{ "uniprot_canonical_ac": "A2AJA9-1", "uniprot_ac": "A2AJA9", "uniprot_id": "AJM1_MOUSE", "mass": { "chemical_mass": 107186.0, "monoisotopic_mass": 107186.0 }, "refseq": { "ac": "NP_001005424", "name": "apical junction component 1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005424" }, "gene_names": [ { "name": "Ajm1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A2AJA9", "id": "A2AJA9" }, { "name": "Ajm1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005424", "id": "NP_001005424" }, { "name": "Gm996", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005424", "id": "NP_001005424" }, { "name": "Gm996", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2AJA9", "id": "A2AJA9" } ], "protein_names": [ { "name": "Apical junction component 1 homolog", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "A2AJA9" }, { "name": "Uncharacterized protein C9orf172 homolog", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005424", "id": "NP_001005424" }, { "name": "apical junction component 1 homolog", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005424", "id": "NP_001005424" } ], "function": [ { "annotation": "May be involved in the control of adherens junction integrity.", "evidence": [ { "database": "UniProtKB", "id": "A2AJA9", "url": "https://www.uniprot.org/uniprot/A2AJA9#function" }, { "database": "UniProtKB", "id": "A0A1C3NSL9", "url": "https://www.uniprot.org/uniprot/A0A1C3NSL9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AJA9", "url": "https://www.uniprot.org/uniprot/A2AJA9" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Ajm1", "url": "https://www.uniprot.org/uniprot/A2AJA9", "locus": { "chromosome": "2", "start_pos": 25465428, "end_pos": 25471769, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000029419", "url": "https://www.ensembl.org/id/ENSMUSG00000029419" } ] } } ], "crossref": [ { "id": "ENSMUSG00000029419", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000029419", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "381353", "url": "https://www.ncbi.nlm.nih.gov/gene/381353", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "A2AJA9", "url": "https://www.ebi.ac.uk/intact/interactors/id:A2AJA9*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR038825", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038825", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:381353", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:381353", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "2685842", "url": "http://www.informatics.jax.org/marker/MGI:2685842", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "A2AJA9", "url": "https://oglcnac.org/atlas/detail/A2AJA9", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "A2AJA9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A2AJA9", "database": "O-GlcNAc Database", "categories": [ "Glycoproteomics" ] }, { "id": "KEKTHDN", "url": "https://omabrowser.org/oma/group/KEKTHDN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "1561748at2759", "url": "http://www.orthodb.org/?query=1561748at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21517", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21517", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21517:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21517:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PR_A2AJA9", "url": "http://purl.obolibrary.org/obo/PR_A2AJA9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001005424", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005424", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A087WP25", "url": "https://www.uniprot.org/uniprot/A0A087WP25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WP25-1", "url": "https://www.uniprot.org/uniprot/A0A087WP25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2AJA9", "url": "https://www.uniprot.org/uniprot/A2AJA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2AJA9-1", "url": "https://www.uniprot.org/uniprot/A2AJA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2AJA9-2", "url": "https://www.uniprot.org/uniprot/A2AJA9-2