{ "uniprot_canonical_ac": "A8DYV5-1", "uniprot_ac": "A8DYV5", "uniprot_id": "A8DYV5_DROME", "mass": { "chemical_mass": 265504.0, "monoisotopic_mass": 265504.0 }, "refseq": { "ac": "NP_608921", "name": "nuclear receptor coactivator 6, isoform C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608921" }, "gene_names": [ { "name": "Ncoa6", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A8DYV5", "id": "A8DYV5" }, { "name": "CG14023", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A8DYV5", "id": "A8DYV5" }, { "name": "CG1402; CG14023; Dmel\\CG14023; dNCOA6; NcoA6; NCOA6", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608921", "id": "NP_608921" }, { "name": "CG1402", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A8DYV5", "id": "A8DYV5" }, { "name": "Dmel\\CG14023", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A8DYV5", "id": "A8DYV5" }, { "name": "Dmel_CG14023", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A8DYV5", "id": "A8DYV5" }, { "name": "NCOA6", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A8DYV5", "id": "A8DYV5" }, { "name": "NcoA6", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A8DYV5", "id": "A8DYV5" }, { "name": "Ncoa6", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608921", "id": "NP_608921" }, { "name": "dNCOA6", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A8DYV5", "id": "A8DYV5" } ], "protein_names": [ { "name": "CG14023-PC; Ncoa6-PC", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608921", "id": "NP_608921" }, { "name": "CG14023-PD; Ncoa6-PD", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245884", "id": "NP_001245884" }, { "name": "CG14023-PF; Ncoa6-PF", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097088", "id": "NP_001097088" }, { "name": "Nuclear receptor coactivator 6, isoform F", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A8DYV5" }, { "name": "nuclear receptor coactivator 6, isoform C", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608921", "id": "NP_608921" }, { "name": "nuclear receptor coactivator 6, isoform D", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245884", "id": "NP_001245884" }, { "name": "nuclear receptor coactivator 6, isoform F", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097088", "id": "NP_001097088" } ], "function": [], "disease": [ { "disease_id": "DOID:12930", "recommended_name": { "id": "DOID:12930", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently." }, "synonyms": [ { "id": "DOID:12930", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:12930", "name": "primary dilated cardiomyopathy", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy 