{
    "uniprot_canonical_ac": "B2RYE5-1",
    "uniprot_ac": "B2RYE5",
    "uniprot_id": "E41LB_RAT",
    "mass": {
        "chemical_mass": 59571.0,
        "monoisotopic_mass": 59571.0
    },
    "refseq": {
        "ac": "NP_001121037",
        "name": "band 4.1-like protein 4B isoform 2",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121037"
    },
    "gene_names": [
        {
            "name": "Epb41l4b",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/B2RYE5",
            "id": "B2RYE5"
        },
        {
            "name": "Epb41l4b",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121037",
            "id": "NP_001121037"
        },
        {
            "name": "Lulu2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/B2RYE5",
            "id": "B2RYE5"
        },
        {
            "name": "RGD1562988",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121037",
            "id": "NP_001121037"
        }
    ],
    "protein_names": [
        {
            "name": "Band 4.1-like protein 4B",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "B2RYE5"
        },
        {
            "name": "Erythrocyte membrane protein band 4.1-like 4B",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "B2RYE5"
        },
        {
            "name": "band 4.1-like protein 4B isoform 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121037",
            "id": "NP_001121037"
        },
        {
            "name": "band 4.1-like protein 4B",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121037",
            "id": "NP_001121037"
        }
    ],
    "function": [
        {
            "annotation": "Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18. Involved in the regulation of the circumferential actomyosin belt in epithelial cells. Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing. May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "B2RYE5",
                    "url": "https://www.uniprot.org/uniprot/B2RYE5#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q9H329",
                    "url": "https://www.uniprot.org/uniprot/Q9H329#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q9JMC8",
                    "url": "https://www.uniprot.org/uniprot/Q9JMC8#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "B2RYE5",
                    "url": "https://www.uniprot.org/uniprot/B2RYE5"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Epb41l4b",
            "url": "https://www.uniprot.org/uniprot/B2RYE5",
            "locus": {
                "chromosome": "5",
                "start_pos": 71694331,
                "end_pos": 71851990,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000056550",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000056550"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000056550",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000056550",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd13186",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13186",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd14473",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd17204",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17204",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "500464",
            "url": "https://www.ncbi.nlm.nih.gov/gene/500464",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000299",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR000798",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000798",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR011993",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR014352",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR014847",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR014847",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018979",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018979",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018980",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018980",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR019747",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019747",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR019748",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR019749",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR029071",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR030698",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR030698",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR035963",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:500464",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:500464",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "CPADGMD",
            "url": "https://omabrowser.org/oma/group/CPADGMD/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "3682543at2759",
            "url": "http://www.orthodb.org/?query=3682543at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23280",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23280",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23280:SF18",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23280:SF18",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00373",
            "url": "http://pfam.xfam.org/family/PF00373",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF08736",
            "url": "http://pfam.xfam.org/family/PF08736",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF09379",
            "url": "http://pfam.xfam.org/family/PF09379",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF09380",
            "url": "http://pfam.xfam.org/family/PF09380",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_B2RYE5",
