{
    "uniprot_canonical_ac": "A2AB59-1",
    "uniprot_ac": "A2AB59",
    "uniprot_id": "RHG27_MOUSE",
    "mass": {
        "chemical_mass": 97049.0,
        "monoisotopic_mass": 97049.0
    },
    "refseq": {
        "ac": "NP_001192165",
        "name": "rho GTPase-activating protein 27 isoform 1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192165"
    },
    "gene_names": [
        {
            "name": "Arhgap27",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2AB59",
            "id": "A2AB59"
        },
        {
            "name": "2310069I04Rik; 5730442P18Rik; Gm21552; Sh3d20",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192165",
            "id": "NP_001192165"
        },
        {
            "name": "5730442P18Rik",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2AB59",
            "id": "A2AB59"
        },
        {
            "name": "Arhgap27",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192165",
            "id": "NP_001192165"
        },
        {
            "name": "Camgap1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2AB59",
            "id": "A2AB59"
        },
        {
            "name": "Sh3d20",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2AB59",
            "id": "A2AB59"
        }
    ],
    "protein_names": [
        {
            "name": "Rho GTPase-activating protein 27",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "A2AB59"
        },
        {
            "name": "CIN85-associated multi-domain-containing Rho GTPase-activating protein 1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A2AB59"
        },
        {
            "name": "Rho-type GTPase-activating protein 27",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A2AB59"
        },
        {
            "name": "rho GTPase-activating protein 27 isoform 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192165",
            "id": "NP_001192165"
        },
        {
            "name": "rho GTPase-activating protein 27 isoform 3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_899111",
            "id": "NP_899111"
        },
        {
            "name": "rho-type GTPase-activating protein 27; CIN85-associated multi-domain-containing Rho GTPase-activating protein 1; SH3 domain containing 20",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_899111",
            "id": "NP_899111"
        }
    ],
    "function": [
        {
            "annotation": "Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AB59",
                    "url": "https://www.uniprot.org/uniprot/A2AB59#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AB59",
                    "url": "https://www.uniprot.org/uniprot/A2AB59"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Arhgap27",
            "url": "https://www.uniprot.org/uniprot/A2AB59",
            "locus": {
                "chromosome": "11",
                "start_pos": 103222323,
                "end_pos": 103254518,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000034255",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000034255"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000034255",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000034255",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd00201",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd04403",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04403",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd12069",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12069",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd13233",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13233",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "544817",
            "url": "https://www.ncbi.nlm.nih.gov/gene/544817",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000198",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001202",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001452",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR001849",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR008936",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR011047",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR011993",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036020",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036028",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:544817",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:544817",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "1916903",
            "url": "http://www.informatics.jax.org/marker/MGI:1916903",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "AWHKAIT",
            "url": "https://omabrowser.org/oma/group/AWHKAIT/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "3686961at2759",
            "url": "http://www.orthodb.org/?query=3686961at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5395569at2759",
            "url": "http://www.orthodb.org/?query=5395569at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23176",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23176",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23176:SF104",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23176:SF104",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00169",
            "url": "http://pfam.xfam.org/family/PF00169",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00397",
            "url": "http://pfam.xfam.org/family/PF00397",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00620",
            "url": "http://pfam.xfam.org/family/PF00620",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF14604",
            "url": "http://pfam.xfam.org/family/PF14604",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_A2AB59",
