{
    "uniprot_canonical_ac": "A3KGW5-1",
    "uniprot_ac": "A3KGW5",
    "uniprot_id": "GT253_MOUSE",
    "mass": {
        "chemical_mass": 67672.0,
        "monoisotopic_mass": 67672.0
    },
    "refseq": {
        "ac": "NP_997181",
        "name": "inactive glycosyltransferase 25 family member 3 precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997181"
    },
    "gene_names": [
        {
            "name": "Cercam",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A3KGW5",
            "id": "A3KGW5"
        },
        {
            "name": "2600006K01Rik; Ceecam1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997181",
            "id": "NP_997181"
        },
        {
            "name": "Ceecam1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A3KGW5",
            "id": "A3KGW5"
        },
        {
            "name": "Cercam",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997181",
            "id": "NP_997181"
        },
        {
            "name": "Glt25d3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A3KGW5",
            "id": "A3KGW5"
        }
    ],
    "protein_names": [
        {
            "name": "Inactive glycosyltransferase 25 family member 3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "A3KGW5"
        },
        {
            "name": "Cerebral endothelial cell adhesion molecule",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A3KGW5"
        },
        {
            "name": "glycosyltransferase 25 family member 3; cerebral endothelial cell adhesion molecule 1; probable inactive glycosyltransferase 25 family member 3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997181",
            "id": "NP_997181"
        },
        {
            "name": "inactive glycosyltransferase 25 family member 3 precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997181",
            "id": "NP_997181"
        }
    ],
    "function": [
        {
            "annotation": "Probable cell adhesion protein involved in leukocyte transmigration across the blood-brain barrier. Does not express any beta-galactosyltransferase activity in vitro.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A3KGW5",
                    "url": "https://www.uniprot.org/uniprot/A3KGW5#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q5T4B2",
                    "url": "https://www.uniprot.org/uniprot/Q5T4B2#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [
        {
            "evidence": [
                {
                    "id": "rs3388537300",
                    "database": "dbSNP",
                    "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388537300"
                }
            ],
            "glycoeffect": [
                "n-glyco-sequon-loss",
                "o-glyco-site-loss"
            ],
            "start_pos": 152,
            "end_pos": 152,
            "sequence_org": "T",
            "sequence_mut": "I",
            "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-loss (NQT->NQI).",
            "chr_id": "2",
            "chr_pos": "29762612",
            "ref_nt": "T",
            "alt_nt": "null",
            "minor_allelic_frequency": "",
            "site_lbl": "T152",
            "keywords": [
                "ebi",
                "germline"
            ]
        }
    ],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A3KGW5",
                    "url": "https://www.uniprot.org/uniprot/A3KGW5"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Cercam",
            "url": "https://www.uniprot.org/uniprot/A3KGW5",
            "locus": {
                "chromosome": "2",
                "start_pos": 29772852,
                "end_pos": 29759176,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000039787",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000039787"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000039787",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000039787",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "GT25",
            "url": "http://www.cazy.org/GT25.html",
            "database": "CAZy",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd00761",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00761",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd06532",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06532",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "99151",
            "url": "https://www.ncbi.nlm.nih.gov/gene/99151",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR002654",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002654",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR029044",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:99151",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:99151",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "2139134",
            "url": "http://www.informatics.jax.org/marker/MGI:2139134",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "VEVHVCN",
            "url": "https://omabrowser.org/oma/group/VEVHVCN/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5490945at2759",