            "url": "http://purl.obolibrary.org/obo/PR_B2RYE5",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_001121037",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121037",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1562988",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1562988",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A0G2JU16",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JU16",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2JU16-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JU16-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2K3H4",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K3H4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2K3H4-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K3H4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6A1T8",
            "url": "https://www.uniprot.org/uniprot/A0A8I6A1T8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6A1T8-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6A1T8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6AAH9",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AAH9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6AAH9-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AAH9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "B2RYE5",
            "url": "https://www.uniprot.org/uniprot/B2RYE5",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "B2RYE5-1",
            "url": "https://www.uniprot.org/uniprot/B2RYE5-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSVLPAAPGGSVFPAGGGPLLTGGAAVHISASGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVTHWLDHSKPIKKQMKVGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKEYRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPSNSKSARSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSRRHSTFKASNPVIAAQLCSKTNPEVHNYQPQFHPNVHPSQPRWRPHSPNVSNHSTCKQNKPSFQDDRPHWKASASGDDGHFDYVHDQNQRNLGGAYSVTYRDKLMTAL",
        "length": 527,
        "header": "sp|B2RYE5-1|E41LB_RAT Isoform 1 of Band 4.1-like protein 4B  OS=Rattus norvegicus OX=10116 GN=Epb41l4b PE=2 SV=1 CANONICAL=B2RYE5-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2JU16-1",
            "url": "",
            "sequence": {
                "sequence": "MLRFLRRTFARSMQRYAGAAGRGPPGWDERDGPRGGPAASSSAPAAPGGSVFPAGGGPLLTGGAAVHISASGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVTHWLDHSKPIKKQMKVGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKEYRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPSNSKSARSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSRRHSTFKASNPVIAAQLCSKTNPEVHNYQPQFHPNVHPSQPRWRPHSPNVSNHSTCKQNKPSFQDDRPHWKASASGDDGHFDYVHDQNQRNLGGAYSVTYRDKLMTAL",
                "length": 520,
                "header": "tr|A0A0G2JU16-1|E41LB_RAT Computationally mapped isoform of Band 4.1-like protein 4B  OS=Rattus norvegicus OX=10116 GN=Epb41l4b PE=2 SV=1 CANONICAL=B2RYE5-1"
            },
            "locus": {
                "chromosome": "5",
                "start_pos": 71851978,
                "end_pos": 71766870,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000088169",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000088169"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000068924",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000068924"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A0G2K3H4-1",
            "url": "",
            "sequence": {
                "sequence": "MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSVLPAAPGGSVFPAGGGPLLTGGAAVHISASGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVTHWLDHSKPIKKQMKVGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKEYRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPSNSKSARSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSRRHSTFKASNPVIAAQLCSKTNPEVHNYQPQFHPNVHPSQPRWRPHSPNVSYPLPSPALSPTERLPFGLEENGGTPFAPKASGRHHHQHQHHSNYGLSLTLENKEAPLRSPNSSKALTKLSPGAPALYSEAAAHLKKLELDTVKAAGPWPALHININKAEEKKVSEKTLQTPLLPSPVADHVKCNILKAQLENASRVNAQIGKEEPSFVNINKKSSLQDTNVRSPIPIRVEAAQPAVEKPEIKPPRVRRLTRQYSFDEDDLPPDLAEAVGATTATTTNTTMSATQVSVSLASPKIQQVSSPQKSEVKSPLSPGAKSPSDHGGTFTLGPGDLLMDFTEATPLAEPASSPHCAHSRCSPPLSLPMKEETTGVCMYPPIKTRLIKTFPAEPMMNPFPDPFATGPQFAADFRENKLQCCPGQSSPLIPTATLRPLTETVATVQTIYTSRKPVSLAASAETLRQELEREKMMKRLLMTEL",
                "length": 894,
                "header": "tr|A0A0G2K3H4-1|A0A0G2K3H4_RAT Computationally mapped isoform of Erythrocyte membrane protein band 4.1 like 4B  OS=Rattus norvegicus OX=10116 GN=Epb41l4b PE=1 SV=2 CANONICAL=B2RYE5-1"
            },
            "locus": {
                "chromosome": "5",
                "start_pos": 71851978,
                "end_pos": 71695483,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000090366.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000090366.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000072639.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000072639.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6A1T8-1",
            "url": "",
            "sequence": {
                "sequence": "MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSVLPAAPGGSVFPAGGGPLLTGGAAVHISASGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVTHWLDHSKPIKKQMKVGPAYALHFRVKYYSSEPNNLREEFTRLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKEYRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPSNSKSARSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSRRHSTFKGCRGSKTNPEVHNYQPQFHPNVHPSQPRWRPHSPNVSNHSTCKQNKPSFQDDRPHWKASASGDDGHFDYVHDQNQRNLGGAYSVTYRDKLMTAL",
                "length": 505,
                "header": "tr|A0A8I6A1T8-1|E41LB_RAT Computationally mapped isoform of Band 4.1-like protein 4B  OS=Rattus norvegicus OX=10116 GN=Epb41l4b PE=2 SV=1 CANONICAL=B2RYE5-1"
            },
            "locus": {
                "chromosome": "5",
                "start_pos": 71851978,
                "end_pos": 71766870,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000112787.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000112787.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000086223.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000086223.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6AAH9-1",
            "url": "",
            "sequence": {