            "url": "http://purl.obolibrary.org/obo/PR_A2AB59",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-MMU-9013148",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9013148",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-9013149",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9013149",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001192165",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192165",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A2AB59",
            "url": "https://www.uniprot.org/uniprot/A2AB59",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A2AB59-1",
            "url": "https://www.uniprot.org/uniprot/A2AB59-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A2AB59-2",
            "url": "https://www.uniprot.org/uniprot/A2AB59-2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A2AB70",
            "url": "https://www.uniprot.org/uniprot/A2AB70",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A2AB70-1",
            "url": "https://www.uniprot.org/uniprot/A2AB70-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A2AKN5",
            "url": "https://www.uniprot.org/uniprot/A2AKN5",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A2AKN5-1",
            "url": "https://www.uniprot.org/uniprot/A2AKN5-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9Q6V8",
            "url": "https://www.uniprot.org/uniprot/E9Q6V8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9Q6V8-1",
            "url": "https://www.uniprot.org/uniprot/E9Q6V8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MAADVEGDVYVLVEHPFEYTGKDGRRIAIQPNERYRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGDPAPAPQPSVPQQRPAVPEPLAYDYRFVSTPVGADGSSAEPRGRASSLCGPARQRTGGQRNSLAPGGPACLYVRPAAPVRPAQSLDDLARGGTAPPAGLLGSAGHFKASSVAGSWVCPRPLAPSDSENVYEAIPDLRCPPRAESPKQVDDPPEPVYANVERQPRATSPRSAAAPPRLSPVWETHTDTGTGRPYYYNPDTGVTTWESPFETPEGTTSPATSRASVGSGESLETEWGQYWDEESRRVFFYNPLTGETAWEDETEELEEDHQEQLEMQPSLSPRSPGQQRPPTPETDYPELLASYPEEDYSPVGSFSDPGPASPLVAPPGWSCQITPDKQMLYTNQFTQEQWVRLEDQHGKPYFYNPEDSSVQWELPQVPIPAPRSVRKSSQDSDTPAQASPPEEKIKTLDKAGVLHRTKTVDKGKRLRKKHWSTSWTVLEGGVLTFFKDSKTSAAGGLRQPSKLSTPEYTVELKGASLSWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGISELSADLLQGEEGEPSSADFGSSERLGSWREEDVRQNAASPSLSPGGLESDLSRVRHKLRKFLQRRPTLQSLRDKGYIKDQVFGCALAQLCERERSPVPRFVQQCIRTVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRSRCVRDLVRTLPAPNQDTLRLLIQHLCRVIEHGEQNRMTVQNVAIVFGPTLLRPEMEEASMPMTMVFQNQVVELILHQCADIFPPH",
        "length": 869,
        "header": "sp|A2AB59-1|RHG27_MOUSE Isoform 1 of Rho GTPase-activating protein 27  OS=Mus musculus OX=10090 GN=Arhgap27 PE=1 SV=1 CANONICAL=A2AB59-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A2AB59-1",
            "url": "",
            "sequence": {
                "sequence": "MAADVEGDVYVLVEHPFEYTGKDGRRIAIQPNERYRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGDPAPAPQPSVPQQRPAVPEPLAYDYRFVSTPVGADGSSAEPRGRASSLCGPARQRTGGQRNSLAPGGPACLYVRPAAPVRPAQSLDDLARGGTAPPAGLLGSAGHFKASSVAGSWVCPRPLAPSDSENVYEAIPDLRCPPRAESPKQVDDPPEPVYANVERQPRATSPRSAAAPPRLSPVWETHTDTGTGRPYYYNPDTGVTTWESPFETPEGTTSPATSRASVGSGESLETEWGQYWDEESRRVFFYNPLTGETAWEDETEELEEDHQEQLEMQPSLSPRSPGQQRPPTPETDYPELLASYPEEDYSPVGSFSDPGPASPLVAPPGWSCQITPDKQMLYTNQFTQEQWVRLEDQHGKPYFYNPEDSSVQWELPQVPIPAPRSVRKSSQDSDTPAQASPPEEKIKTLDKAGVLHRTKTVDKGKRLRKKHWSTSWTVLEGGVLTFFKDSKTSAAGGLRQPSKLSTPEYTVELKGASLSWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGISELSADLLQGEEGEPSSADFGSSERLGSWREEDVRQNAASPSLSPGGLESDLSRVRHKLRKFLQRRPTLQSLRDKGYIKDQVFGCALAQLCERERSPVPRFVQQCIRTVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRSRCVRDLVRTLPAPNQDTLRLLIQHLCRVIEHGEQNRMTVQNVAIVFGPTLLRPEMEEASMPMTMVFQNQVVELILHQCADIFPPH",
                "length": 869,
                "header": "sp|A2AB59-1|RHG27_MOUSE Isoform 1 of Rho GTPase-activating protein 27  OS=Mus musculus OX=10090 GN=Arhgap27 PE=1 SV=1 CANONICAL=A2AB59-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 103251726,
                "end_pos": 103223692,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000107024",
                        "url": "https://www.ensembl.org/id/ENSMUST00000107024"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000102639",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000102639"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A2AB59-2",
            "url": "",
            "sequence": {
                "sequence": "MVDMISKLVRRQSRALRAQVDDPPEPVYANVERQPRATSPRSAAAPPRLSPVWETHTDTGTGRPYYYNPDTGVTTWESPFETPEGTTSPATSRASVGSGESLETEWGQYWDEESRRVFFYNPLTGETAWEDETEELEEDHQEQLEMQPSLSPRSPGQQRPPTPETDYPELLASYPEEDYSPVGSFSDPGPASPLVAPPGWSCQITPDKQMLYTNQFTQEQWVRLEDQHGKPYFYNPEDSSVQWELPQVPIPAPRSVRKSSQDSDTPAQASPPEEKIKTLDKAGVLHRTKTVDKGKRLRKKHWSTSWTVLEGGVLTFFKDSKTSAAGGLRQPSKLSTPEYTVELKGASLSWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGISELSADLLQGEEGEPSSADFGSSERLGSWREEDVRQNAASPSLSPGGLESDLSRVRHKLRKFLQRRPTLQSLRDKGYIKDQVFGCALAQLCERERSPVPRFVQQCIRTVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRSRCVRDLVRTLPAPNQDTLRLLIQHLCRVIEHGEQNRMTVQNVAIVFGPTLLRPEMEEASMPMTMVFQNQVVELILHQCADIFPPH",
                "length": 670,
                "header": "sp|A2AB59-2|RHG27_MOUSE Isoform 2 of Rho GTPase-activating protein 27  OS=Mus musculus OX=10090 GN=Arhgap27 PE=1 SV=1 CANONICAL=A2AB59-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 103235392,
                "end_pos": 103223692,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000041385",
                        "url": "https://www.ensembl.org/id/ENSMUST00000041385"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000039427",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000039427"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A2AB70-1",
            "url": "",
            "sequence": {
