{ "uniprot_canonical_ac": "A2ANX3-1", "uniprot_ac": "A2ANX3", "uniprot_id": "A2ANX3_MOUSE", "mass": { "chemical_mass": 135143.0, "monoisotopic_mass": 135143.0 }, "refseq": { "ac": "NP_001074413", "name": "probable phospholipid-transporting ATPase IM", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074413" }, "gene_names": [ { "name": "Atp8b4", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A2ANX3", "id": "A2ANX3" }, { "name": "Atp8b4", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074413", "id": "NP_001074413" }, { "name": "Im", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074413", "id": "NP_001074413" } ], "protein_names": [ { "name": "Phospholipid-transporting ATPase", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "A2ANX3" }, { "name": "7.6.2.1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A2ANX3" }, { "name": "ATPase 8B4, p type; ATPase B4, class I", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074413", "id": "NP_001074413" }, { "name": "probable phospholipid-transporting ATPase IM", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074413", "id": "NP_001074413" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2ANX3", "url": "https://www.uniprot.org/uniprot/A2ANX3" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Atp8b4", "url": "https://www.uniprot.org/uniprot/A2ANX3", "locus": { "chromosome": "2", "start_pos": 126162893, "end_pos": 126342594, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000060131", "url": "https://www.ensembl.org/id/ENSMUSG00000060131" } ] } } ], "crossref": [ { "id": "ENSMUSG00000060131", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000060131", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02073", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02073", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "241633", "url": "https://www.ncbi.nlm.nih.gov/gene/241633", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006539", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006539", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008250", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008250", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023298", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023298", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032631", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032631", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:241633", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:241633", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "1859664", "url": "http://www.informatics.jax.org/marker/MGI:1859664", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "KHSILSV", "url": "https://omabrowser.org/oma/group/KHSILSV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "275833at2759", "url": "http://www.orthodb.org/?query=275833at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24092", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24092", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24092:SF80", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24092:SF80", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13246", "url": "http://pfam.xfam.org/family/PF13246", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF16209", "url": "http://pfam.xfam.org/family/PF16209", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF16212", "url": "http://pfam.xfam.org/family/PF16212", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6798695", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-936837", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-936837", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_001074413", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074413", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2ANX2", "url": "https://www.uniprot.org/uniprot/A2ANX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2ANX2-1", "url": "https://www.uniprot.org/uniprot/A2ANX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2ANX3", "url": "https://www.uniprot.org/uniprot/A2ANX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2ANX3-1", "url": "https://www.uniprot.org/uniprot/A2ANX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z411", "url": "https://www.uniprot.org/uniprot/F2Z411", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z411-1", "url": "https://www.uniprot.org/uniprot/F2Z411-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMFCNKKKLLEVERVVKANDRDYNEKFQYADNRIHTSKYNVLTFLPINLFEQLQRVANAYFLFLLILQLIPEISSLTWFTTIVPLVLVISMTAVKDATDDYFRHKSDNQVNNRQSKVLINSKLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRQALPVTSELGADISSLAEFDGIVRCEAPNNKLDRFSGVLSWKDSKHALSNQKIILRGCVLRNTSWCFGMVLFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLVCLGIILAVGSSILESEVGDQFRTPPFWREGEKSFLFSGFLTFWSYVIILNTLVPISLYVSVEVIRLGHSYFINWDRKMYYASKAMPAEARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKKCSINGRVYAGEVLDDPIQKKEITKEKEATDFSSKSKSEKTLHFFDQSLMESIELGDPKVHEFLRLLALCHTVMSEENSAGQLVYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTPVTYQLLAFLDFNNIRKRMSVIVRNPEGRIKLYSKGADTILFEKLHPSNEDLQSLTSDHLSEFAGEGLRTLAIAYRELDDKYFKMWQKMLEDANSATLERDERISGLYEEIERDLMLLGATAVEDKLQEGVIETITSLSLANIKIWILTGDKQETAINIGYACNVLTDAMDALFVITGNTAGEVREELRKAKENLLGQSTSFSNGHAVYDNKQRLGLDAGAGEAVTGEYALVINGHSLAHALESDVENDLLELACVCKTVVCCRVTPLQKAQVVELVKKHRNAVTLAIGDGANDVSMIKSAHIGIGISGQEGLQAVLASDYALAQFRYLQRLLLVHGRWSYYRMCKFLCYFFYKNFAFTLVHFWFAFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGMFDQDINEQNSMDYPQLYEPGQLNLLFNKRRFFICVAHGIYTSLALFFIPYGAFYNVAAEDGQHIADLQSFAVTVATSLVIVVSIQIALDTSYWTVVNHVFIWGSVATYFSILLAMHSDGVFGIFPRHFPFVGNARHSLSQKFVWLVVLLTAVTSVMPVVVVRFLKMYLYPSLSDQIRRWQKAQRKKRPLRSRRPQTRRSSSRRSGYAFAHQEGYGELITSGKNMRAKSPAPASGLEKKLYNNTSWIENLCKKTTDAVSGFSHDKTVKL", "length": 1194, "header": "tr|A2ANX3-1|A2ANX3_MOUSE Isoform 1 of Phospholipid-transporting ATPase OS=Mus musculus OX=10090 GN=Atp8b4 PE=1 SV=1 CANONICAL=A2ANX3-1" }, "isoforms": [ { "isoform_ac": "A2ANX2-1", "url": "", "sequence": { "sequence": "MMFCNKKKLLEVERVVKANDRDYNEKFQYADNRIHTSKYNVLTFLPINLFEQLQRVANAYFLFLLILQLIPEISSLTWFTTIVPLVLVISMTAVKDATDDYFRHKSDNQVNNRQSKVLINSKLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRQALPVTSELGADISSLAEFDGIVRCEAPNNKLDRFSGVLSWKDSKHALSNQKIILRGCVLRNTSWCFGMVLFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLVCLGIILAVGSSILESEVGDQFRTPPFWREGEKSFLFSGFLTFWSYVIILNTLVPISLYVSVEVIRLGHSYFINWDRKMYYASKAMPAEARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKKCSINGRVYAGEVLDDPIQK", "length": 426, "header": "tr|A2ANX2-1|A2ANX2_MOUSE Computationally mapped isoform of Phospholipid-transporting ATPase OS=Mus musculus OX=10090 GN=Atp8b4 PE=1 SV=1 CANONICAL=A2ANX3-1" }, "locus": { "chromosome": "2", "start_pos": 126331330, "end_pos": 126234737, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000129187.2", "url": "https://www.ensembl.org/id/ENSMUST00000129187.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000118651.2", "url": "https://www.ensembl.org/id/ENSMUSP00000118651.2" } ] } }, { "isoform_ac": "A2ANX3-1", "url": "", "sequence": { "sequence": "MMFCNKKKLLEVERVVKANDRDYNEKFQYADNRIHTSKYNVLTFLPINLFEQLQRVANAYFLFLLILQLIPEISSLTWFTTIVPLVLVISMTAVKDATDDYFRHKSDNQVNNRQSKVLINSKLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRQALPVTSELGADISSLAEFDGIVRCEAPNNKLDRFSGVLSWKDSKHALSNQKIILRGCVLRNTSWCFGMVLFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLVCLGIILAVGSSILESEVGDQFRTPPFWREGEKSFLFSGFLTFWSYVIILNTLVPISLYVSVEVIRLGHSYFINWDRKMYYASKAMPAEARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKKCSINGRVYAGEVLDDPIQKKEITKEKEATDFSSKSKSEKTLHFFDQSLMESIELGDPKVHEFLRLLALCHTVMSEENSAGQLVYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTPVTYQLLAFLDFNNIRKRMSVIVRNPEGRIKLYSKGADTILFEKLHPSNEDLQSLTSDHLSEFAGEGLRTLAIAYRELDDKYFKMWQKMLEDANSATLERDERISGLYEEIERDLMLLGATAVEDKLQEGVIETITSLSLANIKIWILTGDKQETAINIGYACNVLTDAMDALFVITGNTAGEVREELRKAKENLLGQSTSFSNGHAVYDNKQRLGLDAGAGEAVTGEYALVINGHSLAHALESDVENDLLELACVCKTVVCCRVTPLQKAQVVELVKKHRNAVTLAIGDGANDVSMIKSAHIGIGISGQEGLQAVLASDYALAQFRYLQRLLLVHGRWSYYRMCKFLCYFFYKNFAFTLVHFWFAFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGMFDQDINEQNSMDYPQLYEPGQLNLLFNKRRFFICVAHGIYTSLALFFIPYGAFYNVAAEDGQHIADLQSFAVTVATSLVIVVSIQIALDTSYWTVVNHVFIWGSVATYFSILLAMHSDGVFGIFPRHFPFVGNARHSLSQKFVWLVVLLTAVTSVMPVVVVRFLKMYLYPSLSDQIRRWQKAQRKKRPLRSRRPQTRRSSSRRSGYAFAHQEGYGELITSGKNMRAKSPAPASGLEKKLYNNTSWIENLCKKTTDAVSGFSHDKTVKL", "length": 1194, "header": "tr|A2ANX3-1|A2ANX3_MOUSE Isoform 1 of Phospholipid-transporting ATPase OS=Mus musculus OX=10090 GN=Atp8b4 PE=1 SV=1 CANONICAL=A2ANX3-1" }, "locus": { "chromosome": "2", "start_pos": 126331330, "end_pos": 