                "sequence": "MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSVLPAAPGGSVFPAGGGPLLTGGAAVHISASGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVTHWLDHSKPIKKQMKVGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKEYRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPSNSKSARSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSRRHSTFKASNPVIAAQLCSKTNPEVHNYQPQFHPNVHPSQPRWRPHSPNVSYPLPSPALSPTERLPFGLEENGGTPFAPKASGRHHHQHQHHSNYGLSLTLENKEAPLRSPNSSKALTKLSPGAPALYSEAAAHLKKLELDTVKAAGPWPALHININKAEEKKVSEKTLQTPLLPSPVADHVKCNILKAQLENASRVNAQIGKEEPSFVNINKKSSLQDTNVRSPIPIRVEAAQPAVEKPEIKPPRVRRLTRQYSFDEDDLPPDLAEAVGATTATTTNTTMSATQVSVSLASPKIQQVSSPQKSEVKSPLSPGAKSPSDHGGTFTLGPGDLLMDFTEATPLIKTFPAEPMMNPFPDPFATGPQFAADFRENKLQCCPGQSSPLIPTATLRPLTETVATVQTIYTSRKPVSLAASAETLRQELEREKMMKRLLMTEL",
                "length": 855,
                "header": "tr|A0A8I6AAH9-1|E41LB_RAT Computationally mapped isoform of Band 4.1-like protein 4B  OS=Rattus norvegicus OX=10116 GN=Epb41l4b PE=2 SV=1 CANONICAL=B2RYE5-1"
            },
            "locus": {
                "chromosome": "5",
                "start_pos": 71851978,
                "end_pos": 71695483,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000102034.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000102034.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000088752.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000088752.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "B2RYE5-1",
            "url": "",
            "sequence": {
                "sequence": "MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSVLPAAPGGSVFPAGGGPLLTGGAAVHISASGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVTHWLDHSKPIKKQMKVGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKEYRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPSNSKSARSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSRRHSTFKASNPVIAAQLCSKTNPEVHNYQPQFHPNVHPSQPRWRPHSPNVSNHSTCKQNKPSFQDDRPHWKASASGDDGHFDYVHDQNQRNLGGAYSVTYRDKLMTAL",
                "length": 527,
                "header": "sp|B2RYE5-1|E41LB_RAT Isoform 1 of Band 4.1-like protein 4B  OS=Rattus norvegicus OX=10116 GN=Epb41l4b PE=2 SV=1 CANONICAL=B2RYE5-1"
            },
            "locus": {
                "chromosome": "5",
                "start_pos": 71851978,
                "end_pos": 71766870,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000088169",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000088169"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000068924",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000068924"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:500464",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:500464",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q9H329-1",
            "protein_name": "Band 4.1-like protein 4B",
            "gene_name": "EPB41L4B",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSALPAAPGGSVFPAGGGPLLTGGAAVHISAAGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVAHWLDHAKPIKKQMKIGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKECRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPGNSKSNRSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSRRHSTFKASNPVIAAQLCSKTNPEVHNYQPQYHPNIHPSQPRWHPHSPNVSYPLPSPVLSSSDRLPFGIEENGGTPFLTAASGRHHHQHQHQHQHQHHSNYSLSLTLENKEGPLRSPNSSSKSLTKLSPGTPALFSEAAAHLKKLELETVKAAGPWPPLHININKAEEKKVSEKTLQTPLLPSPVADHVKCNILKAQLENASRVNIQGGKEESPFVNINKKSSLQDASVRSPIPIRVETAQPAVEKPEIKPPRVRKLTRQYSFDEDDLPPDLAEAVGVTTSTTTNTTTAATQVSVPLPSPKVQNVSSPHKSEGKGLLSPGAKSPSDRGGAFTLEPGDLLMDFTEATPLAEPASNPHCAHSRCSPPLSLPMKEETTGVCMYPPIKTRLIKTFPVDTMNPFPDTFTTGPQFTADFRDSKLQCCPGPTSPLIPAATLRPLTETVSTVQTIYTTRKPVSLAASAETLRQELEREKMMKRLLMTEL",
                "length": 900
            },
            "evidence": [
                {
                    "id": "45234929",
                    "url": "http://www.informatics.jax.org/homology/45234929",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9JMC8-1",
            "protein_name": "Band 4.1-like protein 4B",
            "gene_name": "Epb41l4b",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSVLPAAPGGSVFPAGGGPLLTGGAAVHISASGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVTHWLDHAKPIKKQMKVGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKEYRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPSNSKSARSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSRRHSTFKASNPVIAAQLCSKANPEVHNYQPQYHPDVHPSQPRWRPHSPNVSNHSICKQNKPCFQDDRPHWKTSASGDGSHFDYVQDQNQRNLGGAYSVTYRDKLMTAL",
                "length": 527
            },
            "evidence": [
                {
                    "id": "45234929",
                    "url": "http://www.informatics.jax.org/homology/45234929",
                    "database": "MGI"
                },
                {
                    "id": "B2RYE5",
                    "url": "https://omabrowser.org/oma/group/B2RYE5/",
                    "database": "OMA"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 6,
                "go_terms": [
                    {
                        "name": "cytoskeleton",
                        "id": "GO:0005856",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B2RYE5",
                                "url": "https://www.uniprot.org/uniprot/B2RYE5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytosol",
                        "id": "GO:0005829",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B2RYE5",
                                "url": "https://www.uniprot.org/uniprot/B2RYE5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B2RYE5",
                                "url": "https://www.uniprot.org/uniprot/B2RYE5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "apical part of cell",
                        "id": "GO:0045177",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B2RYE5",
                                "url": "https://www.uniprot.org/uniprot/B2RYE5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B2RYE5",
                                "url": "https://www.uniprot.org/uniprot/B2RYE5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "bicellular tight junction",
