF37", "locus": { "chromosome": "1", "start_pos": 205672149, "end_pos": 205684655, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000019419", "url": "https://www.ensembl.org/id/ENSRNOG00000019419" } ] } } ], "crossref": [ { "id": "ENSRNOG00000019419", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000019419", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08050", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08050", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "309194", "url": "https://www.ncbi.nlm.nih.gov/gene/309194", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:309194", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:309194", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YYQHVTR", "url": "https://omabrowser.org/oma/group/YYQHVTR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "3014558at2759", "url": "http://www.orthodb.org/?query=3014558at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10221", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10221", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10221:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10221:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02969", "url": "http://pfam.xfam.org/family/PF02969", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF07571", "url": "http://pfam.xfam.org/family/PF07571", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001101045", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101045", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1310123", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1310123", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A8I6ARN5", "url": "https://www.uniprot.org/uniprot/A0A8I6ARN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6ARN5-1", "url": "https://www.uniprot.org/uniprot/A0A8I6ARN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B5DF37", "url": "https://www.uniprot.org/uniprot/B5DF37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B5DF37-1", "url": "https://www.uniprot.org/uniprot/B5DF37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHSSTGAMSEREERRFVEIPRESVRLMAESTGLELSDEVAALLAEDVCYRLREATQNSSQFMKHTKRRKLTVEDFNRALRWSSVEAVCGYGSQEVLPLRPAREGELYFPEDREVNLVELALATNIPKGCAETAVRVHVSYLDGKGNLAPQGSVPSAVSSLTDDLLKYYQQVTRAVLGDDPQLMKVALQDLQTNSKIAALLPYFVYVVSGVKSVSHDLEQLHRLLQVARSLIRNPHLCLGPYVRSLVGSVLYCVLEPLAASINPLNDHWTLRDGAALLLSHIFWTHGDLVSGLYQQILLSLQKVLTDPVRPLCSHYGAVVGLHALGWKAVERVLYPHLPTYWTNLQAVLDDYSVSNAQVKADGHKVYGAILVAVERLLKMKAQAAEPNRGGLGGRGYRPAEDLPWDSLLLQESPPGGGSEPGFGSGLLLPSGVAGSEDPSSLTLADIYRELYSFFGDSLATRFGTGQPAPTAPRPPGDKKEPATTPDSVRKMPQLTASAVVSPQGDESPCGGTLAAANATSESRPLPRVHRARGAPRQQGPGAGTRDVFQKSRFAPRGAPHFRFIIAGRQAGRRCRGRLFQTAFPAPYGPSPASRYVQKLPMIGRTGRPARRWALSDYSLYLPL", "length": 623, "header": "tr|B5DF37-1|B5DF37_RAT Isoform 1 of TATA-box binding protein associated factor 6 like OS=Rattus norvegicus OX=10116 GN=Taf6l PE=3 SV=1 CANONICAL=B5DF37-1" }, "isoforms": [ { "isoform_ac": "A0A8I6ARN5-1", "url": "", "sequence": { "sequence": "MHSSTGAMSEREERRFVEIPRESVRLMAESTGLELSDEVAALLAEDVCYRLREATQNSSQFMKHTKRRKLTVEDFNRALRWSSVEAVCGYGSQEVLPLRPAREGELYFPEDREVNLVELALATNIPKGCAETAVRVHVSYLDGKGNLAPQGSVPSAVSSLTDDLLKYYQQVTRAVLGDDPQLMKVKSVSHDLEQLHRLLQVARSLIRNPHLCLGPYVRSLVGSVLYCVLEPLAASINPLNDHWTLRDGAALLLSHIFWTHGDLVSGLYQQILLSLQKVLTDPVRPLCSHYGAVVGLHALGWKAVERVLYPHLPTYWTNLQAVLDDYSVSNAQVKADGHKVYGAILVAVERLLKMKAQAAEPNRGGLGGRGYRPAEDLPWDSLLLQESPPGGGSEPGFGSGLLLPSGVAGSEDPSSLTLADIYRELYSFFGDSLATRFGTGQPAPTAPRPPGDKKEPATTPDSVRKMPQLTASAVVSPQGDESPCGGTLAAANATSESRPLPRVHRARGAPRQQGPGAGTRDVFQKSRFAPRGAPHFRFIIAGRQAGRRCRGRLFQTAFPAPYGPSPASRYVQKLPMIGRTGRPARRWALSDYSLYLPL", "length": 598, "header": "tr|A0A8I6ARN5-1|B5DF37_RAT Computationally mapped isoform of TATA-box binding protein associated factor 6 like OS=Rattus norvegicus OX=10116 GN=Taf6l PE=3 SV=1 CANONICAL=B5DF37-1" }, "locus": { "chromosome": "1", "start_pos": 205683372, "end_pos": 205672187, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000101052.1", "url": "https://www.ensembl.org/id/ENSRNOT00000101052.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000094467.1", "url": "https://www.ensembl.org/id/ENSRNOP00000094467.1" } ] } }, { "isoform_ac": "B5DF37-1", "url": "", "sequence": { "sequence": "MHSSTGAMSEREERRFVEIPRESVRLMAESTGLELSDEVAALLAEDVCYRLREATQNSSQFMKHTKRRKLTVEDFNRALRWSSVEAVCGYGSQEVLPLRPAREGELYFPEDREVNLVELALATNIPKGCAETAVRVHVSYLDGKGNLAPQGSVPSAVSSLTDDLLKYYQQVTRAVLGDDPQLMKVALQDLQTNSKIAALLPYFVYVVSGVKSVSHDLEQLHRLLQVARSLIRNPHLCLGPYVRSLVGSVLYCVLEPLAASINPLNDHWTLRDGAALLLSHIFWTHGDLVSGLYQQILLSLQKVLTDPVRPLCSHYGAVVGLHALGWKAVERVLYPHLPTYWTNLQAVLDDYSVSNAQVKADGHKVYGAILVAVERLLKMKAQAAEPNRGGLGGRGYRPAEDLPWDSLLLQESPPGGGSEPGFGSGLLLPSGVAGSEDPSSLTLADIYRELYSFFGDSLATRFGTGQPAPTAPRPPGDKKEPATTPDSVRKMPQLTASAVVSPQGDESPCGGTLAAANATSESRPLPRVHRARGAPRQQGPGAGTRDVFQKSRFAPRGAPHFRFIIAGRQAGRRCRGRLFQTAFPAPYGPSPASRYVQKLPMIGRTGRPARRWALSDYSLYLPL", "length": 623, "header": "tr|B5DF37-1|B5DF37_RAT Isoform 1 of TATA-box binding protein associated factor 6 like OS=Rattus norvegicus OX=10116 GN=Taf6l PE=3 SV=1 CANONICAL=B5DF37-1" }, "locus": { "chromosome": "1", "start_pos": 205683372, "end_pos": 205672187, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000026284.8", "url": "https://www.ensembl.org/id/ENSRNOT00000026284.8" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000026284.6", "url": "https://www.ensembl.org/id/ENSRNOP00000026284.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "rno:309194", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:309194", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8R2K4-1", "protein_name": "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "gene_name": "Taf6l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEREERRFVEIPRESVRLMAESTGLELSDEVAALLAEDVCYRLREATQNSSQFMKHTKRRKLTVEDFNRALRWSSVEAVCGYGSQEALPLRPAREGDLYFPEDREVSLVELALATNIPKGCAETAVRVHVSYLDGKGNLAPQGSVPSAVSSLTDDLLKYYQQVTRAVLGDDPQLMKVALQDLQTNSKIAALLPYFVYVVSGVKSVSHDLEQLHRLLQVARSLIRNPHLCLGPYVRSLVGSVLYCVLEPLAASINPLNDHWTLRDGAALLLSHIFWTHGDLVSGLYQQILLSLQKVLTDPVRPLCSHYGAVVGLHALGWKAVERVLYPHLPTYWTNLQAVLDDYSVSNAQVKADGHKVYGAILVAVERLLKMKAQAAEPNRGGLGGRGYRPAEDLPWDSLLLQESPPGGSSETGFGSGLPPPSGVAGPEDPSSLTLADIYRELYSFFGDSLATRFGTGQPAPTAPRPPGDKKEPAAAPDSVRKMPQLTASAVVSPQGDESPCGGTLATATAASESRPLPRVHRARGAPRQQGPGAGTRDVFQKSRFAPRGAPHFRFIIAGRQAGRRCRGRLFQTAFPAPYGPSPASRYVQKLPMIGRTGRPARRWALSDYSLYLPL", "length": 616 }, "evidence": [ { "id": "45231683", "url": "http://www.informatics.jax.org/homology/45231683", "database": "MGI" } ], "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y6J9-1", "protein_name": "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "gene_name": "TAF6L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEREERRFVEIPRESVRLMAESTGLELSDEVAALLAEDVCYRLREATQNSSQFMKHTKRRKLTVEDFNRALRWSSVEAVCGYGSQEALPMRPAREGELYFPEDREVNLVELALATNIPKGCAETAVRVHVSYLDGKGNLAPQGSVPSAVSSLTDDLLKYYHQVTRAVLGDDPQLMKVALQDLQTNSKIGALLPYFVYVVSGVKSVSHDLEQLHRLLQVARSLFRNPHLCLGPYVRCLVGSVLYCVLEPLAASINPLNDHWTLRDGAALLLSHIFWTHGDLVSGLYQHILLSLQKILADPVRPLCCHYGAVVGLHALGWKAVERVLYPHLSTYWTNLQAVLDDYSVSNAQVKADGHKVYGAILVAVERLLKMKAQAAEPNRGGPGGRGCRRLDDLPWDSLLFQESSSGGGAEPSFGSGLPLPPGGAGPEDPSLSVTLADIYRELYAFFGDSLATRFGTGQPAPTAPRPPGDKKEPAAAPDSVRKMPQLTASAIVSPHGDESPRGSGGGGPASASGPAASESRPLPRVHRARGAPRQQGPGTGTRDVFQKSRFAPRGAPHFRFIIAGRQAGRRCRGRLFQTAFPAPYGPSPASRYVQKLPMIGRTSRPARRWALSDYSLYLPL", "length": 622 }, "evidence": [ { "id": "45231683", "url": "http://www.informatics.jax.org/homology/45231683", "database": "MGI" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "B5DF37", "url": "https://www.uniprot.org/uniprot/B5DF37" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "B5DF37", "url": "https://www.uniprot.org/uniprot/B5DF37" } ], "pmid": "" }, { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "B5DF37", "url": "https://www.uniprot.org/uniprot/B5DF37" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B5DF37", "url": "https://www.uniprot.org/uniprot/B5DF37" } ], "pmid": "" }, { "name": "transcription factor TFIID complex", "id": "GO:0005669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005669", "evidence": [ { "database": "UniProtKB", "id": "B5DF37", "url": "https://www.uniprot.org/uniprot/B5DF37" } ], "pmid": "" }, { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "B5DF37", "url": "https://www.uniprot.org/uniprot/B5DF37" } ], "pmid": "" }, { "name": "SLIK (SAGA-like) complex", "id": "GO:0046695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046695", "evidence": [ { "database": "UniProtKB", "id": "B5DF37", "url": "https://www.uniprot.org/uniprot/B5DF37" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "B5DF37", "url": "https://www.uniprot.org/uniprot/B5DF37" } ], "pmid": "" }, { "name": "monoubiquitinated histone H2A deubiquitination", "id": "GO:0035522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035522", "evidence": [ { "database": "UniProtKB", "id": "B5DF37", "url": "https://www.uniprot.org/uniprot/B5DF37" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "B5DF37", "url": "https://www.uniprot.org/uniprot/B5DF37" } ], "pmid": "" }, { "name": "regulation of somatic stem cell population maintenance", "id": "GO:1904672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904672", "evidence": [ { "database": "UniProtKB", "id": "B5DF37", "url": "https://www.uniprot.org/uniprot/B5DF37" } ], "pmid": "" }, { "name": "monoubiquitinated histone deubiquitination", "id": "GO:0035521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035521", "evidence": [ { "database": "UniProtKB", "id": "B5DF37", "url": "https://www.uniprot.org/uniprot/B5DF37" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }