{ "uniprot_canonical_ac": "A8DYR8-1", "uniprot_ac": "A8DYR8", "uniprot_id": "A8DYR8_DROME", "mass": { "chemical_mass": 45537.0, "monoisotopic_mass": 45537.0 }, "refseq": { "ac": "NP_001097140", "name": "uncharacterized protein, isoform C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097140" }, "gene_names": [ { "name": "CG13141", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A8DYR8", "id": "A8DYR8" }, { "name": "CG5369", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A8DYR8", "id": "A8DYR8" }, { "name": "CG13141; CG5369; Dmel\\CG34367", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260331", "id": "NP_001260331" }, { "name": "CG13141", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A8DYR8", "id": "A8DYR8" }, { "name": "CG34367", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260331", "id": "NP_001260331" }, { "name": "CG34367", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A8DYR8", "id": "A8DYR8" }, { "name": "CG5369", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A8DYR8", "id": "A8DYR8" }, { "name": "Dmel\\CG34367", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A8DYR8", "id": "A8DYR8" }, { "name": "Dmel_CG34367", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A8DYR8", "id": "A8DYR8" } ], "protein_names": [ { "name": "CG34367-PB", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162934", "id": "NP_001162934" }, { "name": "CG34367-PC", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097140", "id": "NP_001097140" }, { "name": "CG34367-PE", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260331", "id": "NP_001260331" }, { "name": "Uncharacterized protein, isoform C", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A8DYR8" }, { "name": "uncharacterized protein, isoform B", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162934", "id": "NP_001162934" }, { "name": "uncharacterized protein, isoform C", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097140", "id": "NP_001097140" }, { "name": "uncharacterized protein, isoform E", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260331", "id": "NP_001260331" } ], "function": [], "disease": [ { "disease_id": "DOID:0060847", "recommended_name": { "id": "DOID:0060847", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060847", "name": "Leri-Weill dyschondrosteosis", "description": "An osteochondrodysplasia characterized by abnormal shortening of the forearms and lower legs, abnormal misalignment of the wrist (Madelung deformity of the wrist), and associated short stature and has_material_basis_in heterozygous defects in the pseudoautosomal genes SHOX or SHOXY or by deletion of the SHOX downstream regulatory domain." }, "synonyms": [ { "id": "MONDO:0007481", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007481", "name": "Leri-Weill dyschondrosteosis", "description": "Leri-Weill dyschondrosteosis (LWD) is a skeletal dysplasia marked by disproportionate short stature and the characteristic Madelung wrist deformity." }, { "id": "MONDO:0007481", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007481", "name": "LWD", "description": "" }, { "id": "MONDO:0007481", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007481", "name": "Leri Weill dyschondrosteosis", "description": "" }, { "id": "MONDO:0007481", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007481", "name": "Leri-Weill dyschondrosteosis", "description": "" }, { "id": "MONDO:0007481", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007481", "name": "Leri-Weill dyschondrosteosis, Pseudoautosomal dominant", "description": "" }, { "id": "MONDO:0007481", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007481", "name": "Leri-Weill dyschondrostosis", "description": "" }, { "id": "MONDO:0007481", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007481", "name": "Leri-Weill syndrome", "description": "" }, { "id": "MONDO:0007481", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007481", "name": "Lri-Weill dyschondrosteosis", "description": "" }, { "id": "MONDO:0007481", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007481", "name": "Lri-Weill syndrome", "description": "" }, { "id": "MONDO:0007481", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007481", "name": "DCo", "description": "" }, { "id": "MONDO:0007481", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007481", "name": "Madelung deformity", "description": "" }, { "id": "MONDO:0007481", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007481", "name": "dyschondrosteosis", "description": "" }, { "id": "MIM:127300", "resource": "MIM", "url": "https://www.omim.org/entry/127300", "name": "Leri-Weill dyschondrosteosis", "description": "Leri-Weill dyschondrosteosis" } ], "evidence": [ { "id": "0060847", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0060847" } ] }, { "disease_id": "DOID:0112120", "recommended_name": { "id": "DOID:0112120", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0112120", "name": "SHOX-related short stature", "description": "A bone development disease