                        "id": "GO:0005923",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B2RYE5",
                                "url": "https://www.uniprot.org/uniprot/B2RYE5"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "cytoskeletal protein binding",
                        "id": "GO:0008092",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008092",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B2RYE5",
                                "url": "https://www.uniprot.org/uniprot/B2RYE5"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 5,
                "go_terms": [
                    {
                        "name": "positive regulation of gene expression",
                        "id": "GO:0010628",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B2RYE5",
                                "url": "https://www.uniprot.org/uniprot/B2RYE5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of cell adhesion",
                        "id": "GO:0045785",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045785",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B2RYE5",
                                "url": "https://www.uniprot.org/uniprot/B2RYE5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of keratinocyte migration",
                        "id": "GO:0051549",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051549",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B2RYE5",
                                "url": "https://www.uniprot.org/uniprot/B2RYE5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "actomyosin structure organization",
                        "id": "GO:0031032",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031032",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B2RYE5",
                                "url": "https://www.uniprot.org/uniprot/B2RYE5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "wound healing",
                        "id": "GO:0042060",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042060",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "B2RYE5",
                                "url": "https://www.uniprot.org/uniprot/B2RYE5"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 234,
            "end_pos": 236,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 468,
            "end_pos": 470,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 471,
            "end_pos": 473,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [
        {
            "annotation": "May be negatively regulated by phosphorylation.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "B2RYE5",
                    "url": "https://www.uniprot.org/uniprot/B2RYE5"
                },
                {
                    "database": "PubMed",
                    "id": "Q9JMC8",
                    "url": "https://glygen.org/publication/PubMed/Q9JMC8"
                }
            ]
        }
    ],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
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                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
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                },
                {
                    "field": "n_linked_glycans",
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                },
                {
                    "field": "n_linked_glycan_sites",
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                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
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                {
                    "field": "total_sites",
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                {
                    "field": "n_linked_glycans",
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                {
                    "field": "n_linked_glycan_sites",
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                {
                    "field": "o_linked_glycans",
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                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
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                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
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                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
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                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
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                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
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                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
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                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv",
            "table_stats": [
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                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
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                    "field": "total",
                    "count": 0
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                {
                    "field": "total_sites",
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            ],
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        },
        {
            "table_id": "snv_non_disease",
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                    "field": "total",
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                    "field": "total_sites",
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            "sort_fields": []
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        {
            "table_id": "publication",
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                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}