            "url": "http://www.orthodb.org/?query=5490945at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR10730",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10730",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR10730:SF9",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10730:SF9",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF01755",
            "url": "http://pfam.xfam.org/family/PF01755",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF13704",
            "url": "http://pfam.xfam.org/family/PF13704",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_A3KGW5",
            "url": "http://purl.obolibrary.org/obo/PR_A3KGW5",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_997181",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997181",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A3KGW4",
            "url": "https://www.uniprot.org/uniprot/A3KGW4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A3KGW4-1",
            "url": "https://www.uniprot.org/uniprot/A3KGW4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A3KGW5",
            "url": "https://www.uniprot.org/uniprot/A3KGW5",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A3KGW5-1",
            "url": "https://www.uniprot.org/uniprot/A3KGW5-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A3KGW6",
            "url": "https://www.uniprot.org/uniprot/A3KGW6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A3KGW6-1",
            "url": "https://www.uniprot.org/uniprot/A3KGW6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MHVARLLPLLLLLGQQLRAASVTEPTLPTVVLAILARNAEHSLPHYLGALERLDYPRARLALWCATDHNMDNTTGMLREWLAAVGRDYATVVWKPEEEARSYPDEQGPKHWTKERHQFLMELRQEALAFARDWGADYILFADTDNILTNNQTLKLLIDRQLPVVAPMLDSQTYYSNFWCGITPQGYYRRTAEYFPTKNRQRQGCFRVPMVHSTFLLSLQTEETARLAFYPPHPNYSWPFDDIIVFAYACQAAGVSMHVCNDHRYGYMNVVVKPHQSLEEEKTNFIHLILEALVDGPPMLASAHVSRPPKKLSKMGFDEVFVISLARRPQRRARMLSSLWEMEISAQVVDAVDGRTLNSSILKHLGVDLLPGYQDPYSGHTLTKGEVGCFLSHYSIWEEVVARGLARVVVFEDDVRFKDNFRRRLERLMEDVLIQKLSWDLIYLGRKQVNPEEEVAVEGLPGLVVAGYSYWTLAYTLSLAGARKLLASQPLHRMLPVDEFLPVMFDRHPNDQYKAYFWPRDLQAFSARPLLASPTHYSGDAEWLSDTETSSPWDDDSGRLISQTGSQKALRGPHLHLTGSSGHSLHPHHRDEL",
        "length": 592,
        "header": "sp|A3KGW5-1|GT253_MOUSE Isoform 1 of Inactive glycosyltransferase 25 family member 3  OS=Mus musculus OX=10090 GN=Cercam PE=3 SV=1 CANONICAL=A3KGW5-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A3KGW4-1",
            "url": "",
            "sequence": {
                "sequence": "MAHGSFLPCQRLPRSTRRRRTPGRVWSRCATDHNMDNTTGMLREWLAAVGRDYATVVWKPEEEARSYPDEQGPKHWTKERHQFLMELRQEA",
                "length": 91,
                "header": "tr|A3KGW4-1|A3KGW4_MOUSE Computationally mapped isoform of Cerebral endothelial cell adhesion molecule  OS=Mus musculus OX=10090 GN=Cercam PE=1 SV=8 CANONICAL=A3KGW5-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 29761365,
                "end_pos": 29759275,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000154464.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000154464.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000119476.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000119476.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A3KGW5-1",
            "url": "",
            "sequence": {
                "sequence": "MHVARLLPLLLLLGQQLRAASVTEPTLPTVVLAILARNAEHSLPHYLGALERLDYPRARLALWCATDHNMDNTTGMLREWLAAVGRDYATVVWKPEEEARSYPDEQGPKHWTKERHQFLMELRQEALAFARDWGADYILFADTDNILTNNQTLKLLIDRQLPVVAPMLDSQTYYSNFWCGITPQGYYRRTAEYFPTKNRQRQGCFRVPMVHSTFLLSLQTEETARLAFYPPHPNYSWPFDDIIVFAYACQAAGVSMHVCNDHRYGYMNVVVKPHQSLEEEKTNFIHLILEALVDGPPMLASAHVSRPPKKLSKMGFDEVFVISLARRPQRRARMLSSLWEMEISAQVVDAVDGRTLNSSILKHLGVDLLPGYQDPYSGHTLTKGEVGCFLSHYSIWEEVVARGLARVVVFEDDVRFKDNFRRRLERLMEDVLIQKLSWDLIYLGRKQVNPEEEVAVEGLPGLVVAGYSYWTLAYTLSLAGARKLLASQPLHRMLPVDEFLPVMFDRHPNDQYKAYFWPRDLQAFSARPLLASPTHYSGDAEWLSDTETSSPWDDDSGRLISQTGSQKALRGPHLHLTGSSGHSLHPHHRDEL",
                "length": 592,
                "header": "sp|A3KGW5-1|GT253_MOUSE Isoform 1 of Inactive glycosyltransferase 25 family member 3  OS=Mus musculus OX=10090 GN=Cercam PE=3 SV=1 CANONICAL=A3KGW5-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 29771957,
                "end_pos": 29759550,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000047521",
                        "url": "https://www.ensembl.org/id/ENSMUST00000047521"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000041622",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000041622"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A3KGW6-1",
            "url": "",
            "sequence": {
                "sequence": "VARLLPLLLLLGQQLRAASVTEPTLPTVVLAILARNAEHSLPHYLGALERLDYPRARLALCTMHKIRRTDVKHREAWTLPEATQDILQHLHWSAQLCPIALRTVILCCAHRCATDHNMDNTTGMLREWLAAVGRDYATVVWKPEEEARSYPDEQGPKHW",
                "length": 159,
                "header": "tr|A3KGW6-1|A3KGW6_MOUSE Computationally mapped isoform of Cerebral endothelial cell adhesion molecule  OS=Mus musculus OX=10090 GN=Cercam PE=1 SV=1 CANONICAL=A3KGW5-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 29761320,