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRTDPPDLLVSTVYQDIKVVDPGLTSKRQPCERSVARPAAPTPFNKRHCRSFDFLEALDEPTMETHPEPPPPEPAPPRARPRDSEPRRRTRSKSAPRASQGLATAPASPPVLQRRGREAQRAVRVEGSPRREPSYPALRALANELHPIKLQPQRGGPGRIAPLCATPGRCAPPEPPSGPVPHVRCRLDIKPDEAVLQHAARSSRSCAPRETTSWARTAPQFHGLTVPGPRHVALSRTPTPSDLYCTDPRTLYCDGPLPGPRDYLEHRSQPFTTPPGPTQFFYTEEPEGYAGSFTTSPGLPFDGYCSRPYLSEEPPRPSPRRGGSYYAGEVRTFPIQEPPSRSYYGETTRAYGMPFVPRYVPEEPRAHPGARTFYTEDFGRYRERDVLARTYPHPRSSPPWADWGPRPYRTLQVMPPPAPGPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVRDTRGSSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRAGESLGRNWYVTPEITITDNDLRSVDRPTAKGWELPGGRPRQPVSTVPEGPASSRQRSLEQLDELITDLVIDSRSPAQAPEPAAEGLGRQLRRLLDSRAAGPGGATLLAPSRSPPASAGSTEEPTGSGEAADASPEPSADEDDLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCRHVLQFCRDSSPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYLSLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPSAAPPGAAARPAPRTPGPTVRKFAKVALAAGSPTRPPPARGGEPDMETLILTPPPGTAGLDEEGEAGRRAREVAFIHIQRELRMRGVFLRHEFPRVYEQLCEFVEANRRFTPTTIYPTDRRTGRPFMCMIMAASEPRALDWVASANLLDDIM", "length": 974, "header": "sp|A2AJA9-1|AJM1_MOUSE Isoform 1 of Apical junction component 1 homolog OS=Mus musculus OX=10090 GN=Ajm1 PE=1 SV=1 CANONICAL=A2AJA9-1" }, "isoforms": [ { "isoform_ac": "A0A087WP25-1", "url": "", "sequence": { "sequence": "MTRTDPPDLLVSTVYQDIKVVDPGLTSKR", "length": 29, "header": "tr|A0A087WP25-1|AJM1_MOUSE Computationally mapped isoform of Apical junction component 1 homolog OS=Mus musculus OX=10090 GN=Ajm1 PE=1 SV=1 CANONICAL=A2AJA9-1" }, "locus": { "chromosome": "2", "start_pos": 25469909, "end_pos": 25469823, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000187017.2", "url": "https://www.ensembl.org/id/ENSMUST00000187017.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000139598.2", "url": "https://www.ensembl.org/id/ENSMUSP00000139598.2" } ] } }, { "isoform_ac": "A2AJA9-1", "url": "", "sequence": { "sequence": "MTRTDPPDLLVSTVYQDIKVVDPGLTSKRQPCERSVARPAAPTPFNKRHCRSFDFLEALDEPTMETHPEPPPPEPAPPRARPRDSEPRRRTRSKSAPRASQGLATAPASPPVLQRRGREAQRAVRVEGSPRREPSYPALRALANELHPIKLQPQRGGPGRIAPLCATPGRCAPPEPPSGPVPHVRCRLDIKPDEAVLQHAARSSRSCAPRETTSWARTAPQFHGLTVPGPRHVALSRTPTPSDLYCTDPRTLYCDGPLPGPRDYLEHRSQPFTTPPGPTQFFYTEEPEGYAGSFTTSPGLPFDGYCSRPYLSEEPPRPSPRRGGSYYAGEVRTFPIQEPPSRSYYGETTRAYGMPFVPRYVPEEPRAHPGARTFYTEDFGRYRERDVLARTYPHPRSSPPWADWGPRPYRTLQVMPPPAPGPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVRDTRGSSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRAGESLGRNWYVTPEITITDNDLRSVDRPTAKGWELPGGRPRQPVSTVPEGPASSRQRSLEQLDELITDLVIDSRSPAQAPEPAAEGLGRQLRRLLDSRAAGPGGATLLAPSRSPPASAGSTEEPTGSGEAADASPEPSADEDDLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCRHVLQFCRDSSPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYLSLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPSAAPPGAAARPAPRTPGPTVRKFAKVALAAGSPTRPPPARGGEPDMETLILTPPPGTAGLDEEGEAGRRAREVAFIHIQRELRMRGVFLRHEFPRVYEQLCEFVEANRRFTPTTIYPTDRRTGRPFMCMIMAASEPRALDWVASANLLDDIM", "length": 974, "header": "sp|A2AJA9-1|AJM1_MOUSE Isoform 1 of Apical junction component 1 homolog OS=Mus musculus OX=10090 GN=Ajm1 PE=1 SV=1 CANONICAL=A2AJA9-1" }, "locus": { "chromosome": "2", "start_pos": 25469909, "end_pos": 25466988, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000114217", "url": "https://www.ensembl.org/id/ENSMUST00000114217" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000109855", "url": "https://www.ensembl.org/id/ENSMUSP00000109855" } ] } }, { "isoform_ac": "A2AJA9-2", "url": "", "sequence": { "sequence": "MTRTDPPDLLVSTVYQDIKVVDPGLTSKRQPCERSVARPAAPTPFNKRHCRSFDFLEALDEPTMETHPEPPPPEPAPPRARPRDSEPRRRTRSKSAPRASQGLATAPASPPVLQRRGREAQRAVRVEGSPRREPSYPALRALANELHPIKLQPQRGGPGRIAPLCATPGRCAPPEPPSGPVPHVRCRLDIKPDEAVLQHAALSRTPTPSDLYCTDPRTLYCDGPLPGPRDYLEHRSQPFTTPPGPTQFFYTEEPEGYAGSFTTSPGLPFDGYCSRPYLSEEPPRPSPRRGGSYYAGEVRTFPIQEPPSRSYYGETTRAYGMPFVPRYVPEEPRAHPGARTFYTEDFGRYRERDVLARTYPHPRSSPPWADWGPRPYRTLQVMPPPAPGPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVRDTRGSSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRAGESLGRNWYVTPEITITDNDLRSVDRPTAKGWELPGGRPRQPVSTVPEGPASSRQRSLEQLDELITDLVIDSRSPAQAPEPAAEGLGRQLRRLLDSRAAGPGGATLLAPSRSPPASAGSTEEPTGSGEAADASPEPSADEDDLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCRHVLQFCRDSSPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYLSLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPSAAPPGAAARPAPRTPGPTVRKFAKVALAAGSPTRPPPARGGEPDMETLILTPPPGTAGLDEEGEAGRRAREVAFIHIQRELRMRGVFLRHEFPRVYEQLCEFVEANRRFTPTTIYPTDRRTGRPFMCMIMAASEPRALDWVASANLLDDIM", "length": 