characterized by height below the third percentile for chronological age that has_material_basis_in mutation in the SHOX gene or the SHOXY gene on chromosomes Xp22.33 and Yp11.2, respectively." }, "synonyms": [ { "id": "DOID:0112120", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0112120", "name": "idiopathic familial short stature", "description": "" }, { "id": "MONDO:0010367", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010367", "name": "SHOX-related short stature", "description": "SHOX-related short stature is a primary bone dysplasia characterized by a height that is 2 standard deviations below the corresponding mean height for a given age, sex and population group, in the absence of obvious skeletal abnormalities and other diseases and with normal developmental milestones. Patients present normal bone age with normal limbs, shortening of the extremities (significantly lower extremities-trunk and sitting height-to-height ratios), normal hGH values, normal karyotype, and Leri-Weill dyschondrosteosis-like radiological signs (e.g. triangularization of distal radial epiphyses, pyramidalization of distal carpal row, and lucency of the distal radius on the ulnar side). Mesomelic disproportions and Madelung deformity are not apparent at a young age, but may develop later in life or never." }, { "id": "MONDO:0010367", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010367", "name": "short stature, idiopathic familial", "description": "" }, { "id": "MONDO:0010367", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010367", "name": "ISS", "description": "" }, { "id": "MONDO:0010367", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010367", "name": "short stature, idiopathic, X-linked", "description": "" }, { "id": "MIM:300582", "resource": "MIM", "url": "https://www.omim.org/entry/300582", "name": "Short stature, idiopathic, X-linked", "description": "Short stature, idiopathic, X-linked" } ], "evidence": [ { "id": "0112120", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0112120" } ] }, { "disease_id": "DOID:1324", "recommended_name": { "id": "DOID:1324", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung." }, "synonyms": [ { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "LNCR1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "LNCR3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "adenocarcinoma of lung, susceptibility to", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "LNCR4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "lung cancer susceptibility 5", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "LNCR5", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "lung cancer susceptibility 5", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "A malignant neoplasm involving the lung." }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "cancer of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, resistance to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung neoplasm", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumor", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumour", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "Nonsmall cell lung cancer", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "alveolar cell carcinoma", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, protection against", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung neoplasm", "description": "" }, { "id": "MIM:211980", "resource": "MIM", "url": "https://www.omim.org/entry/211980", "name": "Lung cancer", "description": "Lung cancer" } ], "evidence": [ { "id": "1324", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ] }, { "disease_id": "DOID:5688", "recommended_name": { "id": "DOID:5688", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5688", "name": "Werner syndrome", "description": "A progeroid syndrome characterized by premature aging and age-related phenotypes such as atherosclerosis, arteriosclerosis, cataracts, osteoporosis, soft tissue calcification, premature thinning, graying, and loss of hair, as well as a high incidence of some types of cancers and that has_material_basis_in mutations in the WRN gene, on chromosome 8." }, "synonyms": [ { "id": "DOID:5688", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5688", "name": "WS", "description": "" }, { "id": "DOID:5688", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5688", "name": "Werner's syndrome", "description": "" }, { "id": "DOID:5688", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5688", "name": "adult premature ageing syndrome", "description": "" }, { "id": "DOID:5688", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5688", "name": "adult progeria", "description": "" }, { "id": "MONDO:0010196", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010196", "name": "Werner syndrome", "description": "A rare inherited syndrome characterized by premature aging with onset in the third decade of life and with cardinal clinical features including bilateral cataracts, short stature, graying and thinning