126164733, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000040149.13", "url": "https://www.ensembl.org/id/ENSMUST00000040149.13" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000047302.7", "url": "https://www.ensembl.org/id/ENSMUSP00000047302.7" } ] } }, { "isoform_ac": "F2Z411-1", "url": "", "sequence": { "sequence": "MMFCNKKKLLEVERVVKANDRDYNEKFQYADNRIHTSKYNVLTFLPINLFEQLQRVANAYFLFLLILQLIPEISSLTWFTTIVPLVLVISMTAVKDATDDYFRHKSDNQVNNRQSKVLINSKLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRQALPVTSELGADISSLAEFDGIVRCEAPNNKLDRFSGVLSWKDSKHALSNQKIILRGCVLRNTSWCFGMVLFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLVCLGIILAVGSSILESEVGDQFRTPPFWREGEKSFLFSGFLTFWSYVIILNTLVPISLYVSVEVIRLGHSYFINWDRKMYYASKAMPAEARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKKCSINGRVYGKGGYGLLKQVEIRKNTAFL", "length": 435, "header": "tr|F2Z411-1|F2Z411_MOUSE Computationally mapped isoform of Phospholipid-transporting ATPase OS=Mus musculus OX=10090 GN=Atp8b4 PE=1 SV=1 CANONICAL=A2ANX3-1" }, "locus": { "chromosome": "2", "start_pos": 126331330, "end_pos": 126231268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000147517.8", "url": "https://www.ensembl.org/id/ENSMUST00000147517.8" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000114252.2", "url": "https://www.ensembl.org/id/ENSMUSP00000114252.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "A2ANX3", "url": "https://www.uniprot.org/uniprot/A2ANX3" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "pathway": [ { "id": "mmu:241633", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:241633", "resource": "KEGG Pathway" }, { "id": "R-MMU-6798695", "name": "Neutrophil degranulation", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-MMU-936837", "name": "Ion transport by P-type ATPases", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-936837", "resource": "Reactome", "description": "Ion transport by P-type ATPases" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8TF62-1", "protein_name": "Probable phospholipid-transporting ATPase IM", "gene_name": "ATP8B4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFCSEKKLREVERIVKANDREYNEKFQYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTGDQFRTFLFWNEGEKSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVKSQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSNGHVVCEKKQQLELDSIVEETITGDYALIINGHSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQIRRWQKAQKKARPPSSRRPRTRRSSSRRSGYAFAHQEGYGELITSGKNMRAKNPPPTSGLEKTHYNSTSWIENLCKKTTDTVSSFSQDKTVKL", "length": 1192 }, "evidence": [ { "id": "45235085", "url": "http://www.informatics.jax.org/homology/45235085", "database": "MGI" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A2ANX3", "url": "https://www.uniprot.org/uniprot/A2ANX3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A2ANX3", "url": "https://www.uniprot.org/uniprot/A2ANX3" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A2ANX3", "url": "https://www.uniprot.org/uniprot/A2ANX3" } ], "pmid": "" }, { "name": "ATPase-coupled intramembrane lipid transporter activity", "id": "GO:0140326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140326", "evidence": [ { "database": "UniProtKB", "id": "A2ANX3", "url": "https://www.uniprot.org/uniprot/A2ANX3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A2ANX3", "url": "https://www.uniprot.org/uniprot/A2ANX3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A2ANX3", "url": "https://www.uniprot.org/uniprot/A2ANX3" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A2ANX3", "url": "https://www.uniprot.org/uniprot/A2ANX3" } ], "pmid": "" }, { "name": "phospholipid-translocating ATPase complex", "id": "GO:1990531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990531", "evidence": [ { "database": "UniProtKB", "id": "A2ANX3", "url": "https://www.uniprot.org/uniprot/A2ANX3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phospholipid translocation", "id": "GO:0045332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045332", "evidence": [ { "database": "UniProtKB", "id": "A2ANX3", "url": "https://www.uniprot.org/uniprot/A2ANX3" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A2ANX3", "url": "https://www.uniprot.org/uniprot/A2ANX3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1167, "end_pos": 1169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1168, "end_pos": 1170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-MMU-6798747", "name": "Exocytosis of tertiary granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, tertiary granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P70699-1", "Q9Z280-1", "O35598-1", "P62482-1", "B2RU80-1", "Q8BU31-1", "A2AN08-1", "P98197-1", "Q61093-1", "Q3UDW8-1", "P08556-1", "P61226-1", "Q05910-1", "P06869-1", "A2ANX3-1" ], "evidence": [ { "id": "R-MMU-6798747", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6798747" } ] }, { "id": "R-MMU-6799350", "name": "Exocytosis of specific granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, specific granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q64455-1", "O09005-1", "Q9Z280-1", "O35598-1", "P70704-1", "P62482-1", "B2RU80-1", "Q9Z2A7-1", "O35488-1", "A2AN08-1", "P98197-1", "Q61093-1", "O70252-1", "Q3UDW8-1", "Q80VQ0-1", "Q64277-1", "Q8K3K7-1", "Q3U435-1", "P62835-1", "O55098-1", "P61226-1", "Q05910-1", "P06869-1", "A2ANX3-1" ], "evidence": [ { "id": "R-MMU-6799350", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6799350" } ] }, { "id": "R-MMU-939763", "name": "P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O54827-1", "Q6UQ17-1", "P70704-1", "P98200-1", "Q148W0-1", "O70228-1", "P98195-1", "P98197-1", "Q8K2X1-1", "P98199-1", "Q9QZW0-1", "B1AWN4-1", "A2ANX3-1", "Q6DFW5-1" ], "evidence": [ { "id": "R-MMU-939763", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-939763" } ] }, { "id": "R-MMU-947591", "name": "P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O54827-1", "Q6UQ17-1", "P70704-1", "P98200-1", "Q148W0-1", "O70228-1", "P98195-1", "P98197-1", "Q8K2X1-1", "P98199-1", "Q9QZW0-1", "B1AWN4-1", "A2ANX3-1", "Q6DFW5-1" ], "evidence": [ { "id": "R-MMU-947591", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-947591" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A2AN08", "gene_name": "Ubr4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A2AN08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AN08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A2AN08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2AN08" } ] } ] }, { "uniprot_ac": "A2ANX3", "gene_name": "Atp8b4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A2ANX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2ANX3" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A2ANX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A2ANX3" } ] } ] }, { "uniprot_ac": "B1AWN4", "gene_name": "Atp10b", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "B1AWN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1AWN4" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "B1AWN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B1AWN4" } ] } ] }, { "uniprot_ac": "B2RU80", "gene_name": "Ptprb", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "B2RU80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RU80" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "B2RU80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/B2RU80" } ] } ] }, { "uniprot_ac": "O09005", "gene_name": "Degs1", "activity": [ { "ec_number": "1.14.19.17", "activity": "an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = an N-acylsphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O.", "evidence": [ { "id": "O09005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09005" } ] }, { "ec_number": "5.2.1.-", "activity": "", "evidence": [ { "id": "O09005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09005" } ] }, { "ec_number": "1.14.19.17", "activity": "", "evidence": [ { "id": "O09005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O09005" } ] } ] }, { "uniprot_ac": "O35488", "gene_name": "Slc27a2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "O35488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35488" } ] }, { "ec_number": "6.2.1.-", "activity": "", "evidence": [ { "id": "O35488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35488" } ] }, { "ec_number": "6.2.1.7", "activity": "(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + ATP + CoA = (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "O35488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35488" } ] }, { "ec_number": "6.2.1.24", "activity": "3,7,11,15-tetramethylhexadecanoate + ATP + CoA = AMP + diphosphate + phytanoyl-CoA.", "evidence": [ { "id": "O35488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35488" } ] }, { "ec_number": "6.2.1.15", "activity": "(5Z,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "O35488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35488" } ] } ] }, { "uniprot_ac": "O35598", "gene_name": "Adam10", "activity": [ { "ec_number": "3.4.24.81", "activity": "Endopeptidase of broad specificity.", "evidence": [ { "id": "O35598", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35598" } ] }, { "ec_number": "3.4.24.81", "activity": "", "evidence": [ { "id": "O35598", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O35598" } ] } ] }, { "uniprot_ac": "O54827", "gene_name": "Atp10a", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "O54827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54827" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "O54827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O54827" } ] } ] }, { "uniprot_ac": "O55098", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein].", "evidence": [ { "id": "O55098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55098" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O55098", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O55098" } ] } ] }, { "uniprot_ac": "O70228", "gene_name": "Atp9a", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "O70228", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70228" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "O70228", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70228" } ] } ] }, { "uniprot_ac": "O70252", "gene_name": "Hmox2", "activity": [ { "ec_number": "1.14.14.18", "activity": "heme b + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = biliverdin IXalpha + CO + Fe(2+) + H(+) + 3 H2O + 3 oxidized [NADPH--hemoprotein reductase].", "evidence": [ { "id": "O70252", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70252" } ] }, { "ec_number": "1.14.14.18", "activity": "", "evidence": [ { "id": "O70252", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/O70252" } ] } ] }, { "uniprot_ac": "P06869", "gene_name": "Plau", "activity": [ { "ec_number": "3.4.21.73", "activity": "Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin.", "evidence": [ { "id": "P06869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06869" } ] }, { "ec_number": "3.4.21.73", "activity": "", "evidence": [ { "id": "P06869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P06869" } ] } ] }, { "uniprot_ac": "P08556", "gene_name": "Nras", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + H(+) + phosphate.", "evidence": [ { "id": "P08556", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08556" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P08556", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P08556" } ] } ] }, { "uniprot_ac": "P61226", "gene_name": "Rap2b", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + H(+) + phosphate.", "evidence": [ { "id": "P61226", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P61226" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P61226", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P61226" } ] } ] }, { "uniprot_ac": "P62482", "gene_name": "Kcnab2", "activity": [ { "ec_number": "1.1.1.-", "activity": "", "evidence": [ { "id": "P62482", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62482" } ] } ] }, { "uniprot_ac": "P62835", "gene_name": "Rap1a", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + H(+) + phosphate.", "evidence": [ { "id": "P62835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62835" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P62835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P62835" } ] } ] }, { "uniprot_ac": "P70699", "gene_name": "Gaa", "activity": [ { "ec_number": "3.2.1.20", "activity": "Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.", "evidence": [ { "id": "P70699", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70699" } ] }, { "ec_number": "3.2.1.20", "activity": "", "evidence": [ { "id": "P70699", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70699" } ] } ] }, { "uniprot_ac": "P70704", "gene_name": "Atp8a1", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "P70704", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70704" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "P70704", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P70704" } ] } ] }, { "uniprot_ac": "P98195", "gene_name": "Atp9b", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "P98195", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P98195" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "P98195", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P98195" } ] } ] }, { "uniprot_ac": "P98197", "gene_name": "Atp11a", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "P98197", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P98197" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "P98197", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P98197" } ] } ] }, { "uniprot_ac": "P98199", "gene_name": "Atp8b2", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "P98199", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P98199" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "P98199", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P98199" } ] } ] }, { "uniprot_ac": "P98200", "gene_name": "Atp8a2", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "P98200", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P98200" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "P98200", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/P98200" } ] } ] }, { "uniprot_ac": "Q05910", "gene_name": "Adam8", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q05910", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q05910" } ] } ] }, { "uniprot_ac": "Q148W0", "gene_name": "Atp8b1", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "Q148W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q148W0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "Q148W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q148W0" } ] } ] }, { "uniprot_ac": "Q3U435", "gene_name": "Mmp25", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q3U435", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3U435" } ] } ] }, { "uniprot_ac": "Q3UDW8", "gene_name": "Hgsnat", "activity": [ { "ec_number": "2.3.1.78", "activity": "acetyl-CoA + alpha-D-glucosaminyl-[heparan sulfate](n) = CoA + H(+) + N-acetyl-alpha-D-glucosaminyl-[heparan sulfate](n).", "evidence": [ { "id": "Q3UDW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UDW8" } ] }, { "ec_number": "2.3.1.78", "activity": "", "evidence": [ { "id": "Q3UDW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q3UDW8" } ] } ] }, { "uniprot_ac": "Q61093", "gene_name": "Cybb", "activity": [ { "ec_number": "1.-.-.-", "activity": "", "evidence": [ { "id": "Q61093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q61093" } ] } ] }, { "uniprot_ac": "Q64277", "gene_name": "Bst1", "activity": [ { "ec_number": "3.2.2.6", "activity": "H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide.", "evidence": [ { "id": "Q64277", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64277" } ] }, { "ec_number": "3.2.2.6", "activity": "", "evidence": [ { "id": "Q64277", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64277" } ] } ] }, { "uniprot_ac": "Q64455", "gene_name": "Ptprj", "activity": [ { "ec_number": "3.1.3.48", "activity": "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q64455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q64455" } ] } ] }, { "uniprot_ac": "Q6DFW5", "gene_name": "Atp11b", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "Q6DFW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6DFW5" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "Q6DFW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6DFW5" } ] } ] }, { "uniprot_ac": "Q6UQ17", "gene_name": "Atp8b3", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "Q6UQ17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6UQ17" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "Q6UQ17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q6UQ17" } ] } ] }, { "uniprot_ac": "Q80VQ0", "gene_name": "Aldh3b1", "activity": [ { "ec_number": "1.2.1.5", "activity": "an aldehyde + H2O + NAD(+) = a carboxylate + 2 H(+) + NADH.", "evidence": [ { "id": "Q80VQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80VQ0" } ] }, { "ec_number": "1.2.1.28", "activity": "benzaldehyde + H2O + NAD(+) = benzoate + 2 H(+) + NADH.", "evidence": [ { "id": "Q80VQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80VQ0" } ] }, { "ec_number": "1.2.1.7", "activity": "benzaldehyde + H2O + NADP(+) = benzoate + 2 H(+) + NADPH.", "evidence": [ { "id": "Q80VQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80VQ0" } ] }, { "ec_number": "1.2.1.7", "activity": "", "evidence": [ { "id": "Q80VQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80VQ0" } ] }, { "ec_number": "1.2.1.5", "activity": "", "evidence": [ { "id": "Q80VQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80VQ0" } ] }, { "ec_number": "1.2.1.28", "activity": "", "evidence": [ { "id": "Q80VQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q80VQ0" } ] } ] }, { "uniprot_ac": "Q8BU31", "gene_name": "Rap2c", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + H(+) + phosphate.", "evidence": [ { "id": 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