941, "header": "sp|A2AJA9-2|AJM1_MOUSE Isoform 2 of Apical junction component 1 homolog OS=Mus musculus OX=10090 GN=Ajm1 PE=1 SV=1 CANONICAL=A2AJA9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 497, "start_aa": "Ser", "end_pos": 497, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser497", "evidence": [ { "id": "A2AJA9", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/A2AJA9" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 564, "start_aa": "Thr", "end_pos": 564, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr564", "evidence": [ { "id": "A2AJA9", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/A2AJA9" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 935, "start_aa": "Thr", "end_pos": 935, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr935", "evidence": [ { "id": "A2AJA9", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/A2AJA9" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 936, "start_aa": "Thr", "end_pos": 936, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr936", "evidence": [ { "id": "A2AJA9", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/A2AJA9" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "evidence": [ { "id": "A2AJA9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A2AJA9" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "phosphorylation": [ { "start_pos": 129, "end_pos": 129, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AJA9", "url": "https://www.uniprot.org/uniprot/A2AJA9" }, { "database": "PubMed", "id": "16452087", "url": "https://glygen.org/publication/PubMed/16452087" }, { "database": "iPTMnet", "id": "A2AJA9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AJA9" } ], "site_lbl": "Ser129" }, { "start_pos": 468, "end_pos": 468, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AJA9", "url": "https://www.uniprot.org/uniprot/A2AJA9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2AJA9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AJA9" } ], "site_lbl": "Ser468" }, { "start_pos": 509, "end_pos": 509, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AJA9", "url": "https://www.uniprot.org/uniprot/A2AJA9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2AJA9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AJA9" } ], "site_lbl": "Ser509" }, { "start_pos": 512, "end_pos": 512, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AJA9", "url": "https://www.uniprot.org/uniprot/A2AJA9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2AJA9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AJA9" } ], "site_lbl": "Ser512" }, { "start_pos": 52, "end_pos": 52, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AJA9", "url": "https://www.uniprot.org/uniprot/A2AJA9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2AJA9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AJA9" } ], "site_lbl": "Ser52" }, { "start_pos": 593, "end_pos": 593, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AJA9", "url": "https://www.uniprot.org/uniprot/A2AJA9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "A2AJA9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AJA9" } ], "site_lbl": "Ser593" } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Comprehensive identification of phosphorylation sites in postsynaptic density preparations.", "journal": "Molecular & cellular proteomics : MCP", "date": "2006", "authors": "Trinidad JC, Specht CG, Thalhammer A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "UniProtKB", "id": "A2AJA9", "url": "https://www.uniprot.org/uniprot/A2AJA9" }, { "database": "iPTMnet", "id": "A2AJA9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AJA9" } ], "reference": [ { "type": "PubMed", "id": "16452087", "url": "https://glygen.org/publication/PubMed/16452087" } ] }, { "title": "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.", "journal": "Mol. Cell. Proteomics", "date": "2007", "authors": "Munton RP, Tweedie-Cullen R, Livingstone-Zatchej M, Weinandy F, Waidelich M, Longo D, Gehrig P, Potthast F, Rutishauser D, Gerrits B, Panse C, Schlapbach R, Mansuy IM", "evidence": [ { "database": "UniProtKB", "id": "A2AJA9", "url": "https://www.uniprot.org/uniprot/A2AJA9" } ], "reference": [ { "type": "PubMed", "id": "17114649", "url": "https://glygen.org/publication/PubMed/17114649" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2AJA9", "url": "https://www.uniprot.org/uniprot/A2AJA9" }, { "database": "iPTMnet", "id": "A2AJA9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AJA9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "A2AJA9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A2AJA9" }, { "database": "O-GlcNAc Atlas", "id": "A2AJA9", "url": "https://oglcnac.org/atlas/detail/A2AJA9" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.", "journal": "Mol. Cell. Proteomics", "date": "2014", "authors": "Guo A, Gu H, Zhou J, Mulhern D, Wang Y, Lee KA, Yang V, Aguiar M, Kornhauser J, Jia X, Ren J, Beausoleil SA, Silva JC, Vemulapalli V, Bedford MT, Comb MJ", "evidence": [ { "database": "UniProtKB", "id": "A2AJA9", "url": "https://www.uniprot.org/uniprot/A2AJA9" } ], "reference": [ { "type": "PubMed", "id": "24129315", "url": "https://glygen.org/publication/PubMed/24129315" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "A2AJA9", "url": "https://oglcnac.org/atlas/detail/A2AJA9" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "A2AJA9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A2AJA9" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "A2AJA9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A2AJA9" }, { "database": "O-GlcNAc Atlas", "id": "A2AJA9", "url": "https://oglcnac.org/atlas/detail/A2AJA9" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] } ], "pathway": [ { "id": "mmu:381353", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:381353", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZXP9-1", "protein_name": "Apical junction component 1 homolog", "gene_name": "Ajm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRTDPPDLLVSTVYQDIKVVDPGLTSKRQPCERSVARPAASTPFNKRHCRSFDFLEALDEPTMETHPEPPPPEPAPPRARPRDGEPRRRTRSKSAPRVPQSLTTAPASPPVLQRRGREAQRAVRVEGSPCREPSYPALRALANELHPIKLQPQRGGPGRIAPLCATPGRCAPPESSAGPVPHVRCRLDIKPDEAVLQHAARSSRSGAPRETSSWARTVPQFHGLTVPGPRHVALSRTPTPSDLYCTDPRPLYCDGPLPGPRDYLEHRTQPFTTPPGPTQFFYTEEPEGYAGSFTASPGLPFDGYCSRPYLSEEPPRPSPRRGGSYYAGEVRTFPIQEPPSRSYYGETTRAYGLPFVPRYVPEEPRVHPGARAFYTEDFGRYRERDALARTYPHPRSSPTWADWGPRPYRTLQVMPPPAPGPLLASWHGGTGTSPPRLVTDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVRDTRGSSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRTGECLGRNWYVTPEITITDNDLRSAERPTAKGWELPGGRPRQPVPVVPEGPASSRQRSLEQLDELITDLVIDSRSPAQAPEPTAEGLGRQLRRLLDSRPAGPGGATALAPSRSPPASAGSTEEPTGSGEAAEASPEPSADEDDLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCRHVLQFCRDSSPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYLSLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPGAAPPGAAARPAPRSPGPTVRKFAKVALAAGSPTRPPPARGGEPDMETLILTPPPGTAGLDEEGEAGRRAREVAFIHIQRELRLRGVFLRHEFPRVYEQLCEFVEANRRFTPTTIYPTDRRTGRPFMCMIMAASEPRALDWVASANLLDDIM", "length": 974 }, 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"evidence": [ { "id": "A2AJA9", "url": "https://omabrowser.org/oma/group/A2AJA9/", "database": "OMA" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A2AJA9", "url": "https://www.uniprot.org/uniprot/A2AJA9" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A2AJA9", "url": "https://www.uniprot.org/uniprot/A2AJA9" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A2AJA9", "url": "https://www.uniprot.org/uniprot/A2AJA9" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": 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[], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 5 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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