                "sequence": "MQTAPEALLLSSDRAWTETPPEPSFLPPQPAGTVDDPPEPVYANVERQPRATSPRSAAAPPRLSPVWETHTDTGTGRPYYYNPDTGVTTWESPFETPEGTTSPATSRASVGSGESLETEWGQY",
                "length": 123,
                "header": "tr|A2AB70-1|RHG27_MOUSE Computationally mapped isoform of Rho GTPase-activating protein 27  OS=Mus musculus OX=10090 GN=Arhgap27 PE=1 SV=1 CANONICAL=A2AB59-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 103247191,
                "end_pos": 103230961,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000107023.3",
                        "url": "https://www.ensembl.org/id/ENSMUST00000107023.3"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000102638.3",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000102638.3"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A2AKN5-1",
            "url": "",
            "sequence": {
                "sequence": "MAADVEGDVYVLVEHPFEYTGKDGRRIAIQPNERYRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGDPAPAPQPSVPQQRPAVPEPLAYDYRFVSTPVGADGSSAEPRGRASSLCGPARQRTGGQRNSLAPGGPACLYVRPAAPVRPAQSLDDLARGGTAPPAGLLGSAGHFKASSVAGSWVCPRPLAPSDSENVYEAIPDLRCPPRAESPKQVGRCERGGRREVTVQQSLDAFFFFN",
                "length": 243,
                "header": "tr|A2AKN5-1|RHG27_MOUSE Computationally mapped isoform of Rho GTPase-activating protein 27  OS=Mus musculus OX=10090 GN=Arhgap27 PE=1 SV=1 CANONICAL=A2AB59-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 103251726,
                "end_pos": 103250998,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000092557.6",
                        "url": "https://www.ensembl.org/id/ENSMUST00000092557.6"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000102637.3",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000102637.3"
                    }
                ]
            }
        },
        {
            "isoform_ac": "E9Q6V8-1",
            "url": "",
            "sequence": {
                "sequence": "MQPSLSPRSPGQQRPPTPETDYPELLASYPEEDYSPVGSFSDPGPASPLVAPPGWSCQITPDKQMLYTNQFTQEQWVRLEDQHGKPYFYNP",
                "length": 91,
                "header": "tr|E9Q6V8-1|RHG27_MOUSE Computationally mapped isoform of Rho GTPase-activating protein 27  OS=Mus musculus OX=10090 GN=Arhgap27 PE=1 SV=1 CANONICAL=A2AB59-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 103230852,
                "end_pos": 103230055,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000136491.3",
                        "url": "https://www.ensembl.org/id/ENSMUST00000136491.3"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000128051.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000128051.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [
        {
            "start_pos": 155,
            "end_pos": 155,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
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        {
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                },
                {
                    "database": "iPTMnet",
                    "id": "A2AB59",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AB59"
                }
            ],
            "site_lbl": "Thr464"
        },
        {
            "start_pos": 469,
            "end_pos": 469,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
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                {
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                {
                    "database": "PubMed",
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                },
                {
                    "database": "iPTMnet",
                    "id": "A2AB59",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AB59"
                }
            ],
            "site_lbl": "Ser469"
        },
        {
            "start_pos": 632,
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            "kinase_uniprot_canonical_ac": "",
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                {
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                },
                {
                    "database": "PubMed",
                    "id": "21183079",
                    "url": "https://glygen.org/publication/PubMed/21183079"
                },
                {
                    "database": "iPTMnet",
                    "id": "A2AB59",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AB59"
                }
            ],
            "site_lbl": "Ser632"
        },
        {
            "start_pos": 636,
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            "kinase_uniprot_canonical_ac": "",
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                {
                    "database": "UniProtKB",
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                {
                    "database": "PubMed",
                    "id": "21183079",
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                {
                    "database": "iPTMnet",
                    "id": "A2AB59",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AB59"
                }
            ],
            "site_lbl": "Ser636"
        }
    ],
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    "keywords": [],
    "publication": [
        {
            "title": "Identification and characterization of a novel Rho GTPase activating protein implicated in receptor-mediated endocytosis.",
            "journal": "FEBS Lett.",
            "date": "2004",
            "authors": "Sakakibara T, Nemoto Y, Nukiwa T, Takeshima H",
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                    "database": "UniProtKB",
                    "id": "A2AB59",
                    "url": "https://www.uniprot.org/uniprot/A2AB59"
                }
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                {