1A", "description": "Familial dilated cardiomyopathy with conduction defect due to LMNA mutation is a rare familial dilated cardiomyopathy characterized by left ventricular enlargement and/or reduced systolic function preceded or accompanied by significant conduction system disease and/or arrhythmias including bradyarrhythmias, supraventricular or ventricular arrhythmias. Disease onset is usually in early to mid-adulthood. Sudden cardiac death may occur and may be the presenting symptom. In some cases, it is associated with skeletal myopathy and elevated serum creatine kinase." }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "CDCD1", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "LMNA familial isolated dilated cardiomyopathy", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy dilated with conduction defect type 1", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, dilated, type 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy type 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy with conduction defect 1", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "familial dilated cardiomyopathy with conduction defect due to LMNA mutation", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "familial isolated dilated cardiomyopathy caused by mutation in LMNA", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, congestive", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, dilated, 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, dilated, with conduction defect 1", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, familial idiopathic", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, idiopathic dilated", "description": "" }, { "id": "MIM:115200", "resource": "MIM", "url": "https://www.omim.org/entry/115200", "name": "Cardiomyopathy, dilated, 1A", "description": "Cardiomyopathy, dilated, 1A" } ], "evidence": [ { "id": "12930", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ] }, { "disease_id": "DOID:1324", "recommended_name": { "id": "DOID:1324", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung." }, "synonyms": [ { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "LNCR1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "LNCR3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "adenocarcinoma of lung, susceptibility to", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "LNCR4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "lung cancer susceptibility 5", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "LNCR5", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "lung cancer susceptibility 5", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "A malignant neoplasm involving the lung." }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "cancer of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, resistance to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, 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mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "Nonsmall cell lung cancer", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "alveolar cell carcinoma", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, protection against", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung neoplasm", "description": "" }, { "id": "MIM:211980", "resource": "MIM", "url": "https://www.omim.org/entry/211980", "name": "Lung cancer", "description": "Lung cancer" } ], "evidence": [ { "id": "1324", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ] }, { "disease_id": "DOID:1612", "recommended_name": { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "breast cancer", "description": "A thoracic cancer that originates in the mammary gland." }, "synonyms": [ { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "breast tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "malignant neoplasm of breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "malignant tumor of the breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "mammary cancer", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "mammary tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1612", "name": "primary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "Breast carcinoma that has developed in relatives of patients with history of breast carcinoma." }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast 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"strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031698", "url": "https://www.ensembl.org/id/FBgn0031698" } ] } } ], "crossref": [ { "id": "FBgn0031698", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031698", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031698", "url": "https://flybase.org/reports/FBgn0031698", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33761", "url": "https://www.ncbi.nlm.nih.gov/gene/33761", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VMS2", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VMS2*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR026638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG14023", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG14023", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EHSILEH", "url": "https://omabrowser.org/oma/group/EHSILEH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "5404210at2759", "url": "http://www.orthodb.org/?query=5404210at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15690", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15690", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15690:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15690:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16148", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16148", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001097088", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097088", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A8DYV5", "url": "https://www.uniprot.org/uniprot/A8DYV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8DYV5-1", "url": "https://www.uniprot.org/uniprot/A8DYV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9NES4", "url": "https://www.uniprot.org/uniprot/M9NES4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9NES4-1", "url": "https://www.uniprot.org/uniprot/M9NES4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VMS2", "url": "https://www.uniprot.org/uniprot/Q9VMS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VMS2-1", "url": "https://www.uniprot.org/uniprot/Q9VMS2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLKQQLEPSLVRILVSLPWDAAQRLRQLANDGNPELRALNIQSVQFEGDSVINLKVGGQDIKITKDNVNETLEAAGSLSGNKSGLLATGFDGPSTSKAASAFMQQQQQRILQQPQNDAISLQQRRAAAAGLGLQKMPLHTTQQQQQQQQQQQVAVTPAVFKSPNTVCPMEGKVPLLLPSPSATRDFPFESMRQARVLQGREAGGLGPPLPPPPPPNVTLKVLKTQQQQAPQNGELTPTTPTSAAPTPPGSKSQFIQPPPPPYPGLGAATASSVSSPIAIAGVSAKPAIVTAPSQLNHPLGHPPLPTATSTGSNNIAISSPLLVNLLQNDGNGMSNPNQLKSPQQQQQQSPLIGMSPSGAQMMNSPMRSSGPATPSDFLMGDVLSPVVPSSPTTPQAAAPPCPPPVVMRNLQQQQQQHQQAMLSPSGNANHLYTQQQQQGPQQQQPQQQQQGPPHRFQQQHQQMSPQAVALRQQQLQRQQQMRFMQPQQQLQGQQQPQQQFQPAPDCFNNMGMGPMQQQQIRHQLRPGGLPLAPPPPHPQQQQQQRLMGLSMPQASPQQQFMSGASPLGPALSPASSHHSMHSPLMSNHQAQQQQQPQMVSPAATPGPTAPSEMAGQLMPANQHVPAAPPPDYNQAAVNSRWPLAGINKPMDSATKSSFQEFTRYQMQYNLQQQQQQVSLPGQPQQQQQQPQQQQLPPPALPTQQQQQQQSHVQQPQVAGQTQGQVDSLISLSVLDTLTTNDLDALLPTLNCDLDSTLSLEDKNELESLLQDAKDLDLDLIEDNLSAVDMRDALNTLQEAPLEQQQQQQQQQAAMQPQQQTAQMMQMPYQQQPQQQQQMQQQLMMQQQQRQQQLPQMQQRQQQHLQRQLQLQQQQQQQQQQQLQIVQRQQQQQQSQLQVQHPQQPQRPPQKQFIINPHTGDMEPMASDDSETEAEEETAQPQFRNSHSGLGSFNFNPANDMLLPTNLFSEEDSNSAQQHPMGISSDQERSRDSLASNKSATSRARKTPVSKANHSNFSAGDNSPRSSNSSPLIGLNSPQSVNANAGGAPSKKAKPNLLRGKLQQGVKERKAKDPTAAPKQKRERAKGNVKTKAAEEKIKLRLKLEKVETTPAAGAGYEGQIIINQQQQQTIVVNNHMQQLPMQTQLLALPTQQQQQQQQQQQQQQQQMQQPQMQISQQQHQQQQQTSQLQQQPAQLQQQQPQQQQQQPIQQQQQHHPVYSNFQQQQQQQQQQQQNVPGPNEPRVPPLQIRLRGKNHVVVKNTRKDRKKGQNQEASIDERQLKRSYSDQPPQQLLMDPAESKQAKLTPPPHVNGLPILIQKTTATVASPQLPQQLQGGVATTTKTTTIVAGKNGLTISAIVEAHKAQAQAQAQSLNDPQLIVGSTNTGTTPTSTTLQQQQLSKIATSLPSSITLSAINSNNNNNNVNSGNNNNRLLTMKNPIKTAATITPIVGGKPMTKNHKPPPYITAVQQLQLQKQQQQQQQQQQQQQQQQQQQQQRQLAAAVTMLPSATTLKRVEITKVTPQVTAEQAPSINPSPVVVAAAATATLTTSSTPTTQTTQLICDRKLPVAMPPMTTVNNVVVATVNSSSAALSTLSSVSTASSASIITTSTSTSSPAALPSTLRNSPASNGSGTPGHGNNGGGEDSGIESMDALSEKSPHQLSSSSPIQVSKAAVTMVQQQQQQTNAIVTITTSAAVIAPVIAPTSTQAGTTPTVAPSLQQQQKQQADDEIEKALAKMEGDFPDDLEDIVSSMIKETSECASAAGGGFLNSLESSLPAATVATVVSTASTNTSSIGSIKLNGEHHILEHDDLIKKLTESKPPAIKVKLEEMPPLLTIKKEPVIKPMASGLKVEAKVEVKLEPKVEPKSEEKLQEKPPSESSSASLQPISIEIPAQVDGETPRIRTRASSRLESPLDAQKASPDPTTVTGVSTTAATAANASTTVKSLSRASSTASPRVVTPTPNHNNNNNKRRRQESECGSSNDGADLGENSIKRPRISSGTTSNNNATETAAEHNAGAGLPKKVEIESSDSDEPLIEVAGKVRNSKQAQVEAADAAAVGVEKHVTRRNAQQLQPPQNKTAGNHAPSSTPALGTPRSGKAQAPVGATSAANNNHNSSTANNASVVPSSVTTTTMPGGAVVTTSQVNSGTSVVHATRGATAAAASTTNNNSASSPTDEKIGTRRSVRASAAANKIIYSRSNAAAAAAAAAAAAEPKGTTGKAGAAVGANNAGNVESVAEARRKTRSAVIGESMLTEGRRRRTSRDYKXPEFCALAKGLNHPSDAHEDDLLELFKDFEQQQQPHQQQQQQLEISSSSFPLAQAQDEDGDEMAEYENLARAAGGYMEEADHLLSYHSSSSAADVEVDEVLMPELDNATALDCASFVDYDEFNLCLNNILSEEDDSGSARGGGGGVSSMATKHQQSWRDAGDVLNIVQLSNDLGLSFQEFASEATTADEQRSASSSSPQLA", "length": 2467, "header": "tr|A8DYV5-1|A8DYV5_DROME Isoform 1 of Nuclear receptor coactivator 6, isoform F OS=Drosophila melanogaster OX=7227 GN=Ncoa6 PE=4 SV=2 CANONICAL=A8DYV5-1" }, "isoforms": [ { "isoform_ac": "A8DYV5-1", "url": "", "sequence": { "sequence": "MPLKQQLEPSLVRILVSLPWDAAQRLRQLANDGNPELRALNIQSVQFEGDSVINLKVGGQDIKITKDNVNETLEAAGSLSGNKSGLLATGFDGPSTSKAASAFMQQQQQRILQQPQNDAISLQQRRAAAAGLGLQKMPLHTTQQQQQQQQQQQVAVTPAVFKSPNTVCPMEGKVPLLLPSPSATRDFPFESMRQARVLQGREAGGLGPPLPPPPPPNVTLKVLKTQQQQAPQNGELTPTTPTSAAPTPPGSKSQFIQPPPPPYPGLGAATASSVSSPIAIAGVSAKPAIVTAPSQLNHPLGHPPLPTATSTGSNNIAISSPLLVNLLQNDGNGMSNPNQLKSPQQQQQQSPLIGMSPSGAQMMNSPMRSSGPATPSDFLMGDVLSPVVPSSPTTPQAAAPPCPPPVVMRNLQQQQQQHQQAMLSPSGNANHLYTQQQQQGPQQQQPQQQQQGPPHRFQQQHQQMSPQAVALRQQQLQRQQQMRFMQPQQQLQGQQQPQQQFQPAPDCFNNMGMGPMQQQQIRHQLRPGGLPLAPPPPHPQQQQQQRLMGLSMPQASPQQQFMSGASPLGPALSPASSHHSMHSPLMSNHQAQQQQQPQMVSPAATPGPTAPSEMAGQLMPANQHVPAAPPPDYNQAAVNSRWPLAGINKPMDSATKSSFQEFTRYQMQYNLQQQQQQVSLPGQPQQQQQQPQQQQLPPPALPTQQQQQQQSHVQQPQVAGQTQGQVDSLISLSVLDTLTTNDLDALLPTLNCDLDSTLSLEDKNELESLLQDAKDLDLDLIEDNLSAVDMRDALNTLQEAPLEQQQQQQQQQAAMQPQQQTAQMMQMPYQQQPQQQQQMQQQLMMQQQQRQQQLPQMQQRQQQHLQRQLQLQQQQQQQQQQQLQIVQRQQQQQQSQLQVQHPQQPQRPPQKQFIINPHTGDMEPMASDDSETEAEEETAQPQFRNSHSGLGSFNFNPANDMLLPTNLFSEEDSNSAQQHPMGISSDQERSRDSLASNKSATSRARKTPVSKANHSNFSAGDNSPRSSNSSPLIGLNSPQSVNANAGGAPSKKAKPNLLRGKLQQGVKERKAKDPTAAPKQKRERAKGNVKTKAAEEKIKLRLKLEKVETTPAAGAGYEGQIIINQQQQQTIVVNNHMQQLPMQTQLLALPTQQQQQQQQQQQQQQQQMQQPQMQISQQQHQQQQQTSQLQQQPAQLQQQQPQQQQQQPIQQQQQHHPVYSNFQQQQQQQQQQQQNVPGPNEPRVPPLQIRLRGKNHVVVKNTRKDRKKGQNQEASIDERQLKRSYSDQPPQQLLMDPAESKQAKLTPPPHVNGLPILIQKTTATVASPQLPQQLQGGVATTTKTTTIVAGKNGLTISAIVEAHKAQAQAQAQSLNDPQLIVGSTNTGTTPTSTTLQQQQLSKIATSLPSSITLSAINSNNNNNNVNSGNNNNRLLTMKNPIKTAATITPIVGGKPMTKNHKPPPYITAVQQLQLQKQQQQQQQQQQQQQQQQQQQQQRQLAAAVTMLPSATTLKRVEITKVTPQVTAEQAPSINPSPVVVAAAATATLTTSSTPTTQTTQLICDRKLPVAMPPMTTVNNVVVATVNSSSAALSTLSSVSTASSASIITTSTSTSSPAALPSTLRNSPASNGSGTPGHGNNGGGEDSGIESMDALSEKSPHQLSSSSPIQVSKAAVTMVQQQQQQTNAIVTITTSAAVIAPVIAPTSTQAGTTPTVAPSLQQQQKQQADDEIEKALAKMEGDFPDDLEDIVSSMIKETSECASAAGGGFLNSLESSLPAATVATVVSTASTNTSSIGSIKLNGEHHILEHDDLIKKLTESKPPAIKVKLEEMPPLLTIKKEPVIKPMASGLKVEAKVEVKLEPKVEPKSEEKLQEKPPSESSSASLQPISIEIPAQVDGETPRIRTRASSRLESPLDAQKASPDPTTVTGVSTTAATAANASTTVKSLSRASSTASPRVVTPTPNHNNNNNKRRRQESECGSSNDGADLGENSIKRPRISSGTTSNNNATETAAEHNAGAGLPKKVEIESSDSDEPLIEVAGKVRNSKQAQVEAADAAAVGVEKHVTRRNAQQLQPPQNKTAGNHAPSSTPALGTPRSGKAQAPVGATSAANNNHNSSTANNASVVPSSVTTTTMPGGAVVTTSQVNSGTSVVHATRGATAAAASTTNNNSASSPTDEKIGTRRSVRASAAANKIIYSRSNAAAAAAAAAAAAEPKGTTGKAGAAVGANNAGNVESVAEARRKTRSAVIGESMLTEGRRRRTSRDYKXPEFCALAKGLNHPSDAHEDDLLELFKDFEQQQQPHQQQQQQLEISSSSFPLAQAQDEDGDEMAEYENLARAAGGYMEEADHLLSYHSSSSAADVEVDEVLMPELDNATALDCASFVDYDEFNLCLNNILSEEDDSGSARGGGGGVSSMATKHQQSWRDAGDVLNIVQLSNDLGLSFQEFASEATTADEQRSASSSSPQLA", "length": 2467, "header": "tr|A8DYV5-1|A8DYV5_DROME Isoform 1 of Nuclear receptor coactivator 6, isoform F OS=Drosophila melanogaster OX=7227 GN=Ncoa6 PE=4 SV=2 CANONICAL=A8DYV5-1" }, "locus": { "chromosome": "2L", "start_pos": 5325966, "end_pos": 5317213, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0329969", "url": "https://www.ensembl.org/id/FBtr0329969" }, { "database": "Ensembl Peptide", "id": "FBpp0303004", "url": "https://www.ensembl.org/id/FBpp0303004" } ] } }, { "isoform_ac": "M9NES4-1", "url": "", "sequence": { "sequence": "MPLKQQLEPSLVRILVSLPWDAAQRLRQLANDGNPELRALNIQSVQFEGDSVINLKVGGQDIKITKDNVNETLEAAGSLSGNKSGLLATGFDGPSTSKAASAFMQQQQQRILQQPQNDAISLQQRRAAAAGLGLQKMPLHTTQQQQQQQQQQQVAVTPAVFKSPNTVCPMEGKVPLLLPSPSATRDFPFESMRQARVLQGREAGGLGPPLPPPPPPNVTLKVLKTQQQQAPQNGELTPTTPTSAAPTPPGSKSQFIQPPPPPYPGLGAATASSVSSPIAIAGVSAKPAIVTAPSQLNHPLGHPPLPTATSTGSNNIAISSPLLVNLLQNDGNGMSNPNQLKSPQQQQQQSPLIGMSPSGAQMMNSPMRSSGPATPSDFLMGDVLSPVVPSSPTTPQAAAPPCPPPVVMRNLQQQQQQHQQAMLSPSGNANHLYTQQQQQGPQQQQPQQQQQGPPHRFQQQHQQMSPQAVALRQQQLQRQQQMRFMQPQQQLQGQQQPQQQFQPAPDCFNNMGMGPMQQQQIRHQLRPGGLPLAPPPPHPQQQQQQRLMGLSMPQASPQQQFMSGASPLGPALSPASSHHSMHSPLMSNHQAQQQQQPQMVSPAATPGPTAPSEMAGQLMPANQHVPAAPPPDYNQAAVNSRWPLAGINKPMDSATKSSFQEFTRYQMQYNLQQQQQQVSLPGQPQQQQQQPQQQQLPPPALPTQQQQQQQSHVQQPQVAGQTQGQVDSLISLSVLDTLTTNDLDALLPTLNCDLDSTLSLEDKNELESLLQDAKDLDLDLIEDNLSAVDMRDALNTLQEAPLEQQQQQQQQQAAMQPQQQTAQMMQMPYQQQPQQQQQMQQQLMMQQQQRQQQLPQMQQRQQQHLQRQLQLQQQQQQQQQQQLQIVQRQQQQQQSQLQVQHPQQPQRPPQKQFIINPHTGDMEPMASDDSETEAEEETAQPQFRNSHSGLGSFNFNPANDMLLPTNLFSEEDSNSAQQHPMGISSDQERSRDSLASNKSATSRARKTPVSKANHSNFSAGDNSPRSSNSSPLIGLNSPQSVNANAGGAPSKKAKPNLLRGKLQQGVKERKAKDPTAAPKQKRERAKGNVKTKAAEEKIKLRLKLEKVETTPAAGAGYEGQIIINQQQQQTIVVNNHMQQLPMQTQLLALPTQQQQQQQQQQQQQQQQMQQPQMQISQQQHQQQQQTSQLQQQPAQLQQQQPQQQQQQPIQQQQQHHPVYSNFQQQQQQQQQQQQNVPGPNEPRVPPLQIRLRGKNHVVVKNTRKDRKKGQNQEASIDERQLKRSYSDQPPQQLLMDPAESKQAKLTPPPHVNGLPILIQKTTATVASPQLPQQLQGGVATTTKTTTIVAGKNGLTISAIVEAHKAQAQAQAQSLNDPQLIVGSTNTGTTPTSTTLQQQQLSKIATSLPSSITLSAINSNNNNNNVNSGNNNNRLLTMKNPIKTAATITPIVGGKPMTKNHKPPPYITAVQQLQLQKQQQQQQQQQQQQQQQQQQQQQRQLAAAVTMLPSATTLKRVEITKVTPQVTAEQAPSINPSPVVVAAAATATLTTSSTPTTQTTQLICDRKLPVAMPPMTTVNNVVVATVNSSSAALSTLSSVSTASSASIITTSTSTSSPAALPSTLRNSPASNGSGTPGHGNNGGGEDSGIESMDALSEKSPHQLSSSSPIQVSKAAVTMVQQQQQQTNAIVTITTSAAVIAPVIAPTSTQAGTTPTVAPSLQQQQKQQADDEIEKALAKMEGDFPDDLEDIVSSMIKETSECASAAGGGFLNSLESSLPAATVATVVSTASTNTSSIGSIKLNGEHHILEHDDLIKKLTESKPPAIKVKLEEMPPLLTIKKEPVIKPMASGLKVEAKVEVKLEPKVEPKSEEKLQEKPPSESSSASLQPISIEIPAQVDGETPRIRTRASSRLESPLDAQKASPDPTTVTGVSTTAATAANASTTVKSLSRASSTASPRVVTPTPNHNNNNNKRRRQESECGSSNDGADLGENSIKRPRISSGTTSNNNATETAAEHNAGAGLPKKVEIESSDSDEPLIEVAGKVRNSKQAQVEAADAAAVGVEKHVTRRNAQQLQPPQNKTAGNHAPSSTPALGTPRSGKAQAPVGATSAANNNHNSSTANNASVVPSSVTTTTMPGGAVVTTSQVNSGTSVVHATRGATAAAASTTNNNSASSPTDEKIGTRRSVRASAAANKIIYSRSNAAAAAAAAAAAAEPKGTTGKAGAAVGANNAGNVESVAEARRKTRSAVIGESMLTEGRRRRTSRDYK", "length": 2266, "header": "tr|M9NES4-1|M9NES4_DROME Computationally mapped isoform of Nuclear receptor coactivator 6, isoform D OS=Drosophila melanogaster OX=7227 GN=Ncoa6 PE=4 SV=1 CANONICAL=A8DYV5-1" }, "locus": { "chromosome": "2L", "start_pos": 5325966, "end_pos": 5317816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0307041", "url": "https://www.ensembl.org/id/FBtr0307041" }, { "database": "Ensembl Peptide", "id": "FBpp0297884", "url": "https://www.ensembl.org/id/FBpp0297884" } ] } }, { "isoform_ac": "Q9VMS2-1", "url": "", "sequence": { "sequence": "MPLKQLEPSLVRILVSLPWDAAQRLRQLANDGNPELRALNIQSVQFEGDSVINLKVGGQDIKITKDNVNETLEAAGSLSGNKSGLLATGFDGPSTSKAASAFMQQQQQRILQQPQNDAISLQQRRAAAAGLGLQKMPLHTTQQQQQQQQQQQVAVTPAVFKSPNTVCPMEGKVPLLLPSPSATRDFPFESMRQARVLQGREAGGLGPPLPPPPPPNVTLKVLKTQQQQAPQNGELTPTTPTSAAPTPPGSKSQFIQPPPPPYPGLGAATASSVSSPIAIAGVSAKPAIVTAPSQLNHPLGHPPLPTATSTGSNNIAISSPLLVNLLQNDGNGMSNPNQLKSPQQQQQQSPLIGMSPSGAQMMNSPMRSSGPATPSDFLMGDVLSPVVPSSPTTPQAAAPPCPPPVVMRNLQQQQQQHQQAMLSPSGNANHLYTQQQQQGPQQQQPQQQQQGPPHRFQQQHQQMSPQAVALRQQQLQRQQQMRFMQPQQQLQGQQQPQQQFQPAPDCFNNMGMGPMQQQQIRHQLRPGGLPLAPPPPHPQQQQQQRLMGLSMPQASPQQQFMSGASPLGPALSPASSHHSMHSPLMSNHQAQQQQQPQMVSPAATPGPTAPSEMAGQLMPANQHVPAAPPPDYNQAAVNSRWPLAGINKPMDSATKSSFQEFTRYQMQYNLQQQQQQVSLPGQPQQQQQQPQQQQLPPPALPTQQQQQQQSHVQQPQVAGQTQGQVDSLISLSVLDTLTTNDLDALLPTLNCDLDSTLSLEDKNELESLLQDAKDLDLDLIEDNLSAVDMRDALNTLQEAPLEQQQQQQQQQAAMQPQQQTAQMMQMPYQQQPQQQQQMQQQLMMQQQQRQQQLPQMQQRQQQHLQRQLQLQQQQQQQQQQQLQIVQRQQQQQQSQLQVQHPQQPQRPPQKQFIINPHTGDMEPMASDDSETEAEEETAQPQFRNSHSGLGSFNFNPANDMLLPTNLFSEEDSNSAQQHPMGISSDQERSRDSLASNKSATSRARKTPVSKANHSNFSAGDNSPRSSNSSPLIGLNSPQSVNANAGGAPSKKAKPNLLRGKLQQGVKERKAKDPTAAPKQKRERAKGNVKTKAAEEKIKLRLKLEKVETTPAAGAGYEGQIIINQQQQQTIVVNNHMQQLPMQTQLLALPTQQQQQQQQQQQQQQQQMQQPQMQISQQQHQQQQQTSQLQQQPAQLQQQQPQQQQQQPIQQQQQHHPVYSNFQQQQQQQQQQQQNVPGPNEPRVPPLQIRLRGKNHVVVKNTRKDRKKGQNQEASIDERQLKRSYSDQPPQQLLMDPAESKQAKLTPPPHVNGLPILIQKTTATVASPQLPQQLQGGVATTTKTTTIVAGKNGLTISAIVEAHKAQAQAQAQSLNDPQLIVGSTNTGTTPTSTTLQQQQLSKIATSLPSSITLSAINSNNNNNNVNSGNNNNRLLTMKNPIKTAATITPIVGGKPMTKNHKPPPYITAVQQLQLQKQQQQQQQQQQQQQQQQQQQQQRQLAAAVTMLPSATTLKRVEITKVTPQVTAEQAPSINPSPVVVAAAATATLTTSSTPTTQTTQLICDRKLPVAMPPMTTVNNVVVATVNSSSAALSTLSSVSTASSASIITTSTSTSSPAALPSTLRNSPASNGSGTPGHGNNGGGEDSGIESMDALSEKSPHQLSSSSPIQVSKAAVTMVQQQQQQTNAIVTITTSAAVIAPVIAPTSTQAGTTPTVAPSLQQQQKQQADDEIEKALAKMEGDFPDDLEDIVSSMIKETSECASAAGGGFLNSLESSLPAATVATVVSTASTNTSSIGSIKLNGEHHILEHDDLIKKLTESKPPAIKVKLEEMPPLLTIKKEPVIKPMASGLKVEAKVEVKLEPKVEPKSEEKLQEKPPSESSSASLQPISIEIPAQVDGETPRIRTRASSRLESPLDAQKASPDPTTVTGVSTTAATAANASTTVKSLSRASSTASPRVVTPTPNHNNNNNKRRRQESECGSSNDGADLGENSIKRPRISSGTTSNNNATETAAEHNAGAGLPKKVEIESSDSDEPLIEVAGKVRNSKQAQVEAADAAAVGVEKHVTRRNAQQLQPPQNKTAGNHAPSSTPALGTPRSGKAQAPVGATSAANNNHNSSTANNASVVPSSVTTTTMPGGAVVTTSQVNSGTSVVHATRGATAAAASTTNNNSASSPTDEKIGTRRSVRASAAANKIIYSRSNAAAAAAAAAAAAEPKGTTGKAGAAVGANNAGNVESVAEARRKTRSAVIGESMLTEGRRRRTSRDYK", "length": 2265, "header": "tr|Q9VMS2-1|A8DYV5_DROME Computationally mapped isoform of Nuclear receptor coactivator 6, isoform F OS=Drosophila melanogaster OX=7227 GN=Ncoa6 PE=4 SV=4 CANONICAL=A8DYV5-1" }, "locus": { "chromosome": "2L", "start_pos": 5325966, "end_pos": 5317816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0307040", "url": "https://www.ensembl.org/id/FBtr0307040" }, { "database": "Ensembl Peptide", "id": "FBpp0297883", "url": "https://www.ensembl.org/id/FBpp0297883" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS2", "url": "https://www.uniprot.org/uniprot/Q9VMS2" }, { "database": "UniProtKB", "id": "A8DYV5", "url": "https://www.uniprot.org/uniprot/A8DYV5" }, { "database": "UniProtKB", "id": "M9NES4", "url": "https://www.uniprot.org/uniprot/M9NES4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS2", "url": "https://www.uniprot.org/uniprot/Q9VMS2" }, { "database": "UniProtKB", "id": "A8DYV5", "url": "https://www.uniprot.org/uniprot/A8DYV5" }, { "database": "UniProtKB", "id": "M9NES4", "url": 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