                "end_pos": 29759556,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000134152.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000134152.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000115902.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000115902.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 150,
            "start_aa": "Asn",
            "end_pos": 150,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn150",
            "evidence": [
                {
                    "id": "A3KGW5",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/A3KGW5#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 234,
            "start_aa": "Asn",
            "end_pos": 234,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn234",
            "evidence": [
                {
                    "id": "A3KGW5",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/A3KGW5#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 357,
            "start_aa": "Asn",
            "end_pos": 357,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn357",
            "evidence": [
                {
                    "id": "A3KGW5",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/A3KGW5#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 72,
            "start_aa": "Asn",
            "end_pos": 72,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn72",
            "evidence": [
                {
                    "id": "A3KGW5",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/A3KGW5#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "enzyme",
        "glycosyltransferase-activity",
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [],
    "pathway": [
        {
            "id": "mmu:99151",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:99151",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q5T4B2-1",
            "protein_name": "Inactive glycosyltransferase 25 family member 3",
            "gene_name": "CERCAM",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MRAARAAPLLQLLLLLGPWLEAAGVAESPLPAVVLAILARNAEHSLPHYLGALERLDYPRARMALWCATDHNVDNTTEMLQEWLAAVGDDYAAVVWRPEGEPRFYPDEEGPKHWTKERHQFLMELKQEALTFARNWGADYILFADTDNILTNNQTLRLLMGQGLPVVAPMLDSQTYYSNFWCGITPQGYYRRTAEYFPTKNRQRRGCFRVPMVHSTFLASLRAEGADQLAFYPPHPNYTWPFDDIIVFAYACQAAGVSVHVCNEHRYGYMNVPVKSHQGLEDERVNFIHLILEALVDGPRMQASAHVTRPSKRPSKIGFDEVFVISLARRPDRRERMLASLWEMEISGRVVDAVDGWMLNSSAIRNLGVDLLPGYQDPYSGRTLTKGEVGCFLSHYSIWEEVVARGLARVLVFEDDVRFESNFRGRLERLMEDVEAEKLSWDLIYLGRKQVNPEKETAVEGLPGLVVAGYSYWTLAYALRLAGARKLLASQPLRRMLPVDEFLPIMFDQHPNEQYKAHFWPRDLVAFSAQPLLAAPTHYAGDAEWLSDTETSSPWDDDSGRLISWSGSQKTLRSPRLDLTGSSGHSLQPQPRDEL",
                "length": 595
            },
            "evidence": [
                {
                    "id": "45236993",
                    "url": "http://www.informatics.jax.org/homology/45236993",
                    "database": "MGI"
                },
                {
                    "id": "A3KGW5",
                    "url": "https://omabrowser.org/oma/group/A3KGW5/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q5U309-1",
            "protein_name": "Probable inactive glycosyltransferase 25 family member 3",
            "gene_name": "Cercam",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MLFIIRARACGGDARSWKQPDQLHPILFTNLRLPLQLIASSAGGATDHNVDNTTGMLQEWLAAVGRDYATVVWKSEDEARSYPDEQGPKHWTRERHQFLMELKQEALAFARDWGADYILFADTDNILTNNQTLRLLIDRQLPVVAPMLDSQTYYSNFWCGITPQGYYRRTAEYFPTKNRQRQGCFRVPMVHSTFLVSLQTEETARLAFYPPHPNYTWPFDDIIVFAYACQAAGVSVHVCNDHRYGYMNVGVKPHQGLEEEKTNFIHLILEALVDGPPMMASAHVSRPPKKPSKMGFDEVFVISLARRPQRRARMLSSLWEMEISARVVDAVDGRTLNSSILKHLGVDLLPGYQDPYSGRTLTKGEVGCFLSHYSIWEEVVAKGLARVVVFEDDVRFEDNFRKRLERLMEDVLTQKLSWDLIYLGRKQVNPEEEVAVEGLPGLVVAGYSYWTLAYTLSLAGARKLLASQPLHRMLPVDEFLPVMFDRHPNDQYKAHFWPRDLQAFSARPLLASPTHYAGDTEWLSDTETSSPWDDDSGRLISWTGSQKTLRGPYLHLAGSSGHSLHPHPRDEL",
                "length": 572
            },
            "evidence": [
                {
                    "id": "45236993",
                    "url": "http://www.informatics.jax.org/homology/45236993",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "endoplasmic reticulum lumen",
                        "id": "GO:0005788",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A3KGW5",
                                "url": "https://www.uniprot.org/uniprot/A3KGW5"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 1,
                "go_terms": [
                    {
                        "name": "cell adhesion",
                        "id": "GO:0007155",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A3KGW5",
                                "url": "https://www.uniprot.org/uniprot/A3KGW5"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "identical protein binding",
                        "id": "GO:0042802",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802",
                        "evidence": [
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