                    "type": "PubMed",
                    "id": "15147912",
                    "url": "https://glygen.org/publication/PubMed/15147912"
                }
            ]
        },
        {
            "title": "Large-scale phosphorylation analysis of mouse liver.",
            "journal": "Proceedings of the National Academy of Sciences of the United States of America",
            "date": "2007",
            "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP",
            "evidence": [
                {
                    "database": "UniProtKB",
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                    "url": "https://www.uniprot.org/uniprot/A2AB59"
                },
                {
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                }
            ],
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                {
                    "type": "PubMed",
                    "id": "17242355",
                    "url": "https://glygen.org/publication/PubMed/17242355"
                }
            ]
        },
        {
            "title": "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.",
            "journal": "J. Proteome Res.",
            "date": "2008",
            "authors": "Ballif BA, Carey GR, Sunyaev SR, Gygi SP",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AB59",
                    "url": "https://www.uniprot.org/uniprot/A2AB59"
                }
            ],
            "reference": [
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                    "type": "PubMed",
                    "id": "18034455",
                    "url": "https://glygen.org/publication/PubMed/18034455"
                }
            ]
        },
        {
            "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.",
            "journal": "Cell",
            "date": "2010",
            "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AB59",
                    "url": "https://www.uniprot.org/uniprot/A2AB59"
                },
                {
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                    "type": "PubMed",
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                    "url": "https://glygen.org/publication/PubMed/21183079"
                }
            ]
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    ],
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            "id": "mmu:544817",
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            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:544817",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-MMU-9013148",
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        },
        {
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                    "id": "45231495",
                    "url": "http://www.informatics.jax.org/homology/45231495",
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            "sequence": {
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                    "id": "A2AB59",
                    "url": "https://omabrowser.org/oma/group/A2AB59/",
                    "database": "OMA"
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            ],
            "common_name": "Human"
        }
    ],
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                "name": "Molecular Function",
                "total": 2,
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                                "id": "A2AB59",
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                            }
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                ]
            },
            {
                "name": "Cellular Component",
                "total": 3,
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                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
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                    {
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                    {
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                            }
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                ]
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            {
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                    {
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                                "url": "https://www.uniprot.org/uniprot/A2AB59"
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                        "pmid": ""
                    },
                    {
                        "name": "regulation of GTPase activity",
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                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of GTPase activity",
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                        ],
                        "pmid": ""
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                    {
                        "name": "receptor-mediated endocytosis",
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                            {
                                "database": "UniProtKB",
                                "id": "A2AB59",
                                "url": "https://www.uniprot.org/uniprot/A2AB59"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
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    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
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        {
            "name": "homologset.oma",
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    ],
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