of scalp hair, characteristic skin disorders and premature onset of additional age-related disorders." }, { "id": "MONDO:0010196", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010196", "name": "WS", "description": "" }, { "id": "MONDO:0010196", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010196", "name": "Werner syndrome", "description": "" }, { "id": "MONDO:0010196", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010196", "name": "Werner's syndrome", "description": "" }, { "id": "MONDO:0010196", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010196", "name": "adult premature ageing syndrome", "description": "" }, { "id": "MONDO:0010196", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010196", "name": "adult premature aging syndrome", "description": "" }, { "id": "MONDO:0010196", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010196", "name": "adult progeria", "description": "" }, { "id": "MONDO:0010196", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010196", "name": "WRN", "description": "" }, { "id": "MIM:277700", "resource": "MIM", "url": "https://www.omim.org/entry/277700", "name": "Werner syndrome", "description": "Werner syndrome" } ], "evidence": [ { "id": "5688", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:5688" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYR8", "url": "https://www.uniprot.org/uniprot/A8DYR8" } ], "common_name": "Fruit fly" } ], "gene": [ { "name": "CG13141", "url": "https://www.uniprot.org/uniprot/A8DYR8", "locus": { "chromosome": "2L", "start_pos": 10347851, "end_pos": 10353905, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0085396", "url": "https://www.ensembl.org/id/FBgn0085396" } ] } } ], "crossref": [ { "id": "FBgn0085396", "url": "https://bgee.org/?page=gene&gene_id=FBgn0085396", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0085396", "url": "https://flybase.org/reports/FBgn0085396", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "5740879", "url": "https://www.ncbi.nlm.nih.gov/gene/5740879", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "A2RVG7", "url": "https://www.ebi.ac.uk/intact/interactors/id:A2RVG7*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "A8DYR8", "url": "https://www.ebi.ac.uk/intact/interactors/id:A8DYR8*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG34367", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG34367", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MHKGILL", "url": "https://omabrowser.org/oma/group/MHKGILL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "2897127at2759", "url": "http://www.orthodb.org/?query=2897127at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46255", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46255", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46255:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46255:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "http://pfam.xfam.org/family/PF00046", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF03826", "url": "http://pfam.xfam.org/family/PF03826", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001097140", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097140", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2RVG7", "url": "https://www.uniprot.org/uniprot/A2RVG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2RVG7-1", "url": "https://www.uniprot.org/uniprot/A2RVG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8DYR8", "url": "https://www.uniprot.org/uniprot/A8DYR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8DYR8-1", "url": "https://www.uniprot.org/uniprot/A8DYR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9PCS1", "url": "https://www.uniprot.org/uniprot/M9PCS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9PCS1-1", "url": "https://www.uniprot.org/uniprot/M9PCS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQLAQFVTKSFEFNLTNNSVHALFNSMTGARLKKPTEVKNSIFINSISSGGSYADTCASGEESVDIDITDLSVSESNTILAIDPEPTEESHSQREEHVETYSLSPTLHKAAVEPKPKNWLISEDLDVDSQPEDPKMSGLPTASITECTEDSNTPKLAPDKPLLPEECVSPEPSRNREHCDPLDTSLVNTKQRRSRTNFTLDQLNELERLFEETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKHENQMHKGFLVGSRSPPIATPLEPCRVAPYVSLAALRSSSVPSHPAAATSSNPQAPGVSGTSSSGKVVTVDSPHNHNPAISRSAIKQFSSTVAAAAAFSAFDPAIISVAAHQYAAAITNGTVPAGLFSVPQYSINLAAFAAAHSKSSSIADLRMKAKKHSESLGLQADMVL", "length": 420, "header": "tr|A8DYR8-1|A8DYR8_DROME Isoform 1 of Uncharacterized protein, isoform C OS=Drosophila melanogaster OX=7227 GN=CG13141 PE=4 SV=1 CANONICAL=A8DYR8-1" }, "isoforms": [ { "isoform_ac": "A2RVG7-1", "url": "", "sequence": { "sequence": "MNIEKTITFSDPKMSGLPTASITECTEDSNTPKLAPDKPLLPEECVSPEPSRNREHCDPLDTSLVNTKQRRSRTNFTLDQLNELERLFEETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKHENQMHKGFLVGSRSPPIATPLEPCRVAPYVSLAALRSSSVPSHPAAATSSNPQAPGVSGTSSSGKVVTVDSPHNHNPAISRSAIKQFSSTVAAAAAFSAFDPAIISVAAHQYAAAITNGTVPAGLFSVPQYSINLAAFAAAHSKSSSIADLRMKAKKHSESLGLQADMVL", "length": 297, "header": "tr|A2RVG7-1|A8DYR8_DROME Computationally mapped isoform of Uncharacterized protein, isoform C OS=Drosophila melanogaster OX=7227 GN=CG13141 PE=4 SV=1 CANONICAL=A8DYR8-1" }, "locus": { "chromosome": "2L", "start_pos": 10352056, "end_pos": 10348020, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0301049", "url": "https://www.ensembl.org/id/FBtr0301049" }, { "database": "Ensembl Peptide", "id": "FBpp0290271", "url": "https://www.ensembl.org/id/FBpp0290271" } ] } }, { "isoform_ac": "A8DYR8-1", "url": "", "sequence": { "sequence": "MEQLAQFVTKSFEFNLTNNSVHALFNSMTGARLKKPTEVKNSIFINSISSGGSYADTCASGEESVDIDITDLSVSESNTILAIDPEPTEESHSQREEHVETYSLSPTLHKAAVEPKPKNWLISEDLDVDSQPEDPKMSGLPTASITECTEDSNTPKLAPDKPLLPEECVSPEPSRNREHCDPLDTSLVNTKQRRSRTNFTLDQLNELERLFEETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKHENQMHKGFLVGSRSPPIATPLEPCRVAPYVSLAALRSSSVPSHPAAATSSNPQAPGVSGTSSSGKVVTVDSPHNHNPAISRSAIKQFSSTVAAAAAFSAFDPAIISVAAHQYAAAITNGTVPAGLFSVPQYSINLAAFAAAHSKSSSIADLRMKAKKHSESLGLQADMVL", "length": 420, "header": "tr|A8DYR8-1|A8DYR8_DROME Isoform 1 of Uncharacterized protein, isoform C OS=Drosophila melanogaster OX=7227 GN=CG13141 PE=4 SV=1 CANONICAL=A8DYR8-1" }, "locus": { "chromosome": "2L", "start_pos": 10353631, "end_pos": 10348020, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0112592", "url": "https://www.ensembl.org/id/FBtr0112592" }, { "database": "Ensembl Peptide", "id": "FBpp0111504", "url": "https://www.ensembl.org/id/FBpp0111504" } ] } }, { "isoform_ac": "M9PCS1-1", "url": "", "sequence": { "sequence": "MNIEKTITFSDPKMSGLPTASITECTEDSNTPKLAPDKPLLPEECVSPEPSRNREHCDPLDTSLVNTKQRRSRTNFTLDQLNELERLFEETHYPDAFMREELSQRLGLSEARVQDSSWAAGVRRLPLRWNHVVWLPTSAWPPFAAHPFHPILPQRPARIPRHPVSPEPAVPARWSPWTHHIITIRRYRARLSNSFPAPWQQPPPFPLSIRPLFRWQLISTQLL", "length": 223, "header": "tr|M9PCS1-1|A8DYR8_DROME Computationally mapped isoform of Uncharacterized protein, isoform C OS=Drosophila melanogaster OX=7227 GN=CG13141 PE=4 SV=1 CANONICAL=A8DYR8-1" }, "locus": { "chromosome": "2L", "start_pos": 10352056, "end_pos": 10348184, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0333005", "url": "https://www.ensembl.org/id/FBtr0333005" }, { "database": "Ensembl Peptide", "id": "FBpp0305220", "url": "https://www.ensembl.org/id/FBpp0305220" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "M9PCS1", "url": "https://www.uniprot.org/uniprot/M9PCS1" }, { "database": "UniProtKB", "id": "A2RVG7", "url": "https://www.uniprot.org/uniprot/A2RVG7" }, { "database": "UniProtKB", "id": "A8DYR8", "url": "https://www.uniprot.org/uniprot/A8DYR8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "M9PCS1", "url": "https://www.uniprot.org/uniprot/M9PCS1" }, { "database": "UniProtKB", "id": "A2RVG7", "url": "https://www.uniprot.org/uniprot/A2RVG7" }, { "database": "UniProtKB", "id": "A8DYR8", "url": "https://www.uniprot.org/uniprot/A8DYR8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "M9PCS1", "url": "https://www.uniprot.org/uniprot/M9PCS1" }, { "database": "UniProtKB", "id": "A2RVG7", "url": "https://www.uniprot.org/uniprot/A2RVG7" }, { "database": "UniProtKB", "id": "A8DYR8", "url": "https://www.uniprot.org/uniprot/A8DYR8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "M9PCS1", "url": "https://www.uniprot.org/uniprot/M9PCS1" }, { "database": "UniProtKB", "id": "A2RVG7", "url": "https://www.uniprot.org/uniprot/A2RVG7" }, { "database": "UniProtKB", "id": "A8DYR8", "url": "https://www.uniprot.org/uniprot/A8DYR8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "M9PCS1", "url": "https://www.uniprot.org/uniprot/M9PCS1" }, { "database": "UniProtKB", "id": "A2RVG7", "url": "https://www.uniprot.org/uniprot/A2RVG7" }, { "database": "UniProtKB", "id": "A8DYR8", "url": "https://www.uniprot.org/uniprot/A8DYR8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "M9PCS1", "url": "https://www.uniprot.org/uniprot/M9PCS1" }, { "database": "UniProtKB", "id": "A2RVG7", "url": "https://www.uniprot.org/uniprot/A2RVG7" }, { "database": "UniProtKB", "id": "A8DYR8", "url": "https://www.uniprot.org/uniprot/A8DYR8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "M9PCS1", "url": "https://www.uniprot.org/uniprot/M9PCS1" }, { "database": "UniProtKB", "id": "A2RVG7", "url": "https://www.uniprot.org/uniprot/A2RVG7" }, { "database": "UniProtKB", "id": "A8DYR8", "url": "https://www.uniprot.org/uniprot/A8DYR8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "M9PCS1", "url": "https://www.uniprot.org/uniprot/M9PCS1" }, { "database": "UniProtKB", "id": "A2RVG7", "url": "https://www.uniprot.org/uniprot/A2RVG7" }, { "database": "UniProtKB", "id": "A8DYR8", "url": "https://www.uniprot.org/uniprot/A8DYR8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A2RVG7", "url": "https://www.uniprot.org/uniprot/A2RVG7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "A2RVG7", "url": "https://www.uniprot.org/uniprot/A2RVG7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "A2RVG7", "url": "https://www.uniprot.org/uniprot/A2RVG7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG34367